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The map label for this gene is etfA [H]

Identifier: 113969695

GI number: 113969695

Start: 1568483

End: 1569409

Strand: Direct

Name: etfA [H]

Synonym: Shewmr4_1353

Alternate gene names: 113969695

Gene position: 1568483-1569409 (Clockwise)

Preceding gene: 113969694

Following gene: 113969696

Centisome position: 33.33

GC content: 51.46

Gene sequence:

>927_bases
ATGGCCATTTTAGTATTAGCAGAACACGATAATGCGGCACTGAAACTGGATACCGCAAAGGTTGTCACCGCAGCCCGTGC
AATTGGTGATGATGTGCATGTATTGGTGGTTGGCCACCAATGTGGCGCCGTGGCGCAAGCTGCGCAGGCCCTACAAGGCG
TCGCTCAAGTATTGGTCGCCGATAACAGTGCCTATGAAGCGCATTTAGCCGAAAACGTAGCTAAATTGCTGGTGGACTTA
GCACCAAATTACAGCCATATCCTCGCCGCAGCATCAAGTGCCGGTAAAGATACGCTACCGCGTGTGGCTGCCTTGTTAGA
CGTTGCGCAAATTTCTGAAGTGATTGGCGTAGTGAGTAGCGACACCTTTGTTCGCCCGATTTATGCGGGTAACGCTTTAG
CGACAGTACAAAGCCATGACGCGATTAAAGTGATGACAGTCCGTGCCAGTGCCTTCGATGCGGCAGCGCAGGGCAACAGT
GCAGCCGTGACTACTTTAGATAAAGTGTTTGAAGCCAAAACTCAGTTTGTGTCTCAATCATTGACCGTTTCTGCGCGTCC
AGAGTTAGGTAATGCGGGCATTATCGTTTCTGGTGGCCGTGGTATGGGCAGCGGTGAAAACTTTGGTATGTTAGAGCAAT
TGGCGGACAAACTCGGTGCCGCTGTTGGGGCATCTCGCGCCGCGGTTGACGCAGGTTTTGTGCCTAACGATCTGCAAGTG
GGTCAAACCGGTAAGATTGTGGCACCAAATCTCTACATCGCCGTGGGGATTTCGGGTGCGATTCAGCATTTAGCAGGGAT
GAAAGACGCTAAGGTGATTGTGGCAATCAACAAAGATCCTGAAGCGCCAATCTTCCAAGTGGCCGATTATGGTCTCGAAG
CTGACCTGTTCGACGCCGTTCCAGAGTTGATTGCAACTCTAGGTTGA

Upstream 100 bases:

>100_bases
GGTGAAGGTGACGCCGCCTGCCGAACGTAAAGCGGGTATCATGGTTGCGTCTGTAGCTGAGCTGGTTGAAAAGTTAAAGA
ATGAAGCGAAGGTGATCTAA

Downstream 100 bases:

>100_bases
TTTTATCTGTGATCTAAGTCAAAGTAAGCGGCTTTGCGGTGGCAACTGCTTAGCCGCTTATGTTTTTATGTGCCTCACGC
CCGTGCAAGGGCGTTCTTAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAILVLAEHDNAALKLDTAKVVTAARAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDL
APNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNS
AAVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELIATLG

Sequences:

>Translated_308_residues
MAILVLAEHDNAALKLDTAKVVTAARAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDL
APNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNS
AAVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELIATLG
>Mature_307_residues
AILVLAEHDNAALKLDTAKVVTAARAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDLA
PNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSA
AVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQVG
QTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELIATLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=310, Percent_Identity=57.741935483871, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=60.5947955390335, Blast_Score=307, Evalue=9e-84,
Organism=Escherichia coli, GI1786226, Length=298, Percent_Identity=29.5302013422819, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787990, Length=298, Percent_Identity=29.8657718120805, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082157, Length=213, Percent_Identity=31.924882629108, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=54.3408360128617, Blast_Score=314, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6325261, Length=293, Percent_Identity=45.0511945392491, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=60.4501607717042, Blast_Score=351, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=60.4501607717042, Blast_Score=351, Evalue=4e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31379; Mature: 31248

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNAALKLDTAKVVTAARAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVA
CEEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
DNSAYEAHLAENVAKLLVDLAPNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSS
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSAAVTTLDKVFEAKTQFVSQS
CCEEEEEECCCEEEEEECCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELIATLG
HHHHHHCC
>Mature Secondary Structure 
AILVLAEHDNAALKLDTAKVVTAARAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVA
EEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
DNSAYEAHLAENVAKLLVDLAPNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSS
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSAAVTTLDKVFEAKTQFVSQS
CCEEEEEECCCEEEEEECCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELIATLG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]