Click here to switch to the map view.

The map label for this gene is ribB [H]

Identifier: 116695167

GI number: 116695167

Start: 1381300

End: 1382004

Strand: Direct

Name: ribB [H]

Synonym: H16_B1223

Alternate gene names: 116695167

Gene position: 1381300-1382004 (Clockwise)

Preceding gene: 116695165

Following gene: 116695168

Centisome position: 47.43

GC content: 68.37

Gene sequence:

>705_bases
ATGCTGAACAAGGAGCGTTTCATGCCTAGCCTTTCCACCGAAGCTGTTGCACCCGAGGTGTCCGCGGATCTTGCCGCCGA
TGCCGCCCCCCGTTCCCTGGCCGCGCGCATCGCGCAGGCGCTGGACGCCATGCGCGAAGGCCGTCCGGTCGTGCTGCTCG
ACGATGACGACCGCGAGAACGAGGCCGACCTGATTCTGGCCGCGGAACGCCTGACGAATGCCAATATGGCGATGATGATC
CGCGAATGCAGCGGCATCGTCTGCCTGTGCCTGACCGAGGACAAGGTGCGCAGCCTCGGCCTGCGGCCGATGGTCGAGCA
CAACCGCAGCCAGTATGGCACCGCCTTCACGGTATCGATCGAAGCCCGCGAAGGTGTCGGCACGGGTGTCAGCGCCGCCG
ACCGCATCACCACCATCCGCGCTGCCATTGCCGGGGATGCGGGCACCGATGCTGTGGTCAGCCCCGGCCATGTGTTTCCG
CTGGTGGCGCGCGACGGCGGGGTGCTGGTGCGCCGCGGCCATACCGAGGGCTCGGTCGACCTGGCCCGCATGGCAGGCCT
GTCACCGGCCGCGGTGCTGTGCGAGCTGATGAACCCCGACGGCACCATGGCACGCCGGCCGGAGGCGCTGGCCTTTGCCG
AGATGTACCAGCTACCGGTGCTGACCATCGAGGACCTGGTGGCCTGGCGCCGCCTGCACGACTGA

Upstream 100 bases:

>100_bases
TGCCTTGCGCCGCGCGCAGGGCGCGGCTGTTCGTGCGTGCGCTTCAGGCGCGGCGTGCGGCGCTGCAACTCCGTTGATCC
TTCCCCTGGAACGCCCATTG

Downstream 100 bases:

>100_bases
AAAGTCGCCGCCTGCACGCACCCCGGCATGCAAACGCGCCCGGGATGCGTGCTTCCTGTGCGACAATGCGGATCGCTTTT
TCCCGTCTATATGAGGGCAA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLNKERFMPSLSTEAVAPEVSADLAADAAPRSLAARIAQALDAMREGRPVVLLDDDDRENEADLILAAERLTNANMAMMI
RECSGIVCLCLTEDKVRSLGLRPMVEHNRSQYGTAFTVSIEAREGVGTGVSAADRITTIRAAIAGDAGTDAVVSPGHVFP
LVARDGGVLVRRGHTEGSVDLARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIEDLVAWRRLHD

Sequences:

>Translated_234_residues
MLNKERFMPSLSTEAVAPEVSADLAADAAPRSLAARIAQALDAMREGRPVVLLDDDDRENEADLILAAERLTNANMAMMI
RECSGIVCLCLTEDKVRSLGLRPMVEHNRSQYGTAFTVSIEAREGVGTGVSAADRITTIRAAIAGDAGTDAVVSPGHVFP
LVARDGGVLVRRGHTEGSVDLARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIEDLVAWRRLHD
>Mature_234_residues
MLNKERFMPSLSTEAVAPEVSADLAADAAPRSLAARIAQALDAMREGRPVVLLDDDDRENEADLILAAERLTNANMAMMI
RECSGIVCLCLTEDKVRSLGLRPMVEHNRSQYGTAFTVSIEAREGVGTGVSAADRITTIRAAIAGDAGTDAVVSPGHVFP
LVARDGGVLVRRGHTEGSVDLARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIEDLVAWRRLHD

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=60.3015075376884, Blast_Score=240, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=40.3940886699507, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 25065; Mature: 25065

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKERFMPSLSTEAVAPEVSADLAADAAPRSLAARIAQALDAMREGRPVVLLDDDDREN
CCCHHHCCCCCCCHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
EADLILAAERLTNANMAMMIRECSGIVCLCLTEDKVRSLGLRPMVEHNRSQYGTAFTVSI
CCCEEEEEHHHCCCCHHHHEECCCCEEEEEECHHHHHHCCCCHHHHCCCCCCCCEEEEEE
EAREGVGTGVSAADRITTIRAAIAGDAGTDAVVSPGHVFPLVARDGGVLVRRGHTEGSVD
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCEEEEECCCCCCCH
LARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIEDLVAWRRLHD
HHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNKERFMPSLSTEAVAPEVSADLAADAAPRSLAARIAQALDAMREGRPVVLLDDDDREN
CCCHHHCCCCCCCHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
EADLILAAERLTNANMAMMIRECSGIVCLCLTEDKVRSLGLRPMVEHNRSQYGTAFTVSI
CCCEEEEEHHHCCCCHHHHEECCCCEEEEEECHHHHHHCCCCHHHHCCCCCCCCEEEEEE
EAREGVGTGVSAADRITTIRAAIAGDAGTDAVVSPGHVFPLVARDGGVLVRRGHTEGSVD
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCEEEEECCCCCCCH
LARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIEDLVAWRRLHD
HHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA