Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 116694976

GI number: 116694976

Start: 1164415

End: 1165395

Strand: Direct

Name: qor [H]

Synonym: H16_B1031

Alternate gene names: 116694976

Gene position: 1164415-1165395 (Clockwise)

Preceding gene: 116694975

Following gene: 116694977

Centisome position: 39.98

GC content: 65.65

Gene sequence:

>981_bases
ATGGCGAAAATCGTTAAGTTCTATGAAACCGGCGGACCCGACGTCCTTTGTCTTGAGGACGGCAGCGTTGGTGAGCCCGG
AGCGGGGGAGGTCCGCGTCCGCCACGTGGCGGCAGGCCTGAACTTCGCCGATACCTACTTCCGCAGCGGCACGTACAAGG
TGCCGCTGCCCAGCGGCATCGGCAACGAGGCCGCTGGCGTGATTGAGGCTGTCGGTGCCGGCGTCACCCATCTGGCGGTC
GGCGACCGTGTGACCTACACCGGATTTACCAACACGCTGGGCGCCTACAGCACGGAGCGGCTGATCTCTGCCGGTCCGCT
GATCAGGCTGCCGCAGGCAATCAGTTGCGAAGTCGCGGCGGCCATGACCATGCGCGGTTTGTCGGCGGCCTACCTGATGC
GCCGGATCTACCCCTTCAAGGCGGGCGACTCCATCCTGCTGCATGCCGCGGCAGGTGGTGTTGGCCTGATCGTTGCGCAG
TGGGCCAAATTGTTGGGGCTGACGGTGATCGGCACGGTTTCGACCGATGCCAAGGCCGAAGTGGCGCGCGCCCACGGCTG
TGACCACACCATCAACTACAGCCATGAGGACGTGGCCAGGCGCGTGCGGGAACTGACCGACGGCGTGGGCGTGAACGTGG
TCTTCGACAGCGTGGGCAAGGACACCTTCATGTCCTCGCTGGACTCCCTCAGGCGCCGCGGCCTGCTGGTGTGCGTGGGT
TTCGCCTCCGGCCCGGTAACCGGGTTCGATCCGGCAATTCTGGCCCGCAAGGGCTCGGCGTTCCTGACACGCCCGGGCCT
GGCCGACTATATCGCCGATCCTGCCGAGAAGGCGGAACTGGTCGGCGAGCTGTTCGGCCACGTGGCGGCTGGCCGCATCC
GCATCGGGATCAATCAGCGCTATGCCCTGGAGGATGCCGTGCAGGCACACCGGGACCTGGAGTCGCGGAAGACCACCGGC
TCGTCCATTTTCGTGATTTGA

Upstream 100 bases:

>100_bases
TCAACCCATCCACTGCATCCCCAAACCGGTTTGTCCTTCGGCGAGCTCAACCGCCGATCCGCAGGTGAACGGTCATATTC
GATAGAGAACAGGAGACGGC

Downstream 100 bases:

>100_bases
CGGCACGAAGCAGCTGTCTCATCCATCGACCTTCTCAAGATTCACATCTCAACCCGGAGATCCACCAACATGAACTTCCT
TGACGGCCACCTGTATCCCG

Product: NADPH:quinone reductase or related Zn-dependent oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAKIVKFYETGGPDVLCLEDGSVGEPGAGEVRVRHVAAGLNFADTYFRSGTYKVPLPSGIGNEAAGVIEAVGAGVTHLAV
GDRVTYTGFTNTLGAYSTERLISAGPLIRLPQAISCEVAAAMTMRGLSAAYLMRRIYPFKAGDSILLHAAAGGVGLIVAQ
WAKLLGLTVIGTVSTDAKAEVARAHGCDHTINYSHEDVARRVRELTDGVGVNVVFDSVGKDTFMSSLDSLRRRGLLVCVG
FASGPVTGFDPAILARKGSAFLTRPGLADYIADPAEKAELVGELFGHVAAGRIRIGINQRYALEDAVQAHRDLESRKTTG
SSIFVI

Sequences:

>Translated_326_residues
MAKIVKFYETGGPDVLCLEDGSVGEPGAGEVRVRHVAAGLNFADTYFRSGTYKVPLPSGIGNEAAGVIEAVGAGVTHLAV
GDRVTYTGFTNTLGAYSTERLISAGPLIRLPQAISCEVAAAMTMRGLSAAYLMRRIYPFKAGDSILLHAAAGGVGLIVAQ
WAKLLGLTVIGTVSTDAKAEVARAHGCDHTINYSHEDVARRVRELTDGVGVNVVFDSVGKDTFMSSLDSLRRRGLLVCVG
FASGPVTGFDPAILARKGSAFLTRPGLADYIADPAEKAELVGELFGHVAAGRIRIGINQRYALEDAVQAHRDLESRKTTG
SSIFVI
>Mature_325_residues
AKIVKFYETGGPDVLCLEDGSVGEPGAGEVRVRHVAAGLNFADTYFRSGTYKVPLPSGIGNEAAGVIEAVGAGVTHLAVG
DRVTYTGFTNTLGAYSTERLISAGPLIRLPQAISCEVAAAMTMRGLSAAYLMRRIYPFKAGDSILLHAAAGGVGLIVAQW
AKLLGLTVIGTVSTDAKAEVARAHGCDHTINYSHEDVARRVRELTDGVGVNVVFDSVGKDTFMSSLDSLRRRGLLVCVGF
ASGPVTGFDPAILARKGSAFLTRPGLADYIADPAEKAELVGELFGHVAAGRIRIGINQRYALEDAVQAHRDLESRKTTGS
SIFVI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=318, Percent_Identity=27.9874213836478, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI13236495, Length=318, Percent_Identity=27.9874213836478, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=28.7974683544304, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=25.609756097561, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=25.609756097561, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI194239676, Length=208, Percent_Identity=33.1730769230769, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI28557745, Length=237, Percent_Identity=31.2236286919831, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=28.1976744186047, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI67078404, Length=226, Percent_Identity=30.0884955752212, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI67078406, Length=220, Percent_Identity=29.5454545454545, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=48.1707317073171, Blast_Score=292, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17507255, Length=317, Percent_Identity=27.4447949526814, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17536829, Length=310, Percent_Identity=27.0967741935484, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=40.3669724770642, Blast_Score=223, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34308; Mature: 34176

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVKFYETGGPDVLCLEDGSVGEPGAGEVRVRHVAAGLNFADTYFRSGTYKVPLPSGI
CCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCEEEECCCCCC
GNEAAGVIEAVGAGVTHLAVGDRVTYTGFTNTLGAYSTERLISAGPLIRLPQAISCEVAA
CCHHHHHHHHHCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHCCCCEECCCHHHHHHHH
AMTMRGLSAAYLMRRIYPFKAGDSILLHAAAGGVGLIVAQWAKLLGLTVIGTVSTDAKAE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCCHHHH
VARAHGCDHTINYSHEDVARRVRELTDGVGVNVVFDSVGKDTFMSSLDSLRRRGLLVCVG
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEEE
FASGPVTGFDPAILARKGSAFLTRPGLADYIADPAEKAELVGELFGHVAAGRIRIGINQR
ECCCCCCCCCHHHHEECCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCC
YALEDAVQAHRDLESRKTTGSSIFVI
HHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure 
AKIVKFYETGGPDVLCLEDGSVGEPGAGEVRVRHVAAGLNFADTYFRSGTYKVPLPSGI
CCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCEEEECCCCCC
GNEAAGVIEAVGAGVTHLAVGDRVTYTGFTNTLGAYSTERLISAGPLIRLPQAISCEVAA
CCHHHHHHHHHCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHCCCCEECCCHHHHHHHH
AMTMRGLSAAYLMRRIYPFKAGDSILLHAAAGGVGLIVAQWAKLLGLTVIGTVSTDAKAE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCCHHHH
VARAHGCDHTINYSHEDVARRVRELTDGVGVNVVFDSVGKDTFMSSLDSLRRRGLLVCVG
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEEE
FASGPVTGFDPAILARKGSAFLTRPGLADYIADPAEKAELVGELFGHVAAGRIRIGINQR
ECCCCCCCCCHHHHEECCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCC
YALEDAVQAHRDLESRKTTGSSIFVI
HHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]