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The map label for this gene is norR2

Identifier: 116696261

GI number: 116696261

Start: 2634068

End: 2635633

Strand: Direct

Name: norR2

Synonym: H16_B2325

Alternate gene names: 116696261

Gene position: 2634068-2635633 (Clockwise)

Preceding gene: 116696258

Following gene: 116696262

Centisome position: 90.44

GC content: 71.39

Gene sequence:

>1566_bases
ATGCTACCGAGCGCGATGTATCCCGAGTTGCTGGCCGACCTTGTCACCGACCTGCCGCATGCGGTGCGCCTGCAGCGGCT
GGTCAGCATGCTGCGCACGCATTTCCGCTGTGGCGCGGTGGCGCTGCTGCGGCTGGAAGAAGACCACCTGCGCCCCGTTG
CGGTCGATGGCCTTGTGCGCGATGCGCTGGGCCGGCGCTTTGCGGTCGGCCTGCACCCGCGCCTGGCCGCGATCCTGGCG
CGGCGCGGGGTGACCTGCTTCCATCACGACAGCATGCTGCCCGACCCATACGACGGCCTGATCGACGAGCACGTTGGCGA
GCCGCTGCCGGTGCACGACTGCATGGGCACCAGCCTGGCCGTGGACGGCCAGCCCTGGGGCGCGCTGACGCTGGATGCGC
TGGCGATCGGCACCTTCGATGCCGCGGCCCAGGCCGAGCTGCAGCGGCTGACGGTGATCGTGGAAGCGGCCATCCGCACC
ACCCGGCTGGAAGGCGAGATCCGCGCGCTGCAGCTGGCACGCGGCACGCCCGAGGCCGACGAAGGCACGGCCCAGCATGG
CGACATCGGCGGCGAGATCATCGGCCAGAGCGAGGCCATCGCCAACCTGCTGCATGAGCTGGAGGTGGTGGCCGATACCG
ACCTGCCGGTACTGCTGCTGGGCGAGACCGGGGTGGGCAAGGAGCTGTTCGCGCACCGGCTGCACCGCCAGTCGCGCCGG
CGCGCGCAGCCGCTGGTGCATGTCAACTGCGCGGCGCTGCCGGAGTCGCTGGCTGAAAGCGAGCTGTTCGGCCATGCGCG
CGGCGCGTTCTCGGGCGCGACCGGCGAGCGCCCGGGACGCTTCGAGGCCGCCGACGGCGGCACCCTCTTCCTCGATGAAG
TCGGCGAACTGCCGCTGGCGATCCAGGCCAAGCTGCTGCGCACGCTGCAGAACGGCGAGATCCAGCGGCTGGGCTCGGAC
CGCCCGCGCCGCGTCAACGTGCGCGTGATTGCCGCGACCAACCGCAACCTGCGCGAGCATGTGCGCGACGGCTCGTTCCG
CGCCGACCTGTACCACCGCCTGTCGGTCTACCCGATCCCGATCCCGCCGCTGCGCGAGCGCGGCAACGACGTGCTGCTGC
TGGCCGGGCGCTTCCTGGAGCTGAACCGCGCGCGCCTGGGGCTGCGCAGCCTGCGGCTGTCAGGCGGTGCGCAGGATGCG
CTGCGCAGCTACCGCTGGCCCGGCAACGTGCGCGAGCTGGAACACGTGATCAGCCGCGCGGCGCTGCGTGCCGTCAGCCG
TGGCGCGGGCCGCAATGACATCGTGACGCTGGAGCCTGAACTGCTCGACCTCGACGGACTGGAAGTGCCCGCGGCACACC
ATGCCGGCGCCGGCATGGCCAGCGCGTTCGCCGCCCCGGCGCTTGCTGCAGGCATCACCCTGCGCGACGCGGTCGAGCAA
ACCCAGCGCGCCTGCATCGAACAGGCATTGAAGGACCAGGGTGGCAATTGGGCGCAGGCAGCGCGCCAGCTGGGTATCGA
TGCCAGCAACCTGCACAAGCTGGCCAGGCGGCTGGGGTGCAAGTGA

Upstream 100 bases:

>100_bases
GCCTGAAAAAAACCTATCCAGATCAATGGGTTGAAACACTGACGGTAATTAATACCCTATACTTCTCGCGGTACTTATCA
CCCTTACGGTATTTTTAACC

Downstream 100 bases:

>100_bases
CTGACACACTCGGGTGCCAGGATGCCGACATGGCGATGCGCGCCATTACCGCATAAGCTAGTCCGGGTGTGCCGCCCACA
TGTCGGCATCGCCGTGTGCA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLPSAMYPELLADLVTDLPHAVRLQRLVSMLRTHFRCGAVALLRLEEDHLRPVAVDGLVRDALGRRFAVGLHPRLAAILA
RRGVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLAVDGQPWGALTLDALAIGTFDAAAQAELQRLTVIVEAAIRT
TRLEGEIRALQLARGTPEADEGTAQHGDIGGEIIGQSEAIANLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRQSRR
RAQPLVHVNCAALPESLAESELFGHARGAFSGATGERPGRFEAADGGTLFLDEVGELPLAIQAKLLRTLQNGEIQRLGSD
RPRRVNVRVIAATNRNLREHVRDGSFRADLYHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGLRSLRLSGGAQDA
LRSYRWPGNVRELEHVISRAALRAVSRGAGRNDIVTLEPELLDLDGLEVPAAHHAGAGMASAFAAPALAAGITLRDAVEQ
TQRACIEQALKDQGGNWAQAARQLGIDASNLHKLARRLGCK

Sequences:

>Translated_521_residues
MLPSAMYPELLADLVTDLPHAVRLQRLVSMLRTHFRCGAVALLRLEEDHLRPVAVDGLVRDALGRRFAVGLHPRLAAILA
RRGVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLAVDGQPWGALTLDALAIGTFDAAAQAELQRLTVIVEAAIRT
TRLEGEIRALQLARGTPEADEGTAQHGDIGGEIIGQSEAIANLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRQSRR
RAQPLVHVNCAALPESLAESELFGHARGAFSGATGERPGRFEAADGGTLFLDEVGELPLAIQAKLLRTLQNGEIQRLGSD
RPRRVNVRVIAATNRNLREHVRDGSFRADLYHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGLRSLRLSGGAQDA
LRSYRWPGNVRELEHVISRAALRAVSRGAGRNDIVTLEPELLDLDGLEVPAAHHAGAGMASAFAAPALAAGITLRDAVEQ
TQRACIEQALKDQGGNWAQAARQLGIDASNLHKLARRLGCK
>Mature_521_residues
MLPSAMYPELLADLVTDLPHAVRLQRLVSMLRTHFRCGAVALLRLEEDHLRPVAVDGLVRDALGRRFAVGLHPRLAAILA
RRGVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLAVDGQPWGALTLDALAIGTFDAAAQAELQRLTVIVEAAIRT
TRLEGEIRALQLARGTPEADEGTAQHGDIGGEIIGQSEAIANLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRQSRR
RAQPLVHVNCAALPESLAESELFGHARGAFSGATGERPGRFEAADGGTLFLDEVGELPLAIQAKLLRTLQNGEIQRLGSD
RPRRVNVRVIAATNRNLREHVRDGSFRADLYHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGLRSLRLSGGAQDA
LRSYRWPGNVRELEHVISRAALRAVSRGAGRNDIVTLEPELLDLDGLEVPAAHHAGAGMASAFAAPALAAGITLRDAVEQ
TQRACIEQALKDQGGNWAQAARQLGIDASNLHKLARRLGCK

Specific function: Required for the nitric oxide (NO) induced expression of NO reductase. Not required for expression of 2 other pathway members, nitrate reductase (nirS) and nitrous oxide reductase (nosZ)

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI87082152, Length=517, Percent_Identity=47.9690522243714, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87082117, Length=250, Percent_Identity=53.6, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1789087, Length=254, Percent_Identity=52.3622047244094, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788550, Length=377, Percent_Identity=37.9310344827586, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1790437, Length=329, Percent_Identity=43.4650455927052, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1790299, Length=397, Percent_Identity=37.0277078085642, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081872, Length=331, Percent_Identity=38.0664652567976, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1789233, Length=337, Percent_Identity=37.0919881305638, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788905, Length=325, Percent_Identity=38.7692307692308, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1786524, Length=297, Percent_Identity=40.0673400673401, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1787583, Length=237, Percent_Identity=40.084388185654, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=37.6, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081858, Length=222, Percent_Identity=36.036036036036, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NORR2_CUPNH (Q9K4U8)

Other databases:

- EMBL:   AJ278372
- EMBL:   AM260480
- RefSeq:   YP_841837.1
- ProteinModelPortal:   Q9K4U8
- SMR:   Q9K4U8
- STRING:   Q9K4U8
- GeneID:   4456948
- GenomeReviews:   AM260480_GR
- KEGG:   reh:H16_B2325
- eggNOG:   COG3604
- HOGENOM:   HBG740884
- OMA:   TRREVTC
- PhylomeDB:   Q9K4U8
- ProtClustDB:   PRK05022
- BioCyc:   REUT381666:H16_B2325-MONOMER
- GO:   GO:0005622
- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- PRINTS:   PR01590
- SMART:   SM00382
- SMART:   SM00065

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 56494; Mature: 56494

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSAMYPELLADLVTDLPHAVRLQRLVSMLRTHFRCGAVALLRLEEDHLRPVAVDGLVR
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCHHEEEEECHHCCCCHHHHHHHH
DALGRRFAVGLHPRLAAILARRGVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLA
HHHCCEEEECCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEE
VDGQPWGALTLDALAIGTFDAAAQAELQRLTVIVEAAIRTTRLEGEIRALQLARGTPEAD
ECCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
EGTAQHGDIGGEIIGQSEAIANLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRQSRR
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
RAQPLVHVNCAALPESLAESELFGHARGAFSGATGERPGRFEAADGGTLFLDEVGELPLA
HCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEHHHHCCCCHH
IQAKLLRTLQNGEIQRLGSDRPRRVNVRVIAATNRNLREHVRDGSFRADLYHRLSVYPIP
HHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHCEEECCC
IPPLRERGNDVLLLAGRFLELNRARLGLRSLRLSGGAQDALRSYRWPGNVRELEHVISRA
CCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
ALRAVSRGAGRNDIVTLEPELLDLDGLEVPAAHHAGAGMASAFAAPALAAGITLRDAVEQ
HHHHHHCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
TQRACIEQALKDQGGNWAQAARQLGIDASNLHKLARRLGCK
HHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPSAMYPELLADLVTDLPHAVRLQRLVSMLRTHFRCGAVALLRLEEDHLRPVAVDGLVR
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCHHEEEEECHHCCCCHHHHHHHH
DALGRRFAVGLHPRLAAILARRGVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLA
HHHCCEEEECCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEE
VDGQPWGALTLDALAIGTFDAAAQAELQRLTVIVEAAIRTTRLEGEIRALQLARGTPEAD
ECCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
EGTAQHGDIGGEIIGQSEAIANLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRQSRR
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
RAQPLVHVNCAALPESLAESELFGHARGAFSGATGERPGRFEAADGGTLFLDEVGELPLA
HCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEHHHHCCCCHH
IQAKLLRTLQNGEIQRLGSDRPRRVNVRVIAATNRNLREHVRDGSFRADLYHRLSVYPIP
HHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHCEEECCC
IPPLRERGNDVLLLAGRFLELNRARLGLRSLRLSGGAQDALRSYRWPGNVRELEHVISRA
CCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
ALRAVSRGAGRNDIVTLEPELLDLDGLEVPAAHHAGAGMASAFAAPALAAGITLRDAVEQ
HHHHHHCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
TQRACIEQALKDQGGNWAQAARQLGIDASNLHKLARRLGCK
HHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11069685