Click here to switch to the map view.

The map label for this gene is yngI [H]

Identifier: 116695093

GI number: 116695093

Start: 1302465

End: 1304099

Strand: Direct

Name: yngI [H]

Synonym: H16_B1148

Alternate gene names: 116695093

Gene position: 1302465-1304099 (Clockwise)

Preceding gene: 116695089

Following gene: 116695097

Centisome position: 44.72

GC content: 67.83

Gene sequence:

>1635_bases
ATGCCCACCGATTTCGACAGCGGCCTGGCCCGCAACGCGGCCAACTTCGTGCCGCTTACGCCCATCGACTTCCTGGTCCG
CGCCGCCGAGGTGTACGGCCAGCGCCTGGCCATCGTGCACGGCCCGCTGCGCCAGAACTGGCGCGACACCTATGCGCGCG
CACGGCGCCTAGCCAGCGCGCTGGCGCGTGCCGGCATCGGCAAGGGCGATACCGTGGCCGCGCTGCTGCCCAATACGCCG
GCCATGGTGGAGGCGCATTTCGGCGTGCCGATGGCGGGCGCCGTGCTCAATGCGCTCAATATCCGCCTCGACGCCGCCAA
CCTGGTCTTCATGCTGCGCCATGGCGAGGCGCGCGTGCTGCTGGCCGATACCGAGTTTGCCGACCTGGCGCGCCAGATGG
CGCTGGAGATCCCCGGCCTGAAGGTCATCGCCGTGCATGACGTGCTGGGCCCGCAGGAGGCGCCGTTCGGCGACACCGAT
TACGAAGCCTTCCTCGCCTCGGGCGACTCGGACTACGCGTGGCACATGCCGGCCGACGAGTGGGAAGCCATCGCGCTGAA
CTACACCTCGGGCACCACCGGCGACCCCAAGGGCGTGGTCTACCACCACCGCGGCGCGGCCATCAATGCCGTGTCCAACA
TCCTCGAGTGGGATTTGCCCAAGCACCCGGTCTACCTGTGGACGCTGCCGATGTTCCACTGCAATGGCTGGTGCTTCCCG
TGGACCGTTGCCGCGCGCGCGGGCGTCAACGTGTGCCTGCGCAAGTTCGAGCCCAGGCTGGTATTCGACCTGATGCGCGA
AGAGGGCGTGACCCACTACTGCGCCGCGCCGATCGTGCATACCGCGCTGGTCAATGCGCCCGCCGCGTGGCGCGAGGGCG
TGCGCGGCCCGGTGCGCGGCATGGTGGCCGGCGCGCCGCCGCCGGCCGCGGTGCTGGCGCAGATGGAGGCGATGGGGTTC
GAGCTGACCCATGTCTATGGCCTGACCGAGGTCTACGGCCCGGCCGCGGTCTGCGCCGAGCAGGATGACTGGAGCACGCT
GTCCGAGCAAGACCGCGCGGTCAGGAAGGCGCGTCAGGGCGTGCGCTATCACCTGCAGTCGCAGGTGGCGGTGCTCGATC
CCGATTCCATGCAGCCGGTGCCGGCCGATGGCGAGACCATCGGCGAGATCATGTTCCGCGGCAATATCTGCATGAAGGGC
TACCTCAAGAACGAGAAGGCCACGCGCGAGGCCTTTGCCGGCGGCTGGTTCCATACCGGCGACCTGGGTGTGTGCATGCC
CGATGGCTATATCAAGATCAAGGACCGCAGCAAGGACATCATTATTTCCGGCGGCGAGAACATCTCCAGCGTTGAGGTGG
AGGACGCGCTCTACCGGCATCCCGCGGTGCTGGCCGCCGCAGTGGTGGCGCAGCCCGATGCCAGGTGGGGCGAGACCCCA
TGCGCGTTTGTCGAACTGAAGGACGGCGCCAGCGTCAGCGCGGAAGAACTGATCGCGCATTGCCGCACGCTGCTGGCGGG
CTTCAAGGTGCCCAAGGCGGTCTACTTCGGGCCGCTGCCCAAGACCTCGACCGGCAAGATCCAGAAGTTCGAGCTGCGCC
GCAAGGTGAAGTCGGATTCGGCGATCGACGTTTGA

Upstream 100 bases:

>100_bases
GCCCCGGACATCGCTGCACCCATGCAGCGCATTGACAGCATCACGCGGCCTGTTGCGCGGCCCTGCCGCCAACGCCGCCA
GATACGCGGAGACACAAGCA

Downstream 100 bases:

>100_bases
TGGGCTGAAGCGGCGCTGGTGCAGCGCCGCTATTGCAGCGCCGCGTCCTCGGCATCGTGCAGGCCGGCGATGTGCGTGTC
GATGGCCTCGCGCCCCCAGG

Product: acyl-CoA synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MPTDFDSGLARNAANFVPLTPIDFLVRAAEVYGQRLAIVHGPLRQNWRDTYARARRLASALARAGIGKGDTVAALLPNTP
AMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEARVLLADTEFADLARQMALEIPGLKVIAVHDVLGPQEAPFGDTD
YEAFLASGDSDYAWHMPADEWEAIALNYTSGTTGDPKGVVYHHRGAAINAVSNILEWDLPKHPVYLWTLPMFHCNGWCFP
WTVAARAGVNVCLRKFEPRLVFDLMREEGVTHYCAAPIVHTALVNAPAAWREGVRGPVRGMVAGAPPPAAVLAQMEAMGF
ELTHVYGLTEVYGPAAVCAEQDDWSTLSEQDRAVRKARQGVRYHLQSQVAVLDPDSMQPVPADGETIGEIMFRGNICMKG
YLKNEKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDARWGETP
CAFVELKDGASVSAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRRKVKSDSAIDV

Sequences:

>Translated_544_residues
MPTDFDSGLARNAANFVPLTPIDFLVRAAEVYGQRLAIVHGPLRQNWRDTYARARRLASALARAGIGKGDTVAALLPNTP
AMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEARVLLADTEFADLARQMALEIPGLKVIAVHDVLGPQEAPFGDTD
YEAFLASGDSDYAWHMPADEWEAIALNYTSGTTGDPKGVVYHHRGAAINAVSNILEWDLPKHPVYLWTLPMFHCNGWCFP
WTVAARAGVNVCLRKFEPRLVFDLMREEGVTHYCAAPIVHTALVNAPAAWREGVRGPVRGMVAGAPPPAAVLAQMEAMGF
ELTHVYGLTEVYGPAAVCAEQDDWSTLSEQDRAVRKARQGVRYHLQSQVAVLDPDSMQPVPADGETIGEIMFRGNICMKG
YLKNEKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDARWGETP
CAFVELKDGASVSAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRRKVKSDSAIDV
>Mature_543_residues
PTDFDSGLARNAANFVPLTPIDFLVRAAEVYGQRLAIVHGPLRQNWRDTYARARRLASALARAGIGKGDTVAALLPNTPA
MVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEARVLLADTEFADLARQMALEIPGLKVIAVHDVLGPQEAPFGDTDY
EAFLASGDSDYAWHMPADEWEAIALNYTSGTTGDPKGVVYHHRGAAINAVSNILEWDLPKHPVYLWTLPMFHCNGWCFPW
TVAARAGVNVCLRKFEPRLVFDLMREEGVTHYCAAPIVHTALVNAPAAWREGVRGPVRGMVAGAPPPAAVLAQMEAMGFE
LTHVYGLTEVYGPAAVCAEQDDWSTLSEQDRAVRKARQGVRYHLQSQVAVLDPDSMQPVPADGETIGEIMFRGNICMKGY
LKNEKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDARWGETPC
AFVELKDGASVSAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRRKVKSDSAIDV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=535, Percent_Identity=28.411214953271, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI187761345, Length=547, Percent_Identity=29.2504570383912, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI187761343, Length=547, Percent_Identity=29.2504570383912, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI157311624, Length=512, Percent_Identity=25.1953125, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI157311622, Length=512, Percent_Identity=25.1953125, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI122937307, Length=509, Percent_Identity=27.3084479371316, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI58082049, Length=509, Percent_Identity=24.950884086444, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI42544132, Length=513, Percent_Identity=26.1208576998051, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI38505220, Length=499, Percent_Identity=25.0501002004008, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI115511026, Length=515, Percent_Identity=24.2718446601942, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI42794756, Length=485, Percent_Identity=23.7113402061856, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI42794760, Length=485, Percent_Identity=23.7113402061856, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI42794758, Length=485, Percent_Identity=23.7113402061856, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI40807491, Length=528, Percent_Identity=24.2424242424242, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI28416953, Length=130, Percent_Identity=34.6153846153846, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI8923896, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI253970489, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI145693145, Length=513, Percent_Identity=32.1637426900585, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI221142682, Length=523, Percent_Identity=28.1070745697897, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788107, Length=548, Percent_Identity=27.7372262773723, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1786810, Length=546, Percent_Identity=26.5567765567766, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788595, Length=512, Percent_Identity=25.1953125, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994703, Length=533, Percent_Identity=27.9549718574109, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71994690, Length=533, Percent_Identity=27.9549718574109, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71994694, Length=533, Percent_Identity=27.9549718574109, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17560308, Length=530, Percent_Identity=28.1132075471698, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17538037, Length=521, Percent_Identity=24.5681381957774, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17558820, Length=500, Percent_Identity=27.4, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17557194, Length=512, Percent_Identity=24.0234375, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17559526, Length=509, Percent_Identity=24.950884086444, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32563687, Length=516, Percent_Identity=25.3875968992248, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=512, Percent_Identity=23.046875, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17560140, Length=537, Percent_Identity=23.463687150838, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71983001, Length=546, Percent_Identity=24.5421245421245, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982997, Length=546, Percent_Identity=24.5421245421245, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510401, Length=182, Percent_Identity=32.967032967033, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985884, Length=601, Percent_Identity=23.7936772046589, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319699, Length=346, Percent_Identity=27.4566473988439, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6323182, Length=143, Percent_Identity=35.6643356643357, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581924, Length=551, Percent_Identity=27.2232304900181, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18859661, Length=517, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21355181, Length=504, Percent_Identity=25.5952380952381, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922652, Length=511, Percent_Identity=26.027397260274, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648260, Length=497, Percent_Identity=22.7364185110664, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356947, Length=504, Percent_Identity=21.8253968253968, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24648257, Length=546, Percent_Identity=23.992673992674, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358303, Length=482, Percent_Identity=21.5767634854772, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356441, Length=463, Percent_Identity=20.5183585313175, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281365686, Length=475, Percent_Identity=21.6842105263158, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130357, Length=510, Percent_Identity=22.3529411764706, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653035, Length=465, Percent_Identity=22.7956989247312, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 59191; Mature: 59060

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDFDSGLARNAANFVPLTPIDFLVRAAEVYGQRLAIVHGPLRQNWRDTYARARRLASA
CCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHH
LARAGIGKGDTVAALLPNTPAMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEARVL
HHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
LADTEFADLARQMALEIPGLKVIAVHDVLGPQEAPFGDTDYEAFLASGDSDYAWHMPADE
EECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHEECCCCCEEECCCCCC
WEAIALNYTSGTTGDPKGVVYHHRGAAINAVSNILEWDLPKHPVYLWTLPMFHCNGWCFP
CCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECHHHCCCCCCH
WTVAARAGVNVCLRKFEPRLVFDLMREEGVTHYCAAPIVHTALVNAPAAWREGVRGPVRG
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHC
MVAGAPPPAAVLAQMEAMGFELTHVYGLTEVYGPAAVCAEQDDWSTLSEQDRAVRKARQG
EECCCCCHHHHHHHHHHCCEEEEHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHHH
VRYHLQSQVAVLDPDSMQPVPADGETIGEIMFRGNICMKGYLKNEKATREAFAGGWFHTG
HHEEHHCCEEEECCCCCCCCCCCCHHHHHHHEECCEEEEEEECCCHHHHHHHCCCCEEEC
DLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDARWGETP
CEEEECCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCCCCC
CAFVELKDGASVSAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRRKVKSDS
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCC
AIDV
CCCC
>Mature Secondary Structure 
PTDFDSGLARNAANFVPLTPIDFLVRAAEVYGQRLAIVHGPLRQNWRDTYARARRLASA
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHH
LARAGIGKGDTVAALLPNTPAMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEARVL
HHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
LADTEFADLARQMALEIPGLKVIAVHDVLGPQEAPFGDTDYEAFLASGDSDYAWHMPADE
EECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHEECCCCCEEECCCCCC
WEAIALNYTSGTTGDPKGVVYHHRGAAINAVSNILEWDLPKHPVYLWTLPMFHCNGWCFP
CCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECHHHCCCCCCH
WTVAARAGVNVCLRKFEPRLVFDLMREEGVTHYCAAPIVHTALVNAPAAWREGVRGPVRG
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHC
MVAGAPPPAAVLAQMEAMGFELTHVYGLTEVYGPAAVCAEQDDWSTLSEQDRAVRKARQG
EECCCCCHHHHHHHHHHCCEEEEHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHHH
VRYHLQSQVAVLDPDSMQPVPADGETIGEIMFRGNICMKGYLKNEKATREAFAGGWFHTG
HHEEHHCCEEEECCCCCCCCCCCCHHHHHHHEECCEEEEEEECCCHHHHHHHCCCCEEEC
DLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDARWGETP
CEEEECCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCCCCC
CAFVELKDGASVSAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRRKVKSDS
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCC
AIDV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]