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The map label for this gene is mlhB [H]

Identifier: 113968954

GI number: 113968954

Start: 704211

End: 705122

Strand: Direct

Name: mlhB [H]

Synonym: Shewmr4_0610

Alternate gene names: 113968954

Gene position: 704211-705122 (Clockwise)

Preceding gene: 113968953

Following gene: 113968955

Centisome position: 14.96

GC content: 50.22

Gene sequence:

>912_bases
ATGCCAAGCTGGCAAGCATCTGTATTAAATACTATTTTATCCTATGTGGCACGGCCATCCATCAGCCGTGGTAAAGCCAA
GCTCCCCCTAAATCAAGTGAGACAACGCTTATTAGAGCTGGATAAGCGCTGGTTGCCGTGGCCCGAAAAACTCGTTACGG
CCTCGATTACCTTACAACATTCTACCCTGTTGCATTATGTGCTGCTGAATGACACGCCGCGTTTGGGCAACCTGTTTTAC
ATTCGTGGCGGCGGATTTTGTTTTAAAACTCCCCATGCCCACGCAAGACTGGTGGCCGATATCAGTGAACGTTGTCGCCT
CGATACGTTTATCCCAGATTATCGTTTAGCGCCGGAGCATCCGTATCCCGCGCCCTGTGACGATGTGCTCGAGGCTTATC
TGCACTTAATTGAGTTGAAAGGCAGCGATAATCTGGTGTTGATGGGCGATTCTGCCGGCGGCAATTTAGCCTTGAGTCTG
TTGCTCGAACTGAAAAAGCGCCATCTGCCTATGCCTAAAGCCTGTGTGTTGTTGTCACCCGCACTCGATTTAGCCATTAC
CGGCGATACCGAGCTGATTTTAGGGGCGGACGATCCGTTCTTTACCATTGAGTCGCTTTTGCGGCTGCGCGGCGCTTATC
TTGCCGGGGCGAATCCTATGTCTGAACGGGTTTCACCTTTACAGGGGAACTTGGCTGACTTGCCGCCACTCTTAGTGATT
GCCGGTACGCGCGAGTTGCTTTTACAAGATTCAGAACGACTGGTTATGCAAATTAAGGCCTGTGGTGGTGCGGTAGAATC
GCGTTTTTATCACAACATGCCCCATGTTTTTCCCCTGTTCCATCTGTTGCCAGAAGCGATTGAGGCGAGGGAACAAATTG
CAGATTTTGTGCTTTCACAGCTGATTCGTTAA

Upstream 100 bases:

>100_bases
CTGCGCCTAAAAGCACAGAATTATCGGAAGTTGGATCTGCTGTGATCTGCACGCCGTTCCCATCGGTGTCCTATTGCGGC
ACTGATGTGGAGGACGGGAA

Downstream 100 bases:

>100_bases
AATTGTGTAGTTATTCATATTCAGTGAATAGCTAGCAAAAATAGGGGTAAATAACTTTTTTTCTGACTAAATATGCTAAA
GGCCTCTGGCGTAAACGCTT

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPSWQASVLNTILSYVARPSISRGKAKLPLNQVRQRLLELDKRWLPWPEKLVTASITLQHSTLLHYVLLNDTPRLGNLFY
IRGGGFCFKTPHAHARLVADISERCRLDTFIPDYRLAPEHPYPAPCDDVLEAYLHLIELKGSDNLVLMGDSAGGNLALSL
LLELKKRHLPMPKACVLLSPALDLAITGDTELILGADDPFFTIESLLRLRGAYLAGANPMSERVSPLQGNLADLPPLLVI
AGTRELLLQDSERLVMQIKACGGAVESRFYHNMPHVFPLFHLLPEAIEAREQIADFVLSQLIR

Sequences:

>Translated_303_residues
MPSWQASVLNTILSYVARPSISRGKAKLPLNQVRQRLLELDKRWLPWPEKLVTASITLQHSTLLHYVLLNDTPRLGNLFY
IRGGGFCFKTPHAHARLVADISERCRLDTFIPDYRLAPEHPYPAPCDDVLEAYLHLIELKGSDNLVLMGDSAGGNLALSL
LLELKKRHLPMPKACVLLSPALDLAITGDTELILGADDPFFTIESLLRLRGAYLAGANPMSERVSPLQGNLADLPPLLVI
AGTRELLLQDSERLVMQIKACGGAVESRFYHNMPHVFPLFHLLPEAIEAREQIADFVLSQLIR
>Mature_302_residues
PSWQASVLNTILSYVARPSISRGKAKLPLNQVRQRLLELDKRWLPWPEKLVTASITLQHSTLLHYVLLNDTPRLGNLFYI
RGGGFCFKTPHAHARLVADISERCRLDTFIPDYRLAPEHPYPAPCDDVLEAYLHLIELKGSDNLVLMGDSAGGNLALSLL
LELKKRHLPMPKACVLLSPALDLAITGDTELILGADDPFFTIESLLRLRGAYLAGANPMSERVSPLQGNLADLPPLLVIA
GTRELLLQDSERLVMQIKACGGAVESRFYHNMPHVFPLFHLLPEAIEAREQIADFVLSQLIR

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 33774; Mature: 33643

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSWQASVLNTILSYVARPSISRGKAKLPLNQVRQRLLELDKRWLPWPEKLVTASITLQH
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEEEEEEH
STLLHYVLLNDTPRLGNLFYIRGGGFCFKTPHAHARLVADISERCRLDTFIPDYRLAPEH
HHHEEEEEECCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYPAPCDDVLEAYLHLIELKGSDNLVLMGDSAGGNLALSLLLELKKRHLPMPKACVLLSP
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHEEECC
ALDLAITGDTELILGADDPFFTIESLLRLRGAYLAGANPMSERVSPLQGNLADLPPLLVI
CCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEE
AGTRELLLQDSERLVMQIKACGGAVESRFYHNMPHVFPLFHLLPEAIEAREQIADFVLSQ
ECCHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC
>Mature Secondary Structure 
PSWQASVLNTILSYVARPSISRGKAKLPLNQVRQRLLELDKRWLPWPEKLVTASITLQH
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEEEEEEH
STLLHYVLLNDTPRLGNLFYIRGGGFCFKTPHAHARLVADISERCRLDTFIPDYRLAPEH
HHHEEEEEECCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYPAPCDDVLEAYLHLIELKGSDNLVLMGDSAGGNLALSLLLELKKRHLPMPKACVLLSP
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHEEECC
ALDLAITGDTELILGADDPFFTIESLLRLRGAYLAGANPMSERVSPLQGNLADLPPLLVI
CCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEE
AGTRELLLQDSERLVMQIKACGGAVESRFYHNMPHVFPLFHLLPEAIEAREQIADFVLSQ
ECCHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA