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The map label for this gene is sstT [H]

Identifier: 113969715

GI number: 113969715

Start: 1601658

End: 1602884

Strand: Direct

Name: sstT [H]

Synonym: Shewmr4_1373

Alternate gene names: 113969715

Gene position: 1601658-1602884 (Clockwise)

Preceding gene: 113969714

Following gene: 113969716

Centisome position: 34.03

GC content: 48.25

Gene sequence:

>1227_bases
ATGAAACAAGAATCATCTTTTTTAGCCAAGTTGGCTAATGGCAGTTTGGTGCTGCAAATTCTCGTGGGGATCATCGCTGG
TGTGAGTCTAGCCAGCTTTTCACATGAAGCCGCTAAGCAAGTCGCGTTTTTAGGTAGTCTGTTTGTGGGTGCGTTAAAAG
CCATTGCACCTATTCTAGTGTTTATCTTAGTTGCGTCGTCTATTGCCAATCAAAAGAAAAATACCCAAACCAATATGCGC
CCGATCGTGGTGCTGTACTTATTTGGCACCTTCGCTGCCGCCTTAACCGCGGTACTGCTGAGCATGATGTTCCCGACCAA
CCTAGTGTTGGTTGCCGGCGTGGAGGGCACCAGTCCACCGCAGGGTATTGGTGAAGTGTTAAATACCTTACTCTTCAAAC
TGGTCGATAACCCAGTTAATGCCTTAATGACGGGTAACTACATCGGCATTTTGGCATGGGGTGTGGGTTTAGGTTTAGCA
CTGCACCATGCGAGCGATTCGACCAAACAAGTGTTTGCCGATGTGAGCCATGGTATTTCGCAAATGGTGCGTTTTATCAT
TCGTTTAGCGCCAATCGGTATTTTTGGTTTGGTAGCAGCGACATTTGCCGAAACTGGTTTTGCGGCGATAGCCGGCTATG
CCAAATTATTGGCCGTGTTACTCGGCGCGATGGCAATTATCGCATTGATTGTTAACCCGCTGATTGTTTACGTGAAAATC
AAACGTAATCCCTATCCTTTAGTGATCCGTTGTTTGCGCGAAAGTGGCGTAACCGCATTTTTCACCCGTTCAAGTGCGGC
GAACATTCCGGTGAACATGGCGCTGTGTGAAAAATTAAAGCTGCATGAAGACACCTATTCTGTCTCAATCCCGCTAGGCG
CAACTATTAACATGGGCGGTGCGGCGATTACCATTACTGTGCTGACCTTAGCCGCAGCCCATACCTTAGGCATTCAGGTG
GATTTATTAACGGCATTACTGCTCAGTGTAGTGGCGGCGATTTCGGCCTGTGGTGCATCCGGTGTGGCTGGTGGTTCGTT
ACTGCTTATTCCGCTGGCCTGTAGCCTGTTTGGTATTTCCAATGATGTGGCCATGCAAGTGGTTGCCGTTGGCTTTATTA
TCGGGGTTATCCAAGATGCGGCCGAAACCGCACTGAATAGTTCTACGGACGTGATTTTTACCGCCGCAGCTTGTGAAGCC
GCTGAAAACAAAGCTAAACTTGGATAA

Upstream 100 bases:

>100_bases
TAGACAAGTTCCACCGCATCCTATAAAACCTTATTGGCCTCAATTTTGAAGGTGTGGGGTGGGGAAACTCAGCCGAAATA
TAATAACGATAGGTTAAGTA

Downstream 100 bases:

>100_bases
AGTGTGCTGTTGTTAGTGTAGAAAAAGTATCATAAGAGCAGTCACCTCGGTGGCTGCTTTTTTTATGGGAGTAGTTATGA
TCCTTTTCGATTTTAAGGAC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPPQGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHASDSTKQVFADVSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKI
KRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGGAAITITVLTLAAAHTLGIQV
DLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG

Sequences:

>Translated_408_residues
MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPPQGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHASDSTKQVFADVSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKI
KRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGGAAITITVLTLAAAHTLGIQV
DLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG
>Mature_408_residues
MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPPQGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHASDSTKQVFADVSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKI
KRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGGAAITITVLTLAAAHTLGIQV
DLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=271, Percent_Identity=26.1992619926199, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI223468566, Length=263, Percent_Identity=28.1368821292776, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=27.9527559055118, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI5032093, Length=265, Percent_Identity=27.9245283018868, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI169790839, Length=427, Percent_Identity=23.1850117096019, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789473, Length=403, Percent_Identity=65.2605459057072, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1790514, Length=403, Percent_Identity=24.5657568238213, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789947, Length=367, Percent_Identity=26.158038147139, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537407, Length=454, Percent_Identity=24.6696035242291, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71983099, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983106, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71996953, Length=470, Percent_Identity=24.468085106383, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=423, Percent_Identity=23.8770685579196, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 42086; Mature: 42086

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00435 PEROXIDASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILVASSIANQKKNTQTNMRPIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHASDSTKQVFADVSHGIS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGG
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCC
AAITITVLTLAAAHTLGIQVDLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
NDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEAAENKAKLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQESSFLAKLANGSLVLQILVGIIAGVSLASFSHEAAKQVAFLGSLFVGALKAIAPILV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILVASSIANQKKNTQTNMRPIVVLYLFGTFAAALTAVLLSMMFPTNLVLVAGVEGTSPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGIGEVLNTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHASDSTKQVFADVSHGIS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAKLLAVLLGAMAIIALIVNPLIVYVKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KRNPYPLVIRCLRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGG
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCC
AAITITVLTLAAAHTLGIQVDLLTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
NDVAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEAAENKAKLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]