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The map label for this gene is kdgK [H]

Identifier: 116695156

GI number: 116695156

Start: 1369636

End: 1370571

Strand: Direct

Name: kdgK [H]

Synonym: H16_B1212

Alternate gene names: 116695156

Gene position: 1369636-1370571 (Clockwise)

Preceding gene: 116695155

Following gene: 116695157

Centisome position: 47.03

GC content: 69.12

Gene sequence:

>936_bases
ATGAGCATCGATATCCTGGCCTACGGCGAACCGCTGGTGGAGTTCAACCAACAGCCCGACGATCCATCGCGCTACCTGCA
AGGCTTTGGCGGCGACACTTCCAACTTCTGCATTGCCGCTGCGCGCCAGGGCGCCAGCACCGGCTATATCTGCGCGGTCG
GTGCCGACACCTTCGGCGAGCGCCTGCGCGCGCTATGGACGCAGGAGCGGGTCGATACCCGCCACGTGCGCGTCGACCCG
AGCGCGCCTACCGGGGTCTACTTTGTCTCGCACGACAACCACGGCCACCGCTTCGATTACCTGCGCGAAGGCTCTGCTGC
CAGCCGCTACCAGCACGAGCATCTGCCGCTGGGCGCGATCGCCGCGGCGCGCTACCTGCACCTGTCGGGCATCAGCCTGG
CCATCAGCACCAGCGCCTGCGATGCCGGGCTGGACGCGATGGAGCATGCGCGCAAGGCCGGCACCAAGGTCACGCTGGAC
ACCAACCTGCGGCTGCGGCTGTGGTCGCTGGCGCGCGCGCGCGGCATCATGCGCGAGGCCCTGATGCTGACCGACGTGTG
CCTGCCCAGCTGGGATGACATCACCGTGCTGACCGGGTTGGACGACCGCGACGCCATCGTCGACTACCTGCTGGGCTGCG
GCATCGGCCTGGTCGCGCTGAAGCTGGGCGAAGAGGGCTCCTATGTGGCCACGCCAGAGTCGCGCGCGCTGGTGCCGCCT
TATCCGGTCAAGCCGGTCGATGCCACCGGGGCGGGCGACTGCTTCGGCGGCAGCTTTGTTGCGCGCCTGGCCGCGGGTGC
CGACCCGTTCGAGGCGGCGCGTTATGCCAACGTGGCTGCCGCGCTGTCGACCACCGGTTATGGCGCGGTGGCGCCGATCC
CCGACGCCCAGACCGTGCTGGGCCGGCTGGCACAGTCGGTGTCGGTGATCGCATGA

Upstream 100 bases:

>100_bases
CCGTGCCTGACTTTCGACAAGTGGCGCCATATCCCGGTGCTGGACAGCGAAATGCGCGTGATCGACATCGTGCAAACCTT
CTTCTGAGGCAGGCAGCCCC

Downstream 100 bases:

>100_bases
CCCGGTTGGCCTGAACTCCTGCTTCCCTGAAACCCTGCTCCTGCACTCCCTACTCCGAGACAGCCATGCAAAACCAGACT
TCCCCGCTGCTTCAACGCCT

Product: 2-keto-3-deoxygluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSIDILAYGEPLVEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGASTGYICAVGADTFGERLRALWTQERVDTRHVRVDP
SAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAAARYLHLSGISLAISTSACDAGLDAMEHARKAGTKVTLD
TNLRLRLWSLARARGIMREALMLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGSYVATPESRALVPP
YPVKPVDATGAGDCFGGSFVARLAAGADPFEAARYANVAAALSTTGYGAVAPIPDAQTVLGRLAQSVSVIA

Sequences:

>Translated_311_residues
MSIDILAYGEPLVEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGASTGYICAVGADTFGERLRALWTQERVDTRHVRVDP
SAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAAARYLHLSGISLAISTSACDAGLDAMEHARKAGTKVTLD
TNLRLRLWSLARARGIMREALMLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGSYVATPESRALVPP
YPVKPVDATGAGDCFGGSFVARLAAGADPFEAARYANVAAALSTTGYGAVAPIPDAQTVLGRLAQSVSVIA
>Mature_310_residues
SIDILAYGEPLVEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGASTGYICAVGADTFGERLRALWTQERVDTRHVRVDPS
APTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAAARYLHLSGISLAISTSACDAGLDAMEHARKAGTKVTLDT
NLRLRLWSLARARGIMREALMLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGSYVATPESRALVPPY
PVKPVDATGAGDCFGGSFVARLAAGADPFEAARYANVAAALSTTGYGAVAPIPDAQTVLGRLAQSVSVIA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=251, Percent_Identity=29.8804780876494, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87082281, Length=306, Percent_Identity=30.3921568627451, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081971, Length=310, Percent_Identity=23.8709677419355, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790193, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 33043; Mature: 32911

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDILAYGEPLVEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGASTGYICAVGADTFGE
CEEEEEECCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHHH
RLRALWTQERVDTRHVRVDPSAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAI
HHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHCCCHHHH
AAARYLHLSGISLAISTSACDAGLDAMEHARKAGTKVTLDTNLRLRLWSLARARGIMREA
HHHHHHEECCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHHH
LMLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGSYVATPESRALVPP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCC
YPVKPVDATGAGDCFGGSFVARLAAGADPFEAARYANVAAALSTTGYGAVAPIPDAQTVL
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
GRLAQSVSVIA
HHHHHHHHHCC
>Mature Secondary Structure 
SIDILAYGEPLVEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGASTGYICAVGADTFGE
EEEEEECCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHHH
RLRALWTQERVDTRHVRVDPSAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAI
HHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHCCCHHHH
AAARYLHLSGISLAISTSACDAGLDAMEHARKAGTKVTLDTNLRLRLWSLARARGIMREA
HHHHHHEECCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHHH
LMLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGSYVATPESRALVPP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCC
YPVKPVDATGAGDCFGGSFVARLAAGADPFEAARYANVAAALSTTGYGAVAPIPDAQTVL
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
GRLAQSVSVIA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157608 [H]