Click here to switch to the map view.

The map label for this gene is fabB [H]

Identifier: 116695606

GI number: 116695606

Start: 1878208

End: 1879410

Strand: Direct

Name: fabB [H]

Synonym: H16_B1667

Alternate gene names: 116695606

Gene position: 1878208-1879410 (Clockwise)

Preceding gene: 116695605

Following gene: 116695607

Centisome position: 64.49

GC content: 70.91

Gene sequence:

>1203_bases
GTGTCCCCGCTCCTGTTCTCGCATTTCACGGCCACCAGCTGCCTTGGCGCCGGTGTAGACGCCACCCTGTCGGCACTGCG
TGCGCAGCGCGGCGGCCTGGCGCCCTGCCGCTTCGGCGGTGTCGAGCTCGATACCTTCGTCGGCGAAGTCCCCGGCCTGG
ACACCGTGGCACTGCCGCCCGCACTGGCCGAATTCGACTGCCGCAACAACCGGCTGGCGCAACTGGCGCTGGAGCAGGAC
GGCTTTGCCGCGCGCGTGCGCGAAGCGGCGGCGCGCTACGGCGCCCACCGGGTCGGCGTCTTCCTGGGCACCAGCACCGC
GGGCGTGCTGCAGACGGAACTGGCCTATCGCCAGCGCGATCCTGCCAGCGGCGCGCTGCCGCCGGGCTTCCATTACGCCA
CCACCCACAACCCCTACTCGCTGCCCGCCTTCCTGCGCCAATACCTGGGACTGACCGGTCCCGCGGCTGCGGTGTCCTCG
GCCTGTTCATCCGGCGCCAAGGTGTTCAGTTCGGCACGGCGCATGCTGGAGGCAGGGCTGATCGATGTGGCTGTGGTCGG
CGGCGTCGATTCGCTGTGCCACACCACGCTGTACGGCTTCAATTCGCTGGAGCTGTTGTCCGACCAGCCGTGCCGGCCCT
ATGACGTGGCGCGCAACGGCATCTCGATCGGCGAGGGCGCGGCATTCGGCCTGCTCGAGCGCGTGGCCGGCAGCGCGCAA
GGCGATGCCATCCTGCTGGCCGGGATCGGCGAATCCAGCGATGCGCACCATATGTCGACCCCGCACCCCGACGGGCTGGG
CGCGCGCCTGGCACTAGAGCAGGCACTGGCCAGCGCGGGGGTCGCGCCGGCGCAGGTCGGCTACGTCAACCTGCATGGCA
CCGCCACGCGCAGCAACGACGCGGCCGAGGCCATGGCCATGGCCGCGGTGCTGCCCGGCACGCCGTGCAGCTCAACCAAG
GGCGCCACCGGGCATGCGCTGGGTGCCGCCGGCGCGCTCGAAGCCGTCATTTGCGCGCTGGCGCTGCGCCACGGCCTGAT
GCCCGGCGGCATCAACACCACGCAGGTGGATCCGGCGCTGGACGTGAACTACCAGCTCGCCAACCGCGAGGCACCGCTGC
GCTATGCGATGACCAATGCCTTCGGCTTCGGCGGATCCAACTGCAGCCTGCTGTTCGCCCGCGCGGACGCGGCTTCCCAC
TGA

Upstream 100 bases:

>100_bases
CGTCACGCTGCGCGCGGCCGTGCCGACAGCCTGAGTGAGCGGCGGCTTGTTACAATTGGCACAGCCTTCCGAGATTCCTT
CCATTCGTTCCCCCTAAGCC

Downstream 100 bases:

>100_bases
GCATCGCCATGCCGCAGCACGTGTATATCGAAAGCATCGGCCTGCTCGGCCCCGGCCTGACCGGCTGGCAGCAGGCCGCC
GAAGTCCTTGCCGGCCGCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSPLLFSHFTATSCLGAGVDATLSALRAQRGGLAPCRFGGVELDTFVGEVPGLDTVALPPALAEFDCRNNRLAQLALEQD
GFAARVREAAARYGAHRVGVFLGTSTAGVLQTELAYRQRDPASGALPPGFHYATTHNPYSLPAFLRQYLGLTGPAAAVSS
ACSSGAKVFSSARRMLEAGLIDVAVVGGVDSLCHTTLYGFNSLELLSDQPCRPYDVARNGISIGEGAAFGLLERVAGSAQ
GDAILLAGIGESSDAHHMSTPHPDGLGARLALEQALASAGVAPAQVGYVNLHGTATRSNDAAEAMAMAAVLPGTPCSSTK
GATGHALGAAGALEAVICALALRHGLMPGGINTTQVDPALDVNYQLANREAPLRYAMTNAFGFGGSNCSLLFARADAASH

Sequences:

>Translated_400_residues
MSPLLFSHFTATSCLGAGVDATLSALRAQRGGLAPCRFGGVELDTFVGEVPGLDTVALPPALAEFDCRNNRLAQLALEQD
GFAARVREAAARYGAHRVGVFLGTSTAGVLQTELAYRQRDPASGALPPGFHYATTHNPYSLPAFLRQYLGLTGPAAAVSS
ACSSGAKVFSSARRMLEAGLIDVAVVGGVDSLCHTTLYGFNSLELLSDQPCRPYDVARNGISIGEGAAFGLLERVAGSAQ
GDAILLAGIGESSDAHHMSTPHPDGLGARLALEQALASAGVAPAQVGYVNLHGTATRSNDAAEAMAMAAVLPGTPCSSTK
GATGHALGAAGALEAVICALALRHGLMPGGINTTQVDPALDVNYQLANREAPLRYAMTNAFGFGGSNCSLLFARADAASH
>Mature_399_residues
SPLLFSHFTATSCLGAGVDATLSALRAQRGGLAPCRFGGVELDTFVGEVPGLDTVALPPALAEFDCRNNRLAQLALEQDG
FAARVREAAARYGAHRVGVFLGTSTAGVLQTELAYRQRDPASGALPPGFHYATTHNPYSLPAFLRQYLGLTGPAAAVSSA
CSSGAKVFSSARRMLEAGLIDVAVVGGVDSLCHTTLYGFNSLELLSDQPCRPYDVARNGISIGEGAAFGLLERVAGSAQG
DAILLAGIGESSDAHHMSTPHPDGLGARLALEQALASAGVAPAQVGYVNLHGTATRSNDAAEAMAMAAVLPGTPCSSTKG
ATGHALGAAGALEAVICALALRHGLMPGGINTTQVDPALDVNYQLANREAPLRYAMTNAFGFGGSNCSLLFARADAASH

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=260, Percent_Identity=39.2307692307692, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=40.5405405405405, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI41872631, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1787337, Length=261, Percent_Identity=38.6973180076628, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788663, Length=259, Percent_Identity=30.8880308880309, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71983541, Length=413, Percent_Identity=29.2978208232446, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=33.8461538461538, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI212642053, Length=320, Percent_Identity=27.8125, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=317, Percent_Identity=23.3438485804416, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320904, Length=292, Percent_Identity=34.5890410958904, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24644341, Length=322, Percent_Identity=36.0248447204969, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI221330659, Length=310, Percent_Identity=25.4838709677419, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920632, Length=310, Percent_Identity=25.4838709677419, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24581345, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 40904; Mature: 40772

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLLFSHFTATSCLGAGVDATLSALRAQRGGLAPCRFGGVELDTFVGEVPGLDTVALPP
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCC
ALAEFDCRNNRLAQLALEQDGFAARVREAAARYGAHRVGVFLGTSTAGVLQTELAYRQRD
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCC
PASGALPPGFHYATTHNPYSLPAFLRQYLGLTGPAAAVSSACSSGAKVFSSARRMLEAGL
CCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDVAVVGGVDSLCHTTLYGFNSLELLSDQPCRPYDVARNGISIGEGAAFGLLERVAGSAQ
CEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCC
GDAILLAGIGESSDAHHMSTPHPDGLGARLALEQALASAGVAPAQVGYVNLHGTATRSND
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCH
AAEAMAMAAVLPGTPCSSTKGATGHALGAAGALEAVICALALRHGLMPGGINTTQVDPAL
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DVNYQLANREAPLRYAMTNAFGFGGSNCSLLFARADAASH
CCCEEECCCCCCEEEEHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SPLLFSHFTATSCLGAGVDATLSALRAQRGGLAPCRFGGVELDTFVGEVPGLDTVALPP
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCC
ALAEFDCRNNRLAQLALEQDGFAARVREAAARYGAHRVGVFLGTSTAGVLQTELAYRQRD
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCC
PASGALPPGFHYATTHNPYSLPAFLRQYLGLTGPAAAVSSACSSGAKVFSSARRMLEAGL
CCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDVAVVGGVDSLCHTTLYGFNSLELLSDQPCRPYDVARNGISIGEGAAFGLLERVAGSAQ
CEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCC
GDAILLAGIGESSDAHHMSTPHPDGLGARLALEQALASAGVAPAQVGYVNLHGTATRSND
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCH
AAEAMAMAAVLPGTPCSSTKGATGHALGAAGALEAVICALALRHGLMPGGINTTQVDPAL
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DVNYQLANREAPLRYAMTNAFGFGGSNCSLLFARADAASH
CCCEEECCCCCCEEEEHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]