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The map label for this gene is kpsD [H]

Identifier: 113969658

GI number: 113969658

Start: 1523323

End: 1525836

Strand: Direct

Name: kpsD [H]

Synonym: Shewmr4_1315

Alternate gene names: 113969658

Gene position: 1523323-1525836 (Clockwise)

Preceding gene: 113969657

Following gene: 113969659

Centisome position: 32.37

GC content: 45.15

Gene sequence:

>2514_bases
GTGTTACAACAATTCAAAAAATACATCAAAGCGGTTCCCAAAACCGCAATATTAGTTGGCATCACTGCCACGATATTGAT
GGGCACACAGGCGCAAGCTATTACGCCCTCTCCGCAGATGATAGAGCAATTCAAACAACTACCTAAGTCAGAGCAAGAAC
GTTTAGCTCGCCAATACGGTATTGATCCGTCAATGATCACGGGGGCCTCAACTACTGCTACTGCTGTTGAAAACCCAACT
GTAGTTACGCCACGAACGGAAACTGGTAATAACGTCATCGATCAATCTGAGGACGATAAACTTAACCAGGCAACCAAAAC
GGAAGCTAAGGTTGAAGCGATTGAAAGCAAAAAAGAAGATCAGCTAAAACGCTTTGGCTATGACTTATTTGCTGGTTCTC
CAAGTACGTTTGCTCCCGTTTCTGATGTACCAGTGCCTGCTGAATACATGATGGGCCCCGGTGATACCTTAAATGTGCAG
TTTTTTGGTAAAGAAAATAATCAGTTCACATTAACCGTCGGCCGTGATGGCGCGGTTCAATTTCCTAACTTGGGGCCTAT
TTCACTAGTAGGCTTAACCTTTGCTGAAACACGCGAGTTATTACAGCAAAAGATCAGCCAAAGCATGATAGGTATTGAGT
CCAATATCACTATGGGTGAGTTGCGTTCAATCCGGATTTTTGTTGCCGGTGACGCTTACAAGCCAGGCTCCTATACTGTA
TCGAGTTTATCCACTATTACCCAAGCCTTGTTTATCTCGGGTGGTGTGAACGAAATTGGTAGCTTGCGGGATATCCAATT
AAAGCGCTCTGGTAAAACTATTGGCCGTTTAGACTTGTATGATTTATTGCTTCGTGGCGATGCTTCGGGTGATATGCGAT
TACAATCCGGTGATGTGGTCTTTGTTCCATCTACAGGGGGCACTGTGAGTGTCATTGGCGAAGTGCGTCGCCCTGCCATT
TACGAGCTTAAAAATAACGAAACCATGGCCGATGTGATTAATATGGCCAGTGGCTTAAACCCAGGTGCTTATCCTAAAGC
CAGTACCATCGAACGTTATAGTCGTGAAGCGGTAAAAACCGTAGTAAGCGTAGATTTAACCGAAAACTCAGGCTTAAGTA
CGTTAGCTAAAAATGGCGACTTGCTTAATGTGCGCTCAGCTTCAAGCCGTATTGATAATGCTATTACGGTCTCTGGTGCA
GTAATCCGCCCTGGTAAATATCAATGGACAAATGGTTTAACGGTTGCCGATTTATTGCCTTCTATTTGGGGGGATTTAAC
CATCTCGGCAGACTTGGATTACAGCTTGTTGGTAAGAGAAATCAACCAACGTGGCGATATCGAAGTCGAGCGTATTAACC
TCGGGCGCGCAATTGGTGAACCAAAATCACATTATAATCTTGCGCTAAAGCCACGTGATTCAGTCATCGTATTTGACTAT
GCCGATCGTGAGGAGCTGCTTAAGCCCATTATTAAAAAGTTAAAAGAGCAAAGCCGTTTTGGTGATGCAGCGAAGCTAGT
TAATATCAATGGTAATGTGCGTTTTCCTGGCCAGTATCCAATAACGGTTAATGCCGATGTTAAAGATTTACTCATTGCTG
CAGGCGGGCTAGAAGAAGGTGCATATACCTTATCTGCAGAGCTGACTCGCCAACAAGTGTCTGAGCAAAACGGTGTCACA
GTAGAACATGTGCAACTTAGTTTAGACCGCGTTATGCAAAATGATCCGGCGGCCAATATCAAACTGCAAAGCCGTGACAT
CTTAACCGTACGTACGTTGCCAGACTGGCAAGAAACTCGCTGGGTCACCATTAAAGGTGAAGTCAAATTCCCCGGTACTT
ACAGTATCCAGCGCGGCGAAACCTTAAAACAAGTGCTTGCTCGTGCAGGGGGGATGACGAGTGATGCTGCACCACGCAGT
GCAGTCTTTTTGCGCAAATCTATTCAAGAGAAAGAACAGCAAGAGCTTGCTAAGCTTGCCGATGAATTGCGCCGCGAGAT
TGCCGCAAAGGCCTTGACCAAAGACACGCCTACCGTTGGTTATAACGACGCACAAATGATGTTAAATCAGTTGGAAAACG
TTAAAACGGTTGGTCGTTTGGTTGTCGATATCAATGCGATTGAATTAGGCATCGAAAGTGCCGATTTAATGCTAGAAGAT
GCAGATGCACTCTACATTCCGCCTGCTAACCAAACGGTATCTGTTATGGGCCAGGTGCAACATCCAAGCACTCATCGCTT
TAAATCAGGTTTAACCTATGAACAGTATCTAGCGTTATCCGGTGGGGCACGTAAACGCGCTGACGAATCACGCACTTATA
TATTAAAAGCCGATGGTTCGGTACAAATGCCTGAGTCTTCATTATGGTTTACTGGCGGCAGCTCAATGGAACCTGGTGAC
ACCATCGTTGTACCATTAGATACCGAATACAAAGATAATCTAACGTTGTGGACTCAAGTAACGAGCATTATCTACAACAC
CGCCGTCGCAGTATCCGCAATATCGGGGATATAG

Upstream 100 bases:

>100_bases
GCCTAGACCTTAGAAGTACAATCTTCTCGCAGGGCAAAGCCCGATCAGCTTTTAAAGTTTTTAATGTTTTCCATCATCTT
TACCCAATCGGAGATATCTG

Downstream 100 bases:

>100_bases
GAGATAGAACGCCACTGCGTGGCTCTAGAATCTAGAAGTCGCGTAGCGACGTGCTCTTTCTAGCAGGGCGCAGCCCGCTC
TGGTTTTTCTAGAAGTCGTG

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 837

Protein sequence:

>837_residues
MLQQFKKYIKAVPKTAILVGITATILMGTQAQAITPSPQMIEQFKQLPKSEQERLARQYGIDPSMITGASTTATAVENPT
VVTPRTETGNNVIDQSEDDKLNQATKTEAKVEAIESKKEDQLKRFGYDLFAGSPSTFAPVSDVPVPAEYMMGPGDTLNVQ
FFGKENNQFTLTVGRDGAVQFPNLGPISLVGLTFAETRELLQQKISQSMIGIESNITMGELRSIRIFVAGDAYKPGSYTV
SSLSTITQALFISGGVNEIGSLRDIQLKRSGKTIGRLDLYDLLLRGDASGDMRLQSGDVVFVPSTGGTVSVIGEVRRPAI
YELKNNETMADVINMASGLNPGAYPKASTIERYSREAVKTVVSVDLTENSGLSTLAKNGDLLNVRSASSRIDNAITVSGA
VIRPGKYQWTNGLTVADLLPSIWGDLTISADLDYSLLVREINQRGDIEVERINLGRAIGEPKSHYNLALKPRDSVIVFDY
ADREELLKPIIKKLKEQSRFGDAAKLVNINGNVRFPGQYPITVNADVKDLLIAAGGLEEGAYTLSAELTRQQVSEQNGVT
VEHVQLSLDRVMQNDPAANIKLQSRDILTVRTLPDWQETRWVTIKGEVKFPGTYSIQRGETLKQVLARAGGMTSDAAPRS
AVFLRKSIQEKEQQELAKLADELRREIAAKALTKDTPTVGYNDAQMMLNQLENVKTVGRLVVDINAIELGIESADLMLED
ADALYIPPANQTVSVMGQVQHPSTHRFKSGLTYEQYLALSGGARKRADESRTYILKADGSVQMPESSLWFTGGSSMEPGD
TIVVPLDTEYKDNLTLWTQVTSIIYNTAVAVSAISGI

Sequences:

