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The map label for this gene is flhA [H]

Identifier: 113969639

GI number: 113969639

Start: 1502183

End: 1504282

Strand: Direct

Name: flhA [H]

Synonym: Shewmr4_1296

Alternate gene names: 113969639

Gene position: 1502183-1504282 (Clockwise)

Preceding gene: 113969638

Following gene: 113969640

Centisome position: 31.92

GC content: 48.05

Gene sequence:

>2100_bases
ATGGATGTTAAAGCCTCCCTAGGCCAAGTAAAACAGTTGAAACTGAGCTCTTTCAAGGGCATAGGTACGCCAATGCTAGT
GCTTGCGGCATTGGCTATGATTGTATTGCCTATCCCGCCGTTTCTACTCGACGTTTTATTCTCTTTTAACATTGCCTTGG
CTTTGATTGTTCTTCTTGTCGCGATTTATACCGACAGACCTTTAGATTTTGCTGCTTTCCCAACCGTTTTATTAGTCGCG
ACACTGCTGCGACTCGCGCTTAACGTGGCATCGACCCGTGTAGTATTACTCGAAGGCCATAATGGTGGTGACGCCGCCGG
TAAGGTGATTGAGGCCTTCGGCTCAGTGGTGATTGGCGGTAACTATGCAGTGGGTTTGGTCGTATTTATCATCTTGATCA
TTATCAACTTTGCCGTTGTGACTAAAGGTGCTGGCCGTATTGCCGAGGTGAGTGCTCGCTTTACCTTAGATGCGATGCCC
GGTAAGCAAATGGCCATCGATGCCGACTTGAACGCAGGTATTATTAATCAGGATCAAGCCAGAACCAGACGCGCCGAGGT
GACCCGCGAAGCCGACTTCTATGGCGCAATGGACGGTGCATCTAAGTTTGTGAAGGGCGATGCGATTGCCGGTATCATGA
TTTTGGTTATCAACATTCTCGGTGGGTTTATTATCGGGATTGTGCAACACGGTTTGACATTCTCCCAAGCTGTTGAAATT
TATACCCTGTTAACCATTGGTGACGGTCTCGTCGCACAAATTCCTGGTCTATTACTGTCAATCGCCGCGGCGTTGATGGT
GACCCGTCAAAATGAATCTGGCGATATGGGCCAGATGCTGATTAGTCAGATGTTTGACAGTCACAAGTCACTCAGTATTG
CGGCCGGCGTACTCTTTGTCATGGGTATTGTGCCAGGCATGCCACACATGGCGTTTTTAAGCTTTGCCGTGATCACAGGT
GGTGCCGCTTACTTTATATTTAAACGTAATGAAGCCAAACGTGCCAAAGCCCTTGAGCAAGTCAAAACGGGCCCAGCGGA
AAGAGCCGAAAGAGAACCTAAAGAACTTAGCTGGGACGATGTACACCATGTTGACACTATCGGTCTGGAAGTGGGTTATC
GTTTGATCCCATTAGTCGATAAAGGGCAAGGTGGTGAATTACTAAGTCGGATCAAAGGGGTACGTAAAAAGCTTTCTCAA
GAGCTGGGCTTCTTGGTGCCTGCGGTACATATTCGTGACAACCTCGATTTATCACCCAATGCCTATCGCATCTCGTTAAT
GGGCGTGGTGGTTGGAGAGGCGGATATTCGCCATGACTGCGAACTCGCCATCAACCCAGGCCAAGTTTACGGTAAGCTCG
ATGGTATCGAAACGCGTGATCCTGCCTTTGGTCTCGAAGCCGTGTGGATTGCCCCTGAGCTGCGTGAACATGCACAAACC
TTAGGTTATACCGTGGTGGATGCCGCGACAGTGGTGGCTACCCATATCAGCCAAATATTGACGAATAACGCGGCGAAACT
CTTAGGCTATGAAGAAGTGCAACAACTGATGGATATGCTTGCCAAGCATTCGCCTAAGCTGGTGGATGGCTTTATTCCTG
ATGTGATGCCGCTTGGAAATGTCGTAAAAGTGATGCAAAACCTATTAAATGAAGGAGTTTCTGTCAGAGACTTGCGTACC
ATAGTGCAAACTTTGTTAGAATACGGCACTAAGAGTAACGATACTGAAGTGTTAACGGCGGCAGTACGTATCGCATTGAA
GCGCATGATAGTTCAAGAGATCTCGGGTCCTGAACTTGAAATACCTGTCATAACTTTGGCGCCAGAGTTGGAACAGATGT
TGCATCAGTCAATGCAAGCAACCGGTGGCGATGGCCCAAATATCGAACCTGGTCTTGCGGAGCGTATGCAGCAATCCTTA
GCGGATGCCGCTCAAAAGCAAGAAATGGTTGGTCAGCCCGCTATTTTGCTAACGTCAGGTATGTTACGTGCGACACTGTC
TCGCTTTGTTAAATATACTATTCCTAATCTCAGAGTGATTTCTTACCAAGAAATCCCCGATGAAAAGCAAATACGCATAG
TGTCTGCCGTCGGCCAGTAG

