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The map label for this gene is emrK [H]

Identifier: 113968867

GI number: 113968867

Start: 602377

End: 603432

Strand: Direct

Name: emrK [H]

Synonym: Shewmr4_0523

Alternate gene names: 113968867

Gene position: 602377-603432 (Clockwise)

Preceding gene: 113968864

Following gene: 113968868

Centisome position: 12.8

GC content: 53.6

Gene sequence:

>1056_bases
ATGTCCAAAAGTAAGCTCATCATCGCCGTTCCACTGATACTCGCCGCTGTCGCGGGTGGCGGCTATTACTGGTGGACGCA
AGTACGTTTTATCGAAACCACTGACAACGCCTATGTTGAGGCCGATATCTCCCATGTGAGCGTGAAAGTCCCAGGTTATG
TGGTGATATCCGATGTGACCGATAACCAGCATGTGCGCAAGGGCGAGTTATTGGCGCAACTTGAAGATAACCAGTTTAGC
GCCAAAGTCAGCCAAGCCGAGGCGTCACTCGGCAGTGCTAAGGCCGATCTGCAAACCTTAGCCGCTAAGGTGGAATTACA
ACATGCGTTGATCAGTCAAGCGAGTGCGGGCGTGGTCGCGGCGCAGGCCGACAAACTGCGCGCCGAGCAACAGTTAACTC
GTGCTAAAAAGTTAAAAGTCAGCAACTACAGCTCACAGGACGATGTCGACCAATTGCAAGCGGGTTTTGATTCTGCCGCC
GCTGGGCTGGATGAAGCCAAGGCACTGTTAGTGGCTAAAGAGCGTGAGCTTGCCGTGTTCAATGCCCAGCTTAATCAAGC
TGGCTCTGTGGTTGAACAGTCGAATGCGGCATTGGAGCTGGCTAAAATTCAGCTTAATGATACCCGCGTAACCGCGCCTT
TCTCTGGGGTGATTGGTAAACGCGGCGCCATGGTGGGGCAATATGTGCAGCCCGGCCAGGCACTCTACAGTTTGGTTCCG
GATGGGGCTGTGTGGATCACGGCGAACTTTAAAGAAACCCAAATCCAACATATGCAACCTGGGCAGTCGGTGCAGGTCAG
TCTCGATGCGTTTCCCGACAAAACCTTTACAGGTGTTATCGATAGTCTGTCGCCGGCGTCCGGAGCCAAATTTAGTCTGC
TGCCCGCCGAAAATGCCACGGGTAACTTCACTAAAATCGTGCAACGTATTCCGGTGCGGATCCGTTTAGATCTCTCAGAA
GAAGAGGCACGTGTCGTCCCCGGTTTAAGTGCCGTGGTGAAGGTCGATACTGCGTCGCATCCGACGACAGCTATCGCTGC
TAACGTCGGTCGCTAA

Upstream 100 bases:

>100_bases
CATGATTGTTACACCTGTGAAACAGTGGGTTGATTTTTAACTATCTAATAAACGTGATGAGACAGTAGTACACTAGCACT
CACTAATCAAGGAGTCATTC

Downstream 100 bases:

>100_bases
GTCGGTCGTTAACATGAGCACAATTGCTGCGGCACCTGAAGCTATCGCCGCGGGGGCTACACCGAGCGAATATGAGCGTG
GTAGTCGCCGTTCGTGGATT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSKSKLIIAVPLILAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVISDVTDNQHVRKGELLAQLEDNQFS
AKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLTRAKKLKVSNYSSQDDVDQLQAGFDSAA
AGLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSE
EEARVVPGLSAVVKVDTASHPTTAIAANVGR

Sequences:

>Translated_351_residues
MSKSKLIIAVPLILAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVISDVTDNQHVRKGELLAQLEDNQFS
AKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLTRAKKLKVSNYSSQDDVDQLQAGFDSAA
AGLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSE
EEARVVPGLSAVVKVDTASHPTTAIAANVGR
>Mature_350_residues
SKSKLIIAVPLILAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVISDVTDNQHVRKGELLAQLEDNQFSA
KVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLTRAKKLKVSNYSSQDDVDQLQAGFDSAAA
GLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVPD
GAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSEE
EARVVPGLSAVVKVDTASHPTTAIAANVGR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=335, Percent_Identity=32.5373134328358, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789041, Length=342, Percent_Identity=31.5789473684211, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790519, Length=311, Percent_Identity=29.2604501607717, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081951, Length=339, Percent_Identity=23.0088495575221, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790024, Length=240, Percent_Identity=26.25, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790012, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787013, Length=349, Percent_Identity=26.0744985673352, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37320; Mature: 37188

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKLIIAVPLILAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVISDVT
CCCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECEEEEEECCCEEEEEECC
DNQHVRKGELLAQLEDNQFSAKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AQADKLRAEQQLTRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKALLVAKERELAVF
EHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCHHHCCHHHHHEEEEECCCCEEEE
NAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECHHHHCCCHHHCCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSEEEARVVPGLSAVVKVDTASHPTTAIAANVGR
CHHHHHHHHCCEEEEEECCCCCHHCCCCCEEEEEEECCCCCCEEEEECCCC
>Mature Secondary Structure 
SKSKLIIAVPLILAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVISDVT
CCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECEEEEEECCCEEEEEECC
DNQHVRKGELLAQLEDNQFSAKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AQADKLRAEQQLTRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKALLVAKERELAVF
EHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCHHHCCHHHHHEEEEECCCCEEEE
NAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECHHHHCCCHHHCCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSEEEARVVPGLSAVVKVDTASHPTTAIAANVGR
CHHHHHHHHCCEEEEEECCCCCHHCCCCCEEEEEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]