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The map label for this gene is yciR [C]

Identifier: 113968889

GI number: 113968889

Start: 629743

End: 631461

Strand: Direct

Name: yciR [C]

Synonym: Shewmr4_0545

Alternate gene names: 113968889

Gene position: 629743-631461 (Clockwise)

Preceding gene: 113968888

Following gene: 113968890

Centisome position: 13.38

GC content: 44.33

Gene sequence:

>1719_bases
ATGGACTTACTACTGATCGATGATGATGACGTCGATAGAACTGCCATTATTAGGGCATTGCGACAGTCGAAATTAGCCTT
TAACGTGATTGAGGCAAACTGTGCTTTCGATGGTTTAAACCTAGCACTAGAGCGCCATTTTGACGGCATATTACTCGATT
ATTTGTTGCCCGATGCTAATGGATTGGAAGTGTTGATCAAACTCAACTCTATGACTCAGGAACAAACAGTCGTGTTAATG
TTGAGTCGCTATGAAGATGAAAAACTGGCGCAGCGTTGCATCGAGTTAGGTGCGCAGGATTTTTTACTGAAAGATGAAGT
CAATTCAAGAATCTTAAGCCGTTCAATTCGTTACGCCAAACAACGTGCCTCTATGGCGCTAGCCTTACGAAATAGCCACC
AAAAACTAAAAGAATTGGCCGAGCACGATTCGCTCACTAAATTAATGAATCGCTATGGGTTTGAGTTGTGTCTGAATCGA
GCGATTGCGAGGGCTAAACGCAGTAATGATTTTTTAGCGGTAATATTACTCGATCTCGATGATTTTAAAGCGATTAATGA
CACATTGGGGCATCAAACGGGTGACATCCTATTAGTAAAGGTGGCGTCGAGGTTAAGTTCGGTATTGCGAGATGGGGATG
TTATTGCACGCTTAGGCGGTGATGAGTTTGTGGTGCTGGTGACCGACAATGACTACAAATACTTCCCCATGATAGTCGCC
AATCGCCTGCTGAAGGCTTTCGAAGAAGTGTTTGGTCTTGGGGATAACGATGTCATGATCGGTGCCAGTATTGGAGTCGC
CTTTTATAACGAGGCGGCATCCAATAGCTCCGAATTGATGAAATGTGCCGATATCGCCATGTATCGCGCGAAAAAAATGG
GCCGTAACCAGATCCAATTTTATTCCGAAGCGTTAGACCGTGAAGTGCGTTATCGCAATCATATCGAATCTAGTCTGAGA
ATGGCTCAGAAGCAGAATGAACTTAAAGTTTACTATCAGGCGCAAGTCGATTCGAAAACACACCAAATTATCGGTATGGA
AGCGTTAATCCGTTGGTTGCATCCACAAGATGGATTGATTTCACCGGACCAGTTTCTGCCCATTGCTGAAGAAATCGGAC
TGATGGAGGAAATTGGAGATTGGATCCTGCTTGAGGCGTGCCGACAGGCGCAGCAATGGCTGAAGCAGTTAGCTCCTACG
GGACATAGTTTTACCATGGCGGTAAACTTGTCAGCATCGCAAATTGGTCATATTGATCTCTATGAGAAAATTGTGAAAAT
GCTAGCCGAAACAGGGCTTTCACCAAAGGCGCTGGAATTAGAGATTACCGAAAACTGTTTGATTGAAGAACCCCATGAGC
ATGCCAAGGTGCTGGATAAAATTGCGCAACTCGGGGTGCGATTTGCCCTCGATGACTTTGGCACAGGTTTTTCGTCATTA
GAGCATATAAAGCTGTTTCCTATCAGTGTGTTAAAAATCGACAAGAGCTTTATCGCCTCCTACGATAAGGATGAAAAGGA
CGCTCGGTTACTCACGGCACTACTCAATTTTGCCTATGGTTTTAATGTCACATCTGTTGCTGAAGGGATTGAAACCGTTG
AACAAGCCGAGTTTTGCACCGAAAGACACTGTGACGTGTTGCAGGGGTACCTTTTCTCACGCCCCATAGAAGCAAGTGAA
TTTGAAGCAAAGTTCATCATTCCTTTACTTCCTAAATAG

Upstream 100 bases:

>100_bases
CATGGTGAAAACGGATATTAAAGACGGTTTTAATAACATTTTTAATATGTTGGAAGGTTACTGGCGCATAGTGGAGCTTC
CAAGCGTATAGGGGGTGTAT

Downstream 100 bases:

>100_bases
TGCTCCTAAATTGTGAAGATTATCTTACGTTTGGCTATGGCTTAGGTTTTCGTCTGGTGAGGAATATTTTCTTGCTTTAC
ACTCAGCAATAGACAAATAT

Product: response regulator receiver modulated diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MDLLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGLEVLIKLNSMTQEQTVVLM
LSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAKQRASMALALRNSHQKLKELAEHDSLTKLMNRYGFELCLNR
AIARAKRSNDFLAVILLDLDDFKAINDTLGHQTGDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVA
NRLLKAFEEVFGLGDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQFYSEALDREVRYRNHIESSLR
MAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLISPDQFLPIAEEIGLMEEIGDWILLEACRQAQQWLKQLAPT
GHSFTMAVNLSASQIGHIDLYEKIVKMLAETGLSPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSL
EHIKLFPISVLKIDKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCTERHCDVLQGYLFSRPIEASE
FEAKFIIPLLPK

Sequences:

>Translated_572_residues
MDLLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGLEVLIKLNSMTQEQTVVLM
LSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAKQRASMALALRNSHQKLKELAEHDSLTKLMNRYGFELCLNR
AIARAKRSNDFLAVILLDLDDFKAINDTLGHQTGDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVA
NRLLKAFEEVFGLGDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQFYSEALDREVRYRNHIESSLR
MAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLISPDQFLPIAEEIGLMEEIGDWILLEACRQAQQWLKQLAPT
GHSFTMAVNLSASQIGHIDLYEKIVKMLAETGLSPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSL
EHIKLFPISVLKIDKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCTERHCDVLQGYLFSRPIEASE
FEAKFIIPLLPK
>Mature_572_residues
MDLLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGLEVLIKLNSMTQEQTVVLM
LSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAKQRASMALALRNSHQKLKELAEHDSLTKLMNRYGFELCLNR
AIARAKRSNDFLAVILLDLDDFKAINDTLGHQTGDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVA
NRLLKAFEEVFGLGDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQFYSEALDREVRYRNHIESSLR
MAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLISPDQFLPIAEEIGLMEEIGDWILLEACRQAQQWLKQLAPT
GHSFTMAVNLSASQIGHIDLYEKIVKMLAETGLSPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSL
EHIKLFPISVLKIDKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCTERHCDVLQGYLFSRPIEASE
FEAKFIIPLLPK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=34.1801385681293, Blast_Score=266, Evalue=4e-72,
Organism=Escherichia coli, GI87081921, Length=464, Percent_Identity=32.5431034482759, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI226510982, Length=442, Percent_Identity=27.8280542986425, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI1786507, Length=254, Percent_Identity=31.496062992126, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1787055, Length=445, Percent_Identity=26.2921348314607, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=32.2709163346614, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=31.25, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=29.2181069958848, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=31.3492063492063, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788381, Length=402, Percent_Identity=27.1144278606965, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=29.2181069958848, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693134, Length=207, Percent_Identity=32.3671497584541, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=34.2541436464088, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=34.1040462427746, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788849, Length=441, Percent_Identity=25.1700680272109, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=32.0388349514563, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082096, Length=247, Percent_Identity=25.9109311740891, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=37.125748502994, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=35.3293413173653, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787802, Length=210, Percent_Identity=30.4761904761905, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788085, Length=206, Percent_Identity=33.0097087378641, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=35.1190476190476, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=30.6748466257669, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=159, Percent_Identity=34.5911949685535, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=98, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 64639; Mature: 64639

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDAN
CEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCEEHHHHCCCCC
GLEVLIKLNSMTQEQTVVLMLSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAK
CCEEEEEECCCCCHHHHEEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRASMALALRNSHQKLKELAEHDSLTKLMNRYGFELCLNRAIARAKRSNDFLAVILLDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
DFKAINDTLGHQTGDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCEEHHHHHH
NRLLKAFEEVFGLGDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQF
HHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
YSEALDREVRYRNHIESSLRMAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCC
SPDQFLPIAEEIGLMEEIGDWILLEACRQAQQWLKQLAPTGHSFTMAVNLSASQIGHIDL
CCHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCHHH
YEKIVKMLAETGLSPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EHIKLFPISVLKIDKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCT
CCEEEEEHHHEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ERHCDVLQGYLFSRPIEASEFEAKFIIPLLPK
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MDLLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDAN
CEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCEEHHHHCCCCC
GLEVLIKLNSMTQEQTVVLMLSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAK
CCEEEEEECCCCCHHHHEEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRASMALALRNSHQKLKELAEHDSLTKLMNRYGFELCLNRAIARAKRSNDFLAVILLDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
DFKAINDTLGHQTGDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCEEHHHHHH
NRLLKAFEEVFGLGDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQF
HHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
YSEALDREVRYRNHIESSLRMAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCC
SPDQFLPIAEEIGLMEEIGDWILLEACRQAQQWLKQLAPTGHSFTMAVNLSASQIGHIDL
CCHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCHHH
YEKIVKMLAETGLSPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EHIKLFPISVLKIDKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCT
CCEEEEEHHHEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ERHCDVLQGYLFSRPIEASEFEAKFIIPLLPK
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]