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The map label for this gene is dgdR [H]

Identifier: 113968352

GI number: 113968352

Start: 7124

End: 7972

Strand: Direct

Name: dgdR [H]

Synonym: Shewmr4_0006

Alternate gene names: 113968352

Gene position: 7124-7972 (Clockwise)

Preceding gene: 113968350

Following gene: 113968353

Centisome position: 0.15

GC content: 47.82

Gene sequence:

>849_bases
ATGGATATAGAAGCGCTGCGCAGCTTTGTGGCATTTGTCGATACCGGGAGTTTTACCCGCGCGGCAATGCAAACCTATAA
GACTCAATCTGCCGTCAGTATGCAAATGAAGCGCTTAGAGCAAGAGCTGGGAAAAACGCTCTTTGTAAAAGAGGGGCGAA
ACTTAGTCTTATCTACCGAAGGCCAACGTTTTGGCTTATACGCTAAGCAATTACTGCAACTACACGATGAGACTGTCACA
ACCATTAAGCAGACTCAAGTCGGCACGCAATTGCATTTAGGTTGTCCCGATGACTATGCCGAATCCGTGTTACCGCGGAT
AGTGGCGTTGTTACATGGTCACATTAAGCAACTCGATCTTCAAATTACTTGCGCCTCAAGCCAAAAGCTGCGGATCATGC
TGGATACCGGGCAACTCGATGCGGCGATAGTGACTCGTTTGCCCGAGTCCGATGAAGGCTACTTATTACAAACCTCGAAA
GGCGTTTGGGTGAGCGCGAGTGGTTCGAACTTGAGTGATGCCGATCCGTTACCCATAGCGCTTTTCCAAAAGGATTGTAA
ATTCCATATTGCGGCGTTAGATGGATTGATGAAGCAAGATAGGCATTATCAGTTGTTGGCCTGTAGCAGCAGTGCTGCGG
CTCTTAAAGCGATAGTGGCTAAGGATTTGGCTATTAGTGCCATGGCTGAATGCAGTGTATCGGCATCACTGAATATTATT
GATTCTGAAACACTTCCACCCTTGCCTGTGGTCGCCGTCGCACTGGTTATTTCCGCTAAAGCTTACTCACCCATAAATGC
GGAGTTGGCCAAGCAAATTGCGCGGGGCTATCAAAGCTACTTGGAATAA

Upstream 100 bases:

>100_bases
TTATCAATATAGGCGCTTGTACTTTGCATGACTAACGAATAGATTTGATGTTATCTATCAGCAAAATGAATAGATAGACT
GACATCAGATAGGAAACATG

Downstream 100 bases:

>100_bases
GGTTTCACGTGAAACAATTTAATGATCTAACGCAGCCTTAAGCTTGAGGGCATATACTAAAACGGCGCGTTATACGAATA
GCCTCGCATATCAAAGACAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MDIEALRSFVAFVDTGSFTRAAMQTYKTQSAVSMQMKRLEQELGKTLFVKEGRNLVLSTEGQRFGLYAKQLLQLHDETVT
TIKQTQVGTQLHLGCPDDYAESVLPRIVALLHGHIKQLDLQITCASSQKLRIMLDTGQLDAAIVTRLPESDEGYLLQTSK
GVWVSASGSNLSDADPLPIALFQKDCKFHIAALDGLMKQDRHYQLLACSSSAAALKAIVAKDLAISAMAECSVSASLNII
DSETLPPLPVVAVALVISAKAYSPINAELAKQIARGYQSYLE

Sequences:

>Translated_282_residues
MDIEALRSFVAFVDTGSFTRAAMQTYKTQSAVSMQMKRLEQELGKTLFVKEGRNLVLSTEGQRFGLYAKQLLQLHDETVT
TIKQTQVGTQLHLGCPDDYAESVLPRIVALLHGHIKQLDLQITCASSQKLRIMLDTGQLDAAIVTRLPESDEGYLLQTSK
GVWVSASGSNLSDADPLPIALFQKDCKFHIAALDGLMKQDRHYQLLACSSSAAALKAIVAKDLAISAMAECSVSASLNII
DSETLPPLPVVAVALVISAKAYSPINAELAKQIARGYQSYLE
>Mature_282_residues
MDIEALRSFVAFVDTGSFTRAAMQTYKTQSAVSMQMKRLEQELGKTLFVKEGRNLVLSTEGQRFGLYAKQLLQLHDETVT
TIKQTQVGTQLHLGCPDDYAESVLPRIVALLHGHIKQLDLQITCASSQKLRIMLDTGQLDAAIVTRLPESDEGYLLQTSK
GVWVSASGSNLSDADPLPIALFQKDCKFHIAALDGLMKQDRHYQLLACSSSAAALKAIVAKDLAISAMAECSVSASLNII
DSETLPPLPVVAVALVISAKAYSPINAELAKQIARGYQSYLE

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=282, Percent_Identity=30.8510638297872, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787806, Length=237, Percent_Identity=24.0506329113924, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI48994962, Length=156, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=155, Percent_Identity=28.3870967741935, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790399, Length=154, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30657; Mature: 30657

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIEALRSFVAFVDTGSFTRAAMQTYKTQSAVSMQMKRLEQELGKTLFVKEGRNLVLSTE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECC
GQRFGLYAKQLLQLHDETVTTIKQTQVGTQLHLGCPDDYAESVLPRIVALLHGHIKQLDL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEEE
QITCASSQKLRIMLDTGQLDAAIVTRLPESDEGYLLQTSKGVWVSASGSNLSDADPLPIA
EEEECCCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHH
LFQKDCKFHIAALDGLMKQDRHYQLLACSSSAAALKAIVAKDLAISAMAECSVSASLNII
EEHHCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DSETLPPLPVVAVALVISAKAYSPINAELAKQIARGYQSYLE
ECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIEALRSFVAFVDTGSFTRAAMQTYKTQSAVSMQMKRLEQELGKTLFVKEGRNLVLSTE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECC
GQRFGLYAKQLLQLHDETVTTIKQTQVGTQLHLGCPDDYAESVLPRIVALLHGHIKQLDL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEEE
QITCASSQKLRIMLDTGQLDAAIVTRLPESDEGYLLQTSKGVWVSASGSNLSDADPLPIA
EEEECCCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHH
LFQKDCKFHIAALDGLMKQDRHYQLLACSSSAAALKAIVAKDLAISAMAECSVSASLNII
EEHHCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DSETLPPLPVVAVALVISAKAYSPINAELAKQIARGYQSYLE
ECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]