| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is polS [H]
Identifier: 116695085
GI number: 116695085
Start: 1293931
End: 1294698
Strand: Direct
Name: polS [H]
Synonym: H16_B1140
Alternate gene names: 116695085
Gene position: 1293931-1294698 (Clockwise)
Preceding gene: 116695082
Following gene: 116695086
Centisome position: 44.43
GC content: 70.57
Gene sequence:
>768_bases ATGCAGAACCTCTTCGACCTTGGCGGCCGCGTTGCCGTCATCACCGGCTCCACCCGTGGCATGGGCCTGGAAATGGCGCG CGCGCTTGGCGCGGCCGGCGCCGCCGTGGTGGTGTCCGGGCGCGATGCAGGCGCGGCGCGCGACGCCGCCAGTCAGCTGG AGGCCGAGGGCATCCGCGCCACCGGCATCGCCTGCGATATCGCCGATGTCGACAGCGTGCGCGCCTTCGCGGAGCAGGCG CTGGCCGCGTATGGGCGCGTCGATGCACTGGTGCTCAATGCCGCCGCGAGCGGCCAGCCCGGATCGATGCTGAGCCAGGG ACCCGAGGTGTTCGATGCGGCCATGGCGGGCAATGTGCGCGGCAACCTGGTGCTGGTGAACGCCCTGGCGCCGCAGATGA TCAGTCGCCATGACGGATCCATCATCTTCATGTCGAGCATTGCCGCCAAGCGTGGCTCTGCCTTCCTGGGGATGTACAGC GTGACCAAGGCCGCCATCGACCAGGCGGTACGCAGCCTGGCGCTGGAGCTGGGGCCGTCCGGCATCAACGTCAACGCAAT CAATCCCGGCCCGGTGCGCACCGAGTTCTCGCGCGACGCGCTGTGGGGCGATCCGGAGCGCGAGGCGCGGCTGGCTGCGG GCGTGCCGATGCGGCGCATCGGCGAGGCCAGCGATGTCGCGGGTCTTGCCGTCCTGCTGGCGGCACCGGCCGGGCGCTTT ATCCACGGGCAGAGCATCGGCGTGGATGGCGGGCTGTCGGCGCAGTAA
Upstream 100 bases:
>100_bases ATAGATGATTGTCATCATCTATGTGCAGTCTCCCTTTCGCCGCATTTGTGCCGATGTGTGTCCAGGTGCCGGCTCCCAAT CTTCACAGGAGTGATCAGTC
Downstream 100 bases:
>100_bases CCCCGTGCCGTGGCGGGCGGCCGATGCTCAGTGTCATTGGCCGGGCGGAGGCGAAATGTGCATACATAGGAACGCGCCTT CAGCACGTTGAAGGGTTTTC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 255; Mature: 255
Protein sequence:
>255_residues MQNLFDLGGRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIADVDSVRAFAEQA LAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVNALAPQMISRHDGSIIFMSSIAAKRGSAFLGMYS VTKAAIDQAVRSLALELGPSGINVNAINPGPVRTEFSRDALWGDPEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRF IHGQSIGVDGGLSAQ
Sequences:
>Translated_255_residues MQNLFDLGGRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIADVDSVRAFAEQA LAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVNALAPQMISRHDGSIIFMSSIAAKRGSAFLGMYS VTKAAIDQAVRSLALELGPSGINVNAINPGPVRTEFSRDALWGDPEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRF IHGQSIGVDGGLSAQ >Mature_255_residues MQNLFDLGGRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIADVDSVRAFAEQA LAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVNALAPQMISRHDGSIIFMSSIAAKRGSAFLGMYS VTKAAIDQAVRSLALELGPSGINVNAINPGPVRTEFSRDALWGDPEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRF IHGQSIGVDGGLSAQ
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=35.9183673469388, Blast_Score=155, Evalue=3e-38, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=36.144578313253, Blast_Score=154, Evalue=1e-37, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.4516129032258, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=38.5416666666667, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=29.0566037735849, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI126723191, Length=203, Percent_Identity=33.0049261083744, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=33.0708661417323, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=33.4975369458128, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=29.7959183673469, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=31.7391304347826, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=27.4900398406374, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=29.4354838709677, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=29.7619047619048, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI186928839, Length=217, Percent_Identity=31.3364055299539, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=34.1836734693878, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI209862901, Length=204, Percent_Identity=30.3921568627451, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI19923983, Length=204, Percent_Identity=30.3921568627451, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI223718074, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=24.2574257425743, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI32455239, Length=180, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI5031765, Length=180, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI302344755, Length=110, Percent_Identity=35.4545454545455, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=34.1269841269841, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=35.0393700787402, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.4347826086957, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=31.3492063492063, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=30.7392996108949, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=31.413612565445, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.1497975708502, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.9212598425197, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=28.8537549407115, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=29.1497975708502, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.0155642023346, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=30.9236947791165, Blast_Score=131, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.2788844621514, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=31.9230769230769, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=30.46875, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.5301204819277, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=30.6818181818182, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=30.5019305019305, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=31.5985130111524, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=31.6176470588235, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=30.1158301158301, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.4511278195489, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=29.3893129770992, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.2442748091603, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.9242424242424, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=28.968253968254, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=29.5880149812734, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=28.6259541984733, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=27.9411764705882, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17567345, Length=189, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17558006, Length=216, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17532805, Length=223, Percent_Identity=27.3542600896861, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193207620, Length=223, Percent_Identity=26.457399103139, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=25.390625, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555612, Length=223, Percent_Identity=30.9417040358744, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561272, Length=253, Percent_Identity=25.296442687747, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71992402, Length=222, Percent_Identity=25.6756756756757, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17536651, Length=268, Percent_Identity=24.6268656716418, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71997099, Length=242, Percent_Identity=24.7933884297521, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI32565532, Length=211, Percent_Identity=24.1706161137441, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=25.7894736842105, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=28.4, Blast_Score=92, Evalue=6e-20, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.9317269076305, Blast_Score=145, Evalue=4e-35, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=33.7349397590361, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=34.1269841269841, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=32.4, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=28.9156626506024, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.1428571428571, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=31.4741035856574, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=28.1853281853282, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI21357673, Length=246, Percent_Identity=27.2357723577236, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24640492, Length=205, Percent_Identity=25.3658536585366, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI45554248, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640117, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076371, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641232, Length=247, Percent_Identity=27.1255060728745, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=28.8, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 25810; Mature: 25810
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQNLFDLGGRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRA CCCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEE TGIACDIADVDSVRAFAEQALAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVR CCEEEECCCHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCC GNLVLVNALAPQMISRHDGSIIFMSSIAAKRGSAFLGMYSVTKAAIDQAVRSLALELGPS CCEEEEECHHHHHHHCCCCCEEEEECHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC GINVNAINPGPVRTEFSRDALWGDPEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRF CCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCE IHGQSIGVDGGLSAQ EECCCCCCCCCCCCC >Mature Secondary Structure MQNLFDLGGRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRA CCCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEE TGIACDIADVDSVRAFAEQALAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVR CCEEEECCCHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCC GNLVLVNALAPQMISRHDGSIIFMSSIAAKRGSAFLGMYSVTKAAIDQAVRSLALELGPS CCEEEEECHHHHHHHCCCCCEEEEECHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC GINVNAINPGPVRTEFSRDALWGDPEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRF CCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCE IHGQSIGVDGGLSAQ EECCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]