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The map label for this gene is tar2 [H]

Identifier: 116696058

GI number: 116696058

Start: 2398620

End: 2399777

Strand: Direct

Name: tar2 [H]

Synonym: H16_B2122

Alternate gene names: 116696058

Gene position: 2398620-2399777 (Clockwise)

Preceding gene: 116696052

Following gene: 116696065

Centisome position: 82.36

GC content: 68.39

Gene sequence:

>1158_bases
ATGCAAAACCTGGGGATTCGCATACGCCTGGGCGCGGCGTTTGGCGCCATGTGGTCGCTGATGGCGATCGGGATCGCGGT
GGCCTTGCCGCGGATGCAGGAGGCGGCCGATGCGCGGCGCCTGCTGATCGCGTTGGGCGTGGGTGGGCTATGCCTGGCGG
TGGGCGCGGTCTGGGCGCTGGCGCGCAGCATCGAGGCGCCGTTGTCAGAAGCCGTCTACATAGCCGAGACCGTGGCGGCG
GGCGACCTCAGCCAGGAGTTCGACACCGAGCGCGGCGGCGAGTTTGGGCGGCTGCTGGGCGGCCTGGGAGAGATGGAAGA
CATGCTCACCGACCTGGTGACACGCATCCGCGCTTCCACCGATTCGATCACCGCCGCTTCGCACCAGATTGCCGCGGGCA
ATACCGACCTGTCGCAGCGCACGGAAGAGCAGGCGGCGGCGCTGGAAGAGACCGCGTCAAGCATGGGCGAGCTGACCTCG
ATGGTGCAGCAGAACACCGAACGCGCGCGCGCCGCCAACGGGCTGGCGGCAACCGCATCGGGAATCGCCGCGCGCGGTGG
CGAAGTGGTGGGCAACGTGGTGCAGACCATGTCGGCGATCAGCGCCAGCTCGCGCAAGGTCACGGACATCATCGAAGTGA
TCGAAGGCATTGCCTTCCAGACCAATATCCTGGCGCTGAACGCGGCGGTGGAAGCCGCGCGCGCGGGTGAGCAGGGGCGC
GGCTTTGCCGTGGTGGCCGGCGAGGTGCGAACGCTGGCGCAACGCAGTGCGTCGGCGGCGCGGGAGATCAAGCAACTGAT
CGACGATTCGGTGCAGCAGGTGGACAGCGGCTCGGCACTGGTGGGCCAGGCCGGCGAGACCATGCAGGAGATCGTTCAGG
CAGTGGCCAGCGTGACCGGGCTGCTGGGCGAGATCACTGCGGCCTCTGAACAGCAAAGTGCCGGGATTGCGCAGGTCAAC
GAGGCGGTGGCGCAGATGGACACCGTGACGCAGCAGAATGCGGCGCTGGTGGAGCAGGCGGCCAGTGCCTCGCACGAACT
GGCGGGCCAGGCCACTGAGCTGCAGCGCGTGGTGGGCGAGTTCAGGCTGGATGCGGAACCGGCGTCAGCACAGGCGCCGG
GGCATGGCGCATTCAGGCAGGTTGCTGCGTTCGGCTGA

Upstream 100 bases:

>100_bases
GTTCCCGCCGTTAAGCAAGAGTTGGCCAGCGAAGACATTGGCAAGACAGGCAGCCGGCACGCCGGCGCCTGCACTTCTGG
GGTGGAAACGGGGGAGAGAC

Downstream 100 bases:

>100_bases
TGTGGGCAGCGCGGATTGCTGACTGATTGCGCGCCCCCTCTCCCGCAAGCGGGAGAGGGGAGCGAACCAGCGGGAGGCAG
GACCCTTCAGCAATTCAAGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQNLGIRIRLGAAFGAMWSLMAIGIAVALPRMQEAADARRLLIALGVGGLCLAVGAVWALARSIEAPLSEAVYIAETVAA
GDLSQEFDTERGGEFGRLLGGLGEMEDMLTDLVTRIRASTDSITAASHQIAAGNTDLSQRTEEQAAALEETASSMGELTS
MVQQNTERARAANGLAATASGIAARGGEVVGNVVQTMSAISASSRKVTDIIEVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRTLAQRSASAAREIKQLIDDSVQQVDSGSALVGQAGETMQEIVQAVASVTGLLGEITAASEQQSAGIAQVN
EAVAQMDTVTQQNAALVEQAASASHELAGQATELQRVVGEFRLDAEPASAQAPGHGAFRQVAAFG

Sequences:

>Translated_385_residues
MQNLGIRIRLGAAFGAMWSLMAIGIAVALPRMQEAADARRLLIALGVGGLCLAVGAVWALARSIEAPLSEAVYIAETVAA
GDLSQEFDTERGGEFGRLLGGLGEMEDMLTDLVTRIRASTDSITAASHQIAAGNTDLSQRTEEQAAALEETASSMGELTS
MVQQNTERARAANGLAATASGIAARGGEVVGNVVQTMSAISASSRKVTDIIEVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRTLAQRSASAAREIKQLIDDSVQQVDSGSALVGQAGETMQEIVQAVASVTGLLGEITAASEQQSAGIAQVN
EAVAQMDTVTQQNAALVEQAASASHELAGQATELQRVVGEFRLDAEPASAQAPGHGAFRQVAAFG
>Mature_385_residues
MQNLGIRIRLGAAFGAMWSLMAIGIAVALPRMQEAADARRLLIALGVGGLCLAVGAVWALARSIEAPLSEAVYIAETVAA
GDLSQEFDTERGGEFGRLLGGLGEMEDMLTDLVTRIRASTDSITAASHQIAAGNTDLSQRTEEQAAALEETASSMGELTS
MVQQNTERARAANGLAATASGIAARGGEVVGNVVQTMSAISASSRKVTDIIEVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRTLAQRSASAAREIKQLIDDSVQQVDSGSALVGQAGETMQEIVQAVASVTGLLGEITAASEQQSAGIAQVN
EAVAQMDTVTQQNAALVEQAASASHELAGQATELQRVVGEFRLDAEPASAQAPGHGAFRQVAAFG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=328, Percent_Identity=54.2682926829268, Blast_Score=303, Evalue=9e-84,
Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=56.9230769230769, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=50.8928571428571, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788194, Length=324, Percent_Identity=48.4567901234568, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1789453, Length=301, Percent_Identity=39.8671096345515, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 39555; Mature: 39555

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLGIRIRLGAAFGAMWSLMAIGIAVALPRMQEAADARRLLIALGVGGLCLAVGAVWAL
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ARSIEAPLSEAVYIAETVAAGDLSQEFDTERGGEFGRLLGGLGEMEDMLTDLVTRIRAST
HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCC
DSITAASHQIAAGNTDLSQRTEEQAAALEETASSMGELTSMVQQNTERARAANGLAATAS
CCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GIAARGGEVVGNVVQTMSAISASSRKVTDIIEVIEGIAFQTNILALNAAVEAARAGEQGR
HHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFAVVAGEVRTLAQRSASAAREIKQLIDDSVQQVDSGSALVGQAGETMQEIVQAVASVTG
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHH
LLGEITAASEQQSAGIAQVNEAVAQMDTVTQQNAALVEQAASASHELAGQATELQRVVGE
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FRLDAEPASAQAPGHGAFRQVAAFG
HHCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQNLGIRIRLGAAFGAMWSLMAIGIAVALPRMQEAADARRLLIALGVGGLCLAVGAVWAL
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ARSIEAPLSEAVYIAETVAAGDLSQEFDTERGGEFGRLLGGLGEMEDMLTDLVTRIRAST
HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCC
DSITAASHQIAAGNTDLSQRTEEQAAALEETASSMGELTSMVQQNTERARAANGLAATAS
CCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GIAARGGEVVGNVVQTMSAISASSRKVTDIIEVIEGIAFQTNILALNAAVEAARAGEQGR
HHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFAVVAGEVRTLAQRSASAAREIKQLIDDSVQQVDSGSALVGQAGETMQEIVQAVASVTG
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHH
LLGEITAASEQQSAGIAQVNEAVAQMDTVTQQNAALVEQAASASHELAGQATELQRVVGE
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FRLDAEPASAQAPGHGAFRQVAAFG
HHCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]