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The map label for this gene is acoR [H]

Identifier: 113968595

GI number: 113968595

Start: 268246

End: 270105

Strand: Direct

Name: acoR [H]

Synonym: Shewmr4_0250

Alternate gene names: 113968595

Gene position: 268246-270105 (Clockwise)

Preceding gene: 113968593

Following gene: 113968598

Centisome position: 5.7

GC content: 53.01

Gene sequence:

>1860_bases
ATGACAGTAAAACCGCATTTTCCAACCACACAGGCATGGTTAGCCGATTCATGGCAACGCAGCTTAGGTGCTGGCTTATC
AGAGTTTCGTGCTGGTGAGGATCTCAGACTCACGCGCGCGGAGCTCAAACATAAACATGAGAAATATCAGCAGCTCATCG
AATTAGTACAATCCCATGCCTTGCCGCTGTTTAATCAACTGATGGCGCACTCCAATAGTCGATTATTGCTCTCCGATGCC
GACGGTTATGTGCTGAAACATTGGGGGGTGAGCCGCTATTCCAGCAAGCTGGCGGATGTGGCGCTCGATATTGGGGTCAA
CTGGCTCGAAAAGTATAAGGGCACTAATGCAATAGGCACGGCGCTCACGGCCAAACAGGCGGTATCAGTGGTTGGCGAGC
AGCATTTTATCCGCCAAAACCGTTTTATGAGTTGCACCGCTTGCCCGATTTTTTCGCCCCAAGGCGAGATGCTCGGAGTG
CTCGATATTACCAGTGAGCAGCAGCGGCATTCGCAGCAAACCTTGATGCTAGTGTCGAGTTTGGCGCAGCAGGTCGAAAC
GGCGCTGCTGTGTCATCTGCCCGGTAGTCATTATCGAATCGATTTCGCGGCGCAGCCGAGTCTATTAAATTCAGGTTGGC
AAGGTATAGTCATCGCCAGCAGTGACGGGCGAATTGTGGGCTGTAATCCCATGGCTAAACAACTGCTGAGCCAAGCAAAG
TTGGGGGACAGTTTAGAGCAACACCTCGGCGACAATTGGGCGCGAGCGGGGGGCTTTCACCGCGATTCGGCGCTGCATGT
GCAGACGCAAGCACTCGCACTGACACAGACGAAAAGTACTAGAACCCTTCAAGACAAACCCTCGAACCAATTGGGGGTCA
GGTTTCGCGACCCGCTATTGGAGCGGGCCTGGCAGCAAGCGAATAAGGTGATTACTAAGCAGATCCCCCTACTGGTGCTT
GGCGAAACGGGTGTCGGCAAGGAGCAATTTGTGAAAAAGCTCCACGCCCAGAGTGCCCGCCGCGCGCAGCCCTTGGTGGC
GGTAAACTGCGCCGCCTTGCCTGCTGAGTTAGTTGAGTCTGAGTTATTTGGTTATCAGGCGGGGGCTTTTACTGGCGCTA
ATAGAACCGGTTTTATCGGTAAGATCCGCCAAGCCCACGGTGGCTTTTTGTTCCTCGATGAAATTGGTGAGATGCCGCTG
GCGGCGCAGAGTCGTTTACTCCGCGTGTTGCAGGAGCGTGAGGTCGTTCCCGTCGGCAGTAATCAAAGTTTTAAGGTCGA
TATTCAGATCATCGCCGCGACCCATATGGATTTAGAGTCGCTGGTGGCACAGGGATTGTTCCGTCAGGACTTGTTTTATC
GCCTAAATGGATTGCAAGTGCGGCTTCCTGCACTGCGTGAACGGCAGGATATTGAGCGCATCATCCATAAATTGCACCGC
CGTCACCGCAGTAGCGCGCAAACCTTGTGTACTGAGTTGTTGGCGCAGCTAATGCGTTACGATTGGCCCGGCAACCTAAG
GGAGCTGGATAACCTAATGCAGGTGGCGTGTTTGATGGCTGAAGGTGAGGCCGTACTCGAGATAAATCATCTCCCCGATT
ACCTTGCTCAAAAGCTCATGAATCTGGCGTTTGAGCCCCAAACTTTAACTGAAGTTGTCGACGCCGAAACCACGGCGCAT
CCGCACGAACTGTCCGAGTCTAGCTCTACGACTATAGACTCGCTCCACGGAACCATAAATCTGAACGTGTTACAGGCTTA
TCGTGCCTGCGAGGGCAATGTGAGTCAGTGCGCTAAGCGTTTAGGGATCAGCCGTAATGCCTTGTATCGCAAGTTAAAAC
AGCTAGGGGTTAAGGACTAA

Upstream 100 bases:

