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The map label for this gene is foxA [H]

Identifier: 113969323

GI number: 113969323

Start: 1145944

End: 1148118

Strand: Direct

Name: foxA [H]

Synonym: Shewmr4_0979

Alternate gene names: 113969323

Gene position: 1145944-1148118 (Clockwise)

Preceding gene: 113969322

Following gene: 113969324

Centisome position: 24.35

GC content: 49.93

Gene sequence:

>2175_bases
ATGCTGTTTATTTTTGGAGTGAAAATGGCTGTTTATGTGAGCCACAAGCGCTCGGCATTAGTGCTGGGCGTGGCGTTATT
GGCGTTGGATGCGAGTGTTCCCCTATTGGCCGCCGAGGCTGTGCCAACTGATACCGCCGGACTTAATGACGACGATATCG
AGCGTTTAAGCATTCATTATCGTCAGGCCTACCGCGGCAATGTGCCGGCGACTGAGTTACCCCAAGCGATTACTGTGCTG
GATGAGCAACTGATTAAAGATACTGGGCTGACGCGTTTTCAAGACTTATTGGATTACTCCGCCAGTGTCGCGCGGCAAAA
CAACGGTGGTGGGCTGTGGGATAGTTTTTCGTTACGGGGCTTTCCTGGGAATGAAAACATGCCATCGGGCTATTTAATCA
ATGGTTTTAATGGTGGCCGAGGATTCAGTGGTCATAGAGATCTATCGAACGTGGCCTATGTGGAAATCCTCAAAGGCCCG
GGTTCGGCGCTTTATGGACGCTCGGAGCCGGGTGGCACAGTGAATATTGTGACTAAAAAGCCGCAGTACGAGGCGCAAGG
CTATTTAAAAGCGTCTGCGGGGAGTTTCGATCAATATCGGTTGGAAGGGGATTTTACCTCGGGGCTGACCGATACCTTGG
CCTTTAGGATCAATGGCGCTTGGCAGGAGCATGACAGTTTTCGCGATTACGTGTTTAGCGATAAAAAGATCGTCACGCCA
TCGCTGCGCTGGCAACTGTCCGATAAGTCATCGCTCCTGTATGAGGTTGAATATCTTAAGCAAGAACAGTTATTTGACCG
TGGTGTAGTGGTACTCAATAACGACTTTAATACCGTGCCCCGTTCGCGTTACTTGGGCGAGCCCAACGATGGGCCAACTA
AAGTGGATGCGACTGGGCATCAACTTACCTATGAGTATGAATTAAATGAGGATTGGTCGCTTACCGCGGGTTATAACTAT
CGCGATTCGAGTCTGAATGGCTACTCATCGGATGCAGAATTAGCAAAGGGACGTCAATCCTTATATGACGATGGCCGTAC
TCTGACGCGGCAACATCGCTATCGAGATTACGCCTCAGAGGATCATTCAGTACGTGCCGAACTCAGTGGCCAGTTTGATA
CCGGCAGCATAAGACACAATCTGCTGCTCGGGACGGATGCCTATCATTATCGACTAAAAACGGGACTCTACCGTTATCGA
GGCCAGAAGGGCGCCTATGCCATCGATATTTTTACCCCCCAATATGGCGCGGCTCAGCCAGAGGTCAGTCTGCTGTATGA
AAACCGAGAGACTCAAGATGCCTGGGGCGCCTATTTACAGGATCAATTGGAGTTAACCGAGCACTGGAAACTGCATTTAG
GGTTAAGGTTTGACCGTTATTCCCAAGAAATCGCAGAGCAGGTCAACGCGAGTCTGTCGGATCAAAGCGATAACAGAGTC
AGTCCGAAAGTCGGATTAGTGTATCAATGGTCTGAGGCCTTAAGTGTTTACGGCTCCTATTCGGAAGGATTCTTACCGCT
TTCAGGCACTGATTATGCGGGTAATCCCTTCGAGCCAGAGGAGAGCAAATCCGTCGAGTTAGGGGTTAAGTTCAACAGCA
CTTGGTTTGAGCTACCCGTCAATGGCAGTTTGGCTTGGTTTGATGCGCAAAAGAGCAATATCTTGACCTCAGATCCCGTC
AATGTCGGCTTTTCGGCGACCCTTGGTGAAGCCAAGAGCACGGGGATTGAATTGGATATCGCGGCTGAATTGACCGAGAG
CTTACAAGCGACCTTGTCCTATGCCTACCTGAATACCCGCACGGCGAACGACAGTCTGAATCTAGATTGGGGCGTGTTAA
TTCCGGCGGGAAGTCCGCTGGTCAATGTGCCAAAACACACGGGCAGTATCATTCTCAAACAGGACTTAAATGATCTATCT
ATCGACGGTCATTTAGGGCTGAGTTGGCGTTATGTGGACTCTCGCTTGGGCGATTCGGCCGATCCGAGTTTTCAATTACC
GAGTTATCAGTTGCTTGGAATGTTCTTCACTACTCGGCTTGGCGAAAACCTAAGTCTTGCGCTCAATGTCGATAACCTGC
TGGATGAGCATTATATCGCCAGCAGTTATTCGGCGCTGTGGGCCGTGCCGGGTGAGCCACGTAACGTTAAAGTGAGTGTT
AGCTATGAATTCTAA

