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The map label for this gene is sloC [H]

Identifier: 113968911

GI number: 113968911

Start: 649934

End: 650842

Strand: Direct

Name: sloC [H]

Synonym: Shewmr4_0567

Alternate gene names: 113968911

Gene position: 649934-650842 (Clockwise)

Preceding gene: 113968910

Following gene: 113968912

Centisome position: 13.81

GC content: 53.25

Gene sequence:

>909_bases
GTGCGCATCAATTCTAATTTTGTTAAAGCGGCCGCAGCGGCCCTGTCTTTCGCTTGTTCAGGCTTTGCCCACGCAGAGCT
GAATGTGTTTGCCTGTGAACCCGAATATGCCGCATTGGCAAAAGAGTTGGCTCCAAACGCCAGCATTTATTCGGCAACCA
CGGCCTTACAGGATCCGCATCAAGTGCAGGCGCGTCCGAGTTTGATCGCCAAAATGCGCCAAGCGGATCTGGTGGTCTGT
GCGGGCGCCGATTTAGAAATCGGTTGGCTGCCAATGCTGCAAATGAAGTCGGCTAACGCTAAGGTTCGCTCTACCGATCA
GGGGCTGTTTTTCGCCGCCGATCAAATCGATACCTTAGATAAGTTAGCGAGTGTGGACCGTAGCATGGGGGATGTGCATG
CTCAGGGAAATCCGCATATCCACTTCGATCCGACGCGTTTGCTAAGCGTCGCGAATGCGCTCAGCGCTAAGATGAGCCAA
CTCGACCCGAGCGAGGCGGCGAATTACCAAAAGGCATTAGCGGACTTTAGTACTCGTTGGCAGGCGGCGGTCCCCCGCTG
GGAAGAGCAGGCCAAAGCGTTAAAAGGCAAAAAGGTCATCGCCTATCACACCAGTTTTAGATATCTGTTCAACTGGTTGG
GGATTGAACAAGCTGCTGATCTTGAGCCTAAACCCGGTCTGGCACCGACTAGCGGTCATTTAGCGAGTTTGCTGAGCCGT
GCTGAGCAGGGCGATATTCTGGCGGTAGTTGTGGCGTCCTATCAGGATGAGCGTGGTGCTAAGTGGTTGGGTGAAAAGGC
TAATCTACCAGTGCTTATGTTGCCAATGTCGGTAGGTGGCAACGATGCGAGTCAAGATCTCTTCAGCCTCTACGACAGCG
CTATTGCCCTCTTAAACGGGGTGAAATAA

Upstream 100 bases:

>100_bases
GTACGTTTCCAGTACACCAATCAGAAGGGAACTAACTTCGATGGAATCGAAGACGACAATGTTTTCACTGTTCAATACAT
TATGTCTCTGGGGGCTCACG

Downstream 100 bases:

>100_bases
GCCTATGTTGGATCTGGAACTGATGTCGATCCTGCTGCCAGCATTGACGGCGGGGATCTTAGTGCTCTCAACGCATATTG
TACTTGGCAAACAAGTGCTT

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRINSNFVKAAAAALSFACSGFAHAELNVFACEPEYAALAKELAPNASIYSATTALQDPHQVQARPSLIAKMRQADLVVC
AGADLEIGWLPMLQMKSANAKVRSTDQGLFFAADQIDTLDKLASVDRSMGDVHAQGNPHIHFDPTRLLSVANALSAKMSQ
LDPSEAANYQKALADFSTRWQAAVPRWEEQAKALKGKKVIAYHTSFRYLFNWLGIEQAADLEPKPGLAPTSGHLASLLSR
AEQGDILAVVVASYQDERGAKWLGEKANLPVLMLPMSVGGNDASQDLFSLYDSAIALLNGVK

Sequences:

>Translated_302_residues
MRINSNFVKAAAAALSFACSGFAHAELNVFACEPEYAALAKELAPNASIYSATTALQDPHQVQARPSLIAKMRQADLVVC
AGADLEIGWLPMLQMKSANAKVRSTDQGLFFAADQIDTLDKLASVDRSMGDVHAQGNPHIHFDPTRLLSVANALSAKMSQ
LDPSEAANYQKALADFSTRWQAAVPRWEEQAKALKGKKVIAYHTSFRYLFNWLGIEQAADLEPKPGLAPTSGHLASLLSR
AEQGDILAVVVASYQDERGAKWLGEKANLPVLMLPMSVGGNDASQDLFSLYDSAIALLNGVK
>Mature_302_residues
MRINSNFVKAAAAALSFACSGFAHAELNVFACEPEYAALAKELAPNASIYSATTALQDPHQVQARPSLIAKMRQADLVVC
AGADLEIGWLPMLQMKSANAKVRSTDQGLFFAADQIDTLDKLASVDRSMGDVHAQGNPHIHFDPTRLLSVANALSAKMSQ
LDPSEAANYQKALADFSTRWQAAVPRWEEQAKALKGKKVIAYHTSFRYLFNWLGIEQAADLEPKPGLAPTSGHLASLLSR
AEQGDILAVVVASYQDERGAKWLGEKANLPVLMLPMSVGGNDASQDLFSLYDSAIALLNGVK

Specific function: Part of an ATP-driven transport system for a metal; probably for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection. It may contribute to the formation and accu

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32541; Mature: 32541

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINSNFVKAAAAALSFACSGFAHAELNVFACEPEYAALAKELAPNASIYSATTALQDPH
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEHHHHHCCCH
QVQARPSLIAKMRQADLVVCAGADLEIGWLPMLQMKSANAKVRSTDQGLFFAADQIDTLD
HHHCCHHHHHHHHHCCEEEEECCCCEECCCCCEEECCCCCEEEECCCCEEEEHHHHHHHH
KLASVDRSMGDVHAQGNPHIHFDPTRLLSVANALSAKMSQLDPSEAANYQKALADFSTRW
HHHHHHHHHCCEECCCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QAAVPRWEEQAKALKGKKVIAYHTSFRYLFNWLGIEQAADLEPKPGLAPTSGHLASLLSR
HHHCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
AEQGDILAVVVASYQDERGAKWLGEKANLPVLMLPMSVGGNDASQDLFSLYDSAIALLNG
CCCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHC
VK
CC
>Mature Secondary Structure
MRINSNFVKAAAAALSFACSGFAHAELNVFACEPEYAALAKELAPNASIYSATTALQDPH
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEHHHHHCCCH
QVQARPSLIAKMRQADLVVCAGADLEIGWLPMLQMKSANAKVRSTDQGLFFAADQIDTLD
HHHCCHHHHHHHHHCCEEEEECCCCEECCCCCEEECCCCCEEEECCCCEEEEHHHHHHHH
KLASVDRSMGDVHAQGNPHIHFDPTRLLSVANALSAKMSQLDPSEAANYQKALADFSTRW
HHHHHHHHHCCEECCCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QAAVPRWEEQAKALKGKKVIAYHTSFRYLFNWLGIEQAADLEPKPGLAPTSGHLASLLSR
HHHCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
AEQGDILAVVVASYQDERGAKWLGEKANLPVLMLPMSVGGNDASQDLFSLYDSAIALLNG
CCCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10899841; 12397186 [H]