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The map label for this gene is trxB [H]

Identifier: 116695037

GI number: 116695037

Start: 1234829

End: 1236565

Strand: Direct

Name: trxB [H]

Synonym: H16_B1092

Alternate gene names: 116695037

Gene position: 1234829-1236565 (Clockwise)

Preceding gene: 116695033

Following gene: 116695040

Centisome position: 42.4

GC content: 70.41

Gene sequence:

>1737_bases
ATGGCGATTTCGCAGTCGGAGGCAATGGCCCCGGATGAGGACACCGGCCCGGAGGCCGGCGGCGGCCTGGAGGCGCCGTA
TTCCACGCTGGAGTCACGCTGGCACCAGATGTTCCCGCAGCTCGGCGCCGACGACATGGCGCGCGTGCGCCGCTTTGGCA
CGCCGCAGAGCTGGCGCGCGGGCGAGAAGCTCTTTGCCATCGGCGATACGGGCCGGGGCATGTACCTGATCGGCAGCGGC
CGCGTGCGCCTGATGCGGCGCGACGGCCTGGGCCGCGAGCACCAGATCACCGAGCAGGGCGCCGGCCACTTCCTGGCCGA
GGTCGGCACGCTCAGCGGCCGCCCGGCGCTGGTCGACGGCGTGGCCGTGACCGATACCCAGGGCTATGTGATCACGCCAG
AGCGGCTGCGCGCCCTGCTGGTGGCCGAGGCCGAACTGGGCGAGCGCATCATGCGCGCGCTGATCCTGCGCCGCGTGGGG
CTGATCGAATTCGGCAGCGGGCCGGTGCTGGTCGGCCACGGCACCGAGCCGCAGCTGGTGGCACTGCAAGCCTTCCTGCG
GCGCAACGGCTACCCGCATACGGTTATCGATATCGACGCCGAACGCGACTGCTCATTGCTGCTCGACTATGCCAACGCGC
CCGCCAGCGACTTCCCGCTGGTGATCTGCGCCGACGGCCGCGTGCTGCGCGCGCCGGACGAAGGGCAGCTGGCTTCGTGC
CTGGGGCTGTTGCCGGAGTTCGATCCGGTCCATGTCTATGACGTGGTGGTGGTCGGCGCCGGGCCTGCGGGGCTGGCCAC
GGCCGTGTATGCCGCATCCGAAGGCTTGTCGGTGGCGGTGATCGATTGCCGCTCGCCGGGCGGGCAGGCGGGTGCGAGTG
CGCGGATCGAGAACTATCTTGGCTTTCCCACCGGCATCTCCGGACAGGCGCTGGCCGGGCGCGCGTTCGTGCAGGCACTG
AAGTTCGGCGCGCATATCGCCATCCCGCTGGAGGTCAAGGCACTGCATTGCGGCGCGGACCCGATCCGGCTGGAGCTGGC
CGATGGCCGCATGATCCCGACCCACACCGTGGTGATTGCCACCGGCGCGCAGTACCGTCGCCCGGACATCGCCGCGCTGG
AGCACTTTGAAGGGCGTGGTGTCTACTACTGGGCTTCGCCGGTGGAGGCCAAGCTGTGCAAGAACGAGCCGGCGATGCTG
GTGGGCGGCGGCAATTCGGCCGGGCAGGCAGCGGTCTACCTGGCCTCGCACGCGGCGCACGTGCATATGCTGGTGCGCGG
GCCGGGGCTGGCCGCCACCATGTCGCGCTACCTGATCGACCGCATCGGTTCGCTGCCCAATATCACGCTGCACACGCACG
CGCAGATCAGCGCGCTGGCGGGGGAAGGGTGGCTCAGTTCCGTGCGCTACGAATGCCGGGCGGAAAGCCCGGCCCCGGTC
ACGATGGACGTGCGGCACCTGTTCCTGTTCATCGGCGCCGATCCCAATGCGTCGTGGCTGCGCACCTGCAACGTCGAGGT
CGATGACAAGGGCTTCGTGCGCACCGGCGGCGGCGAGCTGGGCTGCGCGTCGGCGGTGCCGTATCCGCTGCAGACCAACG
TGCCGGGCGTGTTTGCCATCGGCGACGTGCGGGCGGGATCGACCAAGCGGGTCGCCGCGGCGGTAGGCGAGGGCGCGGCG
GTGGTGGCGCAGATCCACGACTACCTGGCTCGGGTGCAGGCAGCCGTGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCGATTCTCGCATTCTGCGCGCAGCCGTCTACTATCGATAGGCCGCGCGCAACCGGGAAGATGTGCCCAGGGCAGGCGCG
GGTCCAGACGGGGAGGGAGC

Downstream 100 bases:

>100_bases
GCGCGGGCCACTCAGGCTTGCGCCTCGCGCTCCAGCAACTCGCGCTTGCGCGCCACGCCCCAGCGGTAGCCCGACAGGTT
GCCGTCGCTGCGCACCACGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MAISQSEAMAPDEDTGPEAGGGLEAPYSTLESRWHQMFPQLGADDMARVRRFGTPQSWRAGEKLFAIGDTGRGMYLIGSG
RVRLMRRDGLGREHQITEQGAGHFLAEVGTLSGRPALVDGVAVTDTQGYVITPERLRALLVAEAELGERIMRALILRRVG
LIEFGSGPVLVGHGTEPQLVALQAFLRRNGYPHTVIDIDAERDCSLLLDYANAPASDFPLVICADGRVLRAPDEGQLASC
LGLLPEFDPVHVYDVVVVGAGPAGLATAVYAASEGLSVAVIDCRSPGGQAGASARIENYLGFPTGISGQALAGRAFVQAL
KFGAHIAIPLEVKALHCGADPIRLELADGRMIPTHTVVIATGAQYRRPDIAALEHFEGRGVYYWASPVEAKLCKNEPAML
VGGGNSAGQAAVYLASHAAHVHMLVRGPGLAATMSRYLIDRIGSLPNITLHTHAQISALAGEGWLSSVRYECRAESPAPV
TMDVRHLFLFIGADPNASWLRTCNVEVDDKGFVRTGGGELGCASAVPYPLQTNVPGVFAIGDVRAGSTKRVAAAVGEGAA
VVAQIHDYLARVQAAVAR

Sequences:

>Translated_578_residues
MAISQSEAMAPDEDTGPEAGGGLEAPYSTLESRWHQMFPQLGADDMARVRRFGTPQSWRAGEKLFAIGDTGRGMYLIGSG
RVRLMRRDGLGREHQITEQGAGHFLAEVGTLSGRPALVDGVAVTDTQGYVITPERLRALLVAEAELGERIMRALILRRVG
LIEFGSGPVLVGHGTEPQLVALQAFLRRNGYPHTVIDIDAERDCSLLLDYANAPASDFPLVICADGRVLRAPDEGQLASC
LGLLPEFDPVHVYDVVVVGAGPAGLATAVYAASEGLSVAVIDCRSPGGQAGASARIENYLGFPTGISGQALAGRAFVQAL
KFGAHIAIPLEVKALHCGADPIRLELADGRMIPTHTVVIATGAQYRRPDIAALEHFEGRGVYYWASPVEAKLCKNEPAML
VGGGNSAGQAAVYLASHAAHVHMLVRGPGLAATMSRYLIDRIGSLPNITLHTHAQISALAGEGWLSSVRYECRAESPAPV
TMDVRHLFLFIGADPNASWLRTCNVEVDDKGFVRTGGGELGCASAVPYPLQTNVPGVFAIGDVRAGSTKRVAAAVGEGAA
VVAQIHDYLARVQAAVAR
>Mature_577_residues
AISQSEAMAPDEDTGPEAGGGLEAPYSTLESRWHQMFPQLGADDMARVRRFGTPQSWRAGEKLFAIGDTGRGMYLIGSGR
VRLMRRDGLGREHQITEQGAGHFLAEVGTLSGRPALVDGVAVTDTQGYVITPERLRALLVAEAELGERIMRALILRRVGL
IEFGSGPVLVGHGTEPQLVALQAFLRRNGYPHTVIDIDAERDCSLLLDYANAPASDFPLVICADGRVLRAPDEGQLASCL
GLLPEFDPVHVYDVVVVGAGPAGLATAVYAASEGLSVAVIDCRSPGGQAGASARIENYLGFPTGISGQALAGRAFVQALK
FGAHIAIPLEVKALHCGADPIRLELADGRMIPTHTVVIATGAQYRRPDIAALEHFEGRGVYYWASPVEAKLCKNEPAMLV
GGGNSAGQAAVYLASHAAHVHMLVRGPGLAATMSRYLIDRIGSLPNITLHTHAQISALAGEGWLSSVRYECRAESPAPVT
MDVRHLFLFIGADPNASWLRTCNVEVDDKGFVRTGGGELGCASAVPYPLQTNVPGVFAIGDVRAGSTKRVAAAVGEGAAV
VAQIHDYLARVQAAVAR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=30.188679245283, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081763, Length=340, Percent_Identity=30.5882352941176, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321898, Length=333, Percent_Identity=27.3273273273273, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320560, Length=337, Percent_Identity=27.299703264095, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 61079; Mature: 60948

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISQSEAMAPDEDTGPEAGGGLEAPYSTLESRWHQMFPQLGADDMARVRRFGTPQSWRA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
GEKLFAIGDTGRGMYLIGSGRVRLMRRDGLGREHQITEQGAGHFLAEVGTLSGRPALVDG
CCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCHHHCCCCHHHHHHHCCCCCCEEECC
VAVTDTQGYVITPERLRALLVAEAELGERIMRALILRRVGLIEFGSGPVLVGHGTEPQLV
EEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHH
ALQAFLRRNGYPHTVIDIDAERDCSLLLDYANAPASDFPLVICADGRVLRAPDEGQLASC
HHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHH
LGLLPEFDPVHVYDVVVVGAGPAGLATAVYAASEGLSVAVIDCRSPGGQAGASARIENYL
HHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHC
GFPTGISGQALAGRAFVQALKFGAHIAIPLEVKALHCGADPIRLELADGRMIPTHTVVIA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEECCCEECCCEEEEEE
TGAQYRRPDIAALEHFEGRGVYYWASPVEAKLCKNEPAMLVGGGNSAGQAAVYLASHAAH
CCCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHCCCCEEEEECCCCCCCEEEEEEECCEE
VHMLVRGPGLAATMSRYLIDRIGSLPNITLHTHAQISALAGEGWLSSVRYECRAESPAPV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHHEECCCCCCCE
TMDVRHLFLFIGADPNASWLRTCNVEVDDKGFVRTGGGELGCASAVPYPLQTNVPGVFAI
EEEEEEEEEEEECCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
GDVRAGSTKRVAAAVGEGAAVVAQIHDYLARVQAAVAR
ECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AISQSEAMAPDEDTGPEAGGGLEAPYSTLESRWHQMFPQLGADDMARVRRFGTPQSWRA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
GEKLFAIGDTGRGMYLIGSGRVRLMRRDGLGREHQITEQGAGHFLAEVGTLSGRPALVDG
CCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCHHHCCCCHHHHHHHCCCCCCEEECC
VAVTDTQGYVITPERLRALLVAEAELGERIMRALILRRVGLIEFGSGPVLVGHGTEPQLV
EEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHH
ALQAFLRRNGYPHTVIDIDAERDCSLLLDYANAPASDFPLVICADGRVLRAPDEGQLASC
HHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHH
LGLLPEFDPVHVYDVVVVGAGPAGLATAVYAASEGLSVAVIDCRSPGGQAGASARIENYL
HHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHC
GFPTGISGQALAGRAFVQALKFGAHIAIPLEVKALHCGADPIRLELADGRMIPTHTVVIA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEECCCEECCCEEEEEE
TGAQYRRPDIAALEHFEGRGVYYWASPVEAKLCKNEPAMLVGGGNSAGQAAVYLASHAAH
CCCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHCCCCEEEEECCCCCCCEEEEEEECCEE
VHMLVRGPGLAATMSRYLIDRIGSLPNITLHTHAQISALAGEGWLSSVRYECRAESPAPV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHHEECCCCCCCE
TMDVRHLFLFIGADPNASWLRTCNVEVDDKGFVRTGGGELGCASAVPYPLQTNVPGVFAI
EEEEEEEEEEEECCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
GDVRAGSTKRVAAAVGEGAAVVAQIHDYLARVQAAVAR
ECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]