| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is livF [H]
Identifier: 116695976
GI number: 116695976
Start: 2292749
End: 2293456
Strand: Direct
Name: livF [H]
Synonym: H16_B2040
Alternate gene names: 116695976
Gene position: 2292749-2293456 (Clockwise)
Preceding gene: 116695975
Following gene: 116695977
Centisome position: 78.72
GC content: 67.37
Gene sequence:
>708_bases ATGTTGCAGCTTGAACGCGTCTCGCTGTCGTACGGCAGCTTCCGCGCCCTCGACAACATCACCCTGCACGCCGGCGCCGG CGAGCTGGTGGTGCTGCTGGGCGCCAACGGCGCCGGCAAGAGCTCGATCTTCCTGGCGATGAGCGCGATCCACCGCATCA GCGGTGGCAGCATGCGCTTCGATGGGCGCGAGCTGTCGGGCATGAAGCCGTCGCAGATCGTGCAGGCCGGGCTGGTGCAC TGCCCGGAGGGCCGCAAGCTGTTCCCGGCGATGAGCGTGGAGAAGAACCTGGTGCTGGGCGCCTACGTGCACCGGCGCGA TGGTGCGGGTATCCGCAAGACGCTGGAAGAGGTCTATGAACTGTTCCCGATCCTGCGGCAGAAGAAGGACGACCCGGCCG GCTCGCTGTCCGGCGGGCAGCAGCAGATGGTGGCGCTGGGCCGCGCCCTGATGAGCCGCCCGCGCGCGCTGTTGCTGGAC GAGCCGTCGCTGGGGCTGGCGCCGCTGGTGGTCAAGCAGATGTTCGAGATCATCCAGCGCATCAACCGTGCCGGCACCAC CGTGCTGCTGGCCGAGCAGAACGCCTACGCGGCGCTGGGCATCGCGCATCGCGCCTATGTGATCGAGAGCGGGCGCATCG TGATGGAGGGGGATCGGGATACGTTGCTGAAGGATGAGGGGATTCGGAAGGCGTATATCGGGGGGTAG
Upstream 100 bases:
>100_bases AAGATCATGGTGCTGAACTACGGCGAGAAGATTGCCGAAGGCACGCCCGCGCAGATCCAGCAGGATCCGCATGTCATCGA GGCCTACCTGGGAGCCGACC
Downstream 100 bases:
>100_bases GTTCAGAGGAGCCGGCCTCGCGACAGCAAAACACAACCAGACCTAGCAAGTGCAGTACTTTCAGGAGACATAGCAATGCA AAGCAAGATCATGCGCCGTA
Product: ABC transporter ATPase
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 235; Mature: 235
Protein sequence:
>235_residues MLQLERVSLSYGSFRALDNITLHAGAGELVVLLGANGAGKSSIFLAMSAIHRISGGSMRFDGRELSGMKPSQIVQAGLVH CPEGRKLFPAMSVEKNLVLGAYVHRRDGAGIRKTLEEVYELFPILRQKKDDPAGSLSGGQQQMVALGRALMSRPRALLLD EPSLGLAPLVVKQMFEIIQRINRAGTTVLLAEQNAYAALGIAHRAYVIESGRIVMEGDRDTLLKDEGIRKAYIGG
Sequences:
>Translated_235_residues MLQLERVSLSYGSFRALDNITLHAGAGELVVLLGANGAGKSSIFLAMSAIHRISGGSMRFDGRELSGMKPSQIVQAGLVH CPEGRKLFPAMSVEKNLVLGAYVHRRDGAGIRKTLEEVYELFPILRQKKDDPAGSLSGGQQQMVALGRALMSRPRALLLD EPSLGLAPLVVKQMFEIIQRINRAGTTVLLAEQNAYAALGIAHRAYVIESGRIVMEGDRDTLLKDEGIRKAYIGG >Mature_235_residues MLQLERVSLSYGSFRALDNITLHAGAGELVVLLGANGAGKSSIFLAMSAIHRISGGSMRFDGRELSGMKPSQIVQAGLVH CPEGRKLFPAMSVEKNLVLGAYVHRRDGAGIRKTLEEVYELFPILRQKKDDPAGSLSGGQQQMVALGRALMSRPRALLLD EPSLGLAPLVVKQMFEIIQRINRAGTTVLLAEQNAYAALGIAHRAYVIESGRIVMEGDRDTLLKDEGIRKAYIGG
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI45446740, Length=221, Percent_Identity=28.0542986425339, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI47078218, Length=221, Percent_Identity=28.0542986425339, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI27436953, Length=208, Percent_Identity=27.8846153846154, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI27477115, Length=213, Percent_Identity=27.2300469483568, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI153792144, Length=219, Percent_Identity=26.9406392694064, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI31657092, Length=219, Percent_Identity=25.1141552511416, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI27881501, Length=214, Percent_Identity=24.7663551401869, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI30795238, Length=214, Percent_Identity=24.7663551401869, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI9961250, Length=239, Percent_Identity=26.7782426778243, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI4505771, Length=239, Percent_Identity=26.7782426778243, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI9961252, Length=239, Percent_Identity=26.7782426778243, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI27262624, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI27262626, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=22.7722772277228, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=22.2772277227723, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI116734710, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI156105685, Length=234, Percent_Identity=26.0683760683761, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI150417984, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI42741659, Length=239, Percent_Identity=26.7782426778243, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI9955963, Length=239, Percent_Identity=26.7782426778243, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI87082268, Length=235, Percent_Identity=43.8297872340426, Blast_Score=220, Evalue=5e-59, Organism=Escherichia coli, GI1789864, Length=254, Percent_Identity=27.9527559055118, Blast_Score=110, Evalue=6e-26, Organism=Escherichia coli, GI1789593, Length=235, Percent_Identity=28.936170212766, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=29.5652173913043, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI1787089, Length=226, Percent_Identity=33.1858407079646, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI87081791, Length=238, Percent_Identity=29.8319327731092, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1786398, Length=215, Percent_Identity=30.6976744186047, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=30.2222222222222, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786872, Length=229, Percent_Identity=29.6943231441048, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1788450, Length=224, Percent_Identity=28.125, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI87082267, Length=215, Percent_Identity=31.6279069767442, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789873, Length=211, Percent_Identity=29.8578199052133, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1787712, Length=241, Percent_Identity=29.045643153527, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1790467, Length=217, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1790190, Length=230, Percent_Identity=26.0869565217391, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1788210, Length=206, Percent_Identity=32.0388349514563, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1787792, Length=221, Percent_Identity=28.0542986425339, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=27.4678111587983, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI48995001, Length=224, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=27.8260869565217, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI48994943, Length=199, Percent_Identity=32.6633165829146, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1789991, Length=232, Percent_Identity=27.1551724137931, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787370, Length=218, Percent_Identity=27.0642201834862, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1788472, Length=216, Percent_Identity=24.0740740740741, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=30.6666666666667, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786253, Length=240, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=30, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787164, Length=213, Percent_Identity=30.9859154929577, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1790162, Length=246, Percent_Identity=24.7967479674797, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1788897, Length=211, Percent_Identity=25.1184834123223, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=31.0185185185185, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1790525, Length=228, Percent_Identity=21.9298245614035, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1786698, Length=205, Percent_Identity=29.7560975609756, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI87081782, Length=216, Percent_Identity=26.8518518518519, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87081834, Length=224, Percent_Identity=25, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1788165, Length=188, Percent_Identity=27.1276595744681, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1788053, Length=164, Percent_Identity=33.5365853658537, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=26.457399103139, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI48994883, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1788506, Length=213, Percent_Identity=24.4131455399061, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI48994997, Length=236, Percent_Identity=23.3050847457627, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1786975, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1786803, Length=233, Percent_Identity=24.0343347639485, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789032, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789963, Length=237, Percent_Identity=23.6286919831224, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1787113, Length=207, Percent_Identity=31.4009661835749, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI1789586, Length=233, Percent_Identity=24.8927038626609, Blast_Score=60, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17565586, Length=204, Percent_Identity=31.3725490196078, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17510237, Length=221, Percent_Identity=25.3393665158371, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71983523, Length=215, Percent_Identity=26.9767441860465, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI71983516, Length=215, Percent_Identity=26.9767441860465, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI71983510, Length=215, Percent_Identity=26.9767441860465, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI115533608, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=1e-15, Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71984940, Length=223, Percent_Identity=26.9058295964126, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193209708, Length=241, Percent_Identity=26.9709543568465, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI115533592, Length=237, Percent_Identity=25.3164556962025, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI25146777, Length=219, Percent_Identity=24.2009132420091, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17565938, Length=233, Percent_Identity=24.4635193133047, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17541710, Length=219, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17558664, Length=220, Percent_Identity=24.5454545454545, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17569145, Length=216, Percent_Identity=24.537037037037, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17569143, Length=216, Percent_Identity=25.462962962963, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24643674, Length=210, Percent_Identity=26.1904761904762, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI221500365, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI116007184, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI221512771, Length=218, Percent_Identity=26.1467889908257, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24666092, Length=212, Percent_Identity=24.0566037735849, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI28573573, Length=203, Percent_Identity=29.064039408867, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28573571, Length=203, Percent_Identity=29.064039408867, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24641565, Length=234, Percent_Identity=25.2136752136752, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24648314, Length=220, Percent_Identity=23.1818181818182, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24650853, Length=209, Percent_Identity=23.9234449760766, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24650855, Length=210, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28574150, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI116007328, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI281362751, Length=207, Percent_Identity=24.1545893719807, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574744, Length=228, Percent_Identity=24.5614035087719, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI28574533, Length=225, Percent_Identity=22.6666666666667, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 25409; Mature: 25409
Theoretical pI: Translated: 10.00; Mature: 10.00
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLQLERVSLSYGSFRALDNITLHAGAGELVVLLGANGAGKSSIFLAMSAIHRISGGSMRF CCEEEEEECCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE DGRELSGMKPSQIVQAGLVHCPEGRKLFPAMSVEKNLVLGAYVHRRDGAGIRKTLEEVYE CCCCCCCCCHHHHHHHHCEECCCCCEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH LFPILRQKKDDPAGSLSGGQQQMVALGRALMSRPRALLLDEPSLGLAPLVVKQMFEIIQR HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHH INRAGTTVLLAEQNAYAALGIAHRAYVIESGRIVMEGDRDTLLKDEGIRKAYIGG HHCCCCEEEEECCCCEEEHHHHHEEEEEECCEEEEECCCCCCCCCCCCCEECCCC >Mature Secondary Structure MLQLERVSLSYGSFRALDNITLHAGAGELVVLLGANGAGKSSIFLAMSAIHRISGGSMRF CCEEEEEECCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE DGRELSGMKPSQIVQAGLVHCPEGRKLFPAMSVEKNLVLGAYVHRRDGAGIRKTLEEVYE CCCCCCCCCHHHHHHHHCEECCCCCEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH LFPILRQKKDDPAGSLSGGQQQMVALGRALMSRPRALLLDEPSLGLAPLVVKQMFEIIQR HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHH INRAGTTVLLAEQNAYAALGIAHRAYVIESGRIVMEGDRDTLLKDEGIRKAYIGG HHCCCCEEEEECCCCEEEHHHHHEEEEEECCEEEEECCCCCCCCCCCCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]