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The map label for this gene is arcB [H]

Identifier: 116695482

GI number: 116695482

Start: 1729940

End: 1731934

Strand: Direct

Name: arcB [H]

Synonym: H16_B1541

Alternate gene names: 116695482

Gene position: 1729940-1731934 (Clockwise)

Preceding gene: 116695478

Following gene: 116695483

Centisome position: 59.4

GC content: 67.67

Gene sequence:

>1995_bases
ATGACAAGACCCCCCGAGGACCCGCAGCAACCCGCCGGAAGCGTACCTCGTCCCGACGCTGGCGAGCCATCGGGCGGGCG
TTCGCAAGAGATCCGGGCCGACCTGCCCGATGTGCCTTACCAGACCCTGGTGGACTCCGTGCAGGACTACGCCATCTTCA
CGCTCGACGTCGGCGGCCATGTCTCCAGCTGGAACAAGGGCGCGGCGCGCATCAAGGGCTATGCCCGCGAGGAGATCCTG
GGCAAGCATTTCTCGCAGTTCTACACGCCGGATGCGATCGCCCGGAGTTGGCCGCAAGCCGAACTGAAGGCCGCGGCCGA
ACAGGGCCGGTTCGAGGACGAGGGGTGGCGCGTGCGCAAGGACGGCAGCCGCTTCTGGGCCAATGTCGTCATCACCGCCC
TGAAGGACGCCGAGGGCCGGCTGATCGGCTTCGCCAAGGTCACGCGGGACATGACCGAGCGGCGCCGCGCCGCCGAGGCC
CTGCACCAGAGCGAAGAAACCCTGCGGCTGCTGGTGGAGGGGGTCAAGGATTACGCGATCTTCATGCTCGATCCCGGCGG
CCATATCGTCAGCTGGAATTCCGGTGCCTCTTATATCAAGGGCTACCGCCGCGACGAGATCATCGGCCGTCATTTCTCGG
TGTTCTATCCGCAGGAGGATGTTGCCGCTGGCAAGCCGTCACGGCACCTGGCACTGGCGCAGCGCGTCGGGCGCGTGGAA
GACGAAGGCTGGCGCGTGCGCAAGGATGGGTCGCTGTTCTGGGCCAATGTCACCCTGACAGCGGTATACGACGAGTCACG
CACGCTGCGCGGCTTTGCCAAGGTGACGCGGGACATGAGCGAGCGCCGCCGCCGCGAAGAGCTGGAACGCTCCAGCCAGC
GCATGAATGAGTTCCTGGCCACCCTTTCGCATGAACTGCGCAATCCGCTGGCGCCGGTGCACAGCGCGCTCGCGGCGATG
CGGCTGGCGCCGGAGGATGCGGTGCTGGCAAACCGGAGCCTGGCCATGATCGAGCGCCAGGTGACCCACCTGAGCCGGTT
GGTGGACGACCTGCTCGACATCGGGCGCATCACCTCCGGCCGGATCGAGCTGCGCATGGAGCCGGTCGAGTTCAACGAGA
TCATCGCGCTCGGCGTCGAGGCAGCGCAGCCGGCGCTGGATGCCAAGTCGCAGTGCGTCGAAGTGCGGACCCATGCCGGC
TCGATCCCAATGCGTGCCGACAAGACGCGGCTGGTGCAGGTCATGCAGAACCTGGTGCTCAATGCATCGAAATTCTCGCC
GCCCGGCTCGTCGGTGACGATCGCCACCACCATCCAGAACCGCACACTGCAGGTCCAGGTAATGGACCAGGGCTGTGGCA
TCGGGCCCCAGGCCATCGACGAGATCTTCAACCTGTTCATGCAGGAAAGCCGTCCGGGCACCGACTTGCATGGCGGGCTG
GGCATCGGCCTGTCGCTGTGCCGGTCACTGGTTGAGCTGCATGGCGGCACCATCTCTGCCGCCAGTGCCGGGGCGGGACA
AGGCAGCACCTTCACGCTGCGGCTGCCGCTGACGGCCTCGCACAAGGAGGACCCCCGGCCAGGAGCCGCACTGCCGGCCC
AGGGTCCGGTCGCACCCGAGTTGCAGGCGCAGCGCATCCTGCTGGTCGACGACAACCGCGACGCCGCCGACAGCCTGGCC
ATGCTGCTCGAGATATGCGGCCACGAGGTGACCATTGCCTACGACGGCGCCGAGGCCCTGCATGTGGCGCCCCGCTGCCG
CCCGCATATCGCGCTGATCGACCTGGCCATGCCCGGCATGGACGGCTTCGAAGTGGTGCGCGCCATGCGCCTCGTGGCCG
GCACCGAGCTGACGCGCTTCGTGGCGCTGACCGGCTTCGCCCAGCCGGCGGACCGGCAGCGTACCGAGGCCGCCGGCTTC
GACGCACACCTGGTCAAGCCGGTGGAGCTGGAAACGCTGTTCGGCACCATCGCCCGGCTGCGCCCGCCGGAATGA

Upstream 100 bases:

>100_bases
CCATTGGCCCTGCCAGGCTGCTTGCGGGGTATCCTTGCTACAAGACCAGCACCGGATGCGCTGGCGGGCCACGCCGGCAG
GACGCCGTTCAGGACATGCC

Downstream 100 bases:

>100_bases
CCCGTTCCGGCACCGAACCCGACCTTCGCCAATTCCAAACACGCGCCTGCCGGCGCTGCGACACACTGACGGCCATTCCA
TCGCAACAGATCACAGAAAG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MTRPPEDPQQPAGSVPRPDAGEPSGGRSQEIRADLPDVPYQTLVDSVQDYAIFTLDVGGHVSSWNKGAARIKGYAREEIL
GKHFSQFYTPDAIARSWPQAELKAAAEQGRFEDEGWRVRKDGSRFWANVVITALKDAEGRLIGFAKVTRDMTERRRAAEA
LHQSEETLRLLVEGVKDYAIFMLDPGGHIVSWNSGASYIKGYRRDEIIGRHFSVFYPQEDVAAGKPSRHLALAQRVGRVE
DEGWRVRKDGSLFWANVTLTAVYDESRTLRGFAKVTRDMSERRRREELERSSQRMNEFLATLSHELRNPLAPVHSALAAM
RLAPEDAVLANRSLAMIERQVTHLSRLVDDLLDIGRITSGRIELRMEPVEFNEIIALGVEAAQPALDAKSQCVEVRTHAG
SIPMRADKTRLVQVMQNLVLNASKFSPPGSSVTIATTIQNRTLQVQVMDQGCGIGPQAIDEIFNLFMQESRPGTDLHGGL
GIGLSLCRSLVELHGGTISAASAGAGQGSTFTLRLPLTASHKEDPRPGAALPAQGPVAPELQAQRILLVDDNRDAADSLA
MLLEICGHEVTIAYDGAEALHVAPRCRPHIALIDLAMPGMDGFEVVRAMRLVAGTELTRFVALTGFAQPADRQRTEAAGF
DAHLVKPVELETLFGTIARLRPPE

Sequences:

>Translated_664_residues
MTRPPEDPQQPAGSVPRPDAGEPSGGRSQEIRADLPDVPYQTLVDSVQDYAIFTLDVGGHVSSWNKGAARIKGYAREEIL
GKHFSQFYTPDAIARSWPQAELKAAAEQGRFEDEGWRVRKDGSRFWANVVITALKDAEGRLIGFAKVTRDMTERRRAAEA
LHQSEETLRLLVEGVKDYAIFMLDPGGHIVSWNSGASYIKGYRRDEIIGRHFSVFYPQEDVAAGKPSRHLALAQRVGRVE
DEGWRVRKDGSLFWANVTLTAVYDESRTLRGFAKVTRDMSERRRREELERSSQRMNEFLATLSHELRNPLAPVHSALAAM
RLAPEDAVLANRSLAMIERQVTHLSRLVDDLLDIGRITSGRIELRMEPVEFNEIIALGVEAAQPALDAKSQCVEVRTHAG
SIPMRADKTRLVQVMQNLVLNASKFSPPGSSVTIATTIQNRTLQVQVMDQGCGIGPQAIDEIFNLFMQESRPGTDLHGGL
GIGLSLCRSLVELHGGTISAASAGAGQGSTFTLRLPLTASHKEDPRPGAALPAQGPVAPELQAQRILLVDDNRDAADSLA
MLLEICGHEVTIAYDGAEALHVAPRCRPHIALIDLAMPGMDGFEVVRAMRLVAGTELTRFVALTGFAQPADRQRTEAAGF
DAHLVKPVELETLFGTIARLRPPE
>Mature_663_residues
TRPPEDPQQPAGSVPRPDAGEPSGGRSQEIRADLPDVPYQTLVDSVQDYAIFTLDVGGHVSSWNKGAARIKGYAREEILG
KHFSQFYTPDAIARSWPQAELKAAAEQGRFEDEGWRVRKDGSRFWANVVITALKDAEGRLIGFAKVTRDMTERRRAAEAL
HQSEETLRLLVEGVKDYAIFMLDPGGHIVSWNSGASYIKGYRRDEIIGRHFSVFYPQEDVAAGKPSRHLALAQRVGRVED
EGWRVRKDGSLFWANVTLTAVYDESRTLRGFAKVTRDMSERRRREELERSSQRMNEFLATLSHELRNPLAPVHSALAAMR
LAPEDAVLANRSLAMIERQVTHLSRLVDDLLDIGRITSGRIELRMEPVEFNEIIALGVEAAQPALDAKSQCVEVRTHAGS
IPMRADKTRLVQVMQNLVLNASKFSPPGSSVTIATTIQNRTLQVQVMDQGCGIGPQAIDEIFNLFMQESRPGTDLHGGLG
IGLSLCRSLVELHGGTISAASAGAGQGSTFTLRLPLTASHKEDPRPGAALPAQGPVAPELQAQRILLVDDNRDAADSLAM
LLEICGHEVTIAYDGAEALHVAPRCRPHIALIDLAMPGMDGFEVVRAMRLVAGTELTRFVALTGFAQPADRQRTEAAGFD
AHLVKPVELETLFGTIARLRPPE

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=530, Percent_Identity=26.4150943396226, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788713, Length=424, Percent_Identity=27.122641509434, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081816, Length=395, Percent_Identity=30.379746835443, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=31.0204081632653, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=28.0172413793103, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI145693157, Length=336, Percent_Identity=28.8690476190476, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=24.1286863270777, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=29.4354838709677, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=391, Percent_Identity=26.8542199488491, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081921, Length=274, Percent_Identity=24.8175182481752, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=26.8, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=264, Percent_Identity=26.5151515151515, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72905; Mature: 72774

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPPEDPQQPAGSVPRPDAGEPSGGRSQEIRADLPDVPYQTLVDSVQDYAIFTLDVGGH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCEEEEEECCCC
VSSWNKGAARIKGYAREEILGKHFSQFYTPDAIARSWPQAELKAAAEQGRFEDEGWRVRK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCCCCEEEC
DGSRFWANVVITALKDAEGRLIGFAKVTRDMTERRRAAEALHQSEETLRLLVEGVKDYAI
CCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FMLDPGGHIVSWNSGASYIKGYRRDEIIGRHFSVFYPQEDVAAGKPSRHLALAQRVGRVE
EEECCCCCEEEECCCHHHHHCCCHHHHHCCCEEEECCCHHHCCCCCHHHHHHHHHHCCCC
DEGWRVRKDGSLFWANVTLTAVYDESRTLRGFAKVTRDMSERRRREELERSSQRMNEFLA
CCCCEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSHELRNPLAPVHSALAAMRLAPEDAVLANRSLAMIERQVTHLSRLVDDLLDIGRITSG
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RIELRMEPVEFNEIIALGVEAAQPALDAKSQCVEVRTHAGSIPMRADKTRLVQVMQNLVL
EEEEEECCCCCCHHHEECHHHHCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NASKFSPPGSSVTIATTIQNRTLQVQVMDQGCGIGPQAIDEIFNLFMQESRPGTDLHGGL
CCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCH
GIGLSLCRSLVELHGGTISAASAGAGQGSTFTLRLPLTASHKEDPRPGAALPAQGPVAPE
HHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
LQAQRILLVDDNRDAADSLAMLLEICGHEVTIAYDGAEALHVAPRCRPHIALIDLAMPGM
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCEEEEEEECCCC
DGFEVVRAMRLVAGTELTRFVALTGFAQPADRQRTEAAGFDAHLVKPVELETLFGTIARL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHC
RPPE
CCCC
>Mature Secondary Structure 
TRPPEDPQQPAGSVPRPDAGEPSGGRSQEIRADLPDVPYQTLVDSVQDYAIFTLDVGGH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCEEEEEECCCC
VSSWNKGAARIKGYAREEILGKHFSQFYTPDAIARSWPQAELKAAAEQGRFEDEGWRVRK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCCCCEEEC
DGSRFWANVVITALKDAEGRLIGFAKVTRDMTERRRAAEALHQSEETLRLLVEGVKDYAI
CCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FMLDPGGHIVSWNSGASYIKGYRRDEIIGRHFSVFYPQEDVAAGKPSRHLALAQRVGRVE
EEECCCCCEEEECCCHHHHHCCCHHHHHCCCEEEECCCHHHCCCCCHHHHHHHHHHCCCC
DEGWRVRKDGSLFWANVTLTAVYDESRTLRGFAKVTRDMSERRRREELERSSQRMNEFLA
CCCCEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSHELRNPLAPVHSALAAMRLAPEDAVLANRSLAMIERQVTHLSRLVDDLLDIGRITSG
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RIELRMEPVEFNEIIALGVEAAQPALDAKSQCVEVRTHAGSIPMRADKTRLVQVMQNLVL
EEEEEECCCCCCHHHEECHHHHCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NASKFSPPGSSVTIATTIQNRTLQVQVMDQGCGIGPQAIDEIFNLFMQESRPGTDLHGGL
CCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCH
GIGLSLCRSLVELHGGTISAASAGAGQGSTFTLRLPLTASHKEDPRPGAALPAQGPVAPE
HHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
LQAQRILLVDDNRDAADSLAMLLEICGHEVTIAYDGAEALHVAPRCRPHIALIDLAMPGM
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCEEEEEEECCCC
DGFEVVRAMRLVAGTELTRFVALTGFAQPADRQRTEAAGFDAHLVKPVELETLFGTIARL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHC
RPPE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]