| Definition | Shewanella sp. MR-4 chromosome, complete genome. |
|---|---|
| Accession | NC_008321 |
| Length | 4,706,287 |
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The map label for this gene is cysG [H]
Identifier: 113969730
GI number: 113969730
Start: 1615093
End: 1616004
Strand: Direct
Name: cysG [H]
Synonym: Shewmr4_1388
Alternate gene names: 113969730
Gene position: 1615093-1616004 (Clockwise)
Preceding gene: 113969729
Following gene: 113969731
Centisome position: 34.32
GC content: 53.29
Gene sequence:
>912_bases ATGCAATACTTCCCGCTGTTTATTGATACTGTTAATTTAAATGTCCTGCTGGTGGGAGCGGGTGATGTCGCCAGTCGTAA GCTGGCCTTACTGACGCGTACCGAAGCTAATATCCATGTGATTGCCCCCGAGGTAAATCCCGAGGTAAAAGCCTATGCCG ATGCGGGCAGGATTTTATTGTCTGAGCGGCCCGTGGTGCAGGCCGATATTCAAAACTATGATCTCATCTATCTAGCGACC GCAAATGATAAGCTCAACGCCGAATTAGCTACCTTAGCTACCGAGCGGGGGATTTGGGTCAATGCCGTGGATAACCCCGC CTATTGCCGCTTTATTACCCCATCGATTGTCGATAGGGGGCGTCTTGTGGTGGCGATCAGCACTGCGGGCGCAGCACCCG TGTTTGCGCGTACCATTCGGGCCCGCTTAGAGACCAGCCTGCCGCAATCCCTTAAGCCCTTGTTCGACTTCGTGGCCGAC AAGCGTCTCGAAGTACAGCAAAGACTCACCAAAACTGCGACGCGCCGACTATTTTGGGAGCGCTTTTTCGACACCAATGG CGATAGATTTGATGCGCGTACCCCCGAGCATTATCAGAATGCCTTTAACCATATCGTCAGCCGCGGGGAAATCCTATTGT TGGATAATGCTACGCCCGTCGAGTTATTGCCGCTGGCGGCCATGCCCTTGTTACAGCGCCTCGATTGGATTTACAGCGAA GTAGGTTTAGCCGATGACTTGGCTGAACTGGTGCGCCGCGATGCTAATCGCGCAGCGCTGCCTGCGCTGAGTGATATCAG CCGTGAATATGAGCAAGGCTCACGCATGTTGTTGGTCGCCGATACCCAAAAGATTGAGCAACTTAAGGCGCATTTTCTGG TGGCCAAACATTTACGCCCCGGCGCGATTTAG
Upstream 100 bases:
>100_bases TGGCCTCCTTGATTGGGGGTTATAAAGGCTGGATCCAACGCCAGCTGCCCGTGGTGCAAGATTAATTTAGGCTGGGTTTA ACTTTTTATAGGCGAGTCAC
Downstream 100 bases:
>100_bases TCTTCTTTATCGCAGTTTGTTTGAGCTGACGGCGAGTCTTAGGTAGACTCGCCGTTATTTTTTATCGTTAAGTTTAGGAT GTACTATGGCTCTCAAAGCG
Product: siroheme synthase
Products: NA
Alternate protein names: Uroporphyrinogen-III C-methyltransferase; Urogen III methylase; SUMT; Uroporphyrinogen III methylase; UROM; Precorrin-2 dehydrogenase; Sirohydrochlorin ferrochelatase [H]
Number of amino acids: Translated: 303; Mature: 303
Protein sequence:
>303_residues MQYFPLFIDTVNLNVLLVGAGDVASRKLALLTRTEANIHVIAPEVNPEVKAYADAGRILLSERPVVQADIQNYDLIYLAT ANDKLNAELATLATERGIWVNAVDNPAYCRFITPSIVDRGRLVVAISTAGAAPVFARTIRARLETSLPQSLKPLFDFVAD KRLEVQQRLTKTATRRLFWERFFDTNGDRFDARTPEHYQNAFNHIVSRGEILLLDNATPVELLPLAAMPLLQRLDWIYSE VGLADDLAELVRRDANRAALPALSDISREYEQGSRMLLVADTQKIEQLKAHFLVAKHLRPGAI
Sequences:
>Translated_303_residues MQYFPLFIDTVNLNVLLVGAGDVASRKLALLTRTEANIHVIAPEVNPEVKAYADAGRILLSERPVVQADIQNYDLIYLAT ANDKLNAELATLATERGIWVNAVDNPAYCRFITPSIVDRGRLVVAISTAGAAPVFARTIRARLETSLPQSLKPLFDFVAD KRLEVQQRLTKTATRRLFWERFFDTNGDRFDARTPEHYQNAFNHIVSRGEILLLDNATPVELLPLAAMPLLQRLDWIYSE VGLADDLAELVRRDANRAALPALSDISREYEQGSRMLLVADTQKIEQLKAHFLVAKHLRPGAI >Mature_303_residues MQYFPLFIDTVNLNVLLVGAGDVASRKLALLTRTEANIHVIAPEVNPEVKAYADAGRILLSERPVVQADIQNYDLIYLAT ANDKLNAELATLATERGIWVNAVDNPAYCRFITPSIVDRGRLVVAISTAGAAPVFARTIRARLETSLPQSLKPLFDFVAD KRLEVQQRLTKTATRRLFWERFFDTNGDRFDARTPEHYQNAFNHIVSRGEILLLDNATPVELLPLAAMPLLQRLDWIYSE VGLADDLAELVRRDANRAALPALSDISREYEQGSRMLLVADTQKIEQLKAHFLVAKHLRPGAI
Specific function: Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into si
COG id: COG1648
COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the precorrin methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1789768, Length=268, Percent_Identity=35.0746268656716, Blast_Score=144, Evalue=5e-36,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000878 - InterPro: IPR014777 - InterPro: IPR014776 - InterPro: IPR006366 - InterPro: IPR016040 - InterPro: IPR019478 - InterPro: IPR006367 - InterPro: IPR003043 [H]
Pfam domain/function: PF10414 CysG_dimeriser; PF00590 TP_methylase [H]
EC number: =2.1.1.107; =1.3.1.76; =4.99.1.4 [H]
Molecular weight: Translated: 33925; Mature: 33925
Theoretical pI: Translated: 6.69; Mature: 6.69
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQYFPLFIDTVNLNVLLVGAGDVASRKLALLTRTEANIHVIAPEVNPEVKAYADAGRILL CCEEEEEEEEEEEEEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCEEHHCCCEEEE SERPVVQADIQNYDLIYLATANDKLNAELATLATERGIWVNAVDNPAYCRFITPSIVDRG CCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECHHHHCCC RLVVAISTAGAAPVFARTIRARLETSLPQSLKPLFDFVADKRLEVQQRLTKTATRRLFWE EEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH RFFDTNGDRFDARTPEHYQNAFNHIVSRGEILLLDNATPVELLPLAAMPLLQRLDWIYSE HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH VGLADDLAELVRRDANRAALPALSDISREYEQGSRMLLVADTQKIEQLKAHFLVAKHLRP CCCHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCC GAI CCC >Mature Secondary Structure MQYFPLFIDTVNLNVLLVGAGDVASRKLALLTRTEANIHVIAPEVNPEVKAYADAGRILL CCEEEEEEEEEEEEEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCEEHHCCCEEEE SERPVVQADIQNYDLIYLATANDKLNAELATLATERGIWVNAVDNPAYCRFITPSIVDRG CCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECHHHHCCC RLVVAISTAGAAPVFARTIRARLETSLPQSLKPLFDFVADKRLEVQQRLTKTATRRLFWE EEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH RFFDTNGDRFDARTPEHYQNAFNHIVSRGEILLLDNATPVELLPLAAMPLLQRLDWIYSE HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH VGLADDLAELVRRDANRAALPALSDISREYEQGSRMLLVADTQKIEQLKAHFLVAKHLRP CCCHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCC GAI CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA