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The map label for this gene is 116695492

Identifier: 116695492

GI number: 116695492

Start: 1740314

End: 1741693

Strand: Direct

Name: 116695492

Synonym: H16_B1551

Alternate gene names: NA

Gene position: 1740314-1741693 (Clockwise)

Preceding gene: 116695491

Following gene: 116695498

Centisome position: 59.75

GC content: 69.13

Gene sequence:

>1380_bases
ATGCCACACCACCGGGCTGCCCCCCGCGCCGCCGCCGCGATTGCGGCCGCGGCGGTTCCATTGCCGCCCATCGACGACCC
GGCGGCAAGCCCGTTCCGCGGTCCGTTTGCCAATGCCACCGGCGTGCTGGCCGATTTGCTGGCCCGACACCGCGTGGTGC
TCCTGGGCGAAAGTACGCACGGCACCGCCGAGTTCTATCATGCCCGCGCTGCCCTGACAGCGCACCTGGTGGCCCGGCAC
GGCTTCCGCATCATCGCGGTCGAGGCAGACTGGCCAGATGCCGCGGCAGTCGACCGCCACGTGCGCGGCCGCCCGCCACA
GCCGGCCGAATCGCCCGGCGCAGCCTTTACACGCTTCCCGGTCTGGATGTGGCGCAACCTGGAGGTGGCGCGCTTTATCC
GCTGGCTGCACACGCACAATGAAACCCTGGCGCCTGCGCAGCGCACTGGATTCTTCGGCCTCGATATCTACAGCCTGCGC
GCTTCCATGGCTGCAGTGCTGGCCTACCTGGAGGGCGTAGATCCACAGGCCGCCCGAGCGGCGCGCGAGCGCTATGGCTG
CCTGGAACCGTGGGGCCGGGATCCGGCGCGCTATGGGCGTGCCGTGCTGCACGGCACGCATGCCGACTGCGAGGATGCCG
TCGTCGCACAGCTGCAGGCGCTGCTGGACAAACGGCTGGCCTATGCCCGGGCGGGTCACGAGGACTTTCTCGATGCCGCG
CAGAACGCGCGCCTGGTCGCTTCAGCCGAGCGCTACTACCGCGTGATGTATCACGGCAGCGACGACAGCTGGAACCTGCG
CGACACACATATGTTTGAAACCCTGGCGCATCTGCTGCAGGCGCATGGCCCGCAAGCGCGCGCGGTGGTATGGGCGCACA
ACTCGCATATCGGGGATGCTTCGCAGACCGAGATGGGCGCCAGCCAGGGGCAGCTGAGTATCGGCCAGCTGTGCCGCGAG
TCCTTCGGCGACGACGCCGCGCTGGTTGGCTTGAGCACTTACGACGGCACCGTCGCCGCGGCGACATCGTGGGACGGCCC
GATGGAAATCAAGCAAGTGCGCCCTGCCCGTGCCGACAGCTACGAGCATCTGTTCCATGCGGCCGGCCATGCGCAAGCCT
GGATCGACCTGCGGGGTCCGTCCGGCGGCGCCAACGGCGGCGTGCAGGCCGAAGTGCGTCAGCTGCTGATGCCGGCACGG
CAAGAGCGCTTTATCGGGGTGATCTACCGCCCCGAGACCGAACTGCAGAGCCACTATGCGCGCGCCACGCTGCCGCGGCA
ATTCGATCTGCTGTTGTGGTTCGACCGTACGCGCGCGGTTCCGGCGCTGCCGGCGGAGCCCGCGCCGGGCGCGCCGGAGA
CCTGGCCTTACGGGCTCTGA

Upstream 100 bases:

>100_bases
GCTTCGGCCACGACCCGCGCACCATTCCGGGCTGATCGCCGGCCACTCGTCAGGCCCCGCTGAAGACTCCGGCGCTGCTA
ATCCCGGATACCGATGCGAG

Downstream 100 bases:

>100_bases
AGTGGCCGCCTTGTCGCTTGCACGGACGCTCATCCGCCGGTGCGGTCCGGCGCAACCTGGATGCGATTGACGATCTCGCG
CACACCGTCACAGCCGCGGA

Product: erythromycin esterase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPHHRAAPRAAAAIAAAAVPLPPIDDPAASPFRGPFANATGVLADLLARHRVVLLGESTHGTAEFYHARAALTAHLVARH
GFRIIAVEADWPDAAAVDRHVRGRPPQPAESPGAAFTRFPVWMWRNLEVARFIRWLHTHNETLAPAQRTGFFGLDIYSLR
ASMAAVLAYLEGVDPQAARAARERYGCLEPWGRDPARYGRAVLHGTHADCEDAVVAQLQALLDKRLAYARAGHEDFLDAA
QNARLVASAERYYRVMYHGSDDSWNLRDTHMFETLAHLLQAHGPQARAVVWAHNSHIGDASQTEMGASQGQLSIGQLCRE
SFGDDAALVGLSTYDGTVAAATSWDGPMEIKQVRPARADSYEHLFHAAGHAQAWIDLRGPSGGANGGVQAEVRQLLMPAR
QERFIGVIYRPETELQSHYARATLPRQFDLLLWFDRTRAVPALPAEPAPGAPETWPYGL

Sequences:

>Translated_459_residues
MPHHRAAPRAAAAIAAAAVPLPPIDDPAASPFRGPFANATGVLADLLARHRVVLLGESTHGTAEFYHARAALTAHLVARH
GFRIIAVEADWPDAAAVDRHVRGRPPQPAESPGAAFTRFPVWMWRNLEVARFIRWLHTHNETLAPAQRTGFFGLDIYSLR
ASMAAVLAYLEGVDPQAARAARERYGCLEPWGRDPARYGRAVLHGTHADCEDAVVAQLQALLDKRLAYARAGHEDFLDAA
QNARLVASAERYYRVMYHGSDDSWNLRDTHMFETLAHLLQAHGPQARAVVWAHNSHIGDASQTEMGASQGQLSIGQLCRE
SFGDDAALVGLSTYDGTVAAATSWDGPMEIKQVRPARADSYEHLFHAAGHAQAWIDLRGPSGGANGGVQAEVRQLLMPAR
QERFIGVIYRPETELQSHYARATLPRQFDLLLWFDRTRAVPALPAEPAPGAPETWPYGL
>Mature_458_residues
PHHRAAPRAAAAIAAAAVPLPPIDDPAASPFRGPFANATGVLADLLARHRVVLLGESTHGTAEFYHARAALTAHLVARHG
FRIIAVEADWPDAAAVDRHVRGRPPQPAESPGAAFTRFPVWMWRNLEVARFIRWLHTHNETLAPAQRTGFFGLDIYSLRA
SMAAVLAYLEGVDPQAARAARERYGCLEPWGRDPARYGRAVLHGTHADCEDAVVAQLQALLDKRLAYARAGHEDFLDAAQ
NARLVASAERYYRVMYHGSDDSWNLRDTHMFETLAHLLQAHGPQARAVVWAHNSHIGDASQTEMGASQGQLSIGQLCRES
FGDDAALVGLSTYDGTVAAATSWDGPMEIKQVRPARADSYEHLFHAAGHAQAWIDLRGPSGGANGGVQAEVRQLLMPARQ
ERFIGVIYRPETELQSHYARATLPRQFDLLLWFDRTRAVPALPAEPAPGAPETWPYGL

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 50257; Mature: 50126

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHHRAAPRAAAAIAAAAVPLPPIDDPAASPFRGPFANATGVLADLLARHRVVLLGESTH
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCC
GTAEFYHARAALTAHLVARHGFRIIAVEADWPDAAAVDRHVRGRPPQPAESPGAAFTRFP
CHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCH
VWMWRNLEVARFIRWLHTHNETLAPAQRTGFFGLDIYSLRASMAAVLAYLEGVDPQAARA
HHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
ARERYGCLEPWGRDPARYGRAVLHGTHADCEDAVVAQLQALLDKRLAYARAGHEDFLDAA
HHHHCCCCCCCCCCHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QNARLVASAERYYRVMYHGSDDSWNLRDTHMFETLAHLLQAHGPQARAVVWAHNSHIGDA
HCCEEEEEHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SQTEMGASQGQLSIGQLCRESFGDDAALVGLSTYDGTVAAATSWDGPMEIKQVRPARADS
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCC
YEHLFHAAGHAQAWIDLRGPSGGANGGVQAEVRQLLMPARQERFIGVIYRPETELQSHYA
HHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHH
RATLPRQFDLLLWFDRTRAVPALPAEPAPGAPETWPYGL
HHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHHRAAPRAAAAIAAAAVPLPPIDDPAASPFRGPFANATGVLADLLARHRVVLLGESTH
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCC
GTAEFYHARAALTAHLVARHGFRIIAVEADWPDAAAVDRHVRGRPPQPAESPGAAFTRFP
CHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCH
VWMWRNLEVARFIRWLHTHNETLAPAQRTGFFGLDIYSLRASMAAVLAYLEGVDPQAARA
HHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
ARERYGCLEPWGRDPARYGRAVLHGTHADCEDAVVAQLQALLDKRLAYARAGHEDFLDAA
HHHHCCCCCCCCCCHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QNARLVASAERYYRVMYHGSDDSWNLRDTHMFETLAHLLQAHGPQARAVVWAHNSHIGDA
HCCEEEEEHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SQTEMGASQGQLSIGQLCRESFGDDAALVGLSTYDGTVAAATSWDGPMEIKQVRPARADS
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCC
YEHLFHAAGHAQAWIDLRGPSGGANGGVQAEVRQLLMPARQERFIGVIYRPETELQSHYA
HHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHH
RATLPRQFDLLLWFDRTRAVPALPAEPAPGAPETWPYGL
HHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]