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The map label for this gene is apbE [H]

Identifier: 113969286

GI number: 113969286

Start: 1099909

End: 1101033

Strand: Direct

Name: apbE [H]

Synonym: Shewmr4_0942

Alternate gene names: 113969286

Gene position: 1099909-1101033 (Clockwise)

Preceding gene: 113969285

Following gene: 113969287

Centisome position: 23.37

GC content: 46.4

Gene sequence:

>1125_bases
ATGTGGAGTAAAGCTCTCATCTGCAACTTTTGTATTAAAGGGCATCCAAAAGAGTTGTTAGTCACTATGTTTAAAACCCT
AGCGTTAAAAACCCCCGTGTTAAAAACCTCAGTGTTAAAGCATTCAGTGAACTGGCTGGTCCTTGTAGGTCTAGCCTTTT
TTATTTCAGCCTGTAGCAAACAGGATGAGGTTATCTCCCTCGCGGGCAGCACAATGGGCACGACCTACCACATTAAAGTG
GTTCCCAATGAGCAAATGCCAACGGCCCAGCTGTTGCAGGCCGAAATTGACTTAGCCCTAGAGCAAGTCAATAACCAGAT
GTCGACTTATCGACCCAATTCAGAACTGTCTCGTTTCAATCAGTTACCGCTCGAGCAAAGCGTTGAAGTGTCGCCGGATA
CCATTAAAGTGGTTAAAGAAGGCATGCGTTTGTATAACGTGACGGACAAAGCCTTAGACATTACCTTAGGGCCGCTGGTG
AACCTATGGGGATTTGGCCCCGATAAACGCCCAACCAAAGTGCCAACTCAAGCCGATATCGATGCGGCTAAAGCCAAAAC
GGGTATCAGTGAGCTTTCTATCGAAGGCAATCGCTTAAGCAAGCACAATGCGCATTTATATGTGGACTTGTCTTCAATCG
CCAAAGGTTTTGGCGTGGACAAAGTGGCCTCGATTTTAGATAAGTACCATGCAAGCGGTTACTTAGTCGAAATTGGTGGC
GAGCTGAGCATTAAAGGCACTAAAGGCGATGGTAGCTCATGGCGCGTCGCGATAGAGAAACCGACCGATGATGGCATGGC
GGTGCAACAGGTGATTGAGCCTGGCACTATGGCGATGGCAACGTCGGGGGATTATCGCAATTATTATGAGGAAGAAGGTC
AGCGTTTTACTCATATAATTGATCCACGTACCGGTTTACCTATTAATCATAAGCTAGCATCTGTGACCGTTTTGCATAAA
GAATGTATGACGGCCGATGGTTTTGCGACGGCGATGATGGTTTTAGGCACAGAAGCGTCATTGGAGCTTGCCAAGAAAGA
ACACTTGGCGATAATGCTAATAGAAAAGCAAGGCGAAGGATTTAAAGTCTACTACAGTGACGCCTTCAAGCCTTTCCTTA
AGTAG

Upstream 100 bases:

>100_bases
TAATCGGTATGTTGAAAAATCTTGGTGTCGAAGACGAAAACATCCTGTTGGATGACTTCGGCGGCTAATGTGAATTAGCC
CAAGGTGAGAAGAGTTGCAG

Downstream 100 bases:

>100_bases
TTGGAGTTAACATGAGCACTTTTATCGCGGCATTTGTGATTTTATTACTGTTCTTTTTGCTTATGTCGATAGGTTATCTC
ATCAAGCGCAAAGCCGTTGA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MWSKALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVNWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
ECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK

Sequences:

>Translated_374_residues
MWSKALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVNWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
ECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK
>Mature_374_residues
MWSKALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVNWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
ECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=344, Percent_Identity=40.406976744186, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 41138; Mature: 41138

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSKALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVNWLVLVGLAFFISACSK
CCCCCEEHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QDEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFN
CCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLVNLWGFGPDKRPTKVPTQADI
CCCCCCCCCCCCHHHHHHHHCHHEEECCCHHHEEEHHHHHHHHCCCCCCCCCCCCCCCCC
DAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
HHHHHHCCHHHEEECCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHII
EEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEEE
DPRTGLPINHKLASVTVLHKECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEG
CCCCCCCCCCHHHHEEEHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCC
FKVYYSDAFKPFLK
EEEEECCCCHHHCC
>Mature Secondary Structure
MWSKALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVNWLVLVGLAFFISACSK
CCCCCEEHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QDEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFN
CCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLVNLWGFGPDKRPTKVPTQADI
CCCCCCCCCCCCHHHHHHHHCHHEEECCCHHHEEEHHHHHHHHCCCCCCCCCCCCCCCCC
DAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
HHHHHHCCHHHEEECCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHII
EEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEEE
DPRTGLPINHKLASVTVLHKECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEG
CCCCCCCCCCHHHHEEEHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCC
FKVYYSDAFKPFLK
EEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]