Upstream 100 bases:

>100_bases
GCGCCACTTCCATAGCCGCGCGCCGCCGCTAACAGCCTAACTCCTGCTTTTTATCTATTTCTCTTATTTTTCGAGCGCCT
TAGCTTAACTAAGGTGCCCG

Downstream 100 bases:

>100_bases
TGCCATTGTGACACCCGCCGCTTCGCCTGAGACGCTTCAGCTGCAAGGGCGTCAGCGGATCAATAGCATCGACATGATGC
GCGGCTTAGTGATGTTGATT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MLFIFGVKMAVYVSHKRSALVLGVALLALDASVPLLAAEAVPTDTAGLNDDDIERLSIHYRQAYRGNVPATELPQAITVL
DEQLIKDTGLTRFQDLLDYSASVARQNNGGGLWDSFSLRGFPGNENMPSGYLINGFNGGRGFSGHRDLSNVAYVEILKGP
GSALYGRSEPGGTVNIVTKKPQYEAQGYLKASAGSFDQYRLEGDFTSGLTDTLAFRINGAWQEHDSFRDYVFSDKKIVTP
SLRWQLSDKSSLLYEVEYLKQEQLFDRGVVVLNNDFNTVPRSRYLGEPNDGPTKVDATGHQLTYEYELNEDWSLTAGYNY
RDSSLNGYSSDAELAKGRQSLYDDGRTLTRQHRYRDYASEDHSVRAELSGQFDTGSIRHNLLLGTDAYHYRLKTGLYRYR
GQKGAYAIDIFTPQYGAAQPEVSLLYENRETQDAWGAYLQDQLELTEHWKLHLGLRFDRYSQEIAEQVNASLSDQSDNRV
SPKVGLVYQWSEALSVYGSYSEGFLPLSGTDYAGNPFEPEESKSVELGVKFNSTWFELPVNGSLAWFDAQKSNILTSDPV
NVGFSATLGEAKSTGIELDIAAELTESLQATLSYAYLNTRTANDSLNLDWGVLIPAGSPLVNVPKHTGSIILKQDLNDLS
IDGHLGLSWRYVDSRLGDSADPSFQLPSYQLLGMFFTTRLGENLSLALNVDNLLDEHYIASSYSALWAVPGEPRNVKVSV
SYEF

Sequences:

