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The map label for this gene is yfdE [H]

Identifier: 116695939

GI number: 116695939

Start: 2261364

End: 2262593

Strand: Direct

Name: yfdE [H]

Synonym: H16_B2003

Alternate gene names: 116695939

Gene position: 2261364-2262593 (Clockwise)

Preceding gene: 116695937

Following gene: 116695940

Centisome position: 77.64

GC content: 70.41

Gene sequence:

>1230_bases
ATGTCCGCACTGCCCGCTTCCGACCTGTCCGACACCGACCTGCCTTTCGCCGGCCTGCGCGTGCTCGACATCAGCCAGGG
CATTGCCGGCCCGTATTGCGCGCACATCCTGTGGCAGCAAGGCGCTGGAATCGTCAAGGTCGAGCCGCCCGCGGGCGACT
GGGGCCGCAAGGTCGGGGTCGTGCGCGGCGATACCAGCGCGCTGGCGATCGCCTATAACGCCGGCAAGCGCAGCGCCTGC
ATCGACGCCACCACTGACGCCGGCAAGGAGGTGCTGCTCGGCCTTGCGCTGCAGGCGGACATCGTCGTGCAGAACTTCCG
CCCTCAAGTGGCGGAACGGCTGGGCGTGGGCTATGCGGCGCTGGCCGCGCAGCGGCCAGCGCTGATCTATGTGTCGATCA
GCGGCTATGGCCCGGATGGTCCCTATGCCGACTATCCGGCTTCGGACTCGGTGATGCAGGCCGACTCCGGGCTGATGTTC
GCCAACCGTGGCGCCGACGGTGGCGCGCGCCGCATCGGCATGCTGCTCGCCGACGCCGCCACCGGCCTCTATGCCGCCCA
GGCCTGCGCCGCGGCGCTGTGCCGGCGTTTTCGCAGCGGGCTCGGCGGCCATGTCGAGCTGAACCTGTTCGATGCCTGCT
GTGCGCTGCAGGCCAACAACCTGCTCGAGCATGCCATCGGTGGTCCGACGGCCGCCGGCCCGGTGAGCGCGCCCAATGGC
GTCTATGCCAGCAGCGACGGCAGCGTGACGCTGCTGGCGCTGAACAACGCGCAGTTCGCCAAGCTATGCCATGCGCTGGA
CCGCACCGGCTGGCTGGAAGACCCGCGCTTTGCCGACAATGCCGCGCGCATGGCCCACGCCGCGCTGCTGAACCAGCAGG
TGGCCGAGCAGATCGCCACGCGCACGACCGCGCAATGGCAAGACATCCTCAGCCGGCACGACGTGCTGCATGCCCCGGTG
CGCAGCTATGACGACGTGCTGGCGCACCCGCAGGCGGCATACCGGCAGACCTTCCAGACGATCGCGCAGCCGGGGCTCGG
ACCGCTGCCCTTCGCCGGCATCCCGGCGCGCGACATGCGCCGGGATGCCGGCCCGGCGCCGGCCAACGGCGAACATACCG
TGCAGGTCCTGCGCGAGGCCGGCTTCGGCCAGCAGGCCATCGACGCATGGCTGCAGCAGGGTGTGGTGCGACAGGCGACG
GCCCCCGCGGCCAAGGCAGGTGTGCAATGA

Upstream 100 bases:

>100_bases
TGTCAATCATGAGTCAACACCGTAGGCACAAATCGAGGGATTGTCCTGGCAGGAAGCCAACCCTAGCATAAACCTCCTGC
TTACCCACCTTTCGAACGCC

Downstream 100 bases:

>100_bases
AGGCGCTTGTCTGCAAGCAGTTCGGCGGCGTGCAGGACGTGGCGCTGCAGGCCATCCCGGAACCGGTGCTGGCCGACCCG
CATGCGGTCACGATTGCCGT

Product: acyl-CoA transferase/carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSALPASDLSDTDLPFAGLRVLDISQGIAGPYCAHILWQQGAGIVKVEPPAGDWGRKVGVVRGDTSALAIAYNAGKRSAC
IDATTDAGKEVLLGLALQADIVVQNFRPQVAERLGVGYAALAAQRPALIYVSISGYGPDGPYADYPASDSVMQADSGLMF
ANRGADGGARRIGMLLADAATGLYAAQACAAALCRRFRSGLGGHVELNLFDACCALQANNLLEHAIGGPTAAGPVSAPNG
VYASSDGSVTLLALNNAQFAKLCHALDRTGWLEDPRFADNAARMAHAALLNQQVAEQIATRTTAQWQDILSRHDVLHAPV
RSYDDVLAHPQAAYRQTFQTIAQPGLGPLPFAGIPARDMRRDAGPAPANGEHTVQVLREAGFGQQAIDAWLQQGVVRQAT
APAAKAGVQ

Sequences:

>Translated_409_residues
MSALPASDLSDTDLPFAGLRVLDISQGIAGPYCAHILWQQGAGIVKVEPPAGDWGRKVGVVRGDTSALAIAYNAGKRSAC
IDATTDAGKEVLLGLALQADIVVQNFRPQVAERLGVGYAALAAQRPALIYVSISGYGPDGPYADYPASDSVMQADSGLMF
ANRGADGGARRIGMLLADAATGLYAAQACAAALCRRFRSGLGGHVELNLFDACCALQANNLLEHAIGGPTAAGPVSAPNG
VYASSDGSVTLLALNNAQFAKLCHALDRTGWLEDPRFADNAARMAHAALLNQQVAEQIATRTTAQWQDILSRHDVLHAPV
RSYDDVLAHPQAAYRQTFQTIAQPGLGPLPFAGIPARDMRRDAGPAPANGEHTVQVLREAGFGQQAIDAWLQQGVVRQAT
APAAKAGVQ
>Mature_408_residues
SALPASDLSDTDLPFAGLRVLDISQGIAGPYCAHILWQQGAGIVKVEPPAGDWGRKVGVVRGDTSALAIAYNAGKRSACI
DATTDAGKEVLLGLALQADIVVQNFRPQVAERLGVGYAALAAQRPALIYVSISGYGPDGPYADYPASDSVMQADSGLMFA
NRGADGGARRIGMLLADAATGLYAAQACAAALCRRFRSGLGGHVELNLFDACCALQANNLLEHAIGGPTAAGPVSAPNGV
YASSDGSVTLLALNNAQFAKLCHALDRTGWLEDPRFADNAARMAHAALLNQQVAEQIATRTTAQWQDILSRHDVLHAPVR
SYDDVLAHPQAAYRQTFQTIAQPGLGPLPFAGIPARDMRRDAGPAPANGEHTVQVLREAGFGQQAIDAWLQQGVVRQATA
PAAKAGVQ

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=406, Percent_Identity=30.2955665024631, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI300863124, Length=432, Percent_Identity=28.9351851851852, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI300863126, Length=400, Percent_Identity=26.75, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI13376042, Length=432, Percent_Identity=26.6203703703704, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI42794625, Length=383, Percent_Identity=27.9373368146214, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI266456254, Length=383, Percent_Identity=27.9373368146214, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI266458393, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI266458397, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI266458395, Length=144, Percent_Identity=31.9444444444444, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI42822893, Length=144, Percent_Identity=31.9444444444444, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082093, Length=348, Percent_Identity=33.3333333333333, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1788717, Length=414, Percent_Identity=25.8454106280193, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786222, Length=408, Percent_Identity=21.5686274509804, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648431, Length=400, Percent_Identity=32, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24585488, Length=338, Percent_Identity=25.1479289940828, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 42705; Mature: 42573

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALPASDLSDTDLPFAGLRVLDISQGIAGPYCAHILWQQGAGIVKVEPPAGDWGRKVGV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHCEEEE
VRGDTSALAIAYNAGKRSACIDATTDAGKEVLLGLALQADIVVQNFRPQVAERLGVGYAA
EECCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
LAAQRPALIYVSISGYGPDGPYADYPASDSVMQADSGLMFANRGADGGARRIGMLLADAA
HHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
TGLYAAQACAAALCRRFRSGLGGHVELNLFDACCALQANNLLEHAIGGPTAAGPVSAPNG
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VYASSDGSVTLLALNNAQFAKLCHALDRTGWLEDPRFADNAARMAHAALLNQQVAEQIAT
EEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RTTAQWQDILSRHDVLHAPVRSYDDVLAHPQAAYRQTFQTIAQPGLGPLPFAGIPARDMR
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RDAGPAPANGEHTVQVLREAGFGQQAIDAWLQQGVVRQATAPAAKAGVQ
HCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCHHHCCCC
>Mature Secondary Structure 
SALPASDLSDTDLPFAGLRVLDISQGIAGPYCAHILWQQGAGIVKVEPPAGDWGRKVGV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHCEEEE
VRGDTSALAIAYNAGKRSACIDATTDAGKEVLLGLALQADIVVQNFRPQVAERLGVGYAA
EECCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
LAAQRPALIYVSISGYGPDGPYADYPASDSVMQADSGLMFANRGADGGARRIGMLLADAA
HHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
TGLYAAQACAAALCRRFRSGLGGHVELNLFDACCALQANNLLEHAIGGPTAAGPVSAPNG
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VYASSDGSVTLLALNNAQFAKLCHALDRTGWLEDPRFADNAARMAHAALLNQQVAEQIAT
EEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RTTAQWQDILSRHDVLHAPVRSYDDVLAHPQAAYRQTFQTIAQPGLGPLPFAGIPARDMR
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RDAGPAPANGEHTVQVLREAGFGQQAIDAWLQQGVVRQATAPAAKAGVQ
HCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]