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The map label for this gene is mcp [H]

Identifier: 116695980

GI number: 116695980

Start: 2299618

End: 2301273

Strand: Direct

Name: mcp [H]

Synonym: H16_B2044

Alternate gene names: 116695980

Gene position: 2299618-2301273 (Clockwise)

Preceding gene: 116695977

Following gene: 116695981

Centisome position: 78.96

GC content: 67.87

Gene sequence:

>1656_bases
ATGGCCGCTCCTGAACAAGAACATCACCGGGACCACACCGTGAACGAATGGACCATCCGCACGCGCATCCTGGCAAGCTT
TTCGCTGATCCTGCTTGTCATGGCGCTGATGGGCGTTGTCTCCTACACCCGCCTGAGCGCCATTGAGCGCGAAACCACGC
TGATGCTGAAGGACGCGCTGCCCGGACTGAACCACAGTACCGGCATCCGCGGCATCTGGGGCGAGCGCTACGTGCTGGCG
TGGCAGACCATCAATGCCGCCGACGAGGCCGAGCGGCGCAGCTTCCAGCAACAGGGCCAGGACGCCGCAAGCCGGCTCGA
CAAGGTCGAGCAGCAGTACGAGACCTCGATCACGCGCGACGAAGACCGCGCCGCCTTCAGGGCCTATCGGGACGTGCGCG
CGCAATACGAACAGGCAGCCCAGATCCTGACCCGGACGGGCGAGTGGAACGGCGCCGCCGCCTCAGCCGCGTTGCGCGGC
ACCGTGCATGACCGCTGGATCGAGGCGCGCAAGGCCGCCCAGCACCTGGTGGACGACAACAGCGCGGTCAATGCGCGGGC
GGCGCGCGGCATCGACGACGCCGTCAATGCCGCCAAGATCGGCATCGAAGCGGCACTGATCGTGGCCCTGGTGGTCGCCA
TCGTCTGCGGCTACCTGCTGCTGCGCGCGATCACAGTGCCGATGCAGTCGATCGTCAACCTGCTGTCCGGCATCCGCGGC
GGCGACCTGCGCCTGCGCATGGCGCTGCGCCGCAAGGACGAATTCCAGGAAGTGGAGGCAGGTTTCAACCAGATGACGGG
AGAGCTGACCTCGCTGGTGGGCCAGGCGCAGCGCACCGCGATCCAGGTCACCACCTCGGTCAACGAGATCGCCGCGACGG
CGCGCCAGCAGCAGGCCACCGCCACCGAGACCGCCGCCACCACGACCCAGATCGGCGCGACCTCGCGCGAGATCTCGGCC
ACCGCGCGCGACCTGGTGCGCACCATCCATGAAGTCTCCAGCGCCGCCGAGCAGGCGGCCGGGCTGGCCGGCACCGGCCA
GGTCGGGCTGTCGCGCATGGAAGGCACCATGCAGCATGTGATGGACGCCGCCGGCTCGGTCAATGCCAAGCTGGCCACGC
TCAACGAAAAGGCCAGCAATATCAACCAGGTCGTGACCACCATCGCCAAGGTGGCCGACCAGACCAACCTGCTGTCGCTG
AACGCCGCGATCGAGGCCGAGAAGGCCGGCGAATACGGCCGCGGCTTTGCCGTGGTGGCGACCGAGATCCGCCGCCTGGC
CGACCAGACCGCGGTGGCCACCTACGATATCGAGCAGATGGTGCGCGAGATCCAGTCGGCGGTGTCGGCGGGCGTGATGG
GCATGGACAAGTTCTCGGAGGAAGTGCGCCGCGGCATGTCCGAGGTCACGCAGGTCGGCGACCAGCTGTCGCAGATCATC
GCGCAGGTGCAGTCGCTGGCGCCGCGCGTGCTGATGGTCAATGAAGGCATGCAGGCCCAGGCCGGCGGCGCCGAGCAGAT
CAACCAGGCGCTGATGCAGCTGTCCGAGGCCGCGCAGCAGACCGTGGAGTCGCTGCGCCAGTCGAGCCAGGCGATCGACG
AACTGACGCTGGTGGCCAACGACCTGCGCAGCGGCGTCTCGCGCTTCAAGGTCTAG

Upstream 100 bases:

>100_bases
GTCCCGGCTTACAGTACCCTACCGCGCGTCGAGGCCGCCCGCCGCCGCCGCGCCGCCCCTTGCTACCCCGAGAGGAGCCC
CTGAGGCGGCTTTGCGGGGA

Downstream 100 bases:

>100_bases
GGCCTGCGCCCCGCCGCCATGAAACTTTTCCTGCTGTTCCGCCTCGGCGCTGACCACTATGCGCTCGATGCCGCCGAGGT
GGCCGAGGTGCTGCCGCTCA

Product: methyl-accepting chemotaxis transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MAAPEQEHHRDHTVNEWTIRTRILASFSLILLVMALMGVVSYTRLSAIERETTLMLKDALPGLNHSTGIRGIWGERYVLA
WQTINAADEAERRSFQQQGQDAASRLDKVEQQYETSITRDEDRAAFRAYRDVRAQYEQAAQILTRTGEWNGAAASAALRG
TVHDRWIEARKAAQHLVDDNSAVNARAARGIDDAVNAAKIGIEAALIVALVVAIVCGYLLLRAITVPMQSIVNLLSGIRG
GDLRLRMALRRKDEFQEVEAGFNQMTGELTSLVGQAQRTAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISA
TARDLVRTIHEVSSAAEQAAGLAGTGQVGLSRMEGTMQHVMDAAGSVNAKLATLNEKASNINQVVTTIAKVADQTNLLSL
NAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMSEVTQVGDQLSQII
AQVQSLAPRVLMVNEGMQAQAGGAEQINQALMQLSEAAQQTVESLRQSSQAIDELTLVANDLRSGVSRFKV

