| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is ykvO [H]
Identifier: 116695668
GI number: 116695668
Start: 1967505
End: 1968266
Strand: Direct
Name: ykvO [H]
Synonym: H16_B1732
Alternate gene names: 116695668
Gene position: 1967505-1968266 (Clockwise)
Preceding gene: 116695666
Following gene: 116695682
Centisome position: 67.55
GC content: 59.45
Gene sequence:
>762_bases ATGAGTAATTCCCTTGAAGGAAAAGTCGCCGTGATCACGGGCGGCACAACAGGAATCGGTCTGGCAATCGCCAAGGAATT CGTTGCGGAAGGCGCTAAAGTTGTTGTGACGGCGCTTCAACAGGAGGCACTCGACGAAGCCGTCAGGGAAATCGGCCCGC GCAGCTTCGGTGCCAAGGCGGATGCTTCCAGCATTGCCGAGATGGACGCGCTGCTGAAGCGAGTCAAAGCCGATCACGGG AGATTGGATGCCGTCATCGCCAACGCCGTCGCTGACGAGCATGCGCCGCTGGGCAAGATTACAGAAGAACAGTTCGACAA GATGGTCGGCGTCAATCTCAAGGGCGTGCTCTTCACCATCCAGTCTGCGATGCCGCTGCTGGAGAGCGACGGCAGCATCA TTCTTATCGGGTCGACCGCTTCAGTCGCCCCACCCGCTGGCATGAGCATCTATGGCGCGATCAAAGCCGCATTCCACGGC ATGGTCCGGTCCCTGATCCAGGATGCCAAAGACACCGGCGTCCGGATCAACATTCTGAGCCCGGGGGCAGTAGACACGCC TTCCCTGCGCAGAGCGCTTATCAAAGCGGCAGGCGCCGACATGGCGGACGCCATCGTTCAATCCATCGCGCAACGAAGCC CAGCGGGCCGCATCGGTGATGCTCGCGAAATCGGCAAGGTCGCGGTTTTCCTCGCCAGCGATGCATCAAGCTATGTGAAC GGCGTCGAGTTGTTTGTCGACGGCGGATTGAGACAAGTTTGA
Upstream 100 bases:
>100_bases ACGCTCTCGCAGGTTTTATAGAATCCCAAGCATTCCATGCACAGCTCGATGGAAGTATCTTTCTGCAAGAGGACGTTTAA TCAATCCAATTGGAGATGAC
Downstream 100 bases:
>100_bases GGCTTCCGCGCTAAGCACGGGGACCCCGCCCGCTGCCTGATCGCTACCGGCTTGCCTTCGCGAAGAGGCACCGGTAGCGC CCGGGGGCCATGCCTGAGGA
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MSNSLEGKVAVITGGTTGIGLAIAKEFVAEGAKVVVTALQQEALDEAVREIGPRSFGAKADASSIAEMDALLKRVKADHG RLDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFTIQSAMPLLESDGSIILIGSTASVAPPAGMSIYGAIKAAFHG MVRSLIQDAKDTGVRINILSPGAVDTPSLRRALIKAAGADMADAIVQSIAQRSPAGRIGDAREIGKVAVFLASDASSYVN GVELFVDGGLRQV
Sequences:
>Translated_253_residues MSNSLEGKVAVITGGTTGIGLAIAKEFVAEGAKVVVTALQQEALDEAVREIGPRSFGAKADASSIAEMDALLKRVKADHG RLDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFTIQSAMPLLESDGSIILIGSTASVAPPAGMSIYGAIKAAFHG MVRSLIQDAKDTGVRINILSPGAVDTPSLRRALIKAAGADMADAIVQSIAQRSPAGRIGDAREIGKVAVFLASDASSYVN GVELFVDGGLRQV >Mature_252_residues SNSLEGKVAVITGGTTGIGLAIAKEFVAEGAKVVVTALQQEALDEAVREIGPRSFGAKADASSIAEMDALLKRVKADHGR LDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFTIQSAMPLLESDGSIILIGSTASVAPPAGMSIYGAIKAAFHGM VRSLIQDAKDTGVRINILSPGAVDTPSLRRALIKAAGADMADAIVQSIAQRSPAGRIGDAREIGKVAVFLASDASSYVNG VELFVDGGLRQV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=3e-24, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=28.4584980237154, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=32.1285140562249, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=28.125, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=26.8, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=32.034632034632, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=26.5060240963855, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=26.8482490272374, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=28.1914893617021, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=28.515625, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=29.2817679558011, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI83715985, Length=266, Percent_Identity=27.8195488721804, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=25.9842519685039, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=30.952380952381, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=30.8, Blast_Score=121, Evalue=3e-29, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.968253968254, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=31.3953488372093, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=31.496062992126, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787820, Length=236, Percent_Identity=30.5084745762712, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.46875, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=27.2373540856031, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=27.4900398406374, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=26.6932270916335, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.0395256916996, Blast_Score=113, Evalue=9e-26, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=33.7121212121212, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=32.1969696969697, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=30.6201550387597, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=27.1653543307087, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.9391634980989, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=32.6848249027237, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.8973384030418, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=32.6923076923077, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.1787072243346, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=30.6818181818182, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=29.6577946768061, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=30.2325581395349, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=26.8482490272374, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=31.8352059925094, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=26.7206477732794, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=30.2325581395349, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=30.8270676691729, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17567345, Length=218, Percent_Identity=27.5229357798165, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.4776119402985, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=24.7148288973384, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.4, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.6119402985075, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=28.735632183908, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17564282, Length=226, Percent_Identity=27.4336283185841, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI32563809, Length=251, Percent_Identity=24.7011952191235, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17507613, Length=251, Percent_Identity=24.7011952191235, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=31.6062176165803, Blast_Score=93, Evalue=5e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6320089, Length=187, Percent_Identity=29.9465240641711, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.0158102766798, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=29.7619047619048, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.241935483871, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=27.3809523809524, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=27.1653543307087, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=27.4900398406374, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=29.8039215686275, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI24640492, Length=213, Percent_Identity=26.2910798122066, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=26.5151515151515, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI116007236, Length=218, Percent_Identity=29.3577981651376, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=29.296875, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI21355631, Length=165, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26047; Mature: 25916
Theoretical pI: Translated: 5.37; Mature: 5.37
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNSLEGKVAVITGGTTGIGLAIAKEFVAEGAKVVVTALQQEALDEAVREIGPRSFGAKA CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC DASSIAEMDALLKRVKADHGRLDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFTI CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHH QSAMPLLESDGSIILIGSTASVAPPAGMSIYGAIKAAFHGMVRSLIQDAKDTGVRINILS HHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC PGAVDTPSLRRALIKAAGADMADAIVQSIAQRSPAGRIGDAREIGKVAVFLASDASSYVN CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEECCHHHHHC GVELFVDGGLRQV HHHEEECCCCCCC >Mature Secondary Structure SNSLEGKVAVITGGTTGIGLAIAKEFVAEGAKVVVTALQQEALDEAVREIGPRSFGAKA CCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC DASSIAEMDALLKRVKADHGRLDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFTI CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHH QSAMPLLESDGSIILIGSTASVAPPAGMSIYGAIKAAFHGMVRSLIQDAKDTGVRINILS HHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC PGAVDTPSLRRALIKAAGADMADAIVQSIAQRSPAGRIGDAREIGKVAVFLASDASSYVN CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEECCHHHHHC GVELFVDGGLRQV HHHEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]