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The map label for this gene is fieF [H]

Identifier: 113968599

GI number: 113968599

Start: 273103

End: 273996

Strand: Direct

Name: fieF [H]

Synonym: Shewmr4_0254

Alternate gene names: 113968599

Gene position: 273103-273996 (Clockwise)

Preceding gene: 113968598

Following gene: 113968600

Centisome position: 5.8

GC content: 51.45

Gene sequence:

>894_bases
ATGACTCAAACTTCCCAATACGATTTTTGGGTCAAACTGGCTAGTCGCGCTTCCGTGGCTACCGCTTTGACCCTTATTAT
TATCAAGCTATTAGCTTGGTTATATTCAGGCTCGGCCAGTATGCTGGCGTCCTTAACGGACTCCTTTGCCGATGCGCTCG
CCTCGATCATCAACTTTATCGCCATTCGTTATGCTATCGTTCCTGCCGACCATGACCACAGATACGGCCACGGTAAGGCC
GAGCCGTTAGCGTCGCTGGCACAATCGGCCTTTATCATGGGCTCGGCATTCCTGCTGCTGTTTTATGGCGGAGAACGCTT
ACTCAATCCTGCTCCCGTTGAATATGCCACCTTAGGTGTGGTGGTGTCTGTCGTTGCGATCGTGCTGACATTGGCGTTAG
TGGCGTTACAAAAGCGGGCGCTGGCGGCAACCAAGAGCACTGTGGTTGAAGCCGATTCGTTGCACTACAAGTCGGATTTA
TTCCTCAATGGCGCCGTGTTACTCGCACTCCTTTTGTCCCAGTATGGCTGGTGGTGGGCCGATGGGGTCTTTGCCGTGCT
TATCGCCTGCTACATTGGTCAACAGGCCTTTGATTTAGGTTACCGCTCTATTCAAGCGCTGCTCGACCGTGAGTTAGATG
AAGAGACGCGTCAGCAAATTAAGCAAATCGCCAAGCAAGATCCTAGAGTGCAAGGGCTACATGATTTACGCACGCGCCAA
GCGGGTAAAACCATCTTTATTCAATTCCATTTAGAGTTAGATGGTAACCTGAGCCTGAACGAAGCCCACAGTATCGCCGA
TACTACAGGGCTCAGAGTAAAAGCCGCCTTTGAAGATGCCGAGGTGATTATTCACCAAGATCCTGTGCAGGTGGAGCCTA
GCCCCGCGAGTTAA

Upstream 100 bases:

>100_bases
AATTTAAAGCGCGATTTGAAGCACAAGCTGGTAAAGAACCTCGCGGTTAAGCTTGTAAGCTGATATACAATAGAGTCATA
GCTTCCCGATATAGACCCCT

Downstream 100 bases:

>100_bases
TCATCGCGGTCAATTGAGTTTGTTATAAAAACCAAAGGAATGGTTATGTCATGGATGCAGCAACAGGTTCATCCCTTAGT
CGACAATACTCGGCTTATCT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEYATLGVVVSVVAIVLTLALVALQKRALAATKSTVVEADSLHYKSDL
FLNGAVLLALLLSQYGWWWADGVFAVLIACYIGQQAFDLGYRSIQALLDRELDEETRQQIKQIAKQDPRVQGLHDLRTRQ
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSPAS

Sequences:

>Translated_297_residues
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEYATLGVVVSVVAIVLTLALVALQKRALAATKSTVVEADSLHYKSDL
FLNGAVLLALLLSQYGWWWADGVFAVLIACYIGQQAFDLGYRSIQALLDRELDEETRQQIKQIAKQDPRVQGLHDLRTRQ
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSPAS
>Mature_296_residues
TQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKAE
PLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEYATLGVVVSVVAIVLTLALVALQKRALAATKSTVVEADSLHYKSDLF
LNGAVLLALLLSQYGWWWADGVFAVLIACYIGQQAFDLGYRSIQALLDRELDEETRQQIKQIAKQDPRVQGLHDLRTRQA
GKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSPAS

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=248, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790349, Length=269, Percent_Identity=49.0706319702602, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI115533508, Length=271, Percent_Identity=23.9852398523985, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533506, Length=271, Percent_Identity=23.9852398523985, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32456; Mature: 32324

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIINFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADHDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEYATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHH
VVSVVAIVLTLALVALQKRALAATKSTVVEADSLHYKSDLFLNGAVLLALLLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHH
DGVFAVLIACYIGQQAFDLGYRSIQALLDRELDEETRQQIKQIAKQDPRVQGLHDLRTRQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSPAS
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIINFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADHDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEYATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHH
VVSVVAIVLTLALVALQKRALAATKSTVVEADSLHYKSDLFLNGAVLLALLLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHH
DGVFAVLIACYIGQQAFDLGYRSIQALLDRELDEETRQQIKQIAKQDPRVQGLHDLRTRQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSPAS
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA