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The map label for this gene is ccpA [H]

Identifier: 116695538

GI number: 116695538

Start: 1802631

End: 1803728

Strand: Direct

Name: ccpA [H]

Synonym: H16_B1599

Alternate gene names: 116695538

Gene position: 1802631-1803728 (Clockwise)

Preceding gene: 116695531

Following gene: 116695539

Centisome position: 61.89

GC content: 69.58

Gene sequence:

>1098_bases
ATGAAAACGTTTTCATCCGGAGCTCTAAGCGTGAATCGCAAAGATCCAGCGGGGGGCAGGCCCGACACGACAGGTGGCGC
CACCCTGATCGACGTGGCGCAAGCCGCGCGGGTGTCGCTCGCCACCGCATCGCGCGTGTTCAGCAGCCCGCACCTGGTGC
GCGACAGCACGGCGCAGCGCGTGCGCGAGGCGGCGCGCCGGCTCAGCTTTCGCCCCAACCTGCTCGGCAGCAAGCTGCGC
GCCCAGCAGACCCGCATGATCGGTGTGATGGTGCCAACGCTGGAAAACGCGGTGTTCGCCGAATGCTGGCACGGCATCGA
GGAAGCGGCGCTGGCGGGCGGCTATTCGCTGATGCTGGTCACCAGCGGCTACGATCCGGCTCGCGAATGCGAGCGTGTGG
AGTACCTGCTGCGCCATCGCGTGGACGGCATGGTGCTGACCGTGGCCGACGCGGCGCACAGCACGGTGCTGGATCAACTC
GACGGCGAGGGCGTGCCATACGTGCTGGCGTACAACCAGGCCGGACCGCGCAGCCGGCGTCATTCGGTATCGGTGGACAA
CCGGCGCAGCGCCTGCGCCGGCGTGGAGGCCCTGATTGCCGCCGGGCACCGCCGCATCGTCGTGGTATCGGGCGCCTTCG
TCGCCTCGGACCGCGCGCGCCAGCGCTTTGCCGGCTATCAGGACGCCATGCGCGCGCACGGGCTAAGGCCCGCCGCGCCA
GTCTGCCTGCCATCGCACACCGCCAGCAATGCCGAACAGATCCGCGCGCTGGTCCGGGCAAACGATGCGCCCACCGCCTT
TTTCTGCACCAATGACCTGCTGGCCATCGGCGTGATCTCCGACCTCAGGCGCCTCGGCCTGAGCGTGCCGCGCGACATCT
CCGTGCTGGGCTATGACGGTATCGCGCTGGGCAGCGTGGTCGAACCGCCGCTGGCCACCGTCGTGCAACCCAATTCGGAG
ATCGGCGCCAGCGCCGTCGGCCGGCTGCTTGCCTGGCTGCACGATGGCGGACGAGCCTCGGCGGCGCCGCCGCGCGTCAC
GCTGCTGCCGCACGCACTGCGCGTCAACGGCACCGTGGCCGCTCCGCCATCAATGTAA

Upstream 100 bases:

>100_bases
CAAAATGCCATCCAGGCAGGGTGCAGGCGCCCGTCCGCCAGCCGCCTTCTGCGGCAGTGCAGCGACGGAATGTCTTGACG
CCCCGTTTTTTCCACCTTCA

Downstream 100 bases:

>100_bases
CCGCGCGTAACCGCGTGCGCATGTTGCATCCCCCACCCCTGTCCTCAACCAAGGAGCCTCTCATGCAACCTATTCCTTCC
TGGCGCCGCCCGCTGCGCTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKTFSSGALSVNRKDPAGGRPDTTGGATLIDVAQAARVSLATASRVFSSPHLVRDSTAQRVREAARRLSFRPNLLGSKLR
AQQTRMIGVMVPTLENAVFAECWHGIEEAALAGGYSLMLVTSGYDPARECERVEYLLRHRVDGMVLTVADAAHSTVLDQL
DGEGVPYVLAYNQAGPRSRRHSVSVDNRRSACAGVEALIAAGHRRIVVVSGAFVASDRARQRFAGYQDAMRAHGLRPAAP
VCLPSHTASNAEQIRALVRANDAPTAFFCTNDLLAIGVISDLRRLGLSVPRDISVLGYDGIALGSVVEPPLATVVQPNSE
IGASAVGRLLAWLHDGGRASAAPPRVTLLPHALRVNGTVAAPPSM

Sequences:

>Translated_365_residues
MKTFSSGALSVNRKDPAGGRPDTTGGATLIDVAQAARVSLATASRVFSSPHLVRDSTAQRVREAARRLSFRPNLLGSKLR
AQQTRMIGVMVPTLENAVFAECWHGIEEAALAGGYSLMLVTSGYDPARECERVEYLLRHRVDGMVLTVADAAHSTVLDQL
DGEGVPYVLAYNQAGPRSRRHSVSVDNRRSACAGVEALIAAGHRRIVVVSGAFVASDRARQRFAGYQDAMRAHGLRPAAP
VCLPSHTASNAEQIRALVRANDAPTAFFCTNDLLAIGVISDLRRLGLSVPRDISVLGYDGIALGSVVEPPLATVVQPNSE
IGASAVGRLLAWLHDGGRASAAPPRVTLLPHALRVNGTVAAPPSM
>Mature_365_residues
MKTFSSGALSVNRKDPAGGRPDTTGGATLIDVAQAARVSLATASRVFSSPHLVRDSTAQRVREAARRLSFRPNLLGSKLR
AQQTRMIGVMVPTLENAVFAECWHGIEEAALAGGYSLMLVTSGYDPARECERVEYLLRHRVDGMVLTVADAAHSTVLDQL
DGEGVPYVLAYNQAGPRSRRHSVSVDNRRSACAGVEALIAAGHRRIVVVSGAFVASDRARQRFAGYQDAMRAHGLRPAAP
VCLPSHTASNAEQIRALVRANDAPTAFFCTNDLLAIGVISDLRRLGLSVPRDISVLGYDGIALGSVVEPPLATVVQPNSE
IGASAVGRLLAWLHDGGRASAAPPRVTLLPHALRVNGTVAAPPSM

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=333, Percent_Identity=33.6336336336336, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790369, Length=315, Percent_Identity=30.1587301587302, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1789068, Length=322, Percent_Identity=31.6770186335404, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=31.7152103559871, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=29.903536977492, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787948, Length=308, Percent_Identity=26.6233766233766, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=28.8590604026846, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788474, Length=297, Percent_Identity=28.6195286195286, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786540, Length=306, Percent_Identity=28.7581699346405, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787580, Length=334, Percent_Identity=24.5508982035928, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787906, Length=261, Percent_Identity=31.4176245210728, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786268, Length=312, Percent_Identity=25, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38672; Mature: 38672

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFSSGALSVNRKDPAGGRPDTTGGATLIDVAQAARVSLATASRVFSSPHLVRDSTAQR
CCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VREAARRLSFRPNLLGSKLRAQQTRMIGVMVPTLENAVFAECWHGIEEAALAGGYSLMLV
HHHHHHHCCCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCHHHHHHCCCEEEEEE
TSGYDPARECERVEYLLRHRVDGMVLTVADAAHSTVLDQLDGEGVPYVLAYNQAGPRSRR
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HSVSVDNRRSACAGVEALIAAGHRRIVVVSGAFVASDRARQRFAGYQDAMRAHGLRPAAP
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHCCCCCCCC
VCLPSHTASNAEQIRALVRANDAPTAFFCTNDLLAIGVISDLRRLGLSVPRDISVLGYDG
EEECCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
IALGSVVEPPLATVVQPNSEIGASAVGRLLAWLHDGGRASAAPPRVTLLPHALRVNGTVA
EEECCCCCCCHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEECCEEC
APPSM
CCCCC
>Mature Secondary Structure
MKTFSSGALSVNRKDPAGGRPDTTGGATLIDVAQAARVSLATASRVFSSPHLVRDSTAQR
CCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VREAARRLSFRPNLLGSKLRAQQTRMIGVMVPTLENAVFAECWHGIEEAALAGGYSLMLV
HHHHHHHCCCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCHHHHHHCCCEEEEEE
TSGYDPARECERVEYLLRHRVDGMVLTVADAAHSTVLDQLDGEGVPYVLAYNQAGPRSRR
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HSVSVDNRRSACAGVEALIAAGHRRIVVVSGAFVASDRARQRFAGYQDAMRAHGLRPAAP
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHCCCCCCCC
VCLPSHTASNAEQIRALVRANDAPTAFFCTNDLLAIGVISDLRRLGLSVPRDISVLGYDG
EEECCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
IALGSVVEPPLATVVQPNSEIGASAVGRLLAWLHDGGRASAAPPRVTLLPHALRVNGTVA
EEECCCCCCCHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEECCEEC
APPSM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]