>Translated_724_residues
MLFIFGVKMAVYVSHKRSALVLGVALLALDASVPLLAAEAVPTDTAGLNDDDIERLSIHYRQAYRGNVPATELPQAITVL
DEQLIKDTGLTRFQDLLDYSASVARQNNGGGLWDSFSLRGFPGNENMPSGYLINGFNGGRGFSGHRDLSNVAYVEILKGP
GSALYGRSEPGGTVNIVTKKPQYEAQGYLKASAGSFDQYRLEGDFTSGLTDTLAFRINGAWQEHDSFRDYVFSDKKIVTP
SLRWQLSDKSSLLYEVEYLKQEQLFDRGVVVLNNDFNTVPRSRYLGEPNDGPTKVDATGHQLTYEYELNEDWSLTAGYNY
RDSSLNGYSSDAELAKGRQSLYDDGRTLTRQHRYRDYASEDHSVRAELSGQFDTGSIRHNLLLGTDAYHYRLKTGLYRYR
GQKGAYAIDIFTPQYGAAQPEVSLLYENRETQDAWGAYLQDQLELTEHWKLHLGLRFDRYSQEIAEQVNASLSDQSDNRV
SPKVGLVYQWSEALSVYGSYSEGFLPLSGTDYAGNPFEPEESKSVELGVKFNSTWFELPVNGSLAWFDAQKSNILTSDPV
NVGFSATLGEAKSTGIELDIAAELTESLQATLSYAYLNTRTANDSLNLDWGVLIPAGSPLVNVPKHTGSIILKQDLNDLS
IDGHLGLSWRYVDSRLGDSADPSFQLPSYQLLGMFFTTRLGENLSLALNVDNLLDEHYIASSYSALWAVPGEPRNVKVSV
SYEF
>Mature_724_residues
MLFIFGVKMAVYVSHKRSALVLGVALLALDASVPLLAAEAVPTDTAGLNDDDIERLSIHYRQAYRGNVPATELPQAITVL
DEQLIKDTGLTRFQDLLDYSASVARQNNGGGLWDSFSLRGFPGNENMPSGYLINGFNGGRGFSGHRDLSNVAYVEILKGP
GSALYGRSEPGGTVNIVTKKPQYEAQGYLKASAGSFDQYRLEGDFTSGLTDTLAFRINGAWQEHDSFRDYVFSDKKIVTP
SLRWQLSDKSSLLYEVEYLKQEQLFDRGVVVLNNDFNTVPRSRYLGEPNDGPTKVDATGHQLTYEYELNEDWSLTAGYNY
RDSSLNGYSSDAELAKGRQSLYDDGRTLTRQHRYRDYASEDHSVRAELSGQFDTGSIRHNLLLGTDAYHYRLKTGLYRYR
GQKGAYAIDIFTPQYGAAQPEVSLLYENRETQDAWGAYLQDQLELTEHWKLHLGLRFDRYSQEIAEQVNASLSDQSDNRV
SPKVGLVYQWSEALSVYGSYSEGFLPLSGTDYAGNPFEPEESKSVELGVKFNSTWFELPVNGSLAWFDAQKSNILTSDPV
NVGFSATLGEAKSTGIELDIAAELTESLQATLSYAYLNTRTANDSLNLDWGVLIPAGSPLVNVPKHTGSIILKQDLNDLS
IDGHLGLSWRYVDSRLGDSADPSFQLPSYQLLGMFFTTRLGENLSLALNVDNLLDEHYIASSYSALWAVPGEPRNVKVSV
SYEF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=709, Percent_Identity=24.9647390691114, Blast_Score=178, Evalue=9e-46,
Organism=Escherichia coli, GI1787024, Length=732, Percent_Identity=23.6338797814208, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787344, Length=302, Percent_Identity=24.5033112582781, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80462; Mature: 80462

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIFGVKMAVYVSHKRSALVLGVALLALDASVPLLAAEAVPTDTAGLNDDDIERLSIHY
CEEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
RQAYRGNVPATELPQAITVLDEQLIKDTGLTRFQDLLDYSASVARQNNGGGLWDSFSLRG
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCCCEECC
FPGNENMPSGYLINGFNGGRGFSGHRDLSNVAYVEILKGPGSALYGRSEPGGTVNIVTKK
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEECCCCCCCCEEEEEECC
PQYEAQGYLKASAGSFDQYRLEGDFTSGLTDTLAFRINGAWQEHDSFRDYVFSDKKIVTP
CCCCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEEECCCHHCCCCHHHHHCCCCEEECC
SLRWQLSDKSSLLYEVEYLKQEQLFDRGVVVLNNDFNTVPRSRYLGEPNDGPTKVDATGH
CEEEEECCCCCEEEHHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCCCCCCCEEEECCCC
QLTYEYELNEDWSLTAGYNYRDSSLNGYSSDAELAKGRQSLYDDGRTLTRQHRYRDYASE
EEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
DHSVRAELSGQFDTGSIRHNLLLGTDAYHYRLKTGLYRYRGQKGAYAIDIFTPQYGAAQP
CCEEEEEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCC
EVSLLYENRETQDAWGAYLQDQLELTEHWKLHLGLRFDRYSQEIAEQVNASLSDQSDNRV
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCC
SPKVGLVYQWSEALSVYGSYSEGFLPLSGTDYAGNPFEPEESKSVELGVKFNSTWFELPV
CCCEEEEEEECHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEC
NGSLAWFDAQKSNILTSDPVNVGFSATLGEAKSTGIELDIAAELTESLQATLSYAYLNTR
CCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHEEEEEEEEE
TANDSLNLDWGVLIPAGSPLVNVPKHTGSIILKQDLNDLSIDGHLGLSWRYVDSRLGDSA
CCCCCCCCCEEEEEECCCCCEECCCCCCCEEEEECCCCEEECCCCCEEEEEEHHHCCCCC
DPSFQLPSYQLLGMFFTTRLGENLSLALNVDNLLDEHYIASSYSALWAVPGEPRNVKVSV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
SYEF
EECC
>Mature Secondary Structure
MLFIFGVKMAVYVSHKRSALVLGVALLALDASVPLLAAEAVPTDTAGLNDDDIERLSIHY
CEEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
RQAYRGNVPATELPQAITVLDEQLIKDTGLTRFQDLLDYSASVARQNNGGGLWDSFSLRG
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCCCEECC
FPGNENMPSGYLINGFNGGRGFSGHRDLSNVAYVEILKGPGSALYGRSEPGGTVNIVTKK
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEECCCCCCCCEEEEEECC
PQYEAQGYLKASAGSFDQYRLEGDFTSGLTDTLAFRINGAWQEHDSFRDYVFSDKKIVTP
CCCCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEEECCCHHCCCCHHHHHCCCCEEECC
SLRWQLSDKSSLLYEVEYLKQEQLFDRGVVVLNNDFNTVPRSRYLGEPNDGPTKVDATGH
CEEEEECCCCCEEEHHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCCCCCCCEEEECCCC
QLTYEYELNEDWSLTAGYNYRDSSLNGYSSDAELAKGRQSLYDDGRTLTRQHRYRDYASE
EEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
DHSVRAELSGQFDTGSIRHNLLLGTDAYHYRLKTGLYRYRGQKGAYAIDIFTPQYGAAQP
CCEEEEEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCC
EVSLLYENRETQDAWGAYLQDQLELTEHWKLHLGLRFDRYSQEIAEQVNASLSDQSDNRV
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCC
SPKVGLVYQWSEALSVYGSYSEGFLPLSGTDYAGNPFEPEESKSVELGVKFNSTWFELPV
CCCEEEEEEECHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEC
NGSLAWFDAQKSNILTSDPVNVGFSATLGEAKSTGIELDIAAELTESLQATLSYAYLNTR
CCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHEEEEEEEEE
TANDSLNLDWGVLIPAGSPLVNVPKHTGSIILKQDLNDLSIDGHLGLSWRYVDSRLGDSA
CCCCCCCCCEEEEEECCCCCEECCCCCCCEEEEECCCCEEECCCCCEEEEEEHHHCCCCC
DPSFQLPSYQLLGMFFTTRLGENLSLALNVDNLLDEHYIASSYSALWAVPGEPRNVKVSV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
SYEF
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]