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The map label for this gene is acrC9 [H]

Identifier: 116695060

GI number: 116695060

Start: 1265358

End: 1266902

Strand: Direct

Name: acrC9 [H]

Synonym: H16_B1115

Alternate gene names: 116695060

Gene position: 1265358-1266902 (Clockwise)

Preceding gene: 116695059

Following gene: 116695061

Centisome position: 43.45

GC content: 71.52

Gene sequence:

>1545_bases
ATGGTGATCAACATGAATGCCCCTGCATTTTCGACAACAAATTGGCTGCCTAAGCTGGCGACCCTGGCGGCAGCGCTGAT
CCTTGCGGGCTGCTCGCTGGCCCCGACCTACAAGGTGCCCGAAACGGCCACCGTGCCGGCCTTCAAGGAGGCCGAGGCCG
CCCAGGCCGAAGGCGCGCAATGGAAGACCGCGACGCCGGCCGAAGGCCAGCATCGCGGCGACTGGTGGAAGATCTTTGGC
GATGCCGAACTGGACCGCCTGATCGACGCGGCTGGCAGCTCCAACCAGGATCTGGCGATTGCCGCTGCCCGCCTGAAGCA
GGCGCGGGCCTTCACGGGTGCCACTGAGGCGGACCTGTACCCGCAACTGAGCGTGGGGCTGGACCCGACACGCGCGCAGC
CGTCGGCGGCCTCGCAAGGCTTGCCTGACGGCACGCGGGTGCCGCCGCAGACGGTGCTGAAGGCGCGCGCGTTCGCCAGC
TATGAGCTCGACCTGTTCGGCCGCGTCGCGTCCAGCGTCAACGCCGCCCGGGCTGAAGGCGAGGCCGCGGAGGACCTGTA
CCGCTCGGTGCAGCTGGCGCTGCAGGCCGACGTGGCGCAGGCGTACTTCGCGCTGCGCACGCTGGACAGCGAGCGCGACC
TGCTCAATGCCACCATCAAACTGCGCGAGGATGCGCTGTCATTGCTGAAGAAGCGCTATGACGCCGGCGAGACCACCGAC
CTGGATCCCGCCCGTGCCGAAGCTGAACTCGGCACCGCGCGCGCGGACCTGGCCGGCATCGAACGCCGCCGTGCCAACCA
GGAGCATGCGCTGGCGGTGCTGACCGGCGTGCCGCCGGCGGCATTCTCGCTGCCGGCGCGCCCGTTCGACGCGGCGCCGA
TCGCGATTCCCGCCGGGTTGCCGTCCGAGCTGCTGGAGCGCCGCCCCGACATCGCCGCGGCGGAACGCCAGATGGCCGCG
GCCAACGCGCGCATCGGCGTGGCCAAGGCGGCGTTCTTCCCGCGCATCACGCTGACGGGGCTGTTCGGCTTTGAATCGGC
GGACCTGTCGAACCTGTTCAAGTGGTCGTCGCGCACCTGGGCGCTGGGGCCGCTGATCGGCTCCACCATCGCACAGACCG
TGTTCGATGGCGGCCGCAACAGCGCCAACCTCGCCGGTGCCCGTGCCGCGCACGAGGAATCCGTGGCCGGCTACCGGCAG
ACCGTGCTGGTGGCGTTCCGCGAGGTGGAAGACAGCCTGGCGGACGTGCGCTGGCTCAGCCAGCAGGCCGGCGCGCTGGA
CGGCGCACTTGGCGGCGCCCGGCGCGCGGCGCGGATCTCGCGTAGCCGCTACGATGCCGGCGCGGTCGATTACCTGACGG
TGATCGATGCCGACCGTACCGTGCTGCAGTCGCAGCGCGAGGCCAACCAGGTGGCCGGCCTGCGCGCTGCGGCAACGGTG
TCGCTGATCCGCCGGCTGGGCGGCGGCTGGGGCCCGCTGCCGGAGACGGTGGCGGCCGTGCCGGCGCCGGCGGCCGAGGG
CGCGCCGGCATCCCAGGCCCGCTAA

Upstream 100 bases:

>100_bases
CGCCGGTGTTCTATGTGGCGCTGCGCCTGCTGGCTACGCGCGGCCAGCGCCGCGCGGCCACGCAAGAGCAGGGCGCGCAA
CTGACGGCATCGGCTGAATA

Downstream 100 bases:

>100_bases
GCAGCGCGGGACTGGCGCGATGCTTCCCAGTCACTACACTGGAAGCATCGCGCCATGCGTACAGGATGCACGGGGGCGCC
CCGGATGCATCCTGTCCCGC

Product: cation/multidrug efflux system outer membrane porin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MVINMNAPAFSTTNWLPKLATLAAALILAGCSLAPTYKVPETATVPAFKEAEAAQAEGAQWKTATPAEGQHRGDWWKIFG
DAELDRLIDAAGSSNQDLAIAAARLKQARAFTGATEADLYPQLSVGLDPTRAQPSAASQGLPDGTRVPPQTVLKARAFAS
YELDLFGRVASSVNAARAEGEAAEDLYRSVQLALQADVAQAYFALRTLDSERDLLNATIKLREDALSLLKKRYDAGETTD
LDPARAEAELGTARADLAGIERRRANQEHALAVLTGVPPAAFSLPARPFDAAPIAIPAGLPSELLERRPDIAAAERQMAA
ANARIGVAKAAFFPRITLTGLFGFESADLSNLFKWSSRTWALGPLIGSTIAQTVFDGGRNSANLAGARAAHEESVAGYRQ
TVLVAFREVEDSLADVRWLSQQAGALDGALGGARRAARISRSRYDAGAVDYLTVIDADRTVLQSQREANQVAGLRAAATV
SLIRRLGGGWGPLPETVAAVPAPAAEGAPASQAR

Sequences:

>Translated_514_residues
MVINMNAPAFSTTNWLPKLATLAAALILAGCSLAPTYKVPETATVPAFKEAEAAQAEGAQWKTATPAEGQHRGDWWKIFG
DAELDRLIDAAGSSNQDLAIAAARLKQARAFTGATEADLYPQLSVGLDPTRAQPSAASQGLPDGTRVPPQTVLKARAFAS
YELDLFGRVASSVNAARAEGEAAEDLYRSVQLALQADVAQAYFALRTLDSERDLLNATIKLREDALSLLKKRYDAGETTD
LDPARAEAELGTARADLAGIERRRANQEHALAVLTGVPPAAFSLPARPFDAAPIAIPAGLPSELLERRPDIAAAERQMAA
ANARIGVAKAAFFPRITLTGLFGFESADLSNLFKWSSRTWALGPLIGSTIAQTVFDGGRNSANLAGARAAHEESVAGYRQ
TVLVAFREVEDSLADVRWLSQQAGALDGALGGARRAARISRSRYDAGAVDYLTVIDADRTVLQSQREANQVAGLRAAATV
SLIRRLGGGWGPLPETVAAVPAPAAEGAPASQAR
>Mature_514_residues
MVINMNAPAFSTTNWLPKLATLAAALILAGCSLAPTYKVPETATVPAFKEAEAAQAEGAQWKTATPAEGQHRGDWWKIFG
DAELDRLIDAAGSSNQDLAIAAARLKQARAFTGATEADLYPQLSVGLDPTRAQPSAASQGLPDGTRVPPQTVLKARAFAS
YELDLFGRVASSVNAARAEGEAAEDLYRSVQLALQADVAQAYFALRTLDSERDLLNATIKLREDALSLLKKRYDAGETTD
LDPARAEAELGTARADLAGIERRRANQEHALAVLTGVPPAAFSLPARPFDAAPIAIPAGLPSELLERRPDIAAAERQMAA
ANARIGVAKAAFFPRITLTGLFGFESADLSNLFKWSSRTWALGPLIGSTIAQTVFDGGRNSANLAGARAAHEESVAGYRQ
TVLVAFREVEDSLADVRWLSQQAGALDGALGGARRAARISRSRYDAGAVDYLTVIDADRTVLQSQREANQVAGLRAAATV
SLIRRLGGGWGPLPETVAAVPAPAAEGAPASQAR

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=483, Percent_Identity=32.5051759834368, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI2367348, Length=491, Percent_Identity=26.6802443991853, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54225; Mature: 54225

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINMNAPAFSTTNWLPKLATLAAALILAGCSLAPTYKVPETATVPAFKEAEAAQAEGAQ
CEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
WKTATPAEGQHRGDWWKIFGDAELDRLIDAAGSSNQDLAIAAARLKQARAFTGATEADLY
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
PQLSVGLDPTRAQPSAASQGLPDGTRVPPQTVLKARAFASYELDLFGRVASSVNAARAEG
CCEECCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
EAAEDLYRSVQLALQADVAQAYFALRTLDSERDLLNATIKLREDALSLLKKRYDAGETTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDPARAEAELGTARADLAGIERRRANQEHALAVLTGVPPAAFSLPARPFDAAPIAIPAGL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHCCCCCCCCCCCEEECCCC
PSELLERRPDIAAAERQMAAANARIGVAKAAFFPRITLTGLFGFESADLSNLFKWSSRTW
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCE
ALGPLIGSTIAQTVFDGGRNSANLAGARAAHEESVAGYRQTVLVAFREVEDSLADVRWLS
EHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAGALDGALGGARRAARISRSRYDAGAVDYLTVIDADRTVLQSQREANQVAGLRAAATV
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
SLIRRLGGGWGPLPETVAAVPAPAAEGAPASQAR
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVINMNAPAFSTTNWLPKLATLAAALILAGCSLAPTYKVPETATVPAFKEAEAAQAEGAQ
CEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
WKTATPAEGQHRGDWWKIFGDAELDRLIDAAGSSNQDLAIAAARLKQARAFTGATEADLY
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
PQLSVGLDPTRAQPSAASQGLPDGTRVPPQTVLKARAFASYELDLFGRVASSVNAARAEG
CCEECCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
EAAEDLYRSVQLALQADVAQAYFALRTLDSERDLLNATIKLREDALSLLKKRYDAGETTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDPARAEAELGTARADLAGIERRRANQEHALAVLTGVPPAAFSLPARPFDAAPIAIPAGL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHCCCCCCCCCCCEEECCCC
PSELLERRPDIAAAERQMAAANARIGVAKAAFFPRITLTGLFGFESADLSNLFKWSSRTW
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCE
ALGPLIGSTIAQTVFDGGRNSANLAGARAAHEESVAGYRQTVLVAFREVEDSLADVRWLS
EHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAGALDGALGGARRAARISRSRYDAGAVDYLTVIDADRTVLQSQREANQVAGLRAAATV
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
SLIRRLGGGWGPLPETVAAVPAPAAEGAPASQAR
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]