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The map label for this gene is lcr1 [H]

Identifier: 116695436

GI number: 116695436

Start: 1679168

End: 1680007

Strand: Direct

Name: lcr1 [H]

Synonym: H16_B1495

Alternate gene names: 116695436

Gene position: 1679168-1680007 (Clockwise)

Preceding gene: 116695434

Following gene: 116695437

Centisome position: 57.65

GC content: 67.02

Gene sequence:

>840_bases
ATGAACAAACATCTTGCTCGTCTGCTGACACCGATGGCGATCGGCTTCGGCCTGCTCGCCTCCACCCTGCCCGCCCTGGC
GGCACCGAAAGAAGTCCCGCTGGATGCCGCGGCGCTGTTCCGCCAGGCCGATGCCACCGGCACCATGGTGATCTACGACC
TGCGGCGCGACCGCATGCTGACCTACAACAAGCCGCGTGCGGCCACGCAGTACTCGCCGGCGTCGACCTTCAAGATCCTG
AACTCGATGATCGGCCTGGAGAGCGGTGCCGTGGCCGACGTCGACCATGACAAGCTGCCGTGGGACGGCAAGGTCTGGCT
GGTCGGCGGCAAGGCTGTCCTGCCCGACGCCTGCAACGCTGACGTGCCGCTGCGCGTCGCCTTCCCGAATTCCTGCGTGC
CGGCCTACCAGGCGCTGGCGCGGCGGGTTGGCAGCGCGGCCTACCAGCGCTACCTGACCGCATCGCACTATGGCAATGCC
AACAGCTCCGGCCAGGTCGACCGCTTCTGGCTGAACGGCACGCTGCAGATCTCCGCCTACCAGCAGATCGACTTCCTGAA
GGGCGTGGTACAGCGCACGCTGCCGTTCTCCCCGACCACCTTCAAGGCCGTGGACGACATCACTGTGATGGAGCGCACCG
CCGGCTACACCCTGCACGCCAAGACCGGGTGGGCCGATTCGGCCAAGCCCGCAGTGGGCTGGCTGGTGGGCTGGGTTGAG
CGTGGCGACGACGACTACCTGTTTGCACTCAATCTCGACATGGTGCAGCCCGAACACGCCAAGGCGCGCATGGAGATTGC
GCGCGCGGCGCTGCGGCAGGCGGGGGCGTTGCCGGATTGA

Upstream 100 bases:

>100_bases
AAGTTACAGCCAACGCGGTTGGCCTTATCCGGACGCTCTCCTATGCTGCGCACCACGGTCCGGGCCCGGATTGCCATCCC
CTCAACTCTTCTGCAAAGCC

Downstream 100 bases:

>100_bases
CGCAGCCGAAGGCGCCCGCCGCACGCGCGGCCGCCTGCAGTGACTGCCCTCGGATATTCACACAGGCAATTTCTCCCCCG
TATTTCAGATCCGTCTGATT

Product: Beta-lactamase LCR-1 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNKHLARLLTPMAIGFGLLASTLPALAAPKEVPLDAAALFRQADATGTMVIYDLRRDRMLTYNKPRAATQYSPASTFKIL
NSMIGLESGAVADVDHDKLPWDGKVWLVGGKAVLPDACNADVPLRVAFPNSCVPAYQALARRVGSAAYQRYLTASHYGNA
NSSGQVDRFWLNGTLQISAYQQIDFLKGVVQRTLPFSPTTFKAVDDITVMERTAGYTLHAKTGWADSAKPAVGWLVGWVE
RGDDDYLFALNLDMVQPEHAKARMEIARAALRQAGALPD

Sequences:

>Translated_279_residues
MNKHLARLLTPMAIGFGLLASTLPALAAPKEVPLDAAALFRQADATGTMVIYDLRRDRMLTYNKPRAATQYSPASTFKIL
NSMIGLESGAVADVDHDKLPWDGKVWLVGGKAVLPDACNADVPLRVAFPNSCVPAYQALARRVGSAAYQRYLTASHYGNA
NSSGQVDRFWLNGTLQISAYQQIDFLKGVVQRTLPFSPTTFKAVDDITVMERTAGYTLHAKTGWADSAKPAVGWLVGWVE
RGDDDYLFALNLDMVQPEHAKARMEIARAALRQAGALPD
>Mature_279_residues
MNKHLARLLTPMAIGFGLLASTLPALAAPKEVPLDAAALFRQADATGTMVIYDLRRDRMLTYNKPRAATQYSPASTFKIL
NSMIGLESGAVADVDHDKLPWDGKVWLVGGKAVLPDACNADVPLRVAFPNSCVPAYQALARRVGSAAYQRYLTASHYGNA
NSSGQVDRFWLNGTLQISAYQQIDFLKGVVQRTLPFSPTTFKAVDDITVMERTAGYTLHAKTGWADSAKPAVGWLVGWVE
RGDDDYLFALNLDMVQPEHAKARMEIARAALRQAGALPD

Specific function: This oxacillinase hydrolyzes methicillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30395; Mature: 30395

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHLARLLTPMAIGFGLLASTLPALAAPKEVPLDAAALFRQADATGTMVIYDLRRDRML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEE
TYNKPRAATQYSPASTFKILNSMIGLESGAVADVDHDKLPWDGKVWLVGGKAVLPDACNA
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEECCEECCCCCCC
DVPLRVAFPNSCVPAYQALARRVGSAAYQRYLTASHYGNANSSGQVDRFWLNGTLQISAY
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEHH
QQIDFLKGVVQRTLPFSPTTFKAVDDITVMERTAGYTLHAKTGWADSAKPAVGWLVGWVE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
RGDDDYLFALNLDMVQPEHAKARMEIARAALRQAGALPD
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNKHLARLLTPMAIGFGLLASTLPALAAPKEVPLDAAALFRQADATGTMVIYDLRRDRML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEE
TYNKPRAATQYSPASTFKILNSMIGLESGAVADVDHDKLPWDGKVWLVGGKAVLPDACNA
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEECCEECCCCCCC
DVPLRVAFPNSCVPAYQALARRVGSAAYQRYLTASHYGNANSSGQVDRFWLNGTLQISAY
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEHH
QQIDFLKGVVQRTLPFSPTTFKAVDDITVMERTAGYTLHAKTGWADSAKPAVGWLVGWVE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
RGDDDYLFALNLDMVQPEHAKARMEIARAALRQAGALPD
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1495394 [H]