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The map label for this gene is murB [H]

Identifier: 113968526

GI number: 113968526

Start: 207421

End: 208476

Strand: Direct

Name: murB [H]

Synonym: Shewmr4_0181

Alternate gene names: 113968526

Gene position: 207421-208476 (Clockwise)

Preceding gene: 113968524

Following gene: 113968527

Centisome position: 4.41

GC content: 47.54

Gene sequence:

>1056_bases
ATGTCGCTTTTGTCGCGGCAGAACATCACCATGTCTTTTCCATATTCGCTAAAGCCGTTTAATACTTTTGGCGTGGAGCA
ATCTTGCTTATCCATGATTGAAGTCCATTCCAAGGCAGAGCTGCAATCGACCTGCTTATCCTTATATCAGTCTAAGCGAC
CTATGCTTGTCCTCGGTGGCGGCAGCAATATCGTATTCACCGATGATTTTAATGGCACTGTAGTGCGTGTGTTGACTAAG
GGTATTTCCTGCTCTGAAGATGGCACTCACTTTTACCTTGCCGTTGAGGCGGGTGAGAACTGGCATGAATTAGTTCACTT
CAGCTTAAATCAGGACATGCCAGGTCTTGAGAACTTAGCGCTTATCCCTGGCACTGTTGGTGCTGCTCCGATCCAAAACA
TCGGCGCCTATGGCGTAGAGCTGTGCGATATTTGTGATTGGGTCGAATATCTGGATCTCGAGTCTGGTAACTTGCTAAGG
CTTACTGCAGATGAGTGTGAGTTTGCCTATCGGGAGTCAATATTTAAGGGCTGTTTACGCGACAAAGCTGTGATTACTGC
CGTTGGTTTGCGCCTCCCTAAAGCTTGGCAACCAAAATTGGCCTATGGTCCGTTACAATCATTTAACGCCGAGACGGTGA
CCCCAAGGGAGATTTTTGAACGAGTCTGCGAAGTGAGGAGCGAAAAGCTACCTAACCCAGAAGAACTCGGAAATGCAGGT
AGTTTCTTTAAGAATCCTATCGTAAGCGCGGCGACTTATATGCAGCTTGCTGCGCATTTCCCGAGTATCGTCGGTTATGC
GCAACCCAATGGAGAGGTTAAACTGGCTGCAGGTTGGCTAATCGAACATGCGGGTCTTAAGGGTTTTGCTCTTGGTAACG
CGGGAGTGCATGCGAAGCAAGCCTTAGTATTAGTCAATTTAGGTCATGCGACCGGCCAAGATATTTGTCGATTAGCATTA
CATGTTATTGCGCGAGTGAATGAGGTTTTTGGCGTTAAGCTAGAAGCCGAGCCAAGAATTATGGGATTAACAGGGGAGAC
GAGTCTCGATGTCTGA

Upstream 100 bases:

>100_bases
CTCTGTTGTTTTTACTCTTGTTCAAGACCTTACTGCATTAATTTACCTGCTTTTACCGATCTACCTCAGTTTGCTGCAAT
TCTAGGGTGAAGCGTTTACA

Downstream 100 bases:

>100_bases
TAACTGGGTGAGAAAACGCGAAATACTGGGATTACTGTCGAGCGAATATTTTGTCTCGGGTGAAGAGTTGGCGACACAAC
TGGGTATTTCTCGTGCGGCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSLLSRQNITMSFPYSLKPFNTFGVEQSCLSMIEVHSKAELQSTCLSLYQSKRPMLVLGGGSNIVFTDDFNGTVVRVLTK
GISCSEDGTHFYLAVEAGENWHELVHFSLNQDMPGLENLALIPGTVGAAPIQNIGAYGVELCDICDWVEYLDLESGNLLR
LTADECEFAYRESIFKGCLRDKAVITAVGLRLPKAWQPKLAYGPLQSFNAETVTPREIFERVCEVRSEKLPNPEELGNAG
SFFKNPIVSAATYMQLAAHFPSIVGYAQPNGEVKLAAGWLIEHAGLKGFALGNAGVHAKQALVLVNLGHATGQDICRLAL
HVIARVNEVFGVKLEAEPRIMGLTGETSLDV

Sequences:

>Translated_351_residues
MSLLSRQNITMSFPYSLKPFNTFGVEQSCLSMIEVHSKAELQSTCLSLYQSKRPMLVLGGGSNIVFTDDFNGTVVRVLTK
GISCSEDGTHFYLAVEAGENWHELVHFSLNQDMPGLENLALIPGTVGAAPIQNIGAYGVELCDICDWVEYLDLESGNLLR
LTADECEFAYRESIFKGCLRDKAVITAVGLRLPKAWQPKLAYGPLQSFNAETVTPREIFERVCEVRSEKLPNPEELGNAG
SFFKNPIVSAATYMQLAAHFPSIVGYAQPNGEVKLAAGWLIEHAGLKGFALGNAGVHAKQALVLVNLGHATGQDICRLAL
HVIARVNEVFGVKLEAEPRIMGLTGETSLDV
>Mature_350_residues
SLLSRQNITMSFPYSLKPFNTFGVEQSCLSMIEVHSKAELQSTCLSLYQSKRPMLVLGGGSNIVFTDDFNGTVVRVLTKG
ISCSEDGTHFYLAVEAGENWHELVHFSLNQDMPGLENLALIPGTVGAAPIQNIGAYGVELCDICDWVEYLDLESGNLLRL
TADECEFAYRESIFKGCLRDKAVITAVGLRLPKAWQPKLAYGPLQSFNAETVTPREIFERVCEVRSEKLPNPEELGNAGS
FFKNPIVSAATYMQLAAHFPSIVGYAQPNGEVKLAAGWLIEHAGLKGFALGNAGVHAKQALVLVNLGHATGQDICRLALH
VIARVNEVFGVKLEAEPRIMGLTGETSLDV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=50.2994011976048, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38233; Mature: 38102

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSRQNITMSFPYSLKPFNTFGVEQSCLSMIEVHSKAELQSTCLSLYQSKRPMLVLGG
CCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GSNIVFTDDFNGTVVRVLTKGISCSEDGTHFYLAVEAGENWHELVHFSLNQDMPGLENLA
CCEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHEEEECCCCCCCCCCEE
LIPGTVGAAPIQNIGAYGVELCDICDWVEYLDLESGNLLRLTADECEFAYRESIFKGCLR
ECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
DKAVITAVGLRLPKAWQPKLAYGPLQSFNAETVTPREIFERVCEVRSEKLPNPEELGNAG
CHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCC
SFFKNPIVSAATYMQLAAHFPSIVGYAQPNGEVKLAAGWLIEHAGLKGFALGNAGVHAKQ
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEHHCCCCEEEECCCCCCCCE
ALVLVNLGHATGQDICRLALHVIARVNEVFGVKLEAEPRIMGLTGETSLDV
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCCC
>Mature Secondary Structure 
SLLSRQNITMSFPYSLKPFNTFGVEQSCLSMIEVHSKAELQSTCLSLYQSKRPMLVLGG
CCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GSNIVFTDDFNGTVVRVLTKGISCSEDGTHFYLAVEAGENWHELVHFSLNQDMPGLENLA
CCEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHEEEECCCCCCCCCCEE
LIPGTVGAAPIQNIGAYGVELCDICDWVEYLDLESGNLLRLTADECEFAYRESIFKGCLR
ECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
DKAVITAVGLRLPKAWQPKLAYGPLQSFNAETVTPREIFERVCEVRSEKLPNPEELGNAG
CHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCC
SFFKNPIVSAATYMQLAAHFPSIVGYAQPNGEVKLAAGWLIEHAGLKGFALGNAGVHAKQ
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEHHCCCCEEEECCCCCCCCE
ALVLVNLGHATGQDICRLALHVIARVNEVFGVKLEAEPRIMGLTGETSLDV
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA