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The map label for this gene is qor [C]

Identifier: 116695940

GI number: 116695940

Start: 2262590

End: 2263600

Strand: Direct

Name: qor [C]

Synonym: H16_B2004

Alternate gene names: 116695940

Gene position: 2262590-2263600 (Clockwise)

Preceding gene: 116695939

Following gene: 116695941

Centisome position: 77.69

GC content: 70.43

Gene sequence:

>1011_bases
ATGAAGGCGCTTGTCTGCAAGCAGTTCGGCGGCGTGCAGGACGTGGCGCTGCAGGCCATCCCGGAACCGGTGCTGGCCGA
CCCGCATGCGGTCACGATTGCCGTCGAGTACGCCAGCGTCAGCCACGCCACCGGCCTGATGATCGCCGGCCAGTACCAGC
GCCGGCCCCCGTTGCCCTTCGTGCCCGGTACCGAAGCGGTCGGCCGCGTGGTGGCCTGCGGTGACGCGTGCACGCGGCTG
CGTCCCGGCGACCGGGTGGTGGCGATCGCGGACTGGGGCTGCTTTGCCGAACAGGTCACCGTGCCCGAGTACACCGTCTA
CCGCGTCCCGGATGCGCTGCCGTCAAAGGCCGCGCTGCCGATCCCGATTTCCTATGGCACGGCGTATTGCGGGCTGGTGT
GGCGCTGCGCGCTGCGCCCGAATGACACGGTGCTGGTGCTTGGCGCCGGGGCCGGTGTCGGCCTGGCTGCCGTGGAAATT
GCGCGCCAGCTCGGCGCCACCGTCATCGCCTGCGCCAGCACCGAGGCCAAGCGTGCCGACGCGCTGCGGCGCGGCGCCAC
GCACGCGCTGGCCCCGGCGGACCTGGCGGCATCGGTCAAGGCGCTGACGCACGGCCGTGGCGCGGACGTAGTGGTGGACC
CGGTCGGCGGCGACCTGTTCAACCAGGCCCTGCGTGCGGCGGCGGCGAACGCGCGCATCCTCAGCATCGGCTTTGCCAGC
GGCACCATCCCGCAGGCCCCGGTCAACCTGCTGCTGGTCAAGAACCTCACGCTGCACGGGTTCTTCTTTGGCCGCTACAT
CGGCTGGACGCCCGCCAACGAGCGGGCCGAGCATGCAACGGCGCTGCAGGAGGTCATGGCGACGCTGTTCGATTGGGCCG
CGCGGGGCAAGCTGGAGCCGACCGTATCCGCGGTCTATCCGATCACCGGCCTGGACGACGCCCTGGCCGCGCTGGAATCC
CGCCAGGTGGTGGGCAAGGTAGCCATAAAAATCAAGGAGACAGAGACGTGA

Upstream 100 bases:

>100_bases
TCCTGCGCGAGGCCGGCTTCGGCCAGCAGGCCATCGACGCATGGCTGCAGCAGGGTGTGGTGCGACAGGCGACGGCCCCC
GCGGCCAAGGCAGGTGTGCA

Downstream 100 bases:

>100_bases
ACAACCGATACCAGAAACGACTTCCGGCTTGGCCGCGGCTGCGCGCGGCACTGATGCTGGCGGCAGCCGCGGCCGCGCTG
CCGGCTGCCGCCGTCGCGCA

Product: NADPH:quinone reductase or related Zn-dependent oxidoreductase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKALVCKQFGGVQDVALQAIPEPVLADPHAVTIAVEYASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGDACTRL
RPGDRVVAIADWGCFAEQVTVPEYTVYRVPDALPSKAALPIPISYGTAYCGLVWRCALRPNDTVLVLGAGAGVGLAAVEI
ARQLGATVIACASTEAKRADALRRGATHALAPADLAASVKALTHGRGADVVVDPVGGDLFNQALRAAAANARILSIGFAS
GTIPQAPVNLLLVKNLTLHGFFFGRYIGWTPANERAEHATALQEVMATLFDWAARGKLEPTVSAVYPITGLDDALAALES
RQVVGKVAIKIKETET

Sequences:

>Translated_336_residues
MKALVCKQFGGVQDVALQAIPEPVLADPHAVTIAVEYASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGDACTRL
RPGDRVVAIADWGCFAEQVTVPEYTVYRVPDALPSKAALPIPISYGTAYCGLVWRCALRPNDTVLVLGAGAGVGLAAVEI
ARQLGATVIACASTEAKRADALRRGATHALAPADLAASVKALTHGRGADVVVDPVGGDLFNQALRAAAANARILSIGFAS
GTIPQAPVNLLLVKNLTLHGFFFGRYIGWTPANERAEHATALQEVMATLFDWAARGKLEPTVSAVYPITGLDDALAALES
RQVVGKVAIKIKETET
>Mature_336_residues
MKALVCKQFGGVQDVALQAIPEPVLADPHAVTIAVEYASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGDACTRL
RPGDRVVAIADWGCFAEQVTVPEYTVYRVPDALPSKAALPIPISYGTAYCGLVWRCALRPNDTVLVLGAGAGVGLAAVEI
ARQLGATVIACASTEAKRADALRRGATHALAPADLAASVKALTHGRGADVVVDPVGGDLFNQALRAAAANARILSIGFAS
GTIPQAPVNLLLVKNLTLHGFFFGRYIGWTPANERAEHATALQEVMATLFDWAARGKLEPTVSAVYPITGLDDALAALES
RQVVGKVAIKIKETET

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=318, Percent_Identity=28.3018867924528, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI13236495, Length=318, Percent_Identity=28.3018867924528, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI18379349, Length=351, Percent_Identity=28.4900284900285, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI194239676, Length=188, Percent_Identity=35.6382978723404, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI24308257, Length=356, Percent_Identity=25.561797752809, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI67078406, Length=294, Percent_Identity=28.9115646258503, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI67078404, Length=294, Percent_Identity=28.9115646258503, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=24.1071428571429, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=24.1071428571429, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI28557745, Length=307, Percent_Identity=28.3387622149837, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41872631, Length=314, Percent_Identity=24.5222929936306, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=29.0519877675841, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789651, Length=269, Percent_Identity=27.5092936802974, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=310, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=338, Percent_Identity=27.2189349112426, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19920632, Length=319, Percent_Identity=22.884012539185, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24581345, Length=288, Percent_Identity=24.6527777777778, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330659, Length=319, Percent_Identity=22.884012539185, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 35134; Mature: 35134

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVCKQFGGVQDVALQAIPEPVLADPHAVTIAVEYASVSHATGLMIAGQYQRRPPLPF
CCCCHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCC
VPGTEAVGRVVACGDACTRLRPGDRVVAIADWGCFAEQVTVPEYTVYRVPDALPSKAALP
CCCCHHHHHEEECCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCE
IPISYGTAYCGLVWRCALRPNDTVLVLGAGAGVGLAAVEIARQLGATVIACASTEAKRAD
EEECCCCHHHHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCHHHHH
ALRRGATHALAPADLAASVKALTHGRGADVVVDPVGGDLFNQALRAAAANARILSIGFAS
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCC
GTIPQAPVNLLLVKNLTLHGFFFGRYIGWTPANERAEHATALQEVMATLFDWAARGKLEP
CCCCCCCCEEEEEECCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVSAVYPITGLDDALAALESRQVVGKVAIKIKETET
CCEEEECCCCCHHHHHHHHHHHEEEEEEEEEEECCC
>Mature Secondary Structure
MKALVCKQFGGVQDVALQAIPEPVLADPHAVTIAVEYASVSHATGLMIAGQYQRRPPLPF
CCCCHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCC
VPGTEAVGRVVACGDACTRLRPGDRVVAIADWGCFAEQVTVPEYTVYRVPDALPSKAALP
CCCCHHHHHEEECCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCE
IPISYGTAYCGLVWRCALRPNDTVLVLGAGAGVGLAAVEIARQLGATVIACASTEAKRAD
EEECCCCHHHHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCHHHHH
ALRRGATHALAPADLAASVKALTHGRGADVVVDPVGGDLFNQALRAAAANARILSIGFAS
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCC
GTIPQAPVNLLLVKNLTLHGFFFGRYIGWTPANERAEHATALQEVMATLFDWAARGKLEP
CCCCCCCCEEEEEECCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVSAVYPITGLDDALAALESRQVVGKVAIKIKETET
CCEEEECCCCCHHHHHHHHHHHEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]