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The map label for this gene is paaJ [C]

Identifier: 116695839

GI number: 116695839

Start: 2149834

End: 2150979

Strand: Direct

Name: paaJ [C]

Synonym: H16_B1903

Alternate gene names: 116695839

Gene position: 2149834-2150979 (Clockwise)

Preceding gene: 116695838

Following gene: 116695840

Centisome position: 73.81

GC content: 70.16

Gene sequence:

>1146_bases
ATGCAGGACATCTACATCCATGGCGGCGCGATGACGCCGTTCGGCCGGCACCCCGGCGTGCTGGCGCCGGAGCTGGCGCA
ACAGGCAATCCTGAAGGCGCTGGCCGATGCCGACGTGCCGGCCGGCCGCATCCAGGCGGTCTACTGCGCCAACGTCCTGG
GCGGCATGATCCTCGGCCAGCTGATCGTGCGCGATCTGGGGCTCAAGGGCATCCCGGTCTACAACGTCGAGAACGCCTGC
GCCAGCGGCGCCACCGGCGTGCACCTGGCACGGCACGCGCTGCTGGCCGGGCAATACGACACGGTGCTGGTCTTCGGCAT
CGAGCAGCTGACCGCGCTCGGCGGCGGCACCATCCCGCTGCAGCGCAATGACCACAAGACCGACCTCTATGCGAAGTCCG
GCATGGTACTGCCCGCGGTGTATGCGATGCGCGGCACGCGTTTCCTGCACGAGCGCGACGCCAATCCGTCCGACCTCGCT
GAAGTGGCCGTGAAGAACCGCTACCACGGCTCGCTGAACCCGTATGCCCAGCAGCGCAAGACCACCACGGTCGAGGAAGT
GCTGGCCTCGCGCATGATCGCCGACCCGCTGACGCTGCTGCAGTGCTGCCCGTCGCAGGTCGATGGCGCGGCGTCGGTGG
TGCTGAGCACGCGCCGGCCGGCGCAGGCGCGGCCGGTGAAGGTGCTGTCGTCTGTAGTGGTGTCGGGCATGCGCGAGGAG
GCCGACGACGATATCCTCGATGCCGAGATCACCGCGCGCGCCGCGCGCCAGGCTTACGAACAGGCCGGGCTCGGCCCGCA
GGACGTCGACGTGGTCGAACTGCACGACGCCTTCACCATCGCCGAACTGCTCTACTACGAAGCCCTCGGCCTGGCACCGC
GTGGCGATGCCGTGGCGCTGCTCAAGTCCGGCGCGACGCGCCTGGGCGGGCGCGTGCCGGTCAACCCGAGCGGCGGCCTG
CTGGCCAAGGGGCATCCGCTGGGCGCCACCGGCGTGGCGCAGATGGTCGAGATCCTGTGGCAGCTGCAAGGCCGCGCCGG
CGAACGCCAGGTGGCGGATACCCGCATCGGCCTGACGCAATGCACCGGCGGCGGCATCGCGGGCGTGGACCACGCCGCTT
CTTCCGTCCACCTGCTGGGAGTCTGA

Upstream 100 bases:

>100_bases
GTCATCGGCGAACGCTACGCGCAGCGGCATGACGCCGAGCTGGGCTATGTCTTCGAGGCCGTCACGGTCTGATCGATCGA
GAGAAGGAGAGGTAAGCAAG

Downstream 100 bases:

>100_bases
GATGGGCACGCAACGCTTCGATCCTTCCCATGTGGCGGTGGTCACCGGCGCAGCGCGCGGCATCGGCCTGGGCATCGCCA
CGCAACTGGCCCGCCAGGGG

Product: lipid-transfer protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MQDIYIHGGAMTPFGRHPGVLAPELAQQAILKALADADVPAGRIQAVYCANVLGGMILGQLIVRDLGLKGIPVYNVENAC
ASGATGVHLARHALLAGQYDTVLVFGIEQLTALGGGTIPLQRNDHKTDLYAKSGMVLPAVYAMRGTRFLHERDANPSDLA
EVAVKNRYHGSLNPYAQQRKTTTVEEVLASRMIADPLTLLQCCPSQVDGAASVVLSTRRPAQARPVKVLSSVVVSGMREE
ADDDILDAEITARAARQAYEQAGLGPQDVDVVELHDAFTIAELLYYEALGLAPRGDAVALLKSGATRLGGRVPVNPSGGL
LAKGHPLGATGVAQMVEILWQLQGRAGERQVADTRIGLTQCTGGGIAGVDHAASSVHLLGV

