| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
Click here to switch to the map view.
The map label for this gene is fabG [H]
Identifier: 116696446
GI number: 116696446
Start: 2837631
End: 2838362
Strand: Direct
Name: fabG [H]
Synonym: H16_B2510
Alternate gene names: 116696446
Gene position: 2837631-2838362 (Clockwise)
Preceding gene: 116696445
Following gene: 116696447
Centisome position: 97.43
GC content: 69.26
Gene sequence:
>732_bases ATGACCAATCCGACCGTACTGGTTACGGGATCGTCGCGCGGCATCGGTCGCGCCATCGCCCTGCGGCTGGCCCGCGACGG CTATGACGTGGTGGTGCATTGCCGCTCGCGCCGCGACGAAGCCGACTCCGTCGCCGACGCGGTGCGCGCTTGCGGCCGCA AGGCCCGCGTGTTGTGCTTCGACGTGGCCCGGCGCGAGGAAGCCGCTGCCGCGCTGCTGGCCGATATCGCCGCACATGAC TGCTACTACGGCGTGGTGTGCAACGCCGGCCTGGCGCGCGACGCGGCCTTCCCGGCCATGAGCGGCGCCGAATGGGACGA GGTGGTGCACACCAACCTCGACGCCTTCTACAACGTGCTCAACCCGGTGGTGATGCCGATGGTGCAGCGACGCCAGCCCG GGCGCATCGTCACGCTGTCGTCGGTCTCGGGCCTGGTGGGCAACCGCGGCCAGACCAACTACAGCGCGGCCAAGGCCGGC ATCATCGGCGCCACCAAGGCGCTGGCAATCGAACTTGCCAAACGCGCCATCACAGTCAACTGCGTGGCGCCCGGCCTGAT CGACACCGACATGGTCGAGCAGCACGTGCGCGACGAGGCGCTGCGCATGATCCCGGCGCGGCGGCTCGGCACGCCCGACG AAGTGGCCGCGACCGTGGCCTTCCTGATGTCGCCCGACGCTGGCTATATCACGCGCCAGGTGATCTCGGTCAACGGGGGC ATGTTCGGATGA
Upstream 100 bases:
>100_bases GCGGTGCTGGAAGAATTCTGCCGCGTATGATGCGCCGCATCTGCACGCGTTCCGCGTTCGCGCCTGCGCCCGCAGAGGAC TTTTTTCAAGGACACCTGGT
Downstream 100 bases:
>100_bases AGCGCGTCGTCGCCAGCGTGACCCCATGAACGGGGTCAGCATCTTCTTCCTGCAGGCGATGCTGGTGGTCGCCCTGCCCT ATCTGCTATGGCGTGGTGCC
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MTNPTVLVTGSSRGIGRAIALRLARDGYDVVVHCRSRRDEADSVADAVRACGRKARVLCFDVARREEAAAALLADIAAHD CYYGVVCNAGLARDAAFPAMSGAEWDEVVHTNLDAFYNVLNPVVMPMVQRRQPGRIVTLSSVSGLVGNRGQTNYSAAKAG IIGATKALAIELAKRAITVNCVAPGLIDTDMVEQHVRDEALRMIPARRLGTPDEVAATVAFLMSPDAGYITRQVISVNGG MFG
Sequences:
>Translated_243_residues MTNPTVLVTGSSRGIGRAIALRLARDGYDVVVHCRSRRDEADSVADAVRACGRKARVLCFDVARREEAAAALLADIAAHD CYYGVVCNAGLARDAAFPAMSGAEWDEVVHTNLDAFYNVLNPVVMPMVQRRQPGRIVTLSSVSGLVGNRGQTNYSAAKAG IIGATKALAIELAKRAITVNCVAPGLIDTDMVEQHVRDEALRMIPARRLGTPDEVAATVAFLMSPDAGYITRQVISVNGG MFG >Mature_242_residues TNPTVLVTGSSRGIGRAIALRLARDGYDVVVHCRSRRDEADSVADAVRACGRKARVLCFDVARREEAAAALLADIAAHDC YYGVVCNAGLARDAAFPAMSGAEWDEVVHTNLDAFYNVLNPVVMPMVQRRQPGRIVTLSSVSGLVGNRGQTNYSAAKAGI IGATKALAIELAKRAITVNCVAPGLIDTDMVEQHVRDEALRMIPARRLGTPDEVAATVAFLMSPDAGYITRQVISVNGGM FG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=39.3574297188755, Blast_Score=139, Evalue=3e-33, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=36.0169491525424, Blast_Score=121, Evalue=6e-28, Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=34.6613545816733, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=32.9411764705882, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=34.136546184739, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=31.9587628865979, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI66933014, Length=201, Percent_Identity=25.8706467661692, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=33.1632653061224, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=29.7520661157025, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=30.2702702702703, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI59889578, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=28.8, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=43.0962343096234, Blast_Score=172, Evalue=1e-44, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.1269841269841, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1788459, Length=239, Percent_Identity=33.8912133891213, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=29.2, Blast_Score=110, Evalue=6e-26, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=34.9794238683128, Blast_Score=110, Evalue=6e-26, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.5785123966942, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=30.8333333333333, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=30.327868852459, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=30.9236947791165, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=28.6259541984733, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=29.7979797979798, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787526, Length=225, Percent_Identity=28.4444444444444, Blast_Score=65, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=35.5102040816327, Blast_Score=130, Evalue=6e-31, Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=34.5833333333333, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=32.1705426356589, Blast_Score=115, Evalue=1e-26, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=30.6451612903226, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.4354838709677, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17568967, Length=249, Percent_Identity=30.1204819277108, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.3650793650794, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.2352941176471, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=29.4339622641509, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=27.9245283018868, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.7566539923954, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=29.5719844357977, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=28.5140562248996, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.6875, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=28.8537549407115, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=26.7175572519084, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=27.5092936802974, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=25.7028112449799, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=30.6451612903226, Blast_Score=94, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=151, Percent_Identity=31.7880794701987, Blast_Score=79, Evalue=8e-16, Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=34.5833333333333, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=35.3658536585366, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=28.7449392712551, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.2, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=30.1652892561983, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=33.1550802139037, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=29.4573643410853, Blast_Score=73, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR011285 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25857; Mature: 25726
Theoretical pI: Translated: 8.12; Mature: 8.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.5 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 5.8 %Cys+Met (Translated Protein) 2.5 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 5.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNPTVLVTGSSRGIGRAIALRLARDGYDVVVHCRSRRDEADSVADAVRACGRKARVLCF CCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEE DVARREEAAAALLADIAAHDCYYGVVCNAGLARDAAFPAMSGAEWDEVVHTNLDAFYNVL HHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHH NPVVMPMVQRRQPGRIVTLSSVSGLVGNRGQTNYSAAKAGIIGATKALAIELAKRAITVN HHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHEEEE CVAPGLIDTDMVEQHVRDEALRMIPARRLGTPDEVAATVAFLMSPDAGYITRQVISVNGG ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCC MFG CCC >Mature Secondary Structure TNPTVLVTGSSRGIGRAIALRLARDGYDVVVHCRSRRDEADSVADAVRACGRKARVLCF CCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEE DVARREEAAAALLADIAAHDCYYGVVCNAGLARDAAFPAMSGAEWDEVVHTNLDAFYNVL HHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHH NPVVMPMVQRRQPGRIVTLSSVSGLVGNRGQTNYSAAKAGIIGATKALAIELAKRAITVN HHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHEEEE CVAPGLIDTDMVEQHVRDEALRMIPARRLGTPDEVAATVAFLMSPDAGYITRQVISVNGG ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCC MFG CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9020051 [H]