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The map label for this gene is yrhP [H]

Identifier: 116695915

GI number: 116695915

Start: 2237046

End: 2237663

Strand: Direct

Name: yrhP [H]

Synonym: H16_B1979

Alternate gene names: 116695915

Gene position: 2237046-2237663 (Clockwise)

Preceding gene: 116695914

Following gene: 116695917

Centisome position: 76.81

GC content: 64.24

Gene sequence:

>618_bases
ATGTCATTCATCCCCTTCCTGATCGCAGCCATCGTTCTCGCCATCACCCCCGGCCCGGCCATCGCCTATGTCGTTGCACG
AACGGTGGCTGGCGGCCGATCCGCAGGCCTGGCTTCATGCTTCGGCACCGCCCTCGGAGGCTTGCTCCATGTGCTCGCGG
CAGCCTTGGGCCTGTCGCTGGTCATTGCCCAGTCGGCCGTGGCATTCAACCTGCTCAAGTATCTGGGTGCTGCTTATCTG
GTGTACCTGGGGATTCGCATGCTGATGCGCAAGCAGGCGCCGGTCACGCTCGAAACCATGCCATCCAGAGGTGCGCGCCG
CGCTCTGGTCGAGGGCATCATGGTCGAGGTCCTGAACGTCAAGACGGCGCTGTTCTTTCTGGCGTTCCTGCCGCAGTTTG
TCTCGGCGAGCGAAGCTCTGGTGCCGCAGTTGGTGCTGTTGGGCTGCATTTGCGTCGCGCTCAATACGCTGGTCGACGTT
GTTGTCGTGTTTGCCGCGCATCGTCTGCTCAAGTCCGGCGCCGCCCGCGAAGCTCGCGCCCGCTTGATGACCCGGATGTC
GGGCGTGACGATGCTGGGCCTGGGCGCCATTCTGGCGCTCGCCCGGCGCGAAGCATAG

Upstream 100 bases:

>100_bases
CGCGGGGGTATGGCGAACTTGCGCAGTCCATGCGCAAGGCTGGTTGAATTGCCCCCGGGCCCGCGCTCAGCTTTTCCTCA
CCATTGACGAATACCCCGCC

Downstream 100 bases:

>100_bases
ACAGGGGGGCGGTTCGGCGCAGGGCTCGAACCGCCCGCCCCTCAAGCAGCAGCCCGCCGGGCCGCGCCGCGATACTGCGC
CAGCAACGCGTCCCGCCGTA

Product: putative threonine efflux protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSFIPFLIAAIVLAITPGPAIAYVVARTVAGGRSAGLASCFGTALGGLLHVLAAALGLSLVIAQSAVAFNLLKYLGAAYL
VYLGIRMLMRKQAPVTLETMPSRGARRALVEGIMVEVLNVKTALFFLAFLPQFVSASEALVPQLVLLGCICVALNTLVDV
VVVFAAHRLLKSGAAREARARLMTRMSGVTMLGLGAILALARREA

Sequences:

>Translated_205_residues
MSFIPFLIAAIVLAITPGPAIAYVVARTVAGGRSAGLASCFGTALGGLLHVLAAALGLSLVIAQSAVAFNLLKYLGAAYL
VYLGIRMLMRKQAPVTLETMPSRGARRALVEGIMVEVLNVKTALFFLAFLPQFVSASEALVPQLVLLGCICVALNTLVDV
VVVFAAHRLLKSGAAREARARLMTRMSGVTMLGLGAILALARREA
>Mature_204_residues
SFIPFLIAAIVLAITPGPAIAYVVARTVAGGRSAGLASCFGTALGGLLHVLAAALGLSLVIAQSAVAFNLLKYLGAAYLV
YLGIRMLMRKQAPVTLETMPSRGARRALVEGIMVEVLNVKTALFFLAFLPQFVSASEALVPQLVLLGCICVALNTLVDVV
VVFAAHRLLKSGAAREARARLMTRMSGVTMLGLGAILALARREA

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=203, Percent_Identity=27.0935960591133, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788099, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21434; Mature: 21303

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIPFLIAAIVLAITPGPAIAYVVARTVAGGRSAGLASCFGTALGGLLHVLAAALGLSL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIAQSAVAFNLLKYLGAAYLVYLGIRMLMRKQAPVTLETMPSRGARRALVEGIMVEVLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KTALFFLAFLPQFVSASEALVPQLVLLGCICVALNTLVDVVVVFAAHRLLKSGAAREARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLMTRMSGVTMLGLGAILALARREA
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFIPFLIAAIVLAITPGPAIAYVVARTVAGGRSAGLASCFGTALGGLLHVLAAALGLSL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIAQSAVAFNLLKYLGAAYLVYLGIRMLMRKQAPVTLETMPSRGARRALVEGIMVEVLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KTALFFLAFLPQFVSASEALVPQLVLLGCICVALNTLVDVVVVFAAHRLLKSGAAREARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLMTRMSGVTMLGLGAILALARREA
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]