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The map label for this gene is xdhB2 [H]

Identifier: 116695834

GI number: 116695834

Start: 2144850

End: 2146964

Strand: Direct

Name: xdhB2 [H]

Synonym: H16_B1898

Alternate gene names: 116695834

Gene position: 2144850-2146964 (Clockwise)

Preceding gene: 116695833

Following gene: 116695835

Centisome position: 73.64

GC content: 68.42

Gene sequence:

>2115_bases
ATGAACGCAAACCATATCGGCCAGCCGCATGCCCGCGTCGACGGGCGCGCCAAGGTGACCGGCAGCGCGCGGTATGCCGC
CGACTTCAACCAGCCAGGACAGGCCTACGCGGTGATCGTGGGCGCTTCGATCGGACTCGGTCGCGTGATCGCACTCGACG
CCGAAGCCGCGCGCCGACTGCCAGGGGTACTGGCGGTACTGACGCACGAAAACGCGCCGAAACTGGCGTACGCCCCACAC
AAGGGCTTTATCGATCCGGAACACGGCGAACGTCTGCATGTCCTGCAGGACGATCACGTCCGCTTCTATGGCCAGCCGGT
TGCCGTGGTCGTGGCGCAGACGCTGGACCAGGCCGAGCATGCGGCCTGCCTGCTGCTGATTCGCTATGCCGAGGAATCAC
CGGTCTCCGACCCGCTCGACCAGCGCGCCGAAGCCGTGGTGCCGGAGGCGGGACGCGAACCAGGCCCCCATTCGGCGGAC
CGGGTCCGCGGCGACCCCGAGGCCGCGCTGGCGGCGGCTGCCGTCAGCATCGACGCCACCTACGATGCCGCGCGAGAAAA
TCACTTCCCGATCGAACCGAACGCCACCGTTGCCGCCTGGCAAGGCGACCAGCTGACGCTCTGGAGCAAGAGCCAGTTCG
TGATCAACGAGCAGGCCGAGATCGCGGCGATCCTCGGCATCCCGACTGAGAACGTCCACGTCATCTGCCCGTTTATCGGC
GGCGCCTTCGGCACCAGCCTGCGCACCTGGCCGCATGTCACGCTGGCGGCAGTCGCCGCGCGCGAAGTGGGCAAGCCCGT
CAAGCTGGTGCTGTCGCGGCGACAGATGTTCCATCAGACGGGGCACCGGCCGCGCACCGTGCAGCGCATTGCGCTGTCGG
CAACGCCCGACGGCAGGCTGACCGGCATCGTGCACGAAGGCACCGGCGAAACCAGCCGCCATGAGCAGTTCACCGAGGCA
CTCACTGCGGTGACGCCGTTCCTCTATCGCTGTCCCAATGTGCGCACTCGCTACCGGCTGGTGCCGCTGGACATCGGCAC
GCCGACCTTTATGCGGGGTCCGGGCGAGGCCACCGGCGTCTTTGCGCTGGAATGCGCGATGGACGAGCTGGCCTACGCCC
TCGAGATGGATCCGCTGGAACTGCGGCGGCGCAATGAACCCGGGCTCGACGAGGGCATGCAACTGCCGTTCTCCAGTCGC
TCCATGCTTGCCTGCTACGAACGCGGCGCCGACGCGTTCGGCTGGTCCCGCCGCACGCTCTCGCCCGGCTCGATGCGGGA
CGGCCGCCTGCATATCGGCTGGGGGATGGCCTGTGCCAGCTACCCGGTCTTCCACGGCCAGGCCAGCGCCCGCGTGCGCC
TGCTTGCCGACGGAACGGCCGAAGTCGAAGCCGCCGCCAGCGACATGGGGCCCGGCACCTACACCTCGATCACGCAGATT
GCCGCCGAGACGCTGGGCCTGCCGATGGACAGCGTGCGCTTCAGCCTTGGCCGTTCGGATTTCCCACCTACCCCGCCGCA
CGGGGGCTCGATGACCCTCGCGTCCGTCGGCTCGGCCGTGCGCGCGGCCTGCATTGCCGCGCTGGACCAGCGCCAGGCGC
GCGCGGATCGCACGGACGGCGCCATCGAAGCGAGCGCCACGGCAGGCCCGGATGGCGAGGTGCGCAGCCGGTTTTCCATG
CATGCCTTCGGTGCCGTGTTCGTCGAAGTCGCCATCGATCCCGATGTCGGCACGATCCGTGTCCGGCGCGTGGTCGGCGC
CTATGGCGCGGGTCGTATCGTGAATCCGCGGCTCGCAGCCAGCCAATGCACGGGCGGGATGGTCGGCGGCATCGGCATGG
CGCTGATGGAGCGAACCGCGCTGGATCCGCGGGACGGCCGGCCGGTGAATGCGCACATGGCGGATTACCTCGTGCCTGTC
AACCTGGATATCCACGGGCTGGAAGCGCATTTTGTCGACGAGGTCGATCCCCATGTGAACGAACTGGGCGTCAAGGGGTT
AGGTGAAATCGCGCTGGTGGGCGTGGCGCCGGCCGTGGCCAACGCCGTGTTTCACGCAACGGGAAAGCGCGTGCGGGAGC
TTCCGATCCGCATCGAGCACCTGGTCGAGCACTAG

Upstream 100 bases:

>100_bases
CCACGATTGCAGGCGCCACCCCGCTGCCAGGTAACCACTACAAGGTCGCGCTGCTGCAACGAACGGTGGTACGGGCCCTC
GAACTCGCAGGAGAAGGCAG

Downstream 100 bases:

>100_bases
TCCGGCAAGTGCGAGACATGCCGCCGACGCCGCCCAAACTGACGGCGTCGGCGGGGATCCGCAGGCTCGACGCGATTTTG
AAATGTATTTCTCTAAGGGC

Product: putative xanthine dehydrogenase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MNANHIGQPHARVDGRAKVTGSARYAADFNQPGQAYAVIVGASIGLGRVIALDAEAARRLPGVLAVLTHENAPKLAYAPH
KGFIDPEHGERLHVLQDDHVRFYGQPVAVVVAQTLDQAEHAACLLLIRYAEESPVSDPLDQRAEAVVPEAGREPGPHSAD
RVRGDPEAALAAAAVSIDATYDAARENHFPIEPNATVAAWQGDQLTLWSKSQFVINEQAEIAAILGIPTENVHVICPFIG
GAFGTSLRTWPHVTLAAVAAREVGKPVKLVLSRRQMFHQTGHRPRTVQRIALSATPDGRLTGIVHEGTGETSRHEQFTEA
LTAVTPFLYRCPNVRTRYRLVPLDIGTPTFMRGPGEATGVFALECAMDELAYALEMDPLELRRRNEPGLDEGMQLPFSSR
SMLACYERGADAFGWSRRTLSPGSMRDGRLHIGWGMACASYPVFHGQASARVRLLADGTAEVEAAASDMGPGTYTSITQI
AAETLGLPMDSVRFSLGRSDFPPTPPHGGSMTLASVGSAVRAACIAALDQRQARADRTDGAIEASATAGPDGEVRSRFSM
HAFGAVFVEVAIDPDVGTIRVRRVVGAYGAGRIVNPRLAASQCTGGMVGGIGMALMERTALDPRDGRPVNAHMADYLVPV
NLDIHGLEAHFVDEVDPHVNELGVKGLGEIALVGVAPAVANAVFHATGKRVRELPIRIEHLVEH

Sequences:

>Translated_704_residues
MNANHIGQPHARVDGRAKVTGSARYAADFNQPGQAYAVIVGASIGLGRVIALDAEAARRLPGVLAVLTHENAPKLAYAPH
KGFIDPEHGERLHVLQDDHVRFYGQPVAVVVAQTLDQAEHAACLLLIRYAEESPVSDPLDQRAEAVVPEAGREPGPHSAD
RVRGDPEAALAAAAVSIDATYDAARENHFPIEPNATVAAWQGDQLTLWSKSQFVINEQAEIAAILGIPTENVHVICPFIG
GAFGTSLRTWPHVTLAAVAAREVGKPVKLVLSRRQMFHQTGHRPRTVQRIALSATPDGRLTGIVHEGTGETSRHEQFTEA
LTAVTPFLYRCPNVRTRYRLVPLDIGTPTFMRGPGEATGVFALECAMDELAYALEMDPLELRRRNEPGLDEGMQLPFSSR
SMLACYERGADAFGWSRRTLSPGSMRDGRLHIGWGMACASYPVFHGQASARVRLLADGTAEVEAAASDMGPGTYTSITQI
AAETLGLPMDSVRFSLGRSDFPPTPPHGGSMTLASVGSAVRAACIAALDQRQARADRTDGAIEASATAGPDGEVRSRFSM
HAFGAVFVEVAIDPDVGTIRVRRVVGAYGAGRIVNPRLAASQCTGGMVGGIGMALMERTALDPRDGRPVNAHMADYLVPV
NLDIHGLEAHFVDEVDPHVNELGVKGLGEIALVGVAPAVANAVFHATGKRVRELPIRIEHLVEH
>Mature_704_residues
MNANHIGQPHARVDGRAKVTGSARYAADFNQPGQAYAVIVGASIGLGRVIALDAEAARRLPGVLAVLTHENAPKLAYAPH
KGFIDPEHGERLHVLQDDHVRFYGQPVAVVVAQTLDQAEHAACLLLIRYAEESPVSDPLDQRAEAVVPEAGREPGPHSAD
RVRGDPEAALAAAAVSIDATYDAARENHFPIEPNATVAAWQGDQLTLWSKSQFVINEQAEIAAILGIPTENVHVICPFIG
GAFGTSLRTWPHVTLAAVAAREVGKPVKLVLSRRQMFHQTGHRPRTVQRIALSATPDGRLTGIVHEGTGETSRHEQFTEA
LTAVTPFLYRCPNVRTRYRLVPLDIGTPTFMRGPGEATGVFALECAMDELAYALEMDPLELRRRNEPGLDEGMQLPFSSR
SMLACYERGADAFGWSRRTLSPGSMRDGRLHIGWGMACASYPVFHGQASARVRLLADGTAEVEAAASDMGPGTYTSITQI
AAETLGLPMDSVRFSLGRSDFPPTPPHGGSMTLASVGSAVRAACIAALDQRQARADRTDGAIEASATAGPDGEVRSRFSM
HAFGAVFVEVAIDPDVGTIRVRRVVGAYGAGRIVNPRLAASQCTGGMVGGIGMALMERTALDPRDGRPVNAHMADYLVPV
NLDIHGLEAHFVDEVDPHVNELGVKGLGEIALVGVAPAVANAVFHATGKRVRELPIRIEHLVEH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=674, Percent_Identity=23.7388724035608, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI71773480, Length=666, Percent_Identity=22.972972972973, Blast_Score=123, Evalue=5e-28,
Organism=Escherichia coli, GI1786478, Length=733, Percent_Identity=38.4720327421555, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789230, Length=752, Percent_Identity=30.8510638297872, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1789246, Length=792, Percent_Identity=25.8838383838384, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32566215, Length=514, Percent_Identity=22.1789883268482, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=679, Percent_Identity=21.6494845360825, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647199, Length=668, Percent_Identity=24.1017964071856, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24647201, Length=664, Percent_Identity=25, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24647193, Length=664, Percent_Identity=25.6024096385542, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24647195, Length=677, Percent_Identity=24.0768094534712, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24647197, Length=668, Percent_Identity=24.1017964071856, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI17737937, Length=666, Percent_Identity=25.0750750750751, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 75288; Mature: 75288

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANHIGQPHARVDGRAKVTGSARYAADFNQPGQAYAVIVGASIGLGRVIALDAEAARRL
CCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCEEEEEEECCCCCCEEEEECHHHHHCC
PGVLAVLTHENAPKLAYAPHKGFIDPEHGERLHVLQDDHVRFYGQPVAVVVAQTLDQAEH
CCEEEEEECCCCCCEEECCCCCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
AACLLLIRYAEESPVSDPLDQRAEAVVPEAGREPGPHSADRVRGDPEAALAAAAVSIDAT
HEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHEEEEECC
YDAARENHFPIEPNATVAAWQGDQLTLWSKSQFVINEQAEIAAILGIPTENVHVICPFIG
HHHHCCCCCCCCCCCEEEEECCCEEEEEECCEEEECCCCEEEEEEECCCCCCEEEEECCC
GAFGTSLRTWPHVTLAAVAAREVGKPVKLVLSRRQMFHQTGHRPRTVQRIALSATPDGRL
CHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCE
TGIVHEGTGETSRHEQFTEALTAVTPFLYRCPNVRTRYRLVPLDIGTPTFMRGPGEATGV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCE
FALECAMDELAYALEMDPLELRRRNEPGLDEGMQLPFSSRSMLACYERGADAFGWSRRTL
EEEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
SPGSMRDGRLHIGWGMACASYPVFHGQASARVRLLADGTAEVEAAASDMGPGTYTSITQI
CCCCCCCCEEEEEECHHHHCCCEECCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHH
AAETLGLPMDSVRFSLGRSDFPPTPPHGGSMTLASVGSAVRAACIAALDQRQARADRTDG
HHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AIEASATAGPDGEVRSRFSMHAFGAVFVEVAIDPDVGTIRVRRVVGAYGAGRIVNPRLAA
CEEECCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCEEEHHHHHCCCCCCCCCCCHHH
SQCTGGMVGGIGMALMERTALDPRDGRPVNAHMADYLVPVNLDIHGLEAHFVDEVDPHVN
HHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCEEECCCHHCCCCCCCCHH
ELGVKGLGEIALVGVAPAVANAVFHATGKRVRELPIRIEHLVEH
HHCCCCCCCEEEEECHHHHHHHHHHHCCHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MNANHIGQPHARVDGRAKVTGSARYAADFNQPGQAYAVIVGASIGLGRVIALDAEAARRL
CCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCEEEEEEECCCCCCEEEEECHHHHHCC
PGVLAVLTHENAPKLAYAPHKGFIDPEHGERLHVLQDDHVRFYGQPVAVVVAQTLDQAEH
CCEEEEEECCCCCCEEECCCCCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
AACLLLIRYAEESPVSDPLDQRAEAVVPEAGREPGPHSADRVRGDPEAALAAAAVSIDAT
HEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHEEEEECC
YDAARENHFPIEPNATVAAWQGDQLTLWSKSQFVINEQAEIAAILGIPTENVHVICPFIG
HHHHCCCCCCCCCCCEEEEECCCEEEEEECCEEEECCCCEEEEEEECCCCCCEEEEECCC
GAFGTSLRTWPHVTLAAVAAREVGKPVKLVLSRRQMFHQTGHRPRTVQRIALSATPDGRL
CHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCE
TGIVHEGTGETSRHEQFTEALTAVTPFLYRCPNVRTRYRLVPLDIGTPTFMRGPGEATGV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCE
FALECAMDELAYALEMDPLELRRRNEPGLDEGMQLPFSSRSMLACYERGADAFGWSRRTL
EEEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
SPGSMRDGRLHIGWGMACASYPVFHGQASARVRLLADGTAEVEAAASDMGPGTYTSITQI
CCCCCCCCEEEEEECHHHHCCCEECCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHH
AAETLGLPMDSVRFSLGRSDFPPTPPHGGSMTLASVGSAVRAACIAALDQRQARADRTDG
HHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AIEASATAGPDGEVRSRFSMHAFGAVFVEVAIDPDVGTIRVRRVVGAYGAGRIVNPRLAA
CEEECCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCEEEHHHHHCCCCCCCCCCCHHH
SQCTGGMVGGIGMALMERTALDPRDGRPVNAHMADYLVPVNLDIHGLEAHFVDEVDPHVN
HHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCEEECCCHHCCCCCCCCHH
ELGVKGLGEIALVGVAPAVANAVFHATGKRVRELPIRIEHLVEH
HHCCCCCCCEEEEECHHHHHHHHHHHCCHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]