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The map label for this gene is ydhC [C]

Identifier: 113969426

GI number: 113969426

Start: 1267072

End: 1268259

Strand: Direct

Name: ydhC [C]

Synonym: Shewmr4_1082

Alternate gene names: 113969426

Gene position: 1267072-1268259 (Clockwise)

Preceding gene: 113969423

Following gene: 113969431

Centisome position: 26.92

GC content: 47.81

Gene sequence:

>1188_bases
ATGAAAATAAAACCACCACTCTGGCTGTGCGTGCTGTTGATGATGTTTCCGCAAATTATGGAAACCATCTATAGCCCGGC
TTTGCCAAATATTGCAGAAAACTTTGCGGTGTCTGTTACCAGCGCCTCGCAAACCTTATCCGTGTACTTCATCGCCTTTG
CTGTAGGCGTATTTTGCTGGGGTCGTTTAGCTGACATTATTGGTCGCCGTAACGCCATGCTTGCGGGCTTAGTCTGTTAT
GCCATTGGTTCAGCCTTCGCGTTGATGATTAGCGACTTTACTCTGCTGTTGCTGGCGCGCATATTATCGGCCTTTGGTGC
CGCGGTTGGCTCTGTCATTACTCAAACCATGATGCGTGACAGTTACAGCGGGGAGGAATTGGCCAAAGTCTTTTCGGTGA
TGGGCATGTCTCTTGGGATCAGCCCGATTATCGGATTGCTATTGGGGAGTCTCCTCAGTGCTTATTGGGGATATCAAGGT
GTGTTTGTCGCCCTGATGGTTTCTGCCATAGTGTTGTTGTTTTTGTCGTTAAAATCTTTGCCCGAAACGAGGCCTGCACA
TACCCAAAAAATCGCGATAGTTGAGTTAGCTATCAAGATGCTTACCGACAGTGGGATAATTAAAAACACCTTGCTGGTGG
CCTCATTTAACTTGATGTGGTTTAGCTACTTTTCATTGGCGCCATTTATGTTTGAGGCGCAAGGATTGTCGACGCTTGCC
TTCGGGATGAGTGGGTTGTTATTGGGCCTTGGCGCATTCCTTGGCAGTTATTTTAATAAACTATTACTAGGCAGAGGTTA
CTCCAGTGCACTATTAGTGCGGTTAGCAAGCCTTATTGCACTATTCGGAGGACTTGGTATTTGGCTGTTCCAATCGACAG
ATATTGGCTTGGATAATGTTTACTTCTTACTACCCATGCTGTTGATTGTGATTGCTTATGGGATAGCGATTCCGAACATA
CTCAGTTCGGCGCTGGCAAACTACCGCGCTTATGCTGGTTCTGCTGGCGCGCTGTTTGGACTGTTTTATTACATTCTGTT
GGGGCTAGGTTTAGGCGCTGCAGGCATGGTTAGCCATCTTGGGGGCGTGATTAGCTTCGCGGCGCTGCTTTGTGTGGGGC
TTGGTTTGACGAGCTTGACTAACTTGAAGAGCTTGACTGGGCGAAGAGGGAGCGGTTCTCAGACTTAA

Upstream 100 bases:

>100_bases
CACTTGGGGATCCTATCTATACTGCGCCCTCTTTGACAAGTATGGAGCGCCGTTTTGGTTTATCGGTTAACACTGAAAGG
CTAAAACGCAGATAAAAATC

Downstream 100 bases:

>100_bases
ATAAAAAAGCCAAGGGGCAATGAGTCCCTTGGCTTTATGATTTTAACAAACACCTTATGCCGTTTCGCTTTACTGTATCG
CGCTAGGCTTTGGCTGTTTG

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLVCY
AIGSAFALMISDFTLLLLARILSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPIIGLLLGSLLSAYWGYQG
VFVALMVSAIVLLFLSLKSLPETRPAHTQKIAIVELAIKMLTDSGIIKNTLLVASFNLMWFSYFSLAPFMFEAQGLSTLA
FGMSGLLLGLGAFLGSYFNKLLLGRGYSSALLVRLASLIALFGGLGIWLFQSTDIGLDNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGAAGMVSHLGGVISFAALLCVGLGLTSLTNLKSLTGRRGSGSQT

Sequences:

>Translated_395_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLVCY
AIGSAFALMISDFTLLLLARILSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPIIGLLLGSLLSAYWGYQG
VFVALMVSAIVLLFLSLKSLPETRPAHTQKIAIVELAIKMLTDSGIIKNTLLVASFNLMWFSYFSLAPFMFEAQGLSTLA
FGMSGLLLGLGAFLGSYFNKLLLGRGYSSALLVRLASLIALFGGLGIWLFQSTDIGLDNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGAAGMVSHLGGVISFAALLCVGLGLTSLTNLKSLTGRRGSGSQT
>Mature_395_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLVCY
AIGSAFALMISDFTLLLLARILSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPIIGLLLGSLLSAYWGYQG
VFVALMVSAIVLLFLSLKSLPETRPAHTQKIAIVELAIKMLTDSGIIKNTLLVASFNLMWFSYFSLAPFMFEAQGLSTLA
FGMSGLLLGLGAFLGSYFNKLLLGRGYSSALLVRLASLIALFGGLGIWLFQSTDIGLDNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGAAGMVSHLGGVISFAALLCVGLGLTSLTNLKSLTGRRGSGSQT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=318, Percent_Identity=26.1006289308176, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082312, Length=327, Percent_Identity=26.9113149847095, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788509, Length=187, Percent_Identity=28.3422459893048, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790146, Length=175, Percent_Identity=30.8571428571429, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41983; Mature: 41983

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA