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The map label for this gene is cheA2Y2 [H]

Identifier: 116695984

GI number: 116695984

Start: 2303712

End: 2305967

Strand: Direct

Name: cheA2Y2 [H]

Synonym: H16_B2048

Alternate gene names: 116695984

Gene position: 2303712-2305967 (Clockwise)

Preceding gene: 116695983

Following gene: 116695985

Centisome position: 79.1

GC content: 71.72

Gene sequence:

>2256_bases
ATGAATTCCGAGCAACTGCGCGACGCCTCGCTGCTGGAACTGTTCGCGCTCGAGGCCGATGCCCAGGCCGAAGTCCTCAA
TGCCGGCCTGCTGGCGCTGGAGCGCAACCCGGCAGCCGCCGAGCAGCTCGAAGCCTGCATGCGTGCCGCCCACTCGCTCA
AGGGCGCGGCCCGCATCGTCGGGCTCGATGGCGGCGTGCGCGTAGCACACGCCATGGAAGACTGCCTGGTCGCCGCACAG
GGCGGCATGCCGCTGACCGCCGCGCATATCGACGCGCTGCTGCAAGGCACCGACCTGCTGCTGCGCATCGGCCATCCGCC
CGGCGGCAATCCGGGCTGGGCCGAGCACGCGGGCCGCGCCGAGATCGATGCAGTGGTGCAGCGGCTGGGCACGGTCGATG
GCGGTGCCGCGGCGCCGGTCGTGCAGGCACAGCCAGCGCCGGCCCCGTTACCGGAACCAGCGCCCGCGATACCGGCGCCG
CCGGCACCGGCAGACGACACACAGGAGCGCATGCTGCGCGTGAATGCCGACGCGCTTGACCAGTTGCTGGCGCTGTCCGG
CGAGGCCATGGTCGAGTCGCACTGGCTGCGCCCCTTCGGCACCTCGCTGCAGAAGGCAAGGCGGCAACAGGCACGCGCAC
TGCGCGCCGTCGATGCGCTGCAGCAAGCCTTGCAGGACGGCAACGCGGGCGCGGCTGCGCACACCGCGCTGGCAGAACTG
CGCCAGCTGCTGGACGAAAGCCACGATCAGCTGGCCGCGCGGCTGGAAGAGTTCGAACAGTACGATCACCGCGCCACGCG
GCTGGCGCGCCGGCTCTATGACAGCGCGCTGGCCTCGCGCATGCGCCCGCTGGCGGACGCGCTGACCGGCTATGCGCGCA
TGGTGCGCGACCTCGGGCGCGCGCTCGGCAAGCCGGTGCACCTGGACCTGATCGGCGCCGGCACCCAGGTGGACCGCGAT
ATCCTGGAAGCACTGGACGCGCCGCTGGCGCACCTGCTGCGCAACGCGGTGGACCACGGCATCGAAGCGCCCGAGGTGCG
CGCGGCGCAGGGCAAGCCGGCGGAAGGCCGCGTCACGCTGCAGGCGCGCCACAACGCGGGCCGCCTGGTGATCGAAATCT
TCGACGACGGCGCCGGCGTCGACCTGGAAGCCCTGCGCGACGCCATCGTGCGGCGGCGGCTGGCGTCCGCAGAGACCGCG
GCACGGCTGTCGCAGGCAGAGCTGCTCGACTTCCTGCTGCTGCCGGGCTTCAGCATGCGCGACTCGGTCTCCGAGGTCTC
CGGCCGCGGCGTGGGCCTCGATGCCGTGCAGGAGATGGTGCGCCGCGTGCGTGGCAGCCTGCGCCTGACGCAGCAGCCGG
GCCAGGGCCTGCACTTCCGGATGGAGTTGCCACTGACGCTGTCGGTGGTGCGCGCTCTGCTGGTGGAGGTCGCGGGCGAA
GCCTATGCCTTCCCGCTGGGCCGCGTGCTGCGCGCGGCCTCGGTGGCGCGCAGCGAGATCGAGCAGACCGAAGGGCACCA
GCATTTCCGCCACGAAGGCCGCGCCATCGGGCTGGTCAGCGCGGCGCAGGTGCTGCAACGCCCCGAGGCTGACGCTGCCA
ATGCGCACGCGCAAGTGCCAGTGGTGGTCATCGGCGAGGCCGAGCGCATCTATGGCATTGCCGTCGACCGCATGCTGGGC
GAGCGCCTGCTGGTGGTGCAGCCGCTGCCGGCGGCACTGGGCAAGGTCCGCGACATCGCCGCCGGCAGCCTCACCGACGA
CGGCACGCCGGTGCTGATCTTCGATGTCGAGGACGTGATCCGCTCGGTCGAGAAGCTGGTCTCCGAGGGCCGCATCGAAG
GCGTGCGGCAGGCGGCCGTGGCCAGCGTCCAGGCGCGCGCGCGGCGCGTGCTGGTGGTGGACGACTCGCTCACCGTGCGC
GAGCTGCAGCGCAAGCTGCTGGCCGGGCGCGGCTATGACGTGGCGGTGGCGGTCGACGGCATGGACGGCTGGAATGTGCT
GCGCGCCGAGCCCTTCGACCTGGTCATCACCGATATCGACATGCCGCGCATGGACGGCATCGAGCTGGTGCGCCGGATCC
GGCAGGACGCCGCGCTGCGGCAGCTGCCGGTGATGGTGGTGTCGTACAAGGACCGCGAACAGGACCGCCAGCGCGGGCTC
GAGGCCGGCGCGGACTATTATCTGGCCAAGGGCAGTTTCCACGACGCCGCGTTGCTCGACGCGGTCCATGACCTGATCGG
CGAGGCACGCCCATGA

Upstream 100 bases:

>100_bases
CCTCGGCGCGCTACACGCAGGCGCTGTTCCTCGACCAGGGCCGCAGCGTCGGGCTGCTCGATGCCGCACTGGTACGCCAG
GCGCTGGCCAGGAGCCTGGC

Downstream 100 bases:

>100_bases
AGATCGGCATCGTCAATGACTCGGCGCTTGCGGTAGCCGCGCTGCGCCGCGCGCTTGCGCTGGATCCGTCGTTCGAGATC
GCCTGGGTCGCCGGCGACGG

Product: chemotaxis specific sensory transducer kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MNSEQLRDASLLELFALEADAQAEVLNAGLLALERNPAAAEQLEACMRAAHSLKGAARIVGLDGGVRVAHAMEDCLVAAQ
GGMPLTAAHIDALLQGTDLLLRIGHPPGGNPGWAEHAGRAEIDAVVQRLGTVDGGAAAPVVQAQPAPAPLPEPAPAIPAP
PAPADDTQERMLRVNADALDQLLALSGEAMVESHWLRPFGTSLQKARRQQARALRAVDALQQALQDGNAGAAAHTALAEL
RQLLDESHDQLAARLEEFEQYDHRATRLARRLYDSALASRMRPLADALTGYARMVRDLGRALGKPVHLDLIGAGTQVDRD
ILEALDAPLAHLLRNAVDHGIEAPEVRAAQGKPAEGRVTLQARHNAGRLVIEIFDDGAGVDLEALRDAIVRRRLASAETA
ARLSQAELLDFLLLPGFSMRDSVSEVSGRGVGLDAVQEMVRRVRGSLRLTQQPGQGLHFRMELPLTLSVVRALLVEVAGE
AYAFPLGRVLRAASVARSEIEQTEGHQHFRHEGRAIGLVSAAQVLQRPEADAANAHAQVPVVVIGEAERIYGIAVDRMLG
ERLLVVQPLPAALGKVRDIAAGSLTDDGTPVLIFDVEDVIRSVEKLVSEGRIEGVRQAAVASVQARARRVLVVDDSLTVR
ELQRKLLAGRGYDVAVAVDGMDGWNVLRAEPFDLVITDIDMPRMDGIELVRRIRQDAALRQLPVMVVSYKDREQDRQRGL
EAGADYYLAKGSFHDAALLDAVHDLIGEARP

Sequences:

>Translated_751_residues
MNSEQLRDASLLELFALEADAQAEVLNAGLLALERNPAAAEQLEACMRAAHSLKGAARIVGLDGGVRVAHAMEDCLVAAQ
GGMPLTAAHIDALLQGTDLLLRIGHPPGGNPGWAEHAGRAEIDAVVQRLGTVDGGAAAPVVQAQPAPAPLPEPAPAIPAP
PAPADDTQERMLRVNADALDQLLALSGEAMVESHWLRPFGTSLQKARRQQARALRAVDALQQALQDGNAGAAAHTALAEL
RQLLDESHDQLAARLEEFEQYDHRATRLARRLYDSALASRMRPLADALTGYARMVRDLGRALGKPVHLDLIGAGTQVDRD
ILEALDAPLAHLLRNAVDHGIEAPEVRAAQGKPAEGRVTLQARHNAGRLVIEIFDDGAGVDLEALRDAIVRRRLASAETA
ARLSQAELLDFLLLPGFSMRDSVSEVSGRGVGLDAVQEMVRRVRGSLRLTQQPGQGLHFRMELPLTLSVVRALLVEVAGE
AYAFPLGRVLRAASVARSEIEQTEGHQHFRHEGRAIGLVSAAQVLQRPEADAANAHAQVPVVVIGEAERIYGIAVDRMLG
ERLLVVQPLPAALGKVRDIAAGSLTDDGTPVLIFDVEDVIRSVEKLVSEGRIEGVRQAAVASVQARARRVLVVDDSLTVR
ELQRKLLAGRGYDVAVAVDGMDGWNVLRAEPFDLVITDIDMPRMDGIELVRRIRQDAALRQLPVMVVSYKDREQDRQRGL
EAGADYYLAKGSFHDAALLDAVHDLIGEARP
>Mature_751_residues
MNSEQLRDASLLELFALEADAQAEVLNAGLLALERNPAAAEQLEACMRAAHSLKGAARIVGLDGGVRVAHAMEDCLVAAQ
GGMPLTAAHIDALLQGTDLLLRIGHPPGGNPGWAEHAGRAEIDAVVQRLGTVDGGAAAPVVQAQPAPAPLPEPAPAIPAP
PAPADDTQERMLRVNADALDQLLALSGEAMVESHWLRPFGTSLQKARRQQARALRAVDALQQALQDGNAGAAAHTALAEL
RQLLDESHDQLAARLEEFEQYDHRATRLARRLYDSALASRMRPLADALTGYARMVRDLGRALGKPVHLDLIGAGTQVDRD
ILEALDAPLAHLLRNAVDHGIEAPEVRAAQGKPAEGRVTLQARHNAGRLVIEIFDDGAGVDLEALRDAIVRRRLASAETA
ARLSQAELLDFLLLPGFSMRDSVSEVSGRGVGLDAVQEMVRRVRGSLRLTQQPGQGLHFRMELPLTLSVVRALLVEVAGE
AYAFPLGRVLRAASVARSEIEQTEGHQHFRHEGRAIGLVSAAQVLQRPEADAANAHAQVPVVVIGEAERIYGIAVDRMLG
ERLLVVQPLPAALGKVRDIAAGSLTDDGTPVLIFDVEDVIRSVEKLVSEGRIEGVRQAAVASVQARARRVLVVDDSLTVR
ELQRKLLAGRGYDVAVAVDGMDGWNVLRAEPFDLVITDIDMPRMDGIELVRRIRQDAALRQLPVMVVSYKDREQDRQRGL
EAGADYYLAKGSFHDAALLDAVHDLIGEARP

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=385, Percent_Identity=32.2077922077922, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI145693157, Length=331, Percent_Identity=26.2839879154079, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=103, Percent_Identity=40.7766990291262, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=34.1666666666667, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=101, Percent_Identity=35.6435643564356, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786599, Length=104, Percent_Identity=34.6153846153846, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80750; Mature: 80750

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEQLRDASLLELFALEADAQAEVLNAGLLALERNPAAAEQLEACMRAAHSLKGAARIV
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCEEEE
GLDGGVRVAHAMEDCLVAAQGGMPLTAAHIDALLQGTDLLLRIGHPPGGNPGWAEHAGRA
ECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCH
EIDAVVQRLGTVDGGAAAPVVQAQPAPAPLPEPAPAIPAPPAPADDTQERMLRVNADALD
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHH
QLLALSGEAMVESHWLRPFGTSLQKARRQQARALRAVDALQQALQDGNAGAAAHTALAEL
HHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RQLLDESHDQLAARLEEFEQYDHRATRLARRLYDSALASRMRPLADALTGYARMVRDLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGKPVHLDLIGAGTQVDRDILEALDAPLAHLLRNAVDHGIEAPEVRAAQGKPAEGRVTL
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
QARHNAGRLVIEIFDDGAGVDLEALRDAIVRRRLASAETAARLSQAELLDFLLLPGFSMR
EEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DSVSEVSGRGVGLDAVQEMVRRVRGSLRLTQQPGQGLHFRMELPLTLSVVRALLVEVAGE
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCC
AYAFPLGRVLRAASVARSEIEQTEGHQHFRHEGRAIGLVSAAQVLQRPEADAANAHAQVP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCCCCC
VVVIGEAERIYGIAVDRMLGERLLVVQPLPAALGKVRDIAAGSLTDDGTPVLIFDVEDVI
EEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHH
RSVEKLVSEGRIEGVRQAAVASVQARARRVLVVDDSLTVRELQRKLLAGRGYDVAVAVDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEC
MDGWNVLRAEPFDLVITDIDMPRMDGIELVRRIRQDAALRQLPVMVVSYKDREQDRQRGL
CCCCCEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCH
EAGADYYLAKGSFHDAALLDAVHDLIGEARP
HCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSEQLRDASLLELFALEADAQAEVLNAGLLALERNPAAAEQLEACMRAAHSLKGAARIV
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCEEEE
GLDGGVRVAHAMEDCLVAAQGGMPLTAAHIDALLQGTDLLLRIGHPPGGNPGWAEHAGRA
ECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCH
EIDAVVQRLGTVDGGAAAPVVQAQPAPAPLPEPAPAIPAPPAPADDTQERMLRVNADALD
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHH
QLLALSGEAMVESHWLRPFGTSLQKARRQQARALRAVDALQQALQDGNAGAAAHTALAEL
HHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RQLLDESHDQLAARLEEFEQYDHRATRLARRLYDSALASRMRPLADALTGYARMVRDLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGKPVHLDLIGAGTQVDRDILEALDAPLAHLLRNAVDHGIEAPEVRAAQGKPAEGRVTL
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
QARHNAGRLVIEIFDDGAGVDLEALRDAIVRRRLASAETAARLSQAELLDFLLLPGFSMR
EEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DSVSEVSGRGVGLDAVQEMVRRVRGSLRLTQQPGQGLHFRMELPLTLSVVRALLVEVAGE
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCC
AYAFPLGRVLRAASVARSEIEQTEGHQHFRHEGRAIGLVSAAQVLQRPEADAANAHAQVP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCCCCC
VVVIGEAERIYGIAVDRMLGERLLVVQPLPAALGKVRDIAAGSLTDDGTPVLIFDVEDVI
EEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHH
RSVEKLVSEGRIEGVRQAAVASVQARARRVLVVDDSLTVRELQRKLLAGRGYDVAVAVDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEC
MDGWNVLRAEPFDLVITDIDMPRMDGIELVRRIRQDAALRQLPVMVVSYKDREQDRQRGL
CCCCCEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCH
EAGADYYLAKGSFHDAALLDAVHDLIGEARP
HCCCCEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]