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The map label for this gene is yjcC [H]

Identifier: 113969113

GI number: 113969113

Start: 894202

End: 896217

Strand: Direct

Name: yjcC [H]

Synonym: Shewmr4_0769

Alternate gene names: 113969113

Gene position: 894202-896217 (Clockwise)

Preceding gene: 113969112

Following gene: 113969114

Centisome position: 19.0

GC content: 44.39

Gene sequence:

>2016_bases
ATGAAGTTTGAGCTACGTCAATTTCTCGATAGAAGCTTTCTTATCTCGATACGTGAATCCTTTATCGCGTTACTGCCTTT
TATTTTAATCAATTCTTTTCTCTCCCTGATAATTACATTGCTCGACCTTAGTATTCCGGCTTGGCAGAGCACTGCATTTC
ATCAGAGTATTAGTTTCTTTTCGGTACAACTTTCAAAAATTTTCCCGTTACTTGCGCTGATTTCTCTGTCTTTTCACTTT
GCTAAATATTTACAGTTATCGGCGATTGTGGTGTGTTCTTTGTCGCTGAGTCTTTTGCTCGCGATTAATGCCCAAGATAC
GGGGAATGTATTTAATCTCGATTATGTGCGCGCTATTTTAGCGGATCCTAGGATTGCGGTTTTACCGATTATTTCAGCCT
ATTTATTACGATTTTTAACCGCTTGGAACGGATTAACCTTTATTAGGGCAAAGGCTCTTAGCCGTTACTTAAAGCTGCAC
TTAAACTTATTTTTCCCCATAGTAATCGGCTTTATTGGCCTGTTCGCCATCGTTGCTGAAGCCTCTATCTTTTTAGAATG
GTTGTTTGCCCCATTCATCGATGCACTACAGCAGGCGAGTCTTGGCGTGCAATTGTTTATGCGGATCCTAATCACCCATG
TACTTTGGTGTTTTGGGGTGCATGGCGATAATGCCTATCTGCTGCTGATTGGTGTCGATAATGGCTTAATGGAATTGGTG
CCGCACCTGACTGCGAGCCAGTTTATGGACTTGTTTATTATCTATGGCGGTAGTGGCGCCACCCTATCCTTAATCATTGC
CATTTTTATCGGTGCCAAAGATAGCGCCACTCGGCATATTGCTAAAATTGCCACGCCCTTTGCGATTTTTAACATCAACG
AGATTTTGATCTATGGCCTCCCCATTATCTTTAATCCACGTTTATTAGTGCCGTTTATTCTGTCGCCGTTGATTAATTTC
ATCTTAGCTTACAGTGCTATCCATGCTGGGATCTTGAGTTTTGAGGGACAAAGCTTTCCTTGGATCACGCCGCCACTGCT
AAACGCTTACATTGCCAGCGGCCATTTGAGCGCGGTGTTTTTTCAAGTGTTTTTAATCGGCCTTGGGGTGTTGATTTATC
TTCCCTTTGTGCGGCGTTTCTCCTTGATGTCTGAGCACTATGAGTTTGATAGCGAGTTAATCAAACGCGTGCAGTTTCAG
GCGGATATTGACCGTATGACCGAGCAGCATTACTCACAGCAGCAGTCTGAATCACTAAAAGCTGAATTAAACCTCGAGAA
GACCATTAAAGAAGTCTTGGCTGGGGAGTTACAGCTGCATTATCAGCCAAAAATTGCCCTCAGCAGTGACCATGTAGTGG
GGTTTGAGGCGCTTATACGATTGAAGGATGAACATGGTCACTTGAAGGGACCTTACTTTATTGATGCCTTTCAACGAGCG
GGGTATTCCCACATCATCGACCGTTTTGTAATAAATACGGTGGCAGAGGATCTGGCCCGCTGGGAATTAGAAGGCTTTTT
GCCTAAGGTGAGCATCAATATCGACCCAAACAATATTACCGATCCCCAGTTGCTCGCGACGTTGCACGAAAGATTAGGCA
GCGTTGCCGACCGAGTCGAGATTGAGATGTTAGAATCGGCCTTTATGTTAGATTTGAATCGCATCGATAGCAGCATGAGG
CAGCTTAAACAATATGGCTTTCGCTTCTTATTAGATGATTTCGGTACTGGGTTTTCGAGTTTAAGTTTACTGAGTCGGAT
CAATGTCGATGGGATTAAGCTCGACCGCAGTATTCTGGCGAATACCAATGAGCCTAAAGGGCGGACTTTGTACCTACAAA
TCTGTAAGCTTTGTAATAGTTTAGGCTTTAGTTTGATTGCCGAAGGGGTTGAAACGCCCGCCGAGGCCGAGTTTGTCAAA
GAGGCGGGTGTGGGTTATGTGCAGGGCTGGTTATACGCCAAAGCGATGCCAGGCCCCGAGGCCAAAGCCTTTTGGTTGGA
GAGAAATAGTGACTAA

