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The map label for this gene is hlyB [H]

Identifier: 113969290

GI number: 113969290

Start: 1102894

End: 1104897

Strand: Direct

Name: hlyB [H]

Synonym: Shewmr4_0946

Alternate gene names: 113969290

Gene position: 1102894-1104897 (Clockwise)

Preceding gene: 113969289

Following gene: 113969291

Centisome position: 23.43

GC content: 50.05

Gene sequence:

>2004_bases
ATGAGATATATAAAACGTTCTCTTAGTTTGCAGTTAGTGGTAACTATCGTCGGTGCCCTCGCTGTACTTCTTACTTTAGT
TGCCGCTTTGCTCGTGAATAAAGAAAGTAATAACACACGTAAGCAAGTCGATGCGGACATTTCGGCGCTTGTGGCTCTCA
AGGCCAATGAGATAGGTGGTTATTTTGTTGCTAAAGGGCAAGTGATCCACTCGGTTTTTGCCGAGCCTGGGCTTATCCAT
TGGTTTAGCCAATATCATGCCCGTGGCAGTAACTTAGCCAACGATCAACAGTACCAAGATATTATTCGCTATTTCCGCTC
GTTCTCCGACCGTGATAGCGATGTGAAGTCAGTGTTCTTTGGCTCGGCGAATACCTTCGAGTATTTCGATCTCAATGGCC
GTTTCGATGGCGATCCAAACTATTACACTAACAAGCGTCCTTGGTGGCAGGAGGCTATCGATCAGCGCAGCTTGTTTGTG
GGCGATCCTGCGGTCGATGCCAACGATGGATCTATTTCGGCCACGGTTAAAACCCCAGTCTATGGTGCCAATGGTGAACT
CATCGGCATTGGTGGTATGGATATTCTTATCGATACCATTGGTAAAACCCTGTTAGCGCCAATCAAATACCGCAACTATG
GCCAAGCCTTCTTGATGACAGATGAAGGTAAGCTGGTTTATTTCCCAGGTTTCTCTGATAAATTCCCGCCGGGCTCACTT
GCGAATCAAATCGATAGCCAGTTTAAGGACACCTCAGGTTTTTCCGCCTTAAGACAACAAATGCAGCGCGAGACGCAGGG
CTTTGCCGAAGTCACCTTTAACGGTGTGCCGCAGCGGGTAACCTTCGTGTCTGTGGGCGGTGATTATCCTAAGCAAAAAT
GGCATTTAGCCTTTATGTTGCCCCATGAGGTGATTGAAGCGCCTGTAACCGAAGCCTTTTGGAATGCCTGTTTTGTTGCC
TTAGGGATTATGTTGTTGGTCGGCATCACAGTATGGTTGATGTTATTGCCCTTTAGACGCCAGCTCAGCAAATTGCTCGA
TGCGATGGAAGACATTGCCGAAGGTGATAGCGATTTATCCCAACGCATTTTAATGGAGCGCGAAGATGAGTTAGGCAAGT
TGGGTGATGCCTTCAATCGCTTTGCCGAAAAGGTGCAGCAGATGTTACTGCACACTCGCAACTTAACCCAAGAGGTGGGC
ACTGGGGTGATGGATGCGCGCCAAGTGTGTGATTTAGCGGTATCTTCGGTGTCATCGCAAAAACAACAAATCGACTCAGT
GGCCACGGCCGCCACCCAAATGGCACAGACGAGCCAAGAAATGGCGATAAGCGCTCAGCGAGCGAATGATTTTGCTGAAA
AGGCACAGACTCAGGCCCATGACGGTACCCAAATCGTGTCCCGTGCGACCGAAGGCATGAAGGCATTATCGGTTCAAGTG
ATTGAAGCGGCCAAAGTCATCAAGGAGTTACGTAGCAGCTCCGAGCAAATTGGCGAAGTGTTAAGTGTGATCCGCAACAT
TGCCGACCAAACCAACTTGCTGGCGCTCAATGCGGCCATCGAGGCGGCGCGGGCGGGTGAGCAGGGCCGAGGCTTTGCCG
TGGTGGCCGATGAAGTGCGTACCCTCGCGTCTCGTACCCAAGATTCTACCGCCAACATTCAAGGGATTATCCAAACCCTG
CAACAGAGTGCGCTACAAGCCGAGCAGGTGATGGAATCTGGGGTTGAGCAGGCAAAAGTCGGGCAAGACTTGACCACACA
AGTGGAGCAAGCCTTAAGTGATATCGCCAGTGCCATTGTGTCGATTCAGCAGCAAACGGTGGAAATTACCGTCGCGATTG
GCCAGCAGGCCGTTGTGGCAGAAGAAGTGGCACAGAACGTGGTTAGCGTGCGTGGTTTGTCCGATCAGTCTTTGCTCTCG
AGCCAAGATTTATCCCAAAGTTTGCAAGGATTTGAGCAAGCGACTCACGAACTCACCCGCAACATTGGGCAATTTAAGAT
TTAA

