Click here to switch to the map view.

The map label for this gene is flhF [H]

Identifier: 113969640

GI number: 113969640

Start: 1504294

End: 1505670

Strand: Direct

Name: flhF [H]

Synonym: Shewmr4_1297

Alternate gene names: 113969640

Gene position: 1504294-1505670 (Clockwise)

Preceding gene: 113969639

Following gene: 113969641

Centisome position: 31.96

GC content: 48.37

Gene sequence:

>1377_bases
GTGAAGATTAAACGTTTTTTTGCCAAAGACATGCGTGCTGCACTGGCCCAAGTGAAGGACACGCTCGGCTCCGATGCCGT
GATTATGTCGAATAAAAAGGTCAATGGTGGCATTGAGATTGTGGCCGCCGTTGATTACGACGAGCCCAAAGCGAAGGCGC
CTGCCGCTGCACCGACTTTTATGGATGTGAGTGATGACTTAGTATCGCTCGGTGCTAAAGCGCCGATTCGTGCTGAAACT
AAGTTAAAACCATCGGCGCCAGCGGACTCTCTCCAGGCATTGCTCGAGAAGCAACAAAGCCGTTTAAACCAACAGCTCAC
CCATCAACAGCAAGACGCCGAACTGCCTGCGTGGGCTAAAGGATTACAAGCACCTGTGGCACCTAAAGCTGAGCGTCGCG
ATATGGGCAATCCTTTCGATAAGAAACCGCAGAGCTCGCCAAAGCAAAATGCGGATCTCGAAGCCATGCGCGATGAATTA
TCATCCTTACGTAATTTGTTGACCCATCAGGTTTCAGCATTGATGACTGAGCATAAAAAACGTATCGACCCTGTCGGTGC
CATGCTGGAGTCAAAGTTGCTGGAAGCCGAGTTTTCTCCAGCTGTCGCGAACAAGTTAGCGGCGCTCAGTCAACACTATA
CCCCTGCAGAATTAGTTCGTGCACTGCCACAAAGTCTAGCGAATATGCTTGATAACCAAGGTGATGATATCGTTAAGCAA
GGTGGTGTTGTTGCGCTGGTAGGTCCAACTGGAGTCGGTAAAACTACGTCATTAGCTAAATTAGCTGCACGCTTTGCGGC
CCATCATGGTGCGGATCAAGTGGCTTTGATTACCACAGACCATTATCGTATTGGCGCCTATGAGCAATTGGCCACCTATG
GCAAAATTATGGGTTGTCCAGTCAAACAAGCCCATGACCTTGCTGAACTAGAACAAATTCTGTATCAGTTCAGAAATCGC
AAGCTAGTATTGATAGATACCGCGGGTATGGGTCAACGAGATATGCGGCTTTACCAGCAACTTGATAATTTAACTGCAAA
TAGCAGAATACCTATCCGCAGTTATCTGGTACTGTCTGCCACAGGACAGCGCCGCGTGCTGCAAGATGCTGTAAATCACT
TTAAACGCATTCCCTTATCTGGTGTTGTACTCACCAAACTCGATGAATCCGTGTCTTTAGCGGGCGCATTAAGTGTGTTG
ATCCAAAGTGGGTTGCCATTAAGTTATGTTACGGATGGGCAGCGAGTGCCCGAAGATATGAAAGTCGCCGATACCTTACT
GCTCGCTGAGCAGGCATTAGCGGCCTTAGAAAACACTGAAGAACAATCGTTACCAGACACAGCGTGGTCAGATAATATGA
CCTGTGCATTTGAGTAG

Upstream 100 bases:

>100_bases
AATATACTATTCCTAATCTCAGAGTGATTTCTTACCAAGAAATCCCCGATGAAAAGCAAATACGCATAGTGTCTGCCGTC
GGCCAGTAGAGGACGCATAA

Downstream 100 bases:

>100_bases
AGTTATGACCCTGGATCAAGCAAGTGGTTTACGTATGATGAATCAACCCTATAACGAAAAAGTGAAAGTAATCGCGGTTA
CGGGTGGTAAAGGTGGCGTG

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIKRFFAKDMRAALAQVKDTLGSDAVIMSNKKVNGGIEIVAAVDYDEPKAKAPAAAPTFMDVSDDLVSLGAKAPIRAET
KLKPSAPADSLQALLEKQQSRLNQQLTHQQQDAELPAWAKGLQAPVAPKAERRDMGNPFDKKPQSSPKQNADLEAMRDEL
SSLRNLLTHQVSALMTEHKKRIDPVGAMLESKLLEAEFSPAVANKLAALSQHYTPAELVRALPQSLANMLDNQGDDIVKQ
GGVVALVGPTGVGKTTSLAKLAARFAAHHGADQVALITTDHYRIGAYEQLATYGKIMGCPVKQAHDLAELEQILYQFRNR
KLVLIDTAGMGQRDMRLYQQLDNLTANSRIPIRSYLVLSATGQRRVLQDAVNHFKRIPLSGVVLTKLDESVSLAGALSVL
IQSGLPLSYVTDGQRVPEDMKVADTLLLAEQALAALENTEEQSLPDTAWSDNMTCAFE

Sequences:

>Translated_458_residues
MKIKRFFAKDMRAALAQVKDTLGSDAVIMSNKKVNGGIEIVAAVDYDEPKAKAPAAAPTFMDVSDDLVSLGAKAPIRAET
KLKPSAPADSLQALLEKQQSRLNQQLTHQQQDAELPAWAKGLQAPVAPKAERRDMGNPFDKKPQSSPKQNADLEAMRDEL
SSLRNLLTHQVSALMTEHKKRIDPVGAMLESKLLEAEFSPAVANKLAALSQHYTPAELVRALPQSLANMLDNQGDDIVKQ
GGVVALVGPTGVGKTTSLAKLAARFAAHHGADQVALITTDHYRIGAYEQLATYGKIMGCPVKQAHDLAELEQILYQFRNR
KLVLIDTAGMGQRDMRLYQQLDNLTANSRIPIRSYLVLSATGQRRVLQDAVNHFKRIPLSGVVLTKLDESVSLAGALSVL
IQSGLPLSYVTDGQRVPEDMKVADTLLLAEQALAALENTEEQSLPDTAWSDNMTCAFE
>Mature_458_residues
MKIKRFFAKDMRAALAQVKDTLGSDAVIMSNKKVNGGIEIVAAVDYDEPKAKAPAAAPTFMDVSDDLVSLGAKAPIRAET
KLKPSAPADSLQALLEKQQSRLNQQLTHQQQDAELPAWAKGLQAPVAPKAERRDMGNPFDKKPQSSPKQNADLEAMRDEL
SSLRNLLTHQVSALMTEHKKRIDPVGAMLESKLLEAEFSPAVANKLAALSQHYTPAELVRALPQSLANMLDNQGDDIVKQ
GGVVALVGPTGVGKTTSLAKLAARFAAHHGADQVALITTDHYRIGAYEQLATYGKIMGCPVKQAHDLAELEQILYQFRNR
KLVLIDTAGMGQRDMRLYQQLDNLTANSRIPIRSYLVLSATGQRRVLQDAVNHFKRIPLSGVVLTKLDESVSLAGALSVL
IQSGLPLSYVTDGQRVPEDMKVADTLLLAEQALAALENTEEQSLPDTAWSDNMTCAFE

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Escherichia coli, GI1789874, Length=191, Percent_Identity=31.9371727748691, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788963, Length=222, Percent_Identity=28.8288288288288, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325345, Length=180, Percent_Identity=25, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 49800; Mature: 49800

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKRFFAKDMRAALAQVKDTLGSDAVIMSNKKVNGGIEIVAAVDYDEPKAKAPAAAPTF
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCC
MDVSDDLVSLGAKAPIRAETKLKPSAPADSLQALLEKQQSRLNQQLTHQQQDAELPAWAK
CCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GLQAPVAPKAERRDMGNPFDKKPQSSPKQNADLEAMRDELSSLRNLLTHQVSALMTEHKK
HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIDPVGAMLESKLLEAEFSPAVANKLAALSQHYTPAELVRALPQSLANMLDNQGDDIVKQ
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHC
GGVVALVGPTGVGKTTSLAKLAARFAAHHGADQVALITTDHYRIGAYEQLATYGKIMGCP
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEECCHHHHHHHHHHHHCCC
VKQAHDLAELEQILYQFRNRKLVLIDTAGMGQRDMRLYQQLDNLTANSRIPIRSYLVLSA
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHEEEEEC
TGQRRVLQDAVNHFKRIPLSGVVLTKLDESVSLAGALSVLIQSGLPLSYVTDGQRVPEDM
CCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
KVADTLLLAEQALAALENTEEQSLPDTAWSDNMTCAFE
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MKIKRFFAKDMRAALAQVKDTLGSDAVIMSNKKVNGGIEIVAAVDYDEPKAKAPAAAPTF
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCC
MDVSDDLVSLGAKAPIRAETKLKPSAPADSLQALLEKQQSRLNQQLTHQQQDAELPAWAK
CCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GLQAPVAPKAERRDMGNPFDKKPQSSPKQNADLEAMRDELSSLRNLLTHQVSALMTEHKK
HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIDPVGAMLESKLLEAEFSPAVANKLAALSQHYTPAELVRALPQSLANMLDNQGDDIVKQ
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHC
GGVVALVGPTGVGKTTSLAKLAARFAAHHGADQVALITTDHYRIGAYEQLATYGKIMGCP
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEECCHHHHHHHHHHHHCCC
VKQAHDLAELEQILYQFRNRKLVLIDTAGMGQRDMRLYQQLDNLTANSRIPIRSYLVLSA
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHEEEEEC
TGQRRVLQDAVNHFKRIPLSGVVLTKLDESVSLAGALSVLIQSGLPLSYVTDGQRVPEDM
CCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
KVADTLLLAEQALAALENTEEQSLPDTAWSDNMTCAFE
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]