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The map label for this gene is kefB2 [H]

Identifier: 116696447

GI number: 116696447

Start: 2838388

End: 2839605

Strand: Direct

Name: kefB2 [H]

Synonym: H16_B2511

Alternate gene names: 116696447

Gene position: 2838388-2839605 (Clockwise)

Preceding gene: 116696446

Following gene: 116696449

Centisome position: 97.46

GC content: 69.95

Gene sequence:

>1218_bases
ATGAACGGGGTCAGCATCTTCTTCCTGCAGGCGATGCTGGTGGTCGCCCTGCCCTATCTGCTATGGCGTGGTGCCGGCCT
GCGCTCGGTGTTTCCGCTGGTTGGTGTGCAGGTGCTGGCCGGCATCGTGCTGGGGCCGTCGGTGTTCGGGCAACTGGCGC
CGCAGGGCTGGACCGCGCTGTTCGGCCCTGATCGCCTGCCGATGCTGTCCGGCCTGCAGTGGCTGGCGGTGACGCTGTTC
TGCTTCCTGACCGGCCTGCACCTGCGCGAAGACAGCGTGCCCGCGCACTGGCGCGCGACCCTGCAGATCTCGCTGGGCAG
CATTGCGGCGCCGTTCGCGCTGGGGGCCGCTGCCGGCTGGTGGATGACCACGGCCGGCTGGCCGGTCGCGGGGGAACTGG
CCAGCCCCTACTGGTTTGCCTGCGCCATGGGCATCTGCACCGCCGTCACGGCGCTGCCGGTGCTGGGTGCGCTGCTGCGC
GAGATGCGCCTGACCGGCACCCGCCTGGGCCAGCTGGCCTTGCGCTGCGCGGCCGTCAACGATGCCTGGGTGTGGCTGTT
CCTGACCCTGGTGCTGCTGCAGCATGGCGGCCAGGACGGCGCCAGCGGCCTCATCGTGGCGGCCCGCGCCGGTGCTTACC
TGGCGTTCATGTTCCTGGCAGTGCGCCCCGCGCTGGCATGGCTGCTGCGCCGCCGCGCGCCGGAGACCGAGCTGCTGCTG
GCGATGGCGCTGTTCCTGGTGCTGGCGTCGGCATTCCTGGGGGAGTTGGCCGGGCTGCACCATGTGATGGGCGGCTTCGT
CGCCGGACTGGTATGGCCCGCACGCGAAGCGCAGCGTGTGCGCCAGCAGCTCGAACCGGTCACGGTGGTGGTGCTGCTGC
CCTTCTTTTTCCTGGCCGCCGGACTGCGCACCGAGATCTCGCTGGATAATCCGATGACACTGTGGATCGCGTTGCTGTCG
CTGGTCATCGCGATCACCGGCAAGATGGCCGGCGTCGCGCTGCCCGCGCGCCGCGCCGGCATGGGCTGGCACGAATCGCT
GGCACTGGGCACGCTACTGCAGACCAAGGGCCTGGTCGAGGTGGTGGTGCTGACCGTGCTGCTGGACGCGCGCATCATCA
GCACCGCGGCGTTTTCCGGACTGTTGCTGATGGCGCTGGCCAGCACGCTGCTGGCGCGGCCGTTGACGATGCTGGTAGCG
CGGGGCCGGTTGCATTAA

Upstream 100 bases:

>100_bases
GCCTTCCTGATGTCGCCCGACGCTGGCTATATCACGCGCCAGGTGATCTCGGTCAACGGGGGCATGTTCGGATGAAGCGC
GTCGTCGCCAGCGTGACCCC

Downstream 100 bases:

>100_bases
GCGCCATCCGGCCGCTCACACCGGAGTCAATCCCGGCAACCCTGCAATCGCCTGCGCCAGGTAGTCCAGCAAAAGCCGCA
CCCGCTCCGGCTGGTAGCGC

Product: Kef-type K+ transport system, membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNGVSIFFLQAMLVVALPYLLWRGAGLRSVFPLVGVQVLAGIVLGPSVFGQLAPQGWTALFGPDRLPMLSGLQWLAVTLF
CFLTGLHLREDSVPAHWRATLQISLGSIAAPFALGAAAGWWMTTAGWPVAGELASPYWFACAMGICTAVTALPVLGALLR
EMRLTGTRLGQLALRCAAVNDAWVWLFLTLVLLQHGGQDGASGLIVAARAGAYLAFMFLAVRPALAWLLRRRAPETELLL
AMALFLVLASAFLGELAGLHHVMGGFVAGLVWPAREAQRVRQQLEPVTVVVLLPFFFLAAGLRTEISLDNPMTLWIALLS
LVIAITGKMAGVALPARRAGMGWHESLALGTLLQTKGLVEVVVLTVLLDARIISTAAFSGLLLMALASTLLARPLTMLVA
RGRLH

Sequences:

>Translated_405_residues
MNGVSIFFLQAMLVVALPYLLWRGAGLRSVFPLVGVQVLAGIVLGPSVFGQLAPQGWTALFGPDRLPMLSGLQWLAVTLF
CFLTGLHLREDSVPAHWRATLQISLGSIAAPFALGAAAGWWMTTAGWPVAGELASPYWFACAMGICTAVTALPVLGALLR
EMRLTGTRLGQLALRCAAVNDAWVWLFLTLVLLQHGGQDGASGLIVAARAGAYLAFMFLAVRPALAWLLRRRAPETELLL
AMALFLVLASAFLGELAGLHHVMGGFVAGLVWPAREAQRVRQQLEPVTVVVLLPFFFLAAGLRTEISLDNPMTLWIALLS
LVIAITGKMAGVALPARRAGMGWHESLALGTLLQTKGLVEVVVLTVLLDARIISTAAFSGLLLMALASTLLARPLTMLVA
RGRLH
>Mature_405_residues
MNGVSIFFLQAMLVVALPYLLWRGAGLRSVFPLVGVQVLAGIVLGPSVFGQLAPQGWTALFGPDRLPMLSGLQWLAVTLF
CFLTGLHLREDSVPAHWRATLQISLGSIAAPFALGAAAGWWMTTAGWPVAGELASPYWFACAMGICTAVTALPVLGALLR
EMRLTGTRLGQLALRCAAVNDAWVWLFLTLVLLQHGGQDGASGLIVAARAGAYLAFMFLAVRPALAWLLRRRAPETELLL
AMALFLVLASAFLGELAGLHHVMGGFVAGLVWPAREAQRVRQQLEPVTVVVLLPFFFLAAGLRTEISLDNPMTLWIALLS
LVIAITGKMAGVALPARRAGMGWHESLALGTLLQTKGLVEVVVLTVLLDARIISTAAFSGLLLMALASTLLARPLTMLVA
RGRLH

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=413, Percent_Identity=30.9927360774818, Blast_Score=173, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 43247; Mature: 43247

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGVSIFFLQAMLVVALPYLLWRGAGLRSVFPLVGVQVLAGIVLGPSVFGQLAPQGWTAL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEC
FGPDRLPMLSGLQWLAVTLFCFLTGLHLREDSVPAHWRATLQISLGSIAAPFALGAAAGW
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCC
WMTTAGWPVAGELASPYWFACAMGICTAVTALPVLGALLREMRLTGTRLGQLALRCAAVN
HHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAWVWLFLTLVLLQHGGQDGASGLIVAARAGAYLAFMFLAVRPALAWLLRRRAPETELLL
HHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALFLVLASAFLGELAGLHHVMGGFVAGLVWPAREAQRVRQQLEPVTVVVLLPFFFLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
GLRTEISLDNPMTLWIALLSLVIAITGKMAGVALPARRAGMGWHESLALGTLLQTKGLVE
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
VVVLTVLLDARIISTAAFSGLLLMALASTLLARPLTMLVARGRLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNGVSIFFLQAMLVVALPYLLWRGAGLRSVFPLVGVQVLAGIVLGPSVFGQLAPQGWTAL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEC
FGPDRLPMLSGLQWLAVTLFCFLTGLHLREDSVPAHWRATLQISLGSIAAPFALGAAAGW
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCC
WMTTAGWPVAGELASPYWFACAMGICTAVTALPVLGALLREMRLTGTRLGQLALRCAAVN
HHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAWVWLFLTLVLLQHGGQDGASGLIVAARAGAYLAFMFLAVRPALAWLLRRRAPETELLL
HHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALFLVLASAFLGELAGLHHVMGGFVAGLVWPAREAQRVRQQLEPVTVVVLLPFFFLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
GLRTEISLDNPMTLWIALLSLVIAITGKMAGVALPARRAGMGWHESLALGTLLQTKGLVE
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
VVVLTVLLDARIISTAAFSGLLLMALASTLLARPLTMLVARGRLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]