Upstream 100 bases:

>100_bases
CATCATTTCGGCTGTTGTTGGCTGGTAAAAATTGTTACCGTGTGAAACTGTTTTTGCAGGCTTTTTTGTTAAGTGGTTGG
TTAACCAGACGGGAAGATGG

Downstream 100 bases:

>100_bases
TTCAAAACGTTGCAAATCAAGGGAGCCTTAGGGCTCCCTTTGTTTTTTGAGCGCTGACAATCCAAGCGCAAACAGCACCG
CGGCAAATTGATAAGTGGCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MRYIKRSLSLQLVVTIVGALAVLLTLVAALLVNKESNNTRKQVDADISALVALKANEIGGYFVAKGQVIHSVFAEPGLIH
WFSQYHARGSNLANDQQYQDIIRYFRSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPNYYTNKRPWWQEAIDQRSLFV
GDPAVDANDGSISATVKTPVYGANGELIGIGGMDILIDTIGKTLLAPIKYRNYGQAFLMTDEGKLVYFPGFSDKFPPGSL
ANQIDSQFKDTSGFSALRQQMQRETQGFAEVTFNGVPQRVTFVSVGGDYPKQKWHLAFMLPHEVIEAPVTEAFWNACFVA
LGIMLLVGITVWLMLLPFRRQLSKLLDAMEDIAEGDSDLSQRILMEREDELGKLGDAFNRFAEKVQQMLLHTRNLTQEVG
TGVMDARQVCDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAISAQRANDFAEKAQTQAHDGTQIVSRATEGMKALSVQV
IEAAKVIKELRSSSEQIGEVLSVIRNIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTL
QQSALQAEQVMESGVEQAKVGQDLTTQVEQALSDIASAIVSIQQQTVEITVAIGQQAVVAEEVAQNVVSVRGLSDQSLLS
SQDLSQSLQGFEQATHELTRNIGQFKI

Sequences:

>Translated_667_residues
MRYIKRSLSLQLVVTIVGALAVLLTLVAALLVNKESNNTRKQVDADISALVALKANEIGGYFVAKGQVIHSVFAEPGLIH
WFSQYHARGSNLANDQQYQDIIRYFRSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPNYYTNKRPWWQEAIDQRSLFV
GDPAVDANDGSISATVKTPVYGANGELIGIGGMDILIDTIGKTLLAPIKYRNYGQAFLMTDEGKLVYFPGFSDKFPPGSL
ANQIDSQFKDTSGFSALRQQMQRETQGFAEVTFNGVPQRVTFVSVGGDYPKQKWHLAFMLPHEVIEAPVTEAFWNACFVA
LGIMLLVGITVWLMLLPFRRQLSKLLDAMEDIAEGDSDLSQRILMEREDELGKLGDAFNRFAEKVQQMLLHTRNLTQEVG
TGVMDARQVCDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAISAQRANDFAEKAQTQAHDGTQIVSRATEGMKALSVQV
IEAAKVIKELRSSSEQIGEVLSVIRNIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTL
QQSALQAEQVMESGVEQAKVGQDLTTQVEQALSDIASAIVSIQQQTVEITVAIGQQAVVAEEVAQNVVSVRGLSDQSLLS
SQDLSQSLQGFEQATHELTRNIGQFKI
>Mature_667_residues
MRYIKRSLSLQLVVTIVGALAVLLTLVAALLVNKESNNTRKQVDADISALVALKANEIGGYFVAKGQVIHSVFAEPGLIH
WFSQYHARGSNLANDQQYQDIIRYFRSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPNYYTNKRPWWQEAIDQRSLFV
GDPAVDANDGSISATVKTPVYGANGELIGIGGMDILIDTIGKTLLAPIKYRNYGQAFLMTDEGKLVYFPGFSDKFPPGSL
ANQIDSQFKDTSGFSALRQQMQRETQGFAEVTFNGVPQRVTFVSVGGDYPKQKWHLAFMLPHEVIEAPVTEAFWNACFVA
LGIMLLVGITVWLMLLPFRRQLSKLLDAMEDIAEGDSDLSQRILMEREDELGKLGDAFNRFAEKVQQMLLHTRNLTQEVG
TGVMDARQVCDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAISAQRANDFAEKAQTQAHDGTQIVSRATEGMKALSVQV
IEAAKVIKELRSSSEQIGEVLSVIRNIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTL
QQSALQAEQVMESGVEQAKVGQDLTTQVEQALSDIASAIVSIQQQTVEITVAIGQQAVVAEEVAQNVVSVRGLSDQSLLS
SQDLSQSLQGFEQATHELTRNIGQFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=366, Percent_Identity=30.327868852459, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI2367378, Length=395, Percent_Identity=25.8227848101266, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1788195, Length=328, Percent_Identity=28.6585365853659, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=347, Percent_Identity=28.5302593659942, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789453, Length=330, Percent_Identity=29.0909090909091, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73060; Mature: 73060

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYIKRSLSLQLVVTIVGALAVLLTLVAALLVNKESNNTRKQVDADISALVALKANEIGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCC
YFVAKGQVIHSVFAEPGLIHWFSQYHARGSNLANDQQYQDIIRYFRSFSDRDSDVKSVFF
EEEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHC
GSANTFEYFDLNGRFDGDPNYYTNKRPWWQEAIDQRSLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCE
YGANGELIGIGGMDILIDTIGKTLLAPIKYRNYGQAFLMTDEGKLVYFPGFSDKFPPGSL
ECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCHH
ANQIDSQFKDTSGFSALRQQMQRETQGFAEVTFNGVPQRVTFVSVGGDYPKQKWHLAFML
HHHHHHHHCCCCCHHHHHHHHHHHHCCHHHEEECCCCCEEEEEEECCCCCCCCEEEEEEC
PHEVIEAPVTEAFWNACFVALGIMLLVGITVWLMLLPFRRQLSKLLDAMEDIAEGDSDLS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QRILMEREDELGKLGDAFNRFAEKVQQMLLHTRNLTQEVGTGVMDARQVCDLAVSSVSSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KQQIDSVATAATQMAQTSQEMAISAQRANDFAEKAQTQAHDGTQIVSRATEGMKALSVQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IEAAKVIKELRSSSEQIGEVLSVIRNIADQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHHH
TLASRTQDSTANIQGIIQTLQQSALQAEQVMESGVEQAKVGQDLTTQVEQALSDIASAIV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHH
SIQQQTVEITVAIGQQAVVAEEVAQNVVSVRGLSDQSLLSSQDLSQSLQGFEQATHELTR
HHHHHHEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGQFKI
HHCCCCC
>Mature Secondary Structure
MRYIKRSLSLQLVVTIVGALAVLLTLVAALLVNKESNNTRKQVDADISALVALKANEIGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCC
YFVAKGQVIHSVFAEPGLIHWFSQYHARGSNLANDQQYQDIIRYFRSFSDRDSDVKSVFF
EEEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHC
GSANTFEYFDLNGRFDGDPNYYTNKRPWWQEAIDQRSLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCE
YGANGELIGIGGMDILIDTIGKTLLAPIKYRNYGQAFLMTDEGKLVYFPGFSDKFPPGSL
ECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCHH
ANQIDSQFKDTSGFSALRQQMQRETQGFAEVTFNGVPQRVTFVSVGGDYPKQKWHLAFML
HHHHHHHHCCCCCHHHHHHHHHHHHCCHHHEEECCCCCEEEEEEECCCCCCCCEEEEEEC
PHEVIEAPVTEAFWNACFVALGIMLLVGITVWLMLLPFRRQLSKLLDAMEDIAEGDSDLS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QRILMEREDELGKLGDAFNRFAEKVQQMLLHTRNLTQEVGTGVMDARQVCDLAVSSVSSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KQQIDSVATAATQMAQTSQEMAISAQRANDFAEKAQTQAHDGTQIVSRATEGMKALSVQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IEAAKVIKELRSSSEQIGEVLSVIRNIADQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHHH
TLASRTQDSTANIQGIIQTLQQSALQAEQVMESGVEQAKVGQDLTTQVEQALSDIASAIV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHH
SIQQQTVEITVAIGQQAVVAEEVAQNVVSVRGLSDQSLLSSQDLSQSLQGFEQATHELTR
HHHHHHEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGQFKI
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]