>Translated_837_residues
MLQQFKKYIKAVPKTAILVGITATILMGTQAQAITPSPQMIEQFKQLPKSEQERLARQYGIDPSMITGASTTATAVENPT
VVTPRTETGNNVIDQSEDDKLNQATKTEAKVEAIESKKEDQLKRFGYDLFAGSPSTFAPVSDVPVPAEYMMGPGDTLNVQ
FFGKENNQFTLTVGRDGAVQFPNLGPISLVGLTFAETRELLQQKISQSMIGIESNITMGELRSIRIFVAGDAYKPGSYTV
SSLSTITQALFISGGVNEIGSLRDIQLKRSGKTIGRLDLYDLLLRGDASGDMRLQSGDVVFVPSTGGTVSVIGEVRRPAI
YELKNNETMADVINMASGLNPGAYPKASTIERYSREAVKTVVSVDLTENSGLSTLAKNGDLLNVRSASSRIDNAITVSGA
VIRPGKYQWTNGLTVADLLPSIWGDLTISADLDYSLLVREINQRGDIEVERINLGRAIGEPKSHYNLALKPRDSVIVFDY
ADREELLKPIIKKLKEQSRFGDAAKLVNINGNVRFPGQYPITVNADVKDLLIAAGGLEEGAYTLSAELTRQQVSEQNGVT
VEHVQLSLDRVMQNDPAANIKLQSRDILTVRTLPDWQETRWVTIKGEVKFPGTYSIQRGETLKQVLARAGGMTSDAAPRS
AVFLRKSIQEKEQQELAKLADELRREIAAKALTKDTPTVGYNDAQMMLNQLENVKTVGRLVVDINAIELGIESADLMLED
ADALYIPPANQTVSVMGQVQHPSTHRFKSGLTYEQYLALSGGARKRADESRTYILKADGSVQMPESSLWFTGGSSMEPGD
TIVVPLDTEYKDNLTLWTQVTSIIYNTAVAVSAISGI
>Mature_837_residues
MLQQFKKYIKAVPKTAILVGITATILMGTQAQAITPSPQMIEQFKQLPKSEQERLARQYGIDPSMITGASTTATAVENPT
VVTPRTETGNNVIDQSEDDKLNQATKTEAKVEAIESKKEDQLKRFGYDLFAGSPSTFAPVSDVPVPAEYMMGPGDTLNVQ
FFGKENNQFTLTVGRDGAVQFPNLGPISLVGLTFAETRELLQQKISQSMIGIESNITMGELRSIRIFVAGDAYKPGSYTV
SSLSTITQALFISGGVNEIGSLRDIQLKRSGKTIGRLDLYDLLLRGDASGDMRLQSGDVVFVPSTGGTVSVIGEVRRPAI
YELKNNETMADVINMASGLNPGAYPKASTIERYSREAVKTVVSVDLTENSGLSTLAKNGDLLNVRSASSRIDNAITVSGA
VIRPGKYQWTNGLTVADLLPSIWGDLTISADLDYSLLVREINQRGDIEVERINLGRAIGEPKSHYNLALKPRDSVIVFDY
ADREELLKPIIKKLKEQSRFGDAAKLVNINGNVRFPGQYPITVNADVKDLLIAAGGLEEGAYTLSAELTRQQVSEQNGVT
VEHVQLSLDRVMQNDPAANIKLQSRDILTVRTLPDWQETRWVTIKGEVKFPGTYSIQRGETLKQVLARAGGMTSDAAPRS
AVFLRKSIQEKEQQELAKLADELRREIAAKALTKDTPTVGYNDAQMMLNQLENVKTVGRLVVDINAIELGIESADLMLED
ADALYIPPANQTVSVMGQVQHPSTHRFKSGLTYEQYLALSGGARKRADESRTYILKADGSVQMPESSLWFTGGSSMEPGD
TIVVPLDTEYKDNLTLWTQVTSIIYNTAVAVSAISGI

Specific function: Involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface. May function as the periplasmic binding element of the PSA transport system, in which it transiently interacts with the membrane component of the t

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli K5 kpsD [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=210, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788376, Length=209, Percent_Identity=24.4019138755981, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 91329; Mature: 91329

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00144 ASN_GLN_ASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQFKKYIKAVPKTAILVGITATILMGTQAQAITPSPQMIEQFKQLPKSEQERLARQYG
CHHHHHHHHHHCCCCEEEEEEHHHHEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHC
IDPSMITGASTTATAVENPTVVTPRTETGNNVIDQSEDDKLNQATKTEAKVEAIESKKED
CCCHHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QLKRFGYDLFAGSPSTFAPVSDVPVPAEYMMGPGDTLNVQFFGKENNQFTLTVGRDGAVQ
HHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCEE
FPNLGPISLVGLTFAETRELLQQKISQSMIGIESNITMGELRSIRIFVAGDAYKPGSYTV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCEEEEEEEECCCCCCCCEEH
SSLSTITQALFISGGVNEIGSLRDIQLKRSGKTIGRLDLYDLLLRGDASGDMRLQSGDVV
HHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCEE
FVPSTGGTVSVIGEVRRPAIYELKNNETMADVINMASGLNPGAYPKASTIERYSREAVKT
EEECCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VVSVDLTENSGLSTLAKNGDLLNVRSASSRIDNAITVSGAVIRPGKYQWTNGLTVADLLP
EEEEEECCCCCCHHHHCCCCEEEEECHHHHCCCEEEECCEEECCCCEECCCCCCHHHHHH
SIWGDLTISADLDYSLLVREINQRGDIEVERINLGRAIGEPKSHYNLALKPRDSVIVFDY
HHHCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCEEEECCCCCEEEEEC
ADREELLKPIIKKLKEQSRFGDAAKLVNINGNVRFPGQYPITVNADVKDLLIAAGGLEEG
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCEEECCCHHHHHEECCCCCCC
AYTLSAELTRQQVSEQNGVTVEHVQLSLDRVMQNDPAANIKLQSRDILTVRTLPDWQETR
CEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCE
WVTIKGEVKFPGTYSIQRGETLKQVLARAGGMTSDAAPRSAVFLRKSIQEKEQQELAKLA
EEEEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DELRREIAAKALTKDTPTVGYNDAQMMLNQLENVKTVGRLVVDINAIELGIESADLMLED
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEHEEECCCCCCEEEEC
ADALYIPPANQTVSVMGQVQHPSTHRFKSGLTYEQYLALSGGARKRADESRTYILKADGS
CCEEEECCCCCEEEEEEECCCCCCHHHHCCCCHHHHEEECCCCCCCCCCCCEEEEECCCC
VQMPESSLWFTGGSSMEPGDTIVVPLDTEYKDNLTLWTQVTSIIYNTAVAVSAISGI
EECCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQQFKKYIKAVPKTAILVGITATILMGTQAQAITPSPQMIEQFKQLPKSEQERLARQYG
CHHHHHHHHHHCCCCEEEEEEHHHHEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHC
IDPSMITGASTTATAVENPTVVTPRTETGNNVIDQSEDDKLNQATKTEAKVEAIESKKED
CCCHHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QLKRFGYDLFAGSPSTFAPVSDVPVPAEYMMGPGDTLNVQFFGKENNQFTLTVGRDGAVQ
HHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCEE
FPNLGPISLVGLTFAETRELLQQKISQSMIGIESNITMGELRSIRIFVAGDAYKPGSYTV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCEEEEEEEECCCCCCCCEEH
SSLSTITQALFISGGVNEIGSLRDIQLKRSGKTIGRLDLYDLLLRGDASGDMRLQSGDVV
HHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCEE
FVPSTGGTVSVIGEVRRPAIYELKNNETMADVINMASGLNPGAYPKASTIERYSREAVKT
EEECCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VVSVDLTENSGLSTLAKNGDLLNVRSASSRIDNAITVSGAVIRPGKYQWTNGLTVADLLP
EEEEEECCCCCCHHHHCCCCEEEEECHHHHCCCEEEECCEEECCCCEECCCCCCHHHHHH
SIWGDLTISADLDYSLLVREINQRGDIEVERINLGRAIGEPKSHYNLALKPRDSVIVFDY
HHHCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCEEEECCCCCEEEEEC
ADREELLKPIIKKLKEQSRFGDAAKLVNINGNVRFPGQYPITVNADVKDLLIAAGGLEEG
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCEEECCCHHHHHEECCCCCCC
AYTLSAELTRQQVSEQNGVTVEHVQLSLDRVMQNDPAANIKLQSRDILTVRTLPDWQETR
CEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCE
WVTIKGEVKFPGTYSIQRGETLKQVLARAGGMTSDAAPRSAVFLRKSIQEKEQQELAKLA
EEEEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DELRREIAAKALTKDTPTVGYNDAQMMLNQLENVKTVGRLVVDINAIELGIESADLMLED
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEHEEECCCCCCEEEEC
ADALYIPPANQTVSVMGQVQHPSTHRFKSGLTYEQYLALSGGARKRADESRTYILKADGS
CCEEEECCCCCEEEEEEECCCCCCHHHHCCCCHHHHEEECCCCCCCCCCCCEEEEECCCC
VQMPESSLWFTGGSSMEPGDTIVVPLDTEYKDNLTLWTQVTSIIYNTAVAVSAISGI
EECCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021185 [H]