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The map label for this gene is fepA [H]

Identifier: 116696031

GI number: 116696031

Start: 2361421

End: 2363391

Strand: Direct

Name: fepA [H]

Synonym: H16_B2095

Alternate gene names: 116696031

Gene position: 2361421-2363391 (Clockwise)

Preceding gene: 116696020

Following gene: 116696036

Centisome position: 81.08

GC content: 66.72

Gene sequence:

>1971_bases
ATGCGGATGCTGGCGGCGGCATGCGCCGCCTCCGGCATGACGGGAGCCTGGGCACAGGCGCAGGCGCTGAAGACGGAAGC
CACCCTCGCCACCGTGGTGGTGACGGCGGCCGGCAGTGAGCAGGACATCCGCGACGCGCCCGCGTCGATCAGCGTGGTCA
CGCGCAAAGACCTGGAGAACAAGGCCTATCGCGACATCAACGATGCGCTGGTGGAAGTGCCAGGCGTAATCGTCAGCGGC
GGCGGCGACCGGACCGACATCAGCCTGCGCGGCATGGGCGCCAAGTACACCCAGATCCTGATCGACGGCAAGCGCCAGAA
CTCGCGTGAGACCCGCACCAACTCCGACTCGTCCGGCGTGGAAAGCAGCTGGACGCCGCCGCTGTCCGCGATCGAGCGCA
TCGAGGTGGTGCGCGGGCCGATGTCGTCGCTGTACGGCTCCGACGCCATGGGCGGTGTGATCAACATCATCACGCGCAAG
GTGCCCAGGACGTGGACGGGCGAGTTGCGCGGCGACGCCACGCTGCAGGAGAACAGCGACTCCGGCAATCTCTACCAGGG
CAACTTCTACCTGGCCGGGCCGCTCAAGAGCGAGCTGCTGGGCCTGCAGCTGTACGGCCAGAGCACGCACCGCATCGAAG
ACGATATCGACTACGGCTTCCGCGGCCGCCGCGCCGAGAGCCTGACCGCCAAGCTGGCGCTGACGCCCACGCGCAACCAC
GACATCGTGTTCGAGGCCACCGGCATGCGCCAGCTGCGCAGCGAGACCGTGGGCAAGACCGTGCCGCCGCTGCCGCCCGG
CACCGCCTGCCCGCGCTCCGGCTGCCCCACCTCCTCCGAGACCGACTACCGCAGCGAGAAGTACGCGCTGTCGCATACCG
GCCGCTGGGGCTTCGGCGTCTCCGACAGCTATATCCAGCAGGAGGAGTTCGACAACCGCAGCCGCCGGATGAAGATCAAG
AACCTGGACCTGCGCACCAGCTGGGCCATGCCACTGGGCAACCATATGCTGTCGGTTGGCGGCGAATACCTGAACCAGCG
CCTGAACGACCAGACCGGCAACCAGATCGCCGGCGGCCCGAACCAGGTCGAGCGCTACCAGTGGGCGCTGTTTGCCGAGG
ACGAGTGGCGCCTGGCGCAGAGCTTTGCCCTGACCGGCGGCGTGCGCATGGATCACGACCAGAACTTCGGCCAGCACTAC
AGCCCGCGCTTGTACGGCGTGTGGCATGCGGCCGAGCGCTGGACGGTCAAGGGCGGGGTGTCGACCGGCTTCCGTGCGCC
GGACCTGCGCCAGACCGTGGCCGGCTGGGGCCAGACCAGCCGCGGCGGCAATATGTACGGCAACCCCGACCTGAAGCCCG
AGACGATGTTGTCGCAGGAACTGGGCCTGCTCTATGACAAGGGCAACGGCCTGCAGGCGGGCGTGACGCTGTTCAACAAC
GACTTCAAGGACAAGATCACGCGCGTCGCCTGCCCGGCCACGCAGTGCACCGACGCACCTAACCGGTTCGGCGCCAACCC
GACCACCTACATGAACGTGGACCGCGCCTACTCGCGCGGGGTGGAAGCCAGCCTGCGCTGGCCGATCGCGCAAGCGTGGT
CGCTGACCGGCAGCTATACCTATACCAAGTCGGAACAGAAGAGCGGCCAGTACCAGGGCCAGCCGCTGAACCAGTTGCCG
ATGCACCTGCTGGTGGCCACGCTGAACTGGCGGCCGAGCGAGAAGATCAACGCCTGGGCGCGCGTCAACTACCGCGGCAA
GGAAAGCCAGCCGATCACGGGGCCGTCATCCAGCACCGTGGTGGCGCCGTCGTACACCTTTGTCGACCTGGGGGCGACCT
ACACGGTTACCAGGAACGTGTCGGTGTTTGCCGGGATCTACAACCTCTTCGACAAGCAGGTGAACTACACCGACTATGGG
CATGTCGAGGATGGGCGCCGGTACTGGATGAGTGTGTCCGTGAAATTTTGA

Upstream 100 bases:

>100_bases
AGGGAAAATGATGAAGTTCAGGCAGGTCGCCGGGATCGGGGCGGCAACAAGAGCGGCGGCAGGGTTGCCAGCACCGGCGG
GCGTACAACGGGGTCAATGG

Downstream 100 bases:

>100_bases
AGGTGGCTGTTCTTGTTGTTGCCATGCGATTCGGCTGTGGCTCTTGGCAGGCGTGGGCTGTTTCGCCGGCGCAGCCGGCG
AAACAGCCCAGTCAAGAGCG

Product: enterobactin receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MRMLAAACAASGMTGAWAQAQALKTEATLATVVVTAAGSEQDIRDAPASISVVTRKDLENKAYRDINDALVEVPGVIVSG
GGDRTDISLRGMGAKYTQILIDGKRQNSRETRTNSDSSGVESSWTPPLSAIERIEVVRGPMSSLYGSDAMGGVINIITRK
VPRTWTGELRGDATLQENSDSGNLYQGNFYLAGPLKSELLGLQLYGQSTHRIEDDIDYGFRGRRAESLTAKLALTPTRNH
DIVFEATGMRQLRSETVGKTVPPLPPGTACPRSGCPTSSETDYRSEKYALSHTGRWGFGVSDSYIQQEEFDNRSRRMKIK
NLDLRTSWAMPLGNHMLSVGGEYLNQRLNDQTGNQIAGGPNQVERYQWALFAEDEWRLAQSFALTGGVRMDHDQNFGQHY
SPRLYGVWHAAERWTVKGGVSTGFRAPDLRQTVAGWGQTSRGGNMYGNPDLKPETMLSQELGLLYDKGNGLQAGVTLFNN
DFKDKITRVACPATQCTDAPNRFGANPTTYMNVDRAYSRGVEASLRWPIAQAWSLTGSYTYTKSEQKSGQYQGQPLNQLP
MHLLVATLNWRPSEKINAWARVNYRGKESQPITGPSSSTVVAPSYTFVDLGATYTVTRNVSVFAGIYNLFDKQVNYTDYG
HVEDGRRYWMSVSVKF

Sequences:

>Translated_656_residues
MRMLAAACAASGMTGAWAQAQALKTEATLATVVVTAAGSEQDIRDAPASISVVTRKDLENKAYRDINDALVEVPGVIVSG
GGDRTDISLRGMGAKYTQILIDGKRQNSRETRTNSDSSGVESSWTPPLSAIERIEVVRGPMSSLYGSDAMGGVINIITRK
VPRTWTGELRGDATLQENSDSGNLYQGNFYLAGPLKSELLGLQLYGQSTHRIEDDIDYGFRGRRAESLTAKLALTPTRNH
DIVFEATGMRQLRSETVGKTVPPLPPGTACPRSGCPTSSETDYRSEKYALSHTGRWGFGVSDSYIQQEEFDNRSRRMKIK
NLDLRTSWAMPLGNHMLSVGGEYLNQRLNDQTGNQIAGGPNQVERYQWALFAEDEWRLAQSFALTGGVRMDHDQNFGQHY
SPRLYGVWHAAERWTVKGGVSTGFRAPDLRQTVAGWGQTSRGGNMYGNPDLKPETMLSQELGLLYDKGNGLQAGVTLFNN
DFKDKITRVACPATQCTDAPNRFGANPTTYMNVDRAYSRGVEASLRWPIAQAWSLTGSYTYTKSEQKSGQYQGQPLNQLP
MHLLVATLNWRPSEKINAWARVNYRGKESQPITGPSSSTVVAPSYTFVDLGATYTVTRNVSVFAGIYNLFDKQVNYTDYG
HVEDGRRYWMSVSVKF
>Mature_656_residues
MRMLAAACAASGMTGAWAQAQALKTEATLATVVVTAAGSEQDIRDAPASISVVTRKDLENKAYRDINDALVEVPGVIVSG
GGDRTDISLRGMGAKYTQILIDGKRQNSRETRTNSDSSGVESSWTPPLSAIERIEVVRGPMSSLYGSDAMGGVINIITRK
VPRTWTGELRGDATLQENSDSGNLYQGNFYLAGPLKSELLGLQLYGQSTHRIEDDIDYGFRGRRAESLTAKLALTPTRNH
DIVFEATGMRQLRSETVGKTVPPLPPGTACPRSGCPTSSETDYRSEKYALSHTGRWGFGVSDSYIQQEEFDNRSRRMKIK
NLDLRTSWAMPLGNHMLSVGGEYLNQRLNDQTGNQIAGGPNQVERYQWALFAEDEWRLAQSFALTGGVRMDHDQNFGQHY
SPRLYGVWHAAERWTVKGGVSTGFRAPDLRQTVAGWGQTSRGGNMYGNPDLKPETMLSQELGLLYDKGNGLQAGVTLFNN
DFKDKITRVACPATQCTDAPNRFGANPTTYMNVDRAYSRGVEASLRWPIAQAWSLTGSYTYTKSEQKSGQYQGQPLNQLP
MHLLVATLNWRPSEKINAWARVNYRGKESQPITGPSSSTVVAPSYTFVDLGATYTVTRNVSVFAGIYNLFDKQVNYTDYG
HVEDGRRYWMSVSVKF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=691, Percent_Identity=37.0477568740955, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1786798, Length=730, Percent_Identity=30.6849315068493, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1790405, Length=160, Percent_Identity=36.875, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72395; Mature: 72395

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLAAACAASGMTGAWAQAQALKTEATLATVVVTAAGSEQDIRDAPASISVVTRKDLEN
CCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCHHHCCCCEEEEEEHHHHHH
KAYRDINDALVEVPGVIVSGGGDRTDISLRGMGAKYTQILIDGKRQNSRETRTNSDSSGV
HHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCC
ESSWTPPLSAIERIEVVRGPMSSLYGSDAMGGVINIITRKVPRTWTGELRGDATLQENSD
CCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
SGNLYQGNFYLAGPLKSELLGLQLYGQSTHRIEDDIDYGFRGRRAESLTAKLALTPTRNH
CCCEEECCEEEECCHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
DIVFEATGMRQLRSETVGKTVPPLPPGTACPRSGCPTSSETDYRSEKYALSHTGRWGFGV
CEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
SDSYIQQEEFDNRSRRMKIKNLDLRTSWAMPLGNHMLSVGGEYLNQRLNDQTGNQIAGGP
CHHHHHHHHHCCHHHEEEEECCCEEEEECCCCCCHHHHHCHHHHHHHHCCCCCCCCCCCC
NQVERYQWALFAEDEWRLAQSFALTGGVRMDHDQNFGQHYSPRLYGVWHAAERWTVKGGV
CHHHHEEEEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEECCC
STGFRAPDLRQTVAGWGQTSRGGNMYGNPDLKPETMLSQELGLLYDKGNGLQAGVTLFNN
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCEECEEEECC
DFKDKITRVACPATQCTDAPNRFGANPTTYMNVDRAYSRGVEASLRWPIAQAWSLTGSYT
CHHHHHHHHCCCCHHCCCCCHHCCCCCCEEEECHHHHHCCCCCEECCCHHHHHCCCCCEE
YTKSEQKSGQYQGQPLNQLPMHLLVATLNWRPSEKINAWARVNYRGKESQPITGPSSSTV
ECCCHHCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
VAPSYTFVDLGATYTVTRNVSVFAGIYNLFDKQVNYTDYGHVEDGRRYWMSVSVKF
EECCEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MRMLAAACAASGMTGAWAQAQALKTEATLATVVVTAAGSEQDIRDAPASISVVTRKDLEN
CCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCHHHCCCCEEEEEEHHHHHH
KAYRDINDALVEVPGVIVSGGGDRTDISLRGMGAKYTQILIDGKRQNSRETRTNSDSSGV
HHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCC
ESSWTPPLSAIERIEVVRGPMSSLYGSDAMGGVINIITRKVPRTWTGELRGDATLQENSD
CCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
SGNLYQGNFYLAGPLKSELLGLQLYGQSTHRIEDDIDYGFRGRRAESLTAKLALTPTRNH
CCCEEECCEEEECCHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
DIVFEATGMRQLRSETVGKTVPPLPPGTACPRSGCPTSSETDYRSEKYALSHTGRWGFGV
CEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
SDSYIQQEEFDNRSRRMKIKNLDLRTSWAMPLGNHMLSVGGEYLNQRLNDQTGNQIAGGP
CHHHHHHHHHCCHHHEEEEECCCEEEEECCCCCCHHHHHCHHHHHHHHCCCCCCCCCCCC
NQVERYQWALFAEDEWRLAQSFALTGGVRMDHDQNFGQHYSPRLYGVWHAAERWTVKGGV
CHHHHEEEEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEECCC
STGFRAPDLRQTVAGWGQTSRGGNMYGNPDLKPETMLSQELGLLYDKGNGLQAGVTLFNN
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCEECEEEECC
DFKDKITRVACPATQCTDAPNRFGANPTTYMNVDRAYSRGVEASLRWPIAQAWSLTGSYT
CHHHHHHHHCCCCHHCCCCCHHCCCCCCEEEECHHHHHCCCCCEECCCHHHHHCCCCCEE
YTKSEQKSGQYQGQPLNQLPMHLLVATLNWRPSEKINAWARVNYRGKESQPITGPSSSTV
ECCCHHCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
VAPSYTFVDLGATYTVTRNVSVFAGIYNLFDKQVNYTDYGHVEDGRRYWMSVSVKF
EECCEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]