Upstream 100 bases:

>100_bases
GCTTGTTCTTGCTTGGAAATTCAGTATTTAGCGCATTGGGTTATGAGGAATACTGAGTATCGACTATGGTTAGTGCATAT
AAACCTATATAAATAGCGCT

Downstream 100 bases:

>100_bases
TACTTTAGTCAGCACCCTGCTGACGACATACGCCAATGTGAGCTTGTCGGCTTGGGATAATTTGCGAGTCTTGCTATCCG
AGTGTGCGTTGCAGCAATGT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MKFELRQFLDRSFLISIRESFIALLPFILINSFLSLIITLLDLSIPAWQSTAFHQSISFFSVQLSKIFPLLALISLSFHF
AKYLQLSAIVVCSLSLSLLLAINAQDTGNVFNLDYVRAILADPRIAVLPIISAYLLRFLTAWNGLTFIRAKALSRYLKLH
LNLFFPIVIGFIGLFAIVAEASIFLEWLFAPFIDALQQASLGVQLFMRILITHVLWCFGVHGDNAYLLLIGVDNGLMELV
PHLTASQFMDLFIIYGGSGATLSLIIAIFIGAKDSATRHIAKIATPFAIFNINEILIYGLPIIFNPRLLVPFILSPLINF
ILAYSAIHAGILSFEGQSFPWITPPLLNAYIASGHLSAVFFQVFLIGLGVLIYLPFVRRFSLMSEHYEFDSELIKRVQFQ
ADIDRMTEQHYSQQQSESLKAELNLEKTIKEVLAGELQLHYQPKIALSSDHVVGFEALIRLKDEHGHLKGPYFIDAFQRA
GYSHIIDRFVINTVAEDLARWELEGFLPKVSINIDPNNITDPQLLATLHERLGSVADRVEIEMLESAFMLDLNRIDSSMR
QLKQYGFRFLLDDFGTGFSSLSLLSRINVDGIKLDRSILANTNEPKGRTLYLQICKLCNSLGFSLIAEGVETPAEAEFVK
EAGVGYVQGWLYAKAMPGPEAKAFWLERNSD

Sequences:

>Translated_671_residues
MKFELRQFLDRSFLISIRESFIALLPFILINSFLSLIITLLDLSIPAWQSTAFHQSISFFSVQLSKIFPLLALISLSFHF
AKYLQLSAIVVCSLSLSLLLAINAQDTGNVFNLDYVRAILADPRIAVLPIISAYLLRFLTAWNGLTFIRAKALSRYLKLH
LNLFFPIVIGFIGLFAIVAEASIFLEWLFAPFIDALQQASLGVQLFMRILITHVLWCFGVHGDNAYLLLIGVDNGLMELV
PHLTASQFMDLFIIYGGSGATLSLIIAIFIGAKDSATRHIAKIATPFAIFNINEILIYGLPIIFNPRLLVPFILSPLINF
ILAYSAIHAGILSFEGQSFPWITPPLLNAYIASGHLSAVFFQVFLIGLGVLIYLPFVRRFSLMSEHYEFDSELIKRVQFQ
ADIDRMTEQHYSQQQSESLKAELNLEKTIKEVLAGELQLHYQPKIALSSDHVVGFEALIRLKDEHGHLKGPYFIDAFQRA
GYSHIIDRFVINTVAEDLARWELEGFLPKVSINIDPNNITDPQLLATLHERLGSVADRVEIEMLESAFMLDLNRIDSSMR
QLKQYGFRFLLDDFGTGFSSLSLLSRINVDGIKLDRSILANTNEPKGRTLYLQICKLCNSLGFSLIAEGVETPAEAEFVK
EAGVGYVQGWLYAKAMPGPEAKAFWLERNSD
>Mature_671_residues
MKFELRQFLDRSFLISIRESFIALLPFILINSFLSLIITLLDLSIPAWQSTAFHQSISFFSVQLSKIFPLLALISLSFHF
AKYLQLSAIVVCSLSLSLLLAINAQDTGNVFNLDYVRAILADPRIAVLPIISAYLLRFLTAWNGLTFIRAKALSRYLKLH
LNLFFPIVIGFIGLFAIVAEASIFLEWLFAPFIDALQQASLGVQLFMRILITHVLWCFGVHGDNAYLLLIGVDNGLMELV
PHLTASQFMDLFIIYGGSGATLSLIIAIFIGAKDSATRHIAKIATPFAIFNINEILIYGLPIIFNPRLLVPFILSPLINF
ILAYSAIHAGILSFEGQSFPWITPPLLNAYIASGHLSAVFFQVFLIGLGVLIYLPFVRRFSLMSEHYEFDSELIKRVQFQ
ADIDRMTEQHYSQQQSESLKAELNLEKTIKEVLAGELQLHYQPKIALSSDHVVGFEALIRLKDEHGHLKGPYFIDAFQRA
GYSHIIDRFVINTVAEDLARWELEGFLPKVSINIDPNNITDPQLLATLHERLGSVADRVEIEMLESAFMLDLNRIDSSMR
QLKQYGFRFLLDDFGTGFSSLSLLSRINVDGIKLDRSILANTNEPKGRTLYLQICKLCNSLGFSLIAEGVETPAEAEFVK
EAGVGYVQGWLYAKAMPGPEAKAFWLERNSD

