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The map label for this gene is tlpA [H]

Identifier: 113968582

GI number: 113968582

Start: 252354

End: 252935

Strand: Direct

Name: tlpA [H]

Synonym: Shewmr4_0237

Alternate gene names: 113968582

Gene position: 252354-252935 (Clockwise)

Preceding gene: 113968581

Following gene: 113968583

Centisome position: 5.36

GC content: 45.88

Gene sequence:

>582_bases
ATGAAGTCATTTGCCTTAGCTGCAATCCTAGCGAGTCTGTCTGTTGCCTTTGCTGGTGGTGCCCAAGCGTACCCCGGCAT
GCAGCAGGCAAATAAGCCGATAGAGTCGACAGTCGATCTGATTAACGTTTTGCCAAAAACTTATCCTATCGAACCCGTTG
CTTTTAGTGACGTCGATGGCAAGCCGCTCGATTTCAGTCAATATAAAGGCAAAATCGTGATGGTGAACATGTGGGCGACT
TGGTGTCCTCCCTGTGTCAGAGAGTTACCTGCGATTGAACGATTGGCGACAAAGTTTAAAGCGGAAGAGTTTGCACTATT
ACCTATCTCTATCGATGCGGATGGCAAACAGCAGGTTCAGCCGTTTTTAACTTCATTAGGAATGGCGAACTTTAACTCCT
ACTACGATCCTGAACAAAACCTCGGACAAGTGTTTCCATTAGATACTATCCCCGCGACCTTTATTCTCGATCAAAACGGC
CAATTGATCGCATTTGTGCGATCATTTGTCGACTGGGATGACGCAAAAGCCGTATCACTGATCCAAGGTTTTATCGATAA
AGGCGCGAAAAAGCTGAATTAA

Upstream 100 bases:

>100_bases
TCATCTTTATCCGCAAGCAACGCATCGGTGGCACGACCGAGCCTGAGATCAGCGCCGAAGATCAAAAAGCGCTGGATGCT
CTATTAAAGCGTGATAATAA

Downstream 100 bases:

>100_bases
GCAGCAGATTGCGCGTAAATAGAACGCCGTTGTAGAAAAGATCGCCATGCGATCTTTTTTCTTTTAAAAAGCCCTTGCAC
AAAAAGTTCTGCCGCCTATA

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKSFALAAILASLSVAFAGGAQAYPGMQQANKPIESTVDLINVLPKTYPIEPVAFSDVDGKPLDFSQYKGKIVMVNMWAT
WCPPCVRELPAIERLATKFKAEEFALLPISIDADGKQQVQPFLTSLGMANFNSYYDPEQNLGQVFPLDTIPATFILDQNG
QLIAFVRSFVDWDDAKAVSLIQGFIDKGAKKLN

Sequences:

>Translated_193_residues
MKSFALAAILASLSVAFAGGAQAYPGMQQANKPIESTVDLINVLPKTYPIEPVAFSDVDGKPLDFSQYKGKIVMVNMWAT
WCPPCVRELPAIERLATKFKAEEFALLPISIDADGKQQVQPFLTSLGMANFNSYYDPEQNLGQVFPLDTIPATFILDQNG
QLIAFVRSFVDWDDAKAVSLIQGFIDKGAKKLN
>Mature_193_residues
MKSFALAAILASLSVAFAGGAQAYPGMQQANKPIESTVDLINVLPKTYPIEPVAFSDVDGKPLDFSQYKGKIVMVNMWAT
WCPPCVRELPAIERLATKFKAEEFALLPISIDADGKQQVQPFLTSLGMANFNSYYDPEQNLGQVFPLDTIPATFILDQNG
QLIAFVRSFVDWDDAKAVSLIQGFIDKGAKKLN

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21167; Mature: 21167

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFALAAILASLSVAFAGGAQAYPGMQQANKPIESTVDLINVLPKTYPIEPVAFSDVDG
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCCCC
KPLDFSQYKGKIVMVNMWATWCPPCVRELPAIERLATKFKAEEFALLPISIDADGKQQVQ
CCCCHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
PFLTSLGMANFNSYYDPEQNLGQVFPLDTIPATFILDQNGQLIAFVRSFVDWDDAKAVSL
HHHHHHCHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHH
IQGFIDKGAKKLN
HHHHHHHHHHCCC
>Mature Secondary Structure
MKSFALAAILASLSVAFAGGAQAYPGMQQANKPIESTVDLINVLPKTYPIEPVAFSDVDG
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCCCC
KPLDFSQYKGKIVMVNMWATWCPPCVRELPAIERLATKFKAEEFALLPISIDADGKQQVQ
CCCCHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
PFLTSLGMANFNSYYDPEQNLGQVFPLDTIPATFILDQNGQLIAFVRSFVDWDDAKAVSL
HHHHHHCHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHH
IQGFIDKGAKKLN
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]