Upstream 100 bases:

>100_bases
AAGAGATAGTTCACAGAGATAAAACCATAACTTGAACTGTTAGCGGTTGGCGCGCTTTTTGCTTCCAGGCTGTTATACGT
CAAAGTTTAGGTATCTGTGA

Downstream 100 bases:

>100_bases
AGGACGCATAAGTGAAGATTAAACGTTTTTTTGCCAAAGACATGCGTGCTGCACTGGCCCAAGTGAAGGACACGCTCGGC
TCCGATGCCGTGATTATGTC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MDVKASLGQVKQLKLSSFKGIGTPMLVLAALAMIVLPIPPFLLDVLFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGIINQDQARTRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLTFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLISQMFDSHKSLSIAAGVLFVMGIVPGMPHMAFLSFAVITG
GAAYFIFKRNEAKRAKALEQVKTGPAERAEREPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGNVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKYTIPNLRVISYQEIPDEKQIRIVSAVGQ

Sequences:

>Translated_699_residues
MDVKASLGQVKQLKLSSFKGIGTPMLVLAALAMIVLPIPPFLLDVLFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGIINQDQARTRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLTFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLISQMFDSHKSLSIAAGVLFVMGIVPGMPHMAFLSFAVITG
GAAYFIFKRNEAKRAKALEQVKTGPAERAEREPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGNVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKYTIPNLRVISYQEIPDEKQIRIVSAVGQ
>Mature_699_residues
MDVKASLGQVKQLKLSSFKGIGTPMLVLAALAMIVLPIPPFLLDVLFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGIINQDQARTRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLTFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLISQMFDSHKSLSIAAGVLFVMGIVPGMPHMAFLSFAVITG
GAAYFIFKRNEAKRAKALEQVKTGPAERAEREPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGNVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKYTIPNLRVISYQEIPDEKQIRIVSAVGQ

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=688, Percent_Identity=52.9069767441861, Blast_Score=703, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75278; Mature: 75278

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKASLGQVKQLKLSSFKGIGTPMLVLAALAMIVLPIPPFLLDVLFSFNIALALIVLLV
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIYTDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGIINQDQA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCCHHH
RTRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLTFSQAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLISQMFDSHKSLSIAAGVLFV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MGIVPGMPHMAFLSFAVITGGAAYFIFKRNEAKRAKALEQVKTGPAERAEREPKELSWDD
HHHCCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCH
VHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
AYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
CEEEEEEEEEECCCCCCCCCEEEECCCHHHEECCCCCCCCCCCCCEEEEECHHHHHHHHH
LGYTVVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGN
HCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCHHCHHH
VVKVMQNLLNEGVSVRDLRTIVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSLADAAQKQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MLRATLSRFVKYTIPNLRVISYQEIPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEEECCCC
>Mature Secondary Structure
MDVKASLGQVKQLKLSSFKGIGTPMLVLAALAMIVLPIPPFLLDVLFSFNIALALIVLLV
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIYTDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGIINQDQA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCCHHH
RTRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLTFSQAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLISQMFDSHKSLSIAAGVLFV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MGIVPGMPHMAFLSFAVITGGAAYFIFKRNEAKRAKALEQVKTGPAERAEREPKELSWDD
HHHCCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCH
VHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
AYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
CEEEEEEEEEECCCCCCCCCEEEECCCHHHEECCCCCCCCCCCCCEEEEECHHHHHHHHH
LGYTVVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGN
HCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCHHCHHH
VVKVMQNLLNEGVSVRDLRTIVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSLADAAQKQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MLRATLSRFVKYTIPNLRVISYQEIPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]