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The map label for this gene is xsc [H]

Identifier: 116695806

GI number: 116695806

Start: 2115288

End: 2117144

Strand: Direct

Name: xsc [H]

Synonym: H16_B1870

Alternate gene names: 116695806

Gene position: 2115288-2117144 (Clockwise)

Preceding gene: 116695805

Following gene: 116695807

Centisome position: 72.63

GC content: 67.21

Gene sequence:

>1857_bases
ATGCGCGACCTCGATACCACCTCGAATCCCGCCGTTTCCGGTGGCTCGGCCGCCGCGAAGGAGAGCCAGGTCCCGGCCGG
CCCGCAGACCATGACCCCGTCGGAAGCCTTCGTTGAAACGCTGGCCGCCAATGGCGTGACCGACATGTTCGGCATCATGG
GCTCGGCCTTCATGGATGCGATGGACATCTTCGCGCCGGCGGGCATCCGCCTGATCCCGGTGGTGCACGAACAAGGCGCC
GGCCACATGGCCGACGGCTACGCCCGCGTGTCGGGCCGCCACGGTGTGGTGATCGGCCAGAACGGCCCCGGCATCTCCAA
CTGCGTGACCTCGATCGCCGCTGCCTACTGGGCCCACAGCCCGGTGGTGATCGTCACGCCCGAGGCCGGCACCATGGGCA
TTGGCCTGGGCGGCTTCCAGGAAGCCAACCAGCTGCCCATGTTCCAGGAGTTCACCAAGTACCAGGGCCACGTCACCAAC
CCGGCCCGCATGGCCGAGTTCACCGCCCGCTGCTTCGACCGCGCCACCGCGGAAATGGGCCCGACCCAGCTGAACATCCC
GCGTGACCACTTCTACGGCAAGGTCAACGTCGAGATCCCGCAGCCGCGCCGCCTCGACCGCGGCCCCGGCGGCGAGCAGA
GCCTGAACGAAGCGGCCGAGCTGCTGGCCAACGCCAAATTCCCGGTGATCATCTCGGGCGGCGGCGTGGTGATGGCCGAT
GCGATCGAAGAGTGCAAGGCCCTGGCCGAGCGCCTGGGCGCGCCGGTGGTCAACAGCTACCTGCACAACGACTCGTTCCC
GGCCAGCCACCCGCTGTGGTGCGGCCCGCTGGGCTACCAGGGTTCGAAGGCGGCGATGAAGCTGATCTCGCGCGCCGACG
TGGTGATCGCGCTGGGCTCGCGCCTGGGGCCGTTCGGCACGCTGCCGCAGCACGGCATGGACTACTGGCCGAAGAACGCC
AAGATCATCCAGATCGACGCCGACCACAAGATGCTGGGCCTGGTGAAGAAGATCTCGGTGGGCATCTGCGGCGACGCCAA
GGCCGCCGCGGTCGCGCTGAGCCAGCGCCTGGCCGGCCGCACGCTGGCCTGCGACGCCAGCCGCGAGGCCCGCGCCACCG
AAATCGCCAACGAAAAGGCCGCGTGGGAGAAGGAGCTGGACGACTGGACCCATGAGCGCGACCCGTACAGCCTGGACATG
ATCGAAGAGCAGAAGCAGGAGCGCACGCCCACCGGCGGCCACTACCTGCATCCGCGCCAGGTGCTGCGCGAGCTGGAAAA
GGCCATGCCGGAAGATGTGATGGTGTCCACCGACATCGGCAACATCAACTCGGTGGCCAACAGCTACCTGCGCTTCGAGA
AGCCGCGCAGCTTCTTCGCGGCGATGAGCTGGGGCAACTGCGGTTACGCCTTCCCGACCATCATCGGCGCCAAGGTCGCG
GCACCGCACCGCCCGGCCGTGTCGTACGCCGGTGACGGCGCCTGGGGCATGAGCCTGATGGAAACCATGACCTGCGTGCG
CCACAACATCCCGGTGACCGCGGTGGTGTTCCACAACCGCCAGTGGGGCGCGGAGAAGAAGAACCAGGTGGACTTCTACA
ACCGCCGCTTTGTGGCGGGCGAGCTGGACAACCAGAGCTTTGCCGGCATCGCCAAGGCGATGGGTGCGGAAGGCATCGTG
GTGGATCGGCTGGAAGATGTCGGCCCGGCCCTGAAGCGCGCCATCGACCTGCAGATGAATCATGGCAAGACCACGATCAT
CGAGATCATGTGCACGCGTGAACTGGGCGACCCGTTCCGCCGCGATGCGCTGGCCAAGCCGGTGCGTTACCTGGACAAGT
ACAAGGACTACGTCTGA

Upstream 100 bases:

>100_bases
CTATTGACCAACCGAAGTCTTCCGCCTACATTTCCTCCAGCAAGCAATTTTCCGGAACGTCCTGTTCCACTTTATAAGAC
CCTCATCAGGAGACAACGCC

Downstream 100 bases:

>100_bases
TCGAAGTACTGCACACCGCCAGCTGACGGCGTGCTCCCTCTCCCGCTTGCGGGAGAGGGGAGAACACCAAGGGCATAGCG
CAGGTCGCTGGCCCTTTTTT

Product: sulfoacetaldehyde acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MRDLDTTSNPAVSGGSAAAKESQVPAGPQTMTPSEAFVETLAANGVTDMFGIMGSAFMDAMDIFAPAGIRLIPVVHEQGA
GHMADGYARVSGRHGVVIGQNGPGISNCVTSIAAAYWAHSPVVIVTPEAGTMGIGLGGFQEANQLPMFQEFTKYQGHVTN
PARMAEFTARCFDRATAEMGPTQLNIPRDHFYGKVNVEIPQPRRLDRGPGGEQSLNEAAELLANAKFPVIISGGGVVMAD
AIEECKALAERLGAPVVNSYLHNDSFPASHPLWCGPLGYQGSKAAMKLISRADVVIALGSRLGPFGTLPQHGMDYWPKNA
KIIQIDADHKMLGLVKKISVGICGDAKAAAVALSQRLAGRTLACDASREARATEIANEKAAWEKELDDWTHERDPYSLDM
IEEQKQERTPTGGHYLHPRQVLRELEKAMPEDVMVSTDIGNINSVANSYLRFEKPRSFFAAMSWGNCGYAFPTIIGAKVA
APHRPAVSYAGDGAWGMSLMETMTCVRHNIPVTAVVFHNRQWGAEKKNQVDFYNRRFVAGELDNQSFAGIAKAMGAEGIV
VDRLEDVGPALKRAIDLQMNHGKTTIIEIMCTRELGDPFRRDALAKPVRYLDKYKDYV

Sequences:

>Translated_618_residues
MRDLDTTSNPAVSGGSAAAKESQVPAGPQTMTPSEAFVETLAANGVTDMFGIMGSAFMDAMDIFAPAGIRLIPVVHEQGA
GHMADGYARVSGRHGVVIGQNGPGISNCVTSIAAAYWAHSPVVIVTPEAGTMGIGLGGFQEANQLPMFQEFTKYQGHVTN
PARMAEFTARCFDRATAEMGPTQLNIPRDHFYGKVNVEIPQPRRLDRGPGGEQSLNEAAELLANAKFPVIISGGGVVMAD
AIEECKALAERLGAPVVNSYLHNDSFPASHPLWCGPLGYQGSKAAMKLISRADVVIALGSRLGPFGTLPQHGMDYWPKNA
KIIQIDADHKMLGLVKKISVGICGDAKAAAVALSQRLAGRTLACDASREARATEIANEKAAWEKELDDWTHERDPYSLDM
IEEQKQERTPTGGHYLHPRQVLRELEKAMPEDVMVSTDIGNINSVANSYLRFEKPRSFFAAMSWGNCGYAFPTIIGAKVA
APHRPAVSYAGDGAWGMSLMETMTCVRHNIPVTAVVFHNRQWGAEKKNQVDFYNRRFVAGELDNQSFAGIAKAMGAEGIV
VDRLEDVGPALKRAIDLQMNHGKTTIIEIMCTRELGDPFRRDALAKPVRYLDKYKDYV
>Mature_618_residues
MRDLDTTSNPAVSGGSAAAKESQVPAGPQTMTPSEAFVETLAANGVTDMFGIMGSAFMDAMDIFAPAGIRLIPVVHEQGA
GHMADGYARVSGRHGVVIGQNGPGISNCVTSIAAAYWAHSPVVIVTPEAGTMGIGLGGFQEANQLPMFQEFTKYQGHVTN
PARMAEFTARCFDRATAEMGPTQLNIPRDHFYGKVNVEIPQPRRLDRGPGGEQSLNEAAELLANAKFPVIISGGGVVMAD
AIEECKALAERLGAPVVNSYLHNDSFPASHPLWCGPLGYQGSKAAMKLISRADVVIALGSRLGPFGTLPQHGMDYWPKNA
KIIQIDADHKMLGLVKKISVGICGDAKAAAVALSQRLAGRTLACDASREARATEIANEKAAWEKELDDWTHERDPYSLDM
IEEQKQERTPTGGHYLHPRQVLRELEKAMPEDVMVSTDIGNINSVANSYLRFEKPRSFFAAMSWGNCGYAFPTIIGAKVA
APHRPAVSYAGDGAWGMSLMETMTCVRHNIPVTAVVFHNRQWGAEKKNQVDFYNRRFVAGELDNQSFAGIAKAMGAEGIV
VDRLEDVGPALKRAIDLQMNHGKTTIIEIMCTRELGDPFRRDALAKPVRYLDKYKDYV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21361361, Length=607, Percent_Identity=24.5469522240527, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI93004078, Length=585, Percent_Identity=22.7350427350427, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI87081685, Length=570, Percent_Identity=26.6666666666667, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1790104, Length=555, Percent_Identity=25.9459459459459, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786717, Length=585, Percent_Identity=24.7863247863248, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787096, Length=587, Percent_Identity=24.5315161839864, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1788716, Length=500, Percent_Identity=24.6, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17542570, Length=586, Percent_Identity=23.5494880546075, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17531299, Length=589, Percent_Identity=24.1086587436333, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17531301, Length=589, Percent_Identity=24.1086587436333, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323755, Length=568, Percent_Identity=27.4647887323944, Blast_Score=196, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6320816, Length=592, Percent_Identity=21.7905405405405, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19922626, Length=576, Percent_Identity=24.1319444444444, Blast_Score=120, Evalue=4e-27,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017820
- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =2.3.3.15 [H]

Molecular weight: Translated: 66959; Mature: 66959

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLDTTSNPAVSGGSAAAKESQVPAGPQTMTPSEAFVETLAANGVTDMFGIMGSAFMDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MDIFAPAGIRLIPVVHEQGAGHMADGYARVSGRHGVVIGQNGPGISNCVTSIAAAYWAHS
HHHHCCCCCEEEEEEECCCCCCCCCCHHEECCCCCEEECCCCCCHHHHHHHHHHHHHCCC
PVVIVTPEAGTMGIGLGGFQEANQLPMFQEFTKYQGHVTNPARMAEFTARCFDRATAEMG
CEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PTQLNIPRDHFYGKVNVEIPQPRRLDRGPGGEQSLNEAAELLANAKFPVIISGGGVVMAD
CCEECCCHHHCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEHH
AIEECKALAERLGAPVVNSYLHNDSFPASHPLWCGPLGYQGSKAAMKLISRADVVIALGS
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCEEEEECC
RLGPFGTLPQHGMDYWPKNAKIIQIDADHKMLGLVKKISVGICGDAKAAAVALSQRLAGR
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
TLACDASREARATEIANEKAAWEKELDDWTHERDPYSLDMIEEQKQERTPTGGHYLHPRQ
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECHHH
VLRELEKAMPEDVMVSTDIGNINSVANSYLRFEKPRSFFAAMSWGNCGYAFPTIIGAKVA
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCC
APHRPAVSYAGDGAWGMSLMETMTCVRHNIPVTAVVFHNRQWGAEKKNQVDFYNRRFVAG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHCEEEEE
ELDNQSFAGIAKAMGAEGIVVDRLEDVGPALKRAIDLQMNHGKTTIIEIMCTRELGDPFR
CCCCCHHHHHHHHHCCCCEEEHHHHHHCHHHHHHHHEEECCCCEEEEEEEECHHHCCHHH
RDALAKPVRYLDKYKDYV
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDLDTTSNPAVSGGSAAAKESQVPAGPQTMTPSEAFVETLAANGVTDMFGIMGSAFMDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MDIFAPAGIRLIPVVHEQGAGHMADGYARVSGRHGVVIGQNGPGISNCVTSIAAAYWAHS
HHHHCCCCCEEEEEEECCCCCCCCCCHHEECCCCCEEECCCCCCHHHHHHHHHHHHHCCC
PVVIVTPEAGTMGIGLGGFQEANQLPMFQEFTKYQGHVTNPARMAEFTARCFDRATAEMG
CEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PTQLNIPRDHFYGKVNVEIPQPRRLDRGPGGEQSLNEAAELLANAKFPVIISGGGVVMAD
CCEECCCHHHCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEHH
AIEECKALAERLGAPVVNSYLHNDSFPASHPLWCGPLGYQGSKAAMKLISRADVVIALGS
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCEEEEECC
RLGPFGTLPQHGMDYWPKNAKIIQIDADHKMLGLVKKISVGICGDAKAAAVALSQRLAGR
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
TLACDASREARATEIANEKAAWEKELDDWTHERDPYSLDMIEEQKQERTPTGGHYLHPRQ
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECHHH
VLRELEKAMPEDVMVSTDIGNINSVANSYLRFEKPRSFFAAMSWGNCGYAFPTIIGAKVA
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCC
APHRPAVSYAGDGAWGMSLMETMTCVRHNIPVTAVVFHNRQWGAEKKNQVDFYNRRFVAG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHCEEEEE
ELDNQSFAGIAKAMGAEGIVVDRLEDVGPALKRAIDLQMNHGKTTIIEIMCTRELGDPFR
CCCCCHHHHHHHHHCCCCEEEHHHHHHCHHHHHHHHEEECCCCEEEEEEEECHHHCCHHH
RDALAKPVRYLDKYKDYV
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12358600 [H]