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The map label for this gene is yhcK [H]

Identifier: 116696263

GI number: 116696263

Start: 2636417

End: 2637991

Strand: Direct

Name: yhcK [H]

Synonym: H16_B2327

Alternate gene names: 116696263

Gene position: 2636417-2637991 (Clockwise)

Preceding gene: 116696262

Following gene: 116696267

Centisome position: 90.52

GC content: 70.35

Gene sequence:

>1575_bases
ATGCCCTCATATTCCCTGGTTCTCCTGCTTACCGTCGCCGTGGTCGCCTGCATCGGCATGGCCATCGCCACCTGGCCGCG
GCGCGACGATCCGACCGTCCAGGCGTTCCTGGTGCTGGCATTCGGCGCGGCGACCTGGAGCGGCGGCCGCCTGCTCGAGA
TCAGCTCCACGGACCTGGAAGGGCGCATCCTGTGGGCCAAGATCCAGTACCTCGGGATCGTCGCCGTGCCGATCGGTTGG
CTGGTGGCGATGGTGCACCTGAGCCGCCCGCGCTATGTGGTGCCCTGGTCCAGGCTGTGGCTGCCCGTGCTGGTGGCCGT
GGTCACCGTGGTGATGGTCTTCACCAACGAGCGCCACCGGCTGATCTGGCCGCGCATCACGCTGATGCCTCCCGGCGTAC
TGCCCGGTGCGGTGTTCGACCATGGCATCGGCTATGCCGCGGTGGCGGCCTGGTCGTACCTGCTGCTGGGGGTGAGCCTG
CATTTCCTGGTGACGGCCGAAGTGCCCAACGGGGCCTTGTCGCGGCGGGGCCGCGCCATCCTGGCGTCGGGCCTGGCCTT
GCCCCTGGTTGCCAATGTCGCCTACCTCAACCGCTGGACCGGGCCGCTGGGCGGGGACCTGACGCCGGCGACGTTCTCGC
TGATGGCGGCGCTGGTCTGGTTCTGCGCGCTGCGCACGCACCTTGACGATATCGGCCACTACGCCCGCCTGCAGGTGTTC
GATGCCCTCAGCGAGGGCTGCGTGATCGTCGACAGCCATGGCGCCATCGTCGAATTCAACCCGGCCGCCGCGCAGCTTTG
GCCGGCCCTGCGCCGCGGCGACCCACTGCCCTCCGGCTGGGAAACCGCGCTGCAGCACTCGCCTGCCGACACTGCCAGCC
TCGCGGCCACGCCTTTCGTGCCACCGGGCGCGCCCTTCGAGCTTACCGTGGAGCGTGTCGCCCGCCTGGACGGCAGGCAG
ATCGGCAGCCTGCTGTTTTTGCGCGACATCAGCCGCTTCCAGTCGCGCGAGCTGGCCCTGACCGCGCGGCTCGGCCAGAC
CGAAGAGCAGTTGTGGCAGGTGCAGGCCGACCTGGACATCGACGCCCTGACCGGCATCCGCAACCGGCGCTACTTCCAGC
GCGAGTCGATCGCGGCCGTGACCCGGGCGTGCGAGCGCAGCCAGGCGCTGGGCCTGCTGATCCTGGATGTGGACCAGTTC
AAGCAATACAACGACCTGCATGGCCACGTGGCCGGCGACGACTGCCTGCGGCAGATTGCCGGCGCCCTGGCCCGCACGCT
CTCCGGCGAGCAGTTCTGCGCCCGGCTGGGCGGCGAGGAATTCGCGGCGGTGCTGCCCGGCGCCACGCGTGAAGAGACCC
GTGACGTGGCGCGCCGCATGGTGGCCGTTGTGCGCGATCTCGGCATCGCGCACAACGGCACGCCGGTGCAGCCGGTGGTC
ACCATCAGCGTGGGCGCGGTCTGGACCGTGCCGGAAGCGCCGCGGCTGGAGCCGCTGCTGCACCGCGCCGACAGCGCTAT
GTACCGGGCCAAGCGCGCGGGACGCAACCGCTTCATGCTGGACGGCGACGCCTGA

Upstream 100 bases:

>100_bases
CCCACTGCCAAGCCAGCCGCGCAGCCCGGTATCATGCTGGCTGACGAGATCGCGGATCGCCGGAACCAACGCCCGGGTCT
CGGGACGCGCTCCGCCTTCA

Downstream 100 bases:

>100_bases
GCGGCACGGCTACGACGCCGCACCTGCCCGCCCCACGGTGGCGCCGTGCAAGGCCACCAGCCGCGCCGCCGCCTGGCTGA
CCCATGCGGGCCGCGGCGCG

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MPSYSLVLLLTVAVVACIGMAIATWPRRDDPTVQAFLVLAFGAATWSGGRLLEISSTDLEGRILWAKIQYLGIVAVPIGW
LVAMVHLSRPRYVVPWSRLWLPVLVAVVTVVMVFTNERHRLIWPRITLMPPGVLPGAVFDHGIGYAAVAAWSYLLLGVSL
HFLVTAEVPNGALSRRGRAILASGLALPLVANVAYLNRWTGPLGGDLTPATFSLMAALVWFCALRTHLDDIGHYARLQVF
DALSEGCVIVDSHGAIVEFNPAAAQLWPALRRGDPLPSGWETALQHSPADTASLAATPFVPPGAPFELTVERVARLDGRQ
IGSLLFLRDISRFQSRELALTARLGQTEEQLWQVQADLDIDALTGIRNRRYFQRESIAAVTRACERSQALGLLILDVDQF
KQYNDLHGHVAGDDCLRQIAGALARTLSGEQFCARLGGEEFAAVLPGATREETRDVARRMVAVVRDLGIAHNGTPVQPVV
TISVGAVWTVPEAPRLEPLLHRADSAMYRAKRAGRNRFMLDGDA

Sequences:

>Translated_524_residues
MPSYSLVLLLTVAVVACIGMAIATWPRRDDPTVQAFLVLAFGAATWSGGRLLEISSTDLEGRILWAKIQYLGIVAVPIGW
LVAMVHLSRPRYVVPWSRLWLPVLVAVVTVVMVFTNERHRLIWPRITLMPPGVLPGAVFDHGIGYAAVAAWSYLLLGVSL
HFLVTAEVPNGALSRRGRAILASGLALPLVANVAYLNRWTGPLGGDLTPATFSLMAALVWFCALRTHLDDIGHYARLQVF
DALSEGCVIVDSHGAIVEFNPAAAQLWPALRRGDPLPSGWETALQHSPADTASLAATPFVPPGAPFELTVERVARLDGRQ
IGSLLFLRDISRFQSRELALTARLGQTEEQLWQVQADLDIDALTGIRNRRYFQRESIAAVTRACERSQALGLLILDVDQF
KQYNDLHGHVAGDDCLRQIAGALARTLSGEQFCARLGGEEFAAVLPGATREETRDVARRMVAVVRDLGIAHNGTPVQPVV
TISVGAVWTVPEAPRLEPLLHRADSAMYRAKRAGRNRFMLDGDA
>Mature_523_residues
PSYSLVLLLTVAVVACIGMAIATWPRRDDPTVQAFLVLAFGAATWSGGRLLEISSTDLEGRILWAKIQYLGIVAVPIGWL
VAMVHLSRPRYVVPWSRLWLPVLVAVVTVVMVFTNERHRLIWPRITLMPPGVLPGAVFDHGIGYAAVAAWSYLLLGVSLH
FLVTAEVPNGALSRRGRAILASGLALPLVANVAYLNRWTGPLGGDLTPATFSLMAALVWFCALRTHLDDIGHYARLQVFD
ALSEGCVIVDSHGAIVEFNPAAAQLWPALRRGDPLPSGWETALQHSPADTASLAATPFVPPGAPFELTVERVARLDGRQI
GSLLFLRDISRFQSRELALTARLGQTEEQLWQVQADLDIDALTGIRNRRYFQRESIAAVTRACERSQALGLLILDVDQFK
QYNDLHGHVAGDDCLRQIAGALARTLSGEQFCARLGGEEFAAVLPGATREETRDVARRMVAVVRDLGIAHNGTPVQPVVT
ISVGAVWTVPEAPRLEPLLHRADSAMYRAKRAGRNRFMLDGDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787816, Length=188, Percent_Identity=35.1063829787234, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=33.7579617834395, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=36.7469879518072, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788381, Length=300, Percent_Identity=27.6666666666667, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=32.3863636363636, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=35.7541899441341, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=32.3529411764706, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788085, Length=195, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=29.4478527607362, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=193, Percent_Identity=32.6424870466321, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=27.3743016759777, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081977, Length=152, Percent_Identity=30.2631578947368, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 57162; Mature: 57031

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYSLVLLLTVAVVACIGMAIATWPRRDDPTVQAFLVLAFGAATWSGGRLLEISSTDLE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GRILWAKIQYLGIVAVPIGWLVAMVHLSRPRYVVPWSRLWLPVLVAVVTVVMVFTNERHR
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCE
LIWPRITLMPPGVLPGAVFDHGIGYAAVAAWSYLLLGVSLHFLVTAEVPNGALSRRGRAI
EECCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHCCCCH
LASGLALPLVANVAYLNRWTGPLGGDLTPATFSLMAALVWFCALRTHLDDIGHYARLQVF
HHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALSEGCVIVDSHGAIVEFNPAAAQLWPALRRGDPLPSGWETALQHSPADTASLAATPFV
HHHHCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHCCCCCCC
PPGAPFELTVERVARLDGRQIGSLLFLRDISRFQSRELALTARLGQTEEQLWQVQADLDI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCH
DALTGIRNRRYFQRESIAAVTRACERSQALGLLILDVDQFKQYNDLHGHVAGDDCLRQIA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCCCCCCHHHHHHHH
GALARTLSGEQFCARLGGEEFAAVLPGATREETRDVARRMVAVVRDLGIAHNGTPVQPVV
HHHHHHCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TISVGAVWTVPEAPRLEPLLHRADSAMYRAKRAGRNRFMLDGDA
EEEECEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure 
PSYSLVLLLTVAVVACIGMAIATWPRRDDPTVQAFLVLAFGAATWSGGRLLEISSTDLE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GRILWAKIQYLGIVAVPIGWLVAMVHLSRPRYVVPWSRLWLPVLVAVVTVVMVFTNERHR
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCE
LIWPRITLMPPGVLPGAVFDHGIGYAAVAAWSYLLLGVSLHFLVTAEVPNGALSRRGRAI
EECCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHCCCCH
LASGLALPLVANVAYLNRWTGPLGGDLTPATFSLMAALVWFCALRTHLDDIGHYARLQVF
HHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALSEGCVIVDSHGAIVEFNPAAAQLWPALRRGDPLPSGWETALQHSPADTASLAATPFV
HHHHCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHCCCCCCC
PPGAPFELTVERVARLDGRQIGSLLFLRDISRFQSRELALTARLGQTEEQLWQVQADLDI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCH
DALTGIRNRRYFQRESIAAVTRACERSQALGLLILDVDQFKQYNDLHGHVAGDDCLRQIA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCCCCCCHHHHHHHH
GALARTLSGEQFCARLGGEEFAAVLPGATREETRDVARRMVAVVRDLGIAHNGTPVQPVV
HHHHHHCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TISVGAVWTVPEAPRLEPLLHRADSAMYRAKRAGRNRFMLDGDA
EEEECEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]