Sequences:

>Translated_551_residues
MAAPEQEHHRDHTVNEWTIRTRILASFSLILLVMALMGVVSYTRLSAIERETTLMLKDALPGLNHSTGIRGIWGERYVLA
WQTINAADEAERRSFQQQGQDAASRLDKVEQQYETSITRDEDRAAFRAYRDVRAQYEQAAQILTRTGEWNGAAASAALRG
TVHDRWIEARKAAQHLVDDNSAVNARAARGIDDAVNAAKIGIEAALIVALVVAIVCGYLLLRAITVPMQSIVNLLSGIRG
GDLRLRMALRRKDEFQEVEAGFNQMTGELTSLVGQAQRTAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISA
TARDLVRTIHEVSSAAEQAAGLAGTGQVGLSRMEGTMQHVMDAAGSVNAKLATLNEKASNINQVVTTIAKVADQTNLLSL
NAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMSEVTQVGDQLSQII
AQVQSLAPRVLMVNEGMQAQAGGAEQINQALMQLSEAAQQTVESLRQSSQAIDELTLVANDLRSGVSRFKV
>Mature_550_residues
AAPEQEHHRDHTVNEWTIRTRILASFSLILLVMALMGVVSYTRLSAIERETTLMLKDALPGLNHSTGIRGIWGERYVLAW
QTINAADEAERRSFQQQGQDAASRLDKVEQQYETSITRDEDRAAFRAYRDVRAQYEQAAQILTRTGEWNGAAASAALRGT
VHDRWIEARKAAQHLVDDNSAVNARAARGIDDAVNAAKIGIEAALIVALVVAIVCGYLLLRAITVPMQSIVNLLSGIRGG
DLRLRMALRRKDEFQEVEAGFNQMTGELTSLVGQAQRTAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISAT
ARDLVRTIHEVSSAAEQAAGLAGTGQVGLSRMEGTMQHVMDAAGSVNAKLATLNEKASNINQVVTTIAKVADQTNLLSLN
AAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIA
QVQSLAPRVLMVNEGMQAQAGGAEQINQALMQLSEAAQQTVESLRQSSQAIDELTLVANDLRSGVSRFKV

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI2367378, Length=281, Percent_Identity=29.8932384341637, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788194, Length=346, Percent_Identity=27.4566473988439, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788195, Length=266, Percent_Identity=28.9473684210526, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=336, Percent_Identity=24.702380952381, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007891
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF05227 CHASE3; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59599; Mature: 59468

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPEQEHHRDHTVNEWTIRTRILASFSLILLVMALMGVVSYTRLSAIERETTLMLKDAL
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLNHSTGIRGIWGERYVLAWQTINAADEAERRSFQQQGQDAASRLDKVEQQYETSITRD
CCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
EDRAAFRAYRDVRAQYEQAAQILTRTGEWNGAAASAALRGTVHDRWIEARKAAQHLVDDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAVNARAARGIDDAVNAAKIGIEAALIVALVVAIVCGYLLLRAITVPMQSIVNLLSGIRG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLRLRMALRRKDEFQEVEAGFNQMTGELTSLVGQAQRTAIQVTTSVNEIAATARQQQAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
ATETAATTTQIGATSREISATARDLVRTIHEVSSAAEQAAGLAGTGQVGLSRMEGTMQHV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MDAAGSVNAKLATLNEKASNINQVVTTIAKVADQTNLLSLNAAIEAEKAGEYGRGFAVVA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHH
TEIRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMSEVTQVGDQLSQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVQSLAPRVLMVNEGMQAQAGGAEQINQALMQLSEAAQQTVESLRQSSQAIDELTLVAN
HHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRSGVSRFKV
HHHHHHHHCCC
>Mature Secondary Structure 
AAPEQEHHRDHTVNEWTIRTRILASFSLILLVMALMGVVSYTRLSAIERETTLMLKDAL
CCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLNHSTGIRGIWGERYVLAWQTINAADEAERRSFQQQGQDAASRLDKVEQQYETSITRD
CCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
EDRAAFRAYRDVRAQYEQAAQILTRTGEWNGAAASAALRGTVHDRWIEARKAAQHLVDDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAVNARAARGIDDAVNAAKIGIEAALIVALVVAIVCGYLLLRAITVPMQSIVNLLSGIRG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLRLRMALRRKDEFQEVEAGFNQMTGELTSLVGQAQRTAIQVTTSVNEIAATARQQQAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
ATETAATTTQIGATSREISATARDLVRTIHEVSSAAEQAAGLAGTGQVGLSRMEGTMQHV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MDAAGSVNAKLATLNEKASNINQVVTTIAKVADQTNLLSLNAAIEAEKAGEYGRGFAVVA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHH
TEIRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMSEVTQVGDQLSQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVQSLAPRVLMVNEGMQAQAGGAEQINQALMQLSEAAQQTVESLRQSSQAIDELTLVAN
HHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRSGVSRFKV
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]