Sequences:

>Translated_381_residues
MQDIYIHGGAMTPFGRHPGVLAPELAQQAILKALADADVPAGRIQAVYCANVLGGMILGQLIVRDLGLKGIPVYNVENAC
ASGATGVHLARHALLAGQYDTVLVFGIEQLTALGGGTIPLQRNDHKTDLYAKSGMVLPAVYAMRGTRFLHERDANPSDLA
EVAVKNRYHGSLNPYAQQRKTTTVEEVLASRMIADPLTLLQCCPSQVDGAASVVLSTRRPAQARPVKVLSSVVVSGMREE
ADDDILDAEITARAARQAYEQAGLGPQDVDVVELHDAFTIAELLYYEALGLAPRGDAVALLKSGATRLGGRVPVNPSGGL
LAKGHPLGATGVAQMVEILWQLQGRAGERQVADTRIGLTQCTGGGIAGVDHAASSVHLLGV
>Mature_381_residues
MQDIYIHGGAMTPFGRHPGVLAPELAQQAILKALADADVPAGRIQAVYCANVLGGMILGQLIVRDLGLKGIPVYNVENAC
ASGATGVHLARHALLAGQYDTVLVFGIEQLTALGGGTIPLQRNDHKTDLYAKSGMVLPAVYAMRGTRFLHERDANPSDLA
EVAVKNRYHGSLNPYAQQRKTTTVEEVLASRMIADPLTLLQCCPSQVDGAASVVLSTRRPAQARPVKVLSSVVVSGMREE
ADDDILDAEITARAARQAYEQAGLGPQDVDVVELHDAFTIAELLYYEALGLAPRGDAVALLKSGATRLGGRVPVNPSGGL
LAKGHPLGATGVAQMVEILWQLQGRAGERQVADTRIGLTQCTGGGIAGVDHAASSVHLLGV

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=408, Percent_Identity=36.0294117647059, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI302344760, Length=342, Percent_Identity=36.8421052631579, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI302344767, Length=336, Percent_Identity=36.6071428571429, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI302344762, Length=407, Percent_Identity=32.9238329238329, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI55956775, Length=354, Percent_Identity=31.9209039548023, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17537653, Length=379, Percent_Identity=32.1899736147757, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24585051, Length=383, Percent_Identity=34.4647519582245, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI19921506, Length=385, Percent_Identity=34.025974025974, Blast_Score=221, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40033; Mature: 40033

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIYIHGGAMTPFGRHPGVLAPELAQQAILKALADADVPAGRIQAVYCANVLGGMILGQ
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LIVRDLGLKGIPVYNVENACASGATGVHLARHALLAGQYDTVLVFGIEQLTALGGGTIPL
HHHHHCCCCCCEEECCCHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCCC
QRNDHKTDLYAKSGMVLPAVYAMRGTRFLHERDANPSDLAEVAVKNRYHGSLNPYAQQRK
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
TTTVEEVLASRMIADPLTLLQCCPSQVDGAASVVLSTRRPAQARPVKVLSSVVVSGMREE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHH
ADDDILDAEITARAARQAYEQAGLGPQDVDVVELHDAFTIAELLYYEALGLAPRGDAVAL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHH
LKSGATRLGGRVPVNPSGGLLAKGHPLGATGVAQMVEILWQLQGRAGERQVADTRIGLTQ
HHCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEE
CTGGGIAGVDHAASSVHLLGV
CCCCCCCCHHHCCCCEEEECC
>Mature Secondary Structure
MQDIYIHGGAMTPFGRHPGVLAPELAQQAILKALADADVPAGRIQAVYCANVLGGMILGQ
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LIVRDLGLKGIPVYNVENACASGATGVHLARHALLAGQYDTVLVFGIEQLTALGGGTIPL
HHHHHCCCCCCEEECCCHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCCC
QRNDHKTDLYAKSGMVLPAVYAMRGTRFLHERDANPSDLAEVAVKNRYHGSLNPYAQQRK
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
TTTVEEVLASRMIADPLTLLQCCPSQVDGAASVVLSTRRPAQARPVKVLSSVVVSGMREE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHH
ADDDILDAEITARAARQAYEQAGLGPQDVDVVELHDAFTIAELLYYEALGLAPRGDAVAL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHH
LKSGATRLGGRVPVNPSGGLLAKGHPLGATGVAQMVEILWQLQGRAGERQVADTRIGLTQ
HHCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEE
CTGGGIAGVDHAASSVHLLGV
CCCCCCCCHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]