Specific function: Overexpression reduces biofilm formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=33.6134453781513, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081743, Length=226, Percent_Identity=33.1858407079646, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1787541, Length=321, Percent_Identity=30.2180685358255, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788032, Length=206, Percent_Identity=36.8932038834951, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081921, Length=265, Percent_Identity=30.188679245283, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI226510982, Length=259, Percent_Identity=28.1853281853282, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081845, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788849, Length=221, Percent_Identity=26.6968325791855, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788502, Length=225, Percent_Identity=29.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787055, Length=234, Percent_Identity=28.6324786324786, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87081980, Length=229, Percent_Identity=29.6943231441048, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=31.7880794701987, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786507, Length=109, Percent_Identity=36.697247706422, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082280, Length=103, Percent_Identity=36.8932038834951, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 75432; Mature: 75432

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51105 PTS_EIIC_TYPE_3 ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFELRQFLDRSFLISIRESFIALLPFILINSFLSLIITLLDLSIPAWQSTAFHQSISFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SVQLSKIFPLLALISLSFHFAKYLQLSAIVVCSLSLSLLLAINAQDTGNVFNLDYVRAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEECHHHHHHHH
ADPRIAVLPIISAYLLRFLTAWNGLTFIRAKALSRYLKLHLNLFFPIVIGFIGLFAIVAE
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIFLEWLFAPFIDALQQASLGVQLFMRILITHVLWCFGVHGDNAYLLLIGVDNGLMELV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHH
PHLTASQFMDLFIIYGGSGATLSLIIAIFIGAKDSATRHIAKIATPFAIFNINEILIYGL
HHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEHHHHHHCCC
PIIFNPRLLVPFILSPLINFILAYSAIHAGILSFEGQSFPWITPPLLNAYIASGHLSAVF
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCHHHHHH
FQVFLIGLGVLIYLPFVRRFSLMSEHYEFDSELIKRVQFQADIDRMTEQHYSQQQSESLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELNLEKTIKEVLAGELQLHYQPKIALSSDHVVGFEALIRLKDEHGHLKGPYFIDAFQRA
HHCCHHHHHHHHHHCHHEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GYSHIIDRFVINTVAEDLARWELEGFLPKVSINIDPNNITDPQLLATLHERLGSVADRVE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
IEMLESAFMLDLNRIDSSMRQLKQYGFRFLLDDFGTGFSSLSLLSRINVDGIKLDRSILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECHHHHC
NTNEPKGRTLYLQICKLCNSLGFSLIAEGVETPAEAEFVKEAGVGYVQGWLYAKAMPGPE
CCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHEECCCCCC
AKAFWLERNSD
CCEEEEECCCC
>Mature Secondary Structure
MKFELRQFLDRSFLISIRESFIALLPFILINSFLSLIITLLDLSIPAWQSTAFHQSISFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SVQLSKIFPLLALISLSFHFAKYLQLSAIVVCSLSLSLLLAINAQDTGNVFNLDYVRAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEECHHHHHHHH
ADPRIAVLPIISAYLLRFLTAWNGLTFIRAKALSRYLKLHLNLFFPIVIGFIGLFAIVAE
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIFLEWLFAPFIDALQQASLGVQLFMRILITHVLWCFGVHGDNAYLLLIGVDNGLMELV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHH
PHLTASQFMDLFIIYGGSGATLSLIIAIFIGAKDSATRHIAKIATPFAIFNINEILIYGL
HHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEHHHHHHCCC
PIIFNPRLLVPFILSPLINFILAYSAIHAGILSFEGQSFPWITPPLLNAYIASGHLSAVF
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCHHHHHH
FQVFLIGLGVLIYLPFVRRFSLMSEHYEFDSELIKRVQFQADIDRMTEQHYSQQQSESLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELNLEKTIKEVLAGELQLHYQPKIALSSDHVVGFEALIRLKDEHGHLKGPYFIDAFQRA
HHCCHHHHHHHHHHCHHEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GYSHIIDRFVINTVAEDLARWELEGFLPKVSINIDPNNITDPQLLATLHERLGSVADRVE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
IEMLESAFMLDLNRIDSSMRQLKQYGFRFLLDDFGTGFSSLSLLSRINVDGIKLDRSILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECHHHHC
NTNEPKGRTLYLQICKLCNSLGFSLIAEGVETPAEAEFVKEAGVGYVQGWLYAKAMPGPE
CCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHEECCCCCC
AKAFWLERNSD
CCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]