>100_bases
TAGGGGCACTCACGGAAGGAAAGGTGCCCTGTGGTCATTTTGTCATCCAACGACACACCATGGGTGTGCCGAAATGGAAC
AGCGCTCGGGGAGCATGGCT

Downstream 100 bases:

>100_bases
CGGCAGTTGACTGTTGATGATATAAGCCCCGCTAACGGAGTTAGCGGGGCTTATGTTTTTAGGTCGGTAAACTGATATTG
ACTTCGAGGCCGTGGGGCTG

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MTVKPHFPTTQAWLADSWQRSLGAGLSEFRAGEDLRLTRAELKHKHEKYQQLIELVQSHALPLFNQLMAHSNSRLLLSDA
DGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
LDITSEQQRHSQQTLMLVSSLAQQVETALLCHLPGSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPMAKQLLSQAK
LGDSLEQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLLERAWQQANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
RHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLAFEPQTLTEVVDAETTAH
PHELSESSSTTIDSLHGTINLNVLQAYRACEGNVSQCAKRLGISRNALYRKLKQLGVKD

Sequences:

>Translated_619_residues
MTVKPHFPTTQAWLADSWQRSLGAGLSEFRAGEDLRLTRAELKHKHEKYQQLIELVQSHALPLFNQLMAHSNSRLLLSDA
DGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
LDITSEQQRHSQQTLMLVSSLAQQVETALLCHLPGSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPMAKQLLSQAK
LGDSLEQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLLERAWQQANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
RHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLAFEPQTLTEVVDAETTAH
PHELSESSSTTIDSLHGTINLNVLQAYRACEGNVSQCAKRLGISRNALYRKLKQLGVKD
>Mature_618_residues
TVKPHFPTTQAWLADSWQRSLGAGLSEFRAGEDLRLTRAELKHKHEKYQQLIELVQSHALPLFNQLMAHSNSRLLLSDAD
GYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVL
DITSEQQRHSQQTLMLVSSLAQQVETALLCHLPGSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPMAKQLLSQAKL
GDSLEQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLLERAWQQANKVITKQIPLLVLG
ETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLA
AQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHRR
HRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLAFEPQTLTEVVDAETTAHP
HELSESSSTTIDSLHGTINLNVLQAYRACEGNVSQCAKRLGISRNALYRKLKQLGVKD

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=499, Percent_Identity=32.064128256513, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1790437, Length=332, Percent_Identity=37.3493975903614, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=41.6167664670659, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788905, Length=327, Percent_Identity=37.9204892966361, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=38.2262996941896, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788550, Length=325, Percent_Identity=39.6923076923077, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1786524, Length=403, Percent_Identity=35.7320099255583, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1789087, Length=322, Percent_Identity=37.5776397515528, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787583, Length=327, Percent_Identity=35.474006116208, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87082152, Length=334, Percent_Identity=35.6287425149701, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081872, Length=205, Percent_Identity=41.9512195121951, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=252, Percent_Identity=37.3015873015873, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081858, Length=332, Percent_Identity=28.6144578313253, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68888; Mature: 68757

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKPHFPTTQAWLADSWQRSLGAGLSEFRAGEDLRLTRAELKHKHEKYQQLIELVQSHA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVLDITSEQQRHSQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LAQQVETALLCHLPGSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPMAKQLLSQAK
HHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
LGDSLEQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLL
CCHHHHHHCCCCHHHCCCCCCCCEEEEEHHHHEEECCCCCCCCCCCCCCCCCCEEHHHHH
ERAWQQANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
RHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
NLAFEPQTLTEVVDAETTAHPHELSESSSTTIDSLHGTINLNVLQAYRACEGNVSQCAKR
HHCCCCHHHHHHHHCCCCCCCHHHCCCCCCHHHHHCCEEEHHHHHHHHHCCCCHHHHHHH
LGISRNALYRKLKQLGVKD
HCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVKPHFPTTQAWLADSWQRSLGAGLSEFRAGEDLRLTRAELKHKHEKYQQLIELVQSHA
CCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVLDITSEQQRHSQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LAQQVETALLCHLPGSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPMAKQLLSQAK
HHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
LGDSLEQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLL
CCHHHHHHCCCCHHHCCCCCCCCEEEEEHHHHEEECCCCCCCCCCCCCCCCCCEEHHHHH
ERAWQQANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
RHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
NLAFEPQTLTEVVDAETTAHPHELSESSSTTIDSLHGTINLNVLQAYRACEGNVSQCAKR
HHCCCCHHHHHHHHCCCCCCCHHHCCCCCCHHHHHCCEEEHHHHHHHHHCCCCHHHHHHH
LGISRNALYRKLKQLGVKD
HCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]