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The map label for this gene is rcsB [H]

Identifier: 116696017

GI number: 116696017

Start: 2340818

End: 2341483

Strand: Direct

Name: rcsB [H]

Synonym: H16_B2081

Alternate gene names: 116696017

Gene position: 2340818-2341483 (Clockwise)

Preceding gene: 116696016

Following gene: 116696020

Centisome position: 80.37

GC content: 65.17

Gene sequence:

>666_bases
ATGACATTGAGGATCCTGCTTGCCGACGACCACCCCCTGGTCAGCGCAGCCGTCGCGGACCGCCTGCATACCCAGACCGG
GTGGGAGGTGTGCGGCTGCGTGACCAGCGCGACGGCCTTGCTGAACAGCGTGGAAAGCCTGCGTCCCGATGTCGTGATCA
CCGACTACCACATGCCCGCGCACGGCGAAGGCAACAGCGACGGCCTGCGCCTGCTTGCCAGCCTGCGGCGGCGGCATCCG
TCGCTGGCCGTGATCGTGCTGACCATGATCACCAATCCGCTGGTGCTGCGCTCCATCCTGGACACCCAGGTGCACGGCCT
GCTGCTCAAGGACTCGCCCCTGTCAGAACTGGTGACTGTGGTTTGCCGTATCCAGCGGGGCTTCCACTACATCGGCAAAT
CCGCGCTTGAAGTACTGTCGCAGGCCGATCCCGGCAACCCGGCCACACCCGGCCAGGCCGGCGCGGAGCGCCTGTCCCGG
CGTGAAATGGAAGTATTGCGGCTGTACCTGACCGGACGGTCCGTGAGTGAGATCGCCGTCCTGCTCTGCCGCAGCGTCAA
GACCATCAGCCGGCAGAAGAACTGCGCCATGCAGAAGCTCGGCGTCACCAACGACCGGGAACTGTTTGAATTCGCGGCGC
TGAACGGCATGCTGCTGACTGCCTGA

Upstream 100 bases:

>100_bases
GTCGTATTGTTTGGCGTCGTTTTTGCGCCGCACGTCTCGCTGACGTGCGGCGTTTTCTTGATGCCGGCGCTGCCACGAAC
AAGAATCGAGGAGCAACCAG

Downstream 100 bases:

>100_bases
GCGCCAGCGGCACGGGCGCGGCCGTATCAGGCGGCGTCGGCTGCCTGTGCCGCATGGGCCTGCGCGTATGCAATGCCGGC
CTCCAGCCGCGCCAGTCCGC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTLRILLADDHPLVSAAVADRLHTQTGWEVCGCVTSATALLNSVESLRPDVVITDYHMPAHGEGNSDGLRLLASLRRRHP
SLAVIVLTMITNPLVLRSILDTQVHGLLLKDSPLSELVTVVCRIQRGFHYIGKSALEVLSQADPGNPATPGQAGAERLSR
REMEVLRLYLTGRSVSEIAVLLCRSVKTISRQKNCAMQKLGVTNDRELFEFAALNGMLLTA

Sequences:

>Translated_221_residues
MTLRILLADDHPLVSAAVADRLHTQTGWEVCGCVTSATALLNSVESLRPDVVITDYHMPAHGEGNSDGLRLLASLRRRHP
SLAVIVLTMITNPLVLRSILDTQVHGLLLKDSPLSELVTVVCRIQRGFHYIGKSALEVLSQADPGNPATPGQAGAERLSR
REMEVLRLYLTGRSVSEIAVLLCRSVKTISRQKNCAMQKLGVTNDRELFEFAALNGMLLTA
>Mature_220_residues
TLRILLADDHPLVSAAVADRLHTQTGWEVCGCVTSATALLNSVESLRPDVVITDYHMPAHGEGNSDGLRLLASLRRRHPS
LAVIVLTMITNPLVLRSILDTQVHGLLLKDSPLSELVTVVCRIQRGFHYIGKSALEVLSQADPGNPATPGQAGAERLSRR
EMEVLRLYLTGRSVSEIAVLLCRSVKTISRQKNCAMQKLGVTNDRELFEFAALNGMLLTA

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=38.8625592417062, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=25.8215962441315, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788222, Length=218, Percent_Identity=27.9816513761468, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24099; Mature: 23968

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRILLADDHPLVSAAVADRLHTQTGWEVCGCVTSATALLNSVESLRPDVVITDYHMPA
CEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
HGEGNSDGLRLLASLRRRHPSLAVIVLTMITNPLVLRSILDTQVHGLLLKDSPLSELVTV
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEEECCCCHHHHHHH
VCRIQRGFHYIGKSALEVLSQADPGNPATPGQAGAERLSRREMEVLRLYLTGRSVSEIAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LLCRSVKTISRQKNCAMQKLGVTNDRELFEFAALNGMLLTA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEECC
>Mature Secondary Structure 
TLRILLADDHPLVSAAVADRLHTQTGWEVCGCVTSATALLNSVESLRPDVVITDYHMPA
EEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
HGEGNSDGLRLLASLRRRHPSLAVIVLTMITNPLVLRSILDTQVHGLLLKDSPLSELVTV
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEEECCCCHHHHHHH
VCRIQRGFHYIGKSALEVLSQADPGNPATPGQAGAERLSRREMEVLRLYLTGRSVSEIAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LLCRSVKTISRQKNCAMQKLGVTNDRELFEFAALNGMLLTA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]