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The map label for this gene is aaeR [H]

Identifier: 113969435

GI number: 113969435

Start: 1281551

End: 1282474

Strand: Direct

Name: aaeR [H]

Synonym: Shewmr4_1091

Alternate gene names: 113969435

Gene position: 1281551-1282474 (Clockwise)

Preceding gene: 113969432

Following gene: 113969436

Centisome position: 27.23

GC content: 53.57

Gene sequence:

>924_bases
ATGGATAGACTCGAAGCGGCAAAGGTGTTTGTGACTATTGTCGAACGAGGGAGCATGATTGGCGCCGCCGAGGCGTTAGA
TATGTCGCGCTCCATGGTGACCCGTTACTTGGCAGAGATGGAAGAATGGTCGGGCGCCCGTTTGTTGCACCGCTCTACAA
GACGTTTGAGCCTGACCGATGCGGGTGAACAAGTGCTCGATTATTGTCAGCGCTTACTTGAGCTGGCGCAGGAAGTCCCT
GCCGTCAGTCATGCTCAGAGTGCCCAGCCCCGAGGGCTACTGCGGATCAGCTGCTCGCAATTTATGGCGCATTTACTCCT
CCCCAGCGTCGTGCGTCCTTATTTAGCTCAATACCCGCAGGCGAGTGTGAACTTTCATGTGACGAGTCAAACCGTTGATT
TAGTAGCTGAACGAATCGATCTTGCCATTCGTATCACCAACGAACTCGACCCTACGCTTATCGCCAGACGTTTAGGCGAG
TGTGAGTCTGTGGTGTGCGCGGCGCCGAGTTATCTTGCCTGCCATTCGGCCATCACGCATCCCGAGAATTTAACTCGGCA
TAACTGCCTAACCTATTCTTACTTTGGCGATGTGATGTGGCGATTCACTCAAACGCCTATCGCCGCGAAGGCAACGTCAA
CGCAGGAAGTCGGGCAGATATTCAATATTCCGGTGAAGGGCAACCTAAGTGCCAATGACTCTATGGTGGTGTTAAACGCC
ACCTTGGCGGGGGAGGGAATTGCCATGCAGCCCCTGTGGGCGGCTAAACCGCACCTCGATTCGGGGGCATTAGTGCCATT
GCTGCGGGAATATAAACCTCAATCCCTCGGCGTGTACGGGGTGTATCAATCCCGCAAACATATGCAGCCCGCATTAAGGG
TGATGATGGATATGCTAGTGCAGCATTTTAATGGGGCAATTTGA

Upstream 100 bases:

>100_bases
TAAACACGGAAAATTGCGCTTGTTTGTTGCATAATTCGGATGAATCGGCGTTGAAAGCCGAGAATCTAGTGCAAGCTAAT
CAACAAGGGGCGAATAAACC

Downstream 100 bases:

>100_bases
GGGCGTGATCTTGAATGCGCGACTTGCGCTTGCATCTCTATGAGATAACGGTGACAGGGTTGCGTTGTTCGTTCGACTCT
GTCCCTCGGTTTACGTCACT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLACHSAITHPENLTRHNCLTYSYFGDVMWRFTQTPIAAKATSTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREYKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI

Sequences:

>Translated_307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLACHSAITHPENLTRHNCLTYSYFGDVMWRFTQTPIAAKATSTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREYKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI
>Mature_307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLACHSAITHPENLTRHNCLTYSYFGDVMWRFTQTPIAAKATSTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREYKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=303, Percent_Identity=33.6633663366337, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87081978, Length=305, Percent_Identity=32.1311475409836, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=29.1946308724832, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786401, Length=308, Percent_Identity=29.5454545454545, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787589, Length=311, Percent_Identity=25.7234726688103, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=24.7422680412371, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=27.7591973244147, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788748, Length=175, Percent_Identity=30.2857142857143, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=264, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787601, Length=135, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34023; Mature: 34023

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTD
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEECCH
AGEQVLDYCQRLLELAQEVPAVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQ
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGECESVVCAAPSYLACHSAITH
CCEEEEEEHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PENLTRHNCLTYSYFGDVMWRFTQTPIAAKATSTQEVGQIFNIPVKGNLSANDSMVVLNA
CHHCCHHCCEEHHHHHHHHHHHHCCCCHHCCCCHHHHHHHEECCCCCCCCCCCCEEEEEE
TLAGEGIAMQPLWAAKPHLDSGALVPLLREYKPQSLGVYGVYQSRKHMQPALRVMMDMLV
EECCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QHFNGAI
HHHCCCC
>Mature Secondary Structure
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTD
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEECCH
AGEQVLDYCQRLLELAQEVPAVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQ
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGECESVVCAAPSYLACHSAITH
CCEEEEEEHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PENLTRHNCLTYSYFGDVMWRFTQTPIAAKATSTQEVGQIFNIPVKGNLSANDSMVVLNA
CHHCCHHCCEEHHHHHHHHHHHHCCCCHHCCCCHHHHHHHEECCCCCCCCCCCCEEEEEE
TLAGEGIAMQPLWAAKPHLDSGALVPLLREYKPQSLGVYGVYQSRKHMQPALRVMMDMLV
EECCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